Polycystic ovary syndrome (PCOS): progress towards  a better understanding and treatment of the syndrome

This article highlights how an altered fetal environment (prenatal exposure to high levels of anti-Müllerian hormone) can contribute to the onset of PCOS in adulthood and lead to the transgenerational transmission of neuroendocrine and metabolic traits through alterations in the DNA methylation process.The originality of the translational findings summarized here involves the identification of potential biomarkers for early diagnosis of the syndrome, in addition to the validation of a promising therapeutic avenue in a preclinical model of PCOS, which can improve the management of patients suffering from the syndrome.PMID:38639155 | DOI:10.5802/crbiol.147
Source: Comptes Rendus Biologies - Category: Biology Authors: Source Type: research