Individualized Weight Management and Its Impact on Pregnancy Outcomes in Overweight/Obese Infertile Women: A Retrospective Study
CONCLUSIONS: Individualized weight management enhances pregnancy outcomes in overweight/obese infertile women. Achieving a reduction in body weight by 10% or more, combined with effective control of visceral fat, proves important in improving pregnancy outcomes. Excess visceral fat emerges as an adverse factor impacting successful pregnancy.PMID:38551442 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 29, 2024 Category: Complementary Medicine Authors: Huimei Wu Xiaoli Wang Ran Sun Xiaoqian Fu Bin Zeng Fu Hang Qianyi Huang Li Jiang Qizhi Ou Aiping Qin Liuming Li Mujun Li Source Type: research
Individualized Weight Management and Its Impact on Pregnancy Outcomes in Overweight/Obese Infertile Women: A Retrospective Study
CONCLUSIONS: Individualized weight management enhances pregnancy outcomes in overweight/obese infertile women. Achieving a reduction in body weight by 10% or more, combined with effective control of visceral fat, proves important in improving pregnancy outcomes. Excess visceral fat emerges as an adverse factor impacting successful pregnancy.PMID:38551442 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 29, 2024 Category: Complementary Medicine Authors: Huimei Wu Xiaoli Wang Ran Sun Xiaoqian Fu Bin Zeng Fu Hang Qianyi Huang Li Jiang Qizhi Ou Aiping Qin Liuming Li Mujun Li Source Type: research
Individualized Weight Management and Its Impact on Pregnancy Outcomes in Overweight/Obese Infertile Women: A Retrospective Study
CONCLUSIONS: Individualized weight management enhances pregnancy outcomes in overweight/obese infertile women. Achieving a reduction in body weight by 10% or more, combined with effective control of visceral fat, proves important in improving pregnancy outcomes. Excess visceral fat emerges as an adverse factor impacting successful pregnancy.PMID:38551442 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 29, 2024 Category: Complementary Medicine Authors: Huimei Wu Xiaoli Wang Ran Sun Xiaoqian Fu Bin Zeng Fu Hang Qianyi Huang Li Jiang Qizhi Ou Aiping Qin Liuming Li Mujun Li Source Type: research
Modulation of the RAC1/MAPK/ERK signalling pathway by farnesyl diphosphate synthase regulates granulosa cells proliferation in polycystic ovary syndrome
AbstractPolycystic ovary syndrome (PCOS) is a complex gynaecological endocrine disease that occurs in women of childbearing age. The pathogenesis of PCOS is still unclear and further exploration is needed. Here, proteomic analysis indicated that the expression of farnesyl diphosphate synthase (FDPS) protein in ovarian tissue of PCOS mice was significantly decreased. The purpose of this study is to investigate the relationship between potential biomarkers of PCOS and granulosa cells (GCs) function. The mechanisms by which FDPS affected the proliferation of granulosa cells were also explored both in vitro and in vivo. We fou...
Source: Human Cell - March 29, 2024 Category: Cytology Source Type: research
Efficacy of optimal nutraceutical combination in treating PCOS characteristics: an in-silico assessment
Polycystic ovary syndrome (PCOS) is a serious health condition affecting women of reproductive age. High prevalence of PCOS and associated metabolic complications needs effective treatment and management. This... (Source: BMC Endocrine Disorders)
Source: BMC Endocrine Disorders - March 29, 2024 Category: Endocrinology Authors: Abha Saxena, Manali Sherkane, Rachana Bhoite, Manasa Premasudha Sadananda, Vinita Satyavrat and Venkatesh Kareenhalli Tags: Research Source Type: research
Role of the gut microbiota and innate immunity in polycystic ovary syndrome: Current updates and future prospects
This study reviewed recent research advances about the role of gut microbiota in PCOS. In order to provide basis for prevention and treatment of PCOS based on gut microbiota.PMID:38546608 | DOI:10.1111/jcmm.18258 (Source: J Cell Mol Med)
Source: J Cell Mol Med - March 28, 2024 Category: Molecular Biology Authors: Min Zhou Jing Yu Xuewei Li Zheng Ruan Shaohui Yu Source Type: research
Role of the gut microbiota and innate immunity in polycystic ovary syndrome: Current updates and future prospects
This study reviewed recent research advances about the role of gut microbiota in PCOS. In order to provide basis for prevention and treatment of PCOS based on gut microbiota.PMID:38546608 | DOI:10.1111/jcmm.18258 (Source: Molecular Medicine)
Source: Molecular Medicine - March 28, 2024 Category: Molecular Biology Authors: Min Zhou Jing Yu Xuewei Li Zheng Ruan Shaohui Yu Source Type: research
Role of the gut microbiota and innate immunity in polycystic ovary syndrome: Current updates and future prospects
This study reviewed recent research advances about the role of gut microbiota in PCOS. In order to provide basis for prevention and treatment of PCOS based on gut microbiota.PMID:38546608 | PMC:PMC10977384 | DOI:10.1111/jcmm.18258 (Source: J Cell Mol Med)
Source: J Cell Mol Med - March 28, 2024 Category: Molecular Biology Authors: Min Zhou Jing Yu Xuewei Li Zheng Ruan Shaohui Yu Source Type: research
Role of the gut microbiota and innate immunity in polycystic ovary syndrome: Current updates and future prospects
This study reviewed recent research advances about the role of gut microbiota in PCOS. In order to provide basis for prevention and treatment of PCOS based on gut microbiota.PMID:38546608 | PMC:PMC10977384 | DOI:10.1111/jcmm.18258 (Source: Molecular Medicine)
Source: Molecular Medicine - March 28, 2024 Category: Molecular Biology Authors: Min Zhou Jing Yu Xuewei Li Zheng Ruan Shaohui Yu Source Type: research
Role of the gut microbiota and innate immunity in polycystic ovary syndrome: Current updates and future prospects
This study reviewed recent research advances about the role of gut microbiota in PCOS. In order to provide basis for prevention and treatment of PCOS based on gut microbiota.PMID:38546608 | PMC:PMC10977384 | DOI:10.1111/jcmm.18258 (Source: J Cell Mol Med)
Source: J Cell Mol Med - March 28, 2024 Category: Molecular Biology Authors: Min Zhou Jing Yu Xuewei Li Zheng Ruan Shaohui Yu Source Type: research
Unraveling intestinal microbiota ’s dominance in polycystic ovary syndrome pathogenesis over vaginal microbiota
ConclusionTherefore, the response of the intestinal microbiota to PCOS is more significant than that of the vaginal microbiota. The intestinal microbiota is likely involved in the development of PCOS through its participation in hormonal regulation. (Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - March 28, 2024 Category: Microbiology Source Type: research
Body mass index is a good predictor of metabolic abnormalities in polycystic ovary syndrome
DiscussionBMI is a good predictor factor of metabolic changes in PCOS women at any age, and obesity is associated to the appearance of metabolic complications. Overweight and obese PCOS women should be addressed to perform a complete metabolic assessment. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - March 27, 2024 Category: Endocrinology Source Type: research
Exploring the molecular mechanisms by which per- and polyfluoroalkyl substances induce polycystic ovary syndrome through in silico toxicogenomic data mining
This study utilized toxicogenomics and comparative toxicogenomics databases to analyze data and investigate how PFAS mixtures may contribute to the development of PCOS. The results indicated that 74 genes are associated with both PFAS exposure and PCOS progression. Enrichment analysis suggested that cell cycle regulation and steroid hormone synthesis may be crucial pathways through which PFAS mixtures participate in the development of PCOS, involving important genes such as CCNB1 and SRD5A1. Furthermore, the study identified transcription factors (TFs) and miRNAs that may be involved in the onset and progression of PCOS, c...
Source: Ecotoxicology and Environmental Safety - March 27, 2024 Category: Environmental Health Authors: Xueming Xu Xiaoping Zhang Jiake Chen Xiushuai Du Yi Sun Liqin Zhan Wenxiang Wang Yuchen Li Source Type: research
Exploring the molecular mechanisms by which per- and polyfluoroalkyl substances induce polycystic ovary syndrome through in silico toxicogenomic data mining
This study utilized toxicogenomics and comparative toxicogenomics databases to analyze data and investigate how PFAS mixtures may contribute to the development of PCOS. The results indicated that 74 genes are associated with both PFAS exposure and PCOS progression. Enrichment analysis suggested that cell cycle regulation and steroid hormone synthesis may be crucial pathways through which PFAS mixtures participate in the development of PCOS, involving important genes such as CCNB1 and SRD5A1. Furthermore, the study identified transcription factors (TFs) and miRNAs that may be involved in the onset and progression of PCOS, c...
Source: Ecotoxicology and Environmental Safety - March 27, 2024 Category: Environmental Health Authors: Xueming Xu Xiaoping Zhang Jiake Chen Xiushuai Du Yi Sun Liqin Zhan Wenxiang Wang Yuchen Li Source Type: research
Relationship between serum apelin, visfatin levels, and body composition in Polycystic ovary syndrome patients
Polycystic ovary syndrome (PCOS) is an endocrine disorder that affects the female reproductive system. It is characterized by irregular ovulation, high levels of androgens, and multiple cysts on the ovaries. PCOS is a common condition among women of reproductive age [1]. Epidemiological findings indicate that the incidence of PCOS ranges from 3.7 % to 22.5 % [2]. The prevalence of PCOS in Chinese women is 7.8 %, affecting the reproductive health of approximately 24 million women [3]. In addition, PCOS is a systemic metabolic disorder that is often associated with obesity, insulin resistance, metabolic disorders, and...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - March 27, 2024 Category: OBGYN Authors: Dan Kuai, Qingtao Tang, Xiang wang, Qi Yan, Wenyan Tian, Huiying Zhang Tags: Full length article Source Type: research
