Sodium oligomannate's amelioration of reproductive and metabolic phenotypes in a letrozole-induced PCOS-like mouse model depends on the gut microbiome
In conclusion, the hyperinsulinemia and hyperandrogenemia of PCOS-like mice were alleviated by GV-971 intervention, which was associated with mitigating bile acid metabolism and modulating gut microbiota.PMID:38630889 | DOI:10.1093/biolre/ioae058 (Source: Reproductive Biology)
Source: Reproductive Biology - April 17, 2024 Category: Reproduction Medicine Authors: Zhi Li Yan Liu Yang Wang Qingqing Cai Yuhui Wang Yixuan Bai Haiou Liu Congjian Xu Feifei Zhang Source Type: research

The effect of polycystic ovarian syndrome on fibrocystic breast changes in postmenopausal women
CONCLUSION: Postmenopausal women with PCOS have a higher risk of developing FCCs. Further studies are needed to improve the differentiation of benign FCCs from malignant lesions on imaging for postmenopausal women with PCOS who develop FCCs.PMID:38628327 | PMC:PMC11017995 | DOI:10.1080/08998280.2024.2308458 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - April 17, 2024 Category: Universities & Medical Training Authors: Brittany Dang Madison Clewis Brittany Miles Quan Nguyen Source Type: research

Sodium oligomannate's amelioration of reproductive and metabolic phenotypes in a letrozole-induced PCOS-like mouse model depends on the gut microbiome
In conclusion, the hyperinsulinemia and hyperandrogenemia of PCOS-like mice were alleviated by GV-971 intervention, which was associated with mitigating bile acid metabolism and modulating gut microbiota.PMID:38630889 | DOI:10.1093/biolre/ioae058 (Source: Biology of Reproduction)
Source: Biology of Reproduction - April 17, 2024 Category: Reproduction Medicine Authors: Zhi Li Yan Liu Yang Wang Qingqing Cai Yuhui Wang Yixuan Bai Haiou Liu Congjian Xu Feifei Zhang Source Type: research

Sodium oligomannate's amelioration of reproductive and metabolic phenotypes in a letrozole-induced PCOS-like mouse model depends on the gut microbiome
In conclusion, the hyperinsulinemia and hyperandrogenemia of PCOS-like mice were alleviated by GV-971 intervention, which was associated with mitigating bile acid metabolism and modulating gut microbiota.PMID:38630889 | DOI:10.1093/biolre/ioae058 (Source: Reproductive Biology)
Source: Reproductive Biology - April 17, 2024 Category: Reproduction Medicine Authors: Zhi Li Yan Liu Yang Wang Qingqing Cai Yuhui Wang Yixuan Bai Haiou Liu Congjian Xu Feifei Zhang Source Type: research

The effect of polycystic ovarian syndrome on fibrocystic breast changes in postmenopausal women
CONCLUSION: Postmenopausal women with PCOS have a higher risk of developing FCCs. Further studies are needed to improve the differentiation of benign FCCs from malignant lesions on imaging for postmenopausal women with PCOS who develop FCCs.PMID:38628327 | PMC:PMC11017995 | DOI:10.1080/08998280.2024.2308458 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - April 17, 2024 Category: Universities & Medical Training Authors: Brittany Dang Madison Clewis Brittany Miles Quan Nguyen Source Type: research

The effect of polycystic ovarian syndrome on fibrocystic breast changes in postmenopausal women
CONCLUSION: Postmenopausal women with PCOS have a higher risk of developing FCCs. Further studies are needed to improve the differentiation of benign FCCs from malignant lesions on imaging for postmenopausal women with PCOS who develop FCCs.PMID:38628327 | PMC:PMC11017995 | DOI:10.1080/08998280.2024.2308458 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - April 17, 2024 Category: Universities & Medical Training Authors: Brittany Dang Madison Clewis Brittany Miles Quan Nguyen Source Type: research

The effect of polycystic ovarian syndrome on fibrocystic breast changes in postmenopausal women
CONCLUSION: Postmenopausal women with PCOS have a higher risk of developing FCCs. Further studies are needed to improve the differentiation of benign FCCs from malignant lesions on imaging for postmenopausal women with PCOS who develop FCCs.PMID:38628327 | PMC:PMC11017995 | DOI:10.1080/08998280.2024.2308458 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - April 17, 2024 Category: Universities & Medical Training Authors: Brittany Dang Madison Clewis Brittany Miles Quan Nguyen Source Type: research

The effect of polycystic ovarian syndrome on fibrocystic breast changes in postmenopausal women
CONCLUSION: Postmenopausal women with PCOS have a higher risk of developing FCCs. Further studies are needed to improve the differentiation of benign FCCs from malignant lesions on imaging for postmenopausal women with PCOS who develop FCCs.PMID:38628327 | PMC:PMC11017995 | DOI:10.1080/08998280.2024.2308458 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - April 17, 2024 Category: Universities & Medical Training Authors: Brittany Dang Madison Clewis Brittany Miles Quan Nguyen Source Type: research

The effect of polycystic ovarian syndrome on fibrocystic breast changes in postmenopausal women
CONCLUSION: Postmenopausal women with PCOS have a higher risk of developing FCCs. Further studies are needed to improve the differentiation of benign FCCs from malignant lesions on imaging for postmenopausal women with PCOS who develop FCCs.PMID:38628327 | PMC:PMC11017995 | DOI:10.1080/08998280.2024.2308458 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - April 17, 2024 Category: Universities & Medical Training Authors: Brittany Dang Madison Clewis Brittany Miles Quan Nguyen Source Type: research

Laser and Light-Based Therapies for Hirsutism Management in Women With Polycystic Ovarian Syndrome
This Systematic Review synthesizes the existing literature regarding the effectiveness of laser and light hair reduction therapies, either as stand-alone treatments or in combination with systemic agents, in treating hirsutism for women with polycystic ovary syndrome. (Source: JAMA Dermatology)
Source: JAMA Dermatology - April 17, 2024 Category: Dermatology Source Type: research

Integrated lipid metabolomics and proteomics analysis reveal the pathogenesis of polycystic ovary syndrome
Polycystic ovary syndrome (PCOS) is an endocrinological and metabolic disorder that can lead to female infertility. Lipid metabolomics and proteomics are the new disciplines in systems biology aimed to discove... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - April 17, 2024 Category: Research Authors: Yu Qian, Yun Tong, Yaqiong Zeng, Jingyu Huang, Kailu Liu, Ying Xie, Juan Chen, Mengya Gao, Li Liu, Juan Zhao, Yanli Hong and Xiaowei Nie Tags: Research Source Type: research

Genome-wide association study (GWAS) identified PCOS susceptibility variants and replicates reported risk variants
ConclusionThe study suggests that multiple variants play an important role in PCOS pathogenesis and emphasizes the importance of further genetic studies among Indian subpopulations.  The study also validates two previously reported SNPs in the Indian population.What this study adds to clinical workStudy summarizes the importance of candidate gene markers validated by replication and in-silico functional study, significantly involved in PCOS pathogenesis in the studied population. These markers can be used in the future as diagnostic markers for clinical phenotype identification. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - April 16, 2024 Category: OBGYN Source Type: research

Unmet clinical needs in women with polycystic ovary syndrome in regard to mental health: a cross-sectional study
ConclusionWomen affected by PCOS are not properly managed according to ESHRE guideline in regard to mental health issues. Overall consultation rates and corresponding satisfaction with management were poor, highlighting the need for significant improvements in healthcare provision. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - April 16, 2024 Category: OBGYN Source Type: research

Survey on Value Elements Provided by Artificial Intelligence and Their Eligibility for Insurance Coverage With an Emphasis on Patient-Centered Outcomes
CONCLUSION: There is currently limited demand for insurance coverage for AI that demonstrates benefits in terms of non-clinical PCOs.PMID:38627874 | DOI:10.3348/kjr.2023.1281 (Source: Korean J Radiol)
Source: Korean J Radiol - April 16, 2024 Category: Radiology Authors: Hoyol Jhang So Jin Park Ah-Ram Sul Hye Young Jang Seong Ho Park Source Type: research

Impact of dehydroepiandrosterone sulfate and free androgen index on pregnancy and neonatal outcomes in PCOS patients
CONCLUSION: In conclusion, PCOS patients with biochemical hyperandrogenism show unsatisfactory clinical PR and CLBR when undergoing assisted reproductive technology (ART). This may be attributed to the influence of both adrenal-derived DHEAS and ovarian-derived FAI on the unfavorable pregnancy outcomes.PMID:38627777 | DOI:10.1186/s12958-024-01212-y (Source: Reproductive Biology)
Source: Reproductive Biology - April 16, 2024 Category: Reproduction Medicine Authors: Wen Zhao Zeting Li Bing Cai Canquan Zhou Qingyun Mai Source Type: research