Circulating levels of irisin and Meteorin-like protein in PCOS and its correlation with metabolic parameters
CONCLUSIONS: Although irisin seems to be a promising biomarker, inconsistent research limits its value in clinical use in the assessment or treatment of obesity. Metrnl level was not affected in the study population, but it might be connected to the severity of metabolic disturbances.PMID:38646985 | DOI:10.5603/ep.99111 (Source: Endokrynologia Polska)
Source: Endokrynologia Polska - April 22, 2024 Category: Endocrinology Authors: Katarzyna Paczkowska Joachim Sobczuk Katarzyna Zawadzka Diana J ędrzejuk Agnieszka Zembska Jacek Konieczny Dorota Kaszubkiewicz-Ward ęga Marek Bolanowski Jacek Daroszewski Source Type: research
Circulating levels of irisin and Meteorin-like protein in PCOS and its correlation with metabolic parameters
CONCLUSIONS: Although irisin seems to be a promising biomarker, inconsistent research limits its value in clinical use in the assessment or treatment of obesity. Metrnl level was not affected in the study population, but it might be connected to the severity of metabolic disturbances.PMID:38646985 | DOI:10.5603/ep.99111 (Source: Endokrynologia Polska)
Source: Endokrynologia Polska - April 22, 2024 Category: Endocrinology Authors: Katarzyna Paczkowska Joachim Sobczuk Katarzyna Zawadzka Diana J ędrzejuk Agnieszka Zembska Jacek Konieczny Dorota Kaszubkiewicz-Ward ęga Marek Bolanowski Jacek Daroszewski Source Type: research
Circulating levels of irisin and Meteorin-like protein in PCOS and its correlation with metabolic parameters
CONCLUSIONS: Although irisin seems to be a promising biomarker, inconsistent research limits its value in clinical use in the assessment or treatment of obesity. Metrnl level was not affected in the study population, but it might be connected to the severity of metabolic disturbances.PMID:38646985 | DOI:10.5603/ep.99111 (Source: Endokrynologia Polska)
Source: Endokrynologia Polska - April 22, 2024 Category: Endocrinology Authors: Katarzyna Paczkowska Joachim Sobczuk Katarzyna Zawadzka Diana J ędrzejuk Agnieszka Zembska Jacek Konieczny Dorota Kaszubkiewicz-Ward ęga Marek Bolanowski Jacek Daroszewski Source Type: research
Circulating levels of irisin and Meteorin-like protein in PCOS and its correlation with metabolic parameters
CONCLUSIONS: Although irisin seems to be a promising biomarker, inconsistent research limits its value in clinical use in the assessment or treatment of obesity. Metrnl level was not affected in the study population, but it might be connected to the severity of metabolic disturbances.PMID:38646985 | DOI:10.5603/ep.99111 (Source: Endokrynologia Polska)
Source: Endokrynologia Polska - April 22, 2024 Category: Endocrinology Authors: Katarzyna Paczkowska Joachim Sobczuk Katarzyna Zawadzka Diana J ędrzejuk Agnieszka Zembska Jacek Konieczny Dorota Kaszubkiewicz-Ward ęga Marek Bolanowski Jacek Daroszewski Source Type: research
Yishen Huatan Huoxue decoction and quercetin ameliorate decidualization dysfunction in polycystic ovary syndrome: A comprehensive investigation combining clinical trial and experimental studies
This study provides valuable molecular insights of YHHD and highlight the therapeutic potential of quercetin in treating decidualization dysfunction in PCOS.PMID:38644207 | DOI:10.5582/ddt.2024.01003 (Source: Drug Discoveries and Therapeutics)
Source: Drug Discoveries and Therapeutics - April 21, 2024 Category: Drugs & Pharmacology Authors: Jing Wang Lisha Li Jing Zhou Xinyao Pan Qing Qi Hongmei Sun Ling Wang Source Type: research
A meta-analysis of bariatric surgery in patients with obesity and polycystic ovary syndrome
This study evaluated the efficacy of bariatric surgery on obesity complicated with PCOS through meta-analysis. PubMed, Cochrane, EMbase, and WOS databases were searched from 2012 to November 2022. Studies on the efficacy of bariatric surgery in the treatment of obesity combined with PCOS were included. Outcome indicators included menstrual abnormalities, BMI, free testosterone, hypertrichosis, and ovarian volume. Methodological quality of the included studies was evaluated, and statistical analysis was performed using RevMan 5.3 software. Finally, 9 studies were included, and the results of meta-analysis were as follows: A...
Source: Asian Journal of Surgery - April 19, 2024 Category: Surgery Authors: Mengyue Chen Qiucheng Jia Yao Chen Wulin Shan Huimin Tang Tingwei Xing Weiwei Wei Hong Zheng Wenpeng Xue Ruxia Shi Bairong Xia Jiming Chen Source Type: research
Plastic-related Endocrine Disrupting Chemicals Significantly Related to the increased Risk of Estrogen-dependent Diseases in Women
CONCLUSION: Increased serum, urinary, or dietary concentration of MBzP and MEHP in women is significantly associated with endometriosis risk. Increased cadmium concentration is associated with endometrial cancer risk.PMID:38640992 | DOI:10.1016/j.envres.2024.118966 (Source: Environmental Research)
Source: Environmental Research - April 19, 2024 Category: Environmental Health Authors: Natasha Chitakwa Mohammed Alqudaimi Mazhar Sultan Di Wu Source Type: research
Polycystic ovary syndrome (PCOS): progress towards a better understanding and treatment of the syndrome
This article highlights how an altered fetal environment (prenatal exposure to high levels of anti-Müllerian hormone) can contribute to the onset of PCOS in adulthood and lead to the transgenerational transmission of neuroendocrine and metabolic traits through alterations in the DNA methylation process.The originality of the translational findings summarized here involves the identification of potential biomarkers for early diagnosis of the syndrome, in addition to the validation of a promising therapeutic avenue in a preclinical model of PCOS, which can improve the management of patients suffering from the syndrome.PMID:...
Source: Comptes Rendus Biologies - April 19, 2024 Category: Biology Authors: Nour El Houda Mimouni Paolo Giacobini Source Type: research
Polycystic ovary syndrome (PCOS): progress towards a better understanding and treatment of the syndrome
This article highlights how an altered fetal environment (prenatal exposure to high levels of anti-Müllerian hormone) can contribute to the onset of PCOS in adulthood and lead to the transgenerational transmission of neuroendocrine and metabolic traits through alterations in the DNA methylation process.The originality of the translational findings summarized here involves the identification of potential biomarkers for early diagnosis of the syndrome, in addition to the validation of a promising therapeutic avenue in a preclinical model of PCOS, which can improve the management of patients suffering from the syndrome.PMID:...
Source: Comptes Rendus Biologies - April 19, 2024 Category: Biology Authors: Nour El Houda Mimouni Paolo Giacobini Source Type: research
Polycystic ovary syndrome (PCOS): progress towards a better understanding and treatment of the syndrome
This article highlights how an altered fetal environment (prenatal exposure to high levels of anti-Müllerian hormone) can contribute to the onset of PCOS in adulthood and lead to the transgenerational transmission of neuroendocrine and metabolic traits through alterations in the DNA methylation process.The originality of the translational findings summarized here involves the identification of potential biomarkers for early diagnosis of the syndrome, in addition to the validation of a promising therapeutic avenue in a preclinical model of PCOS, which can improve the management of patients suffering from the syndrome.PMID:...
Source: Comptes Rendus Biologies - April 19, 2024 Category: Biology Authors: Nour El Houda Mimouni Paolo Giacobini Source Type: research
Polycystic ovary syndrome (PCOS): progress towards a better understanding and treatment of the syndrome
This article highlights how an altered fetal environment (prenatal exposure to high levels of anti-Müllerian hormone) can contribute to the onset of PCOS in adulthood and lead to the transgenerational transmission of neuroendocrine and metabolic traits through alterations in the DNA methylation process.The originality of the translational findings summarized here involves the identification of potential biomarkers for early diagnosis of the syndrome, in addition to the validation of a promising therapeutic avenue in a preclinical model of PCOS, which can improve the management of patients suffering from the syndrome.PMID:...
Source: Comptes Rendus Biologies - April 19, 2024 Category: Biology Authors: Nour El Houda Mimouni Paolo Giacobini Source Type: research
Polycystic ovary syndrome (PCOS): progress towards a better understanding and treatment of the syndrome
This article highlights how an altered fetal environment (prenatal exposure to high levels of anti-Müllerian hormone) can contribute to the onset of PCOS in adulthood and lead to the transgenerational transmission of neuroendocrine and metabolic traits through alterations in the DNA methylation process.The originality of the translational findings summarized here involves the identification of potential biomarkers for early diagnosis of the syndrome, in addition to the validation of a promising therapeutic avenue in a preclinical model of PCOS, which can improve the management of patients suffering from the syndrome.PMID:...
Source: Comptes Rendus Biologies - April 19, 2024 Category: Biology Authors: Nour El Houda Mimouni Paolo Giacobini Source Type: research
Polycystic ovary syndrome (PCOS): progress towards a better understanding and treatment of the syndrome
This article highlights how an altered fetal environment (prenatal exposure to high levels of anti-Müllerian hormone) can contribute to the onset of PCOS in adulthood and lead to the transgenerational transmission of neuroendocrine and metabolic traits through alterations in the DNA methylation process.The originality of the translational findings summarized here involves the identification of potential biomarkers for early diagnosis of the syndrome, in addition to the validation of a promising therapeutic avenue in a preclinical model of PCOS, which can improve the management of patients suffering from the syndrome.PMID:...
Source: Comptes Rendus Biologies - April 19, 2024 Category: Biology Authors: Nour El Houda Mimouni Paolo Giacobini Source Type: research
Polycystic ovary syndrome (PCOS): progress towards a better understanding and treatment of the syndrome
This article highlights how an altered fetal environment (prenatal exposure to high levels of anti-Müllerian hormone) can contribute to the onset of PCOS in adulthood and lead to the transgenerational transmission of neuroendocrine and metabolic traits through alterations in the DNA methylation process.The originality of the translational findings summarized here involves the identification of potential biomarkers for early diagnosis of the syndrome, in addition to the validation of a promising therapeutic avenue in a preclinical model of PCOS, which can improve the management of patients suffering from the syndrome.PMID:...
Source: Comptes Rendus Biologies - April 19, 2024 Category: Biology Authors: Nour El Houda Mimouni Paolo Giacobini Source Type: research
