Asprosin: its function as a novel endocrine factor in metabolic-related diseases
ConclusionAsprosin is a multifaceted protein with tissue-specific roles in various physiological and pathological processes. Further research is needed to fully understand the mechanisms and potential of asprosin as a therapeutic target. These insights could provide new directions for treatments targeting metabolic-related diseases. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - April 3, 2024 Category: Endocrinology Source Type: research
Polycystic Ovary Syndrome, Insulin Resistance, and Cardiovascular Disease
AbstractPurpose of ReviewPolycystic ovary syndrome (PCOS) is a prevalent endocrine disorder in women of reproductive age. It has been associated with metabolic, reproductive, and psychiatric disorders. Despite its association with insulin resistance (IR) and cardiovascular disease (CVD) risk factors, the association between PCOS and CVD outcomes has been conflicting. This review reports the updated evidence between PCOS, insulin resistance, and CVD events.Recent FindingsIR is highly prevalent occurring in 50 to 95% of general and obese PCOS women. The etiology of PCOS involves IR and hyperandrogenism, which lead to CVD ris...
Source: Current Cardiology Reports - April 3, 2024 Category: Cardiology Source Type: research
Asprosin: its function as a novel endocrine factor in metabolic-related diseases
ConclusionAsprosin is a multifaceted protein with tissue-specific roles in various physiological and pathological processes. Further research is needed to fully understand the mechanisms and potential of asprosin as a therapeutic target. These insights could provide new directions for treatments targeting metabolic-related diseases. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - April 3, 2024 Category: Endocrinology Source Type: research
LncRNA SNHG12 promotes cell proliferation and inhibits apoptosis of granulosa cells in polycystic ovarian syndrome by sponging miR-129 and miR-125b
CONCLUSION: lncRNA SNHG12 might be a potential regulatory factor for the development of PCOS by sponging miR-129 and miR-125b in GCs.PMID:38566229 | DOI:10.1186/s13048-024-01392-6 (Source: Cell Research)
Source: Cell Research - April 2, 2024 Category: Cytology Authors: Feilan Xuan Ruiying Jin Weimei Zhou Yongju Ye Yuefang Ren Jiali Lu Aixue Chen Source Type: research
Lipoprotein alterations in endocrine disorders - a review of the recent developments in the field
Dyslipidemia is one of the most common disorders worldwide, which, if left untreated, results in a multitude of complications. Thus proper diagnostics, which includes identifying of secondary causes of dyslipidemia is crucial. Endocrine disorders are an important cause of secondary dyslipidemia. This paper aims to review the publications on lipoprotein alterations in endocrine disorders from the past two years and provide an overview of the recent discoveries in this dynamically developing and large field. Significant changes in lipoprotein serum concentrations are present in most endocrinological diseases and can be modif...
Source: Frontiers in Endocrinology - April 2, 2024 Category: Endocrinology Source Type: research
A Retrospective Review on Dysregulated Autophagy in Polycystic Ovary
Syndrome: From Pathogenesis to Therapeutic Strategies
In conclusion,
autophagy disorder is a key pathological mechanism in PCOS and is also a
potential target for drug development and design. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart,
GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - April 2, 2024 Category: Endocrinology Authors: Zhao, Yan Zhao, Xiaoxuan Jiang, Tianyue Xi, Hongyan Jiang, Yuepeng Feng, Xiaoling Tags: Review Source Type: research
Risk Factors for Incident Polycystic Ovary Syndrome Diagnosis
Journal of Women's Health, Ahead of Print. (Source: Journal of Women)
Source: Journal of Women - April 1, 2024 Category: OBGYN Authors: Jacob P. Christ Onchee Yu Brooke Barton Renate Schulze-Rath Jane Grafton David Cronkite Jennifer Covey Ann Kelley Erika Holden Jan Hilpert Frank Sacher Elizabeth Micks Susan D. Reed Source Type: research
104. Polycystic Ovary Syndrome and Mental Health Co-Morbidities in Adolescents
Mental health disorders (MHDs) have been associated with polycystic ovary syndrome (PCOS), but few studies have focused on the interplay between PCOS treatment modalities and MHDs in adolescents. This cohort study explored the prevalence of MHDs, the effect of hormonal treatment (HT) and 1,25-dihydroxyvitamin D3 (VitD) supplements on MHDs, biochemical characteristics of PCOS, and ultrasonographic measurements. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - April 1, 2024 Category: OBGYN Authors: Nora ONeill, Anna Lynn, Mark Zamani, Alexander Kuehne, Kathleen Miclette, Erin Rowe, Lauren Fussner, Alla Vash-Margita Source Type: research
93. Ovarian Hyperthecosis Resulting in Torsion in a Virilized Adolescent Female: A Case Report
Ovarian hyperthecosis (OH) results in severe hyperandrogenism or virilization, elevated levels of circulating androgens, and bilaterally enlarged ovaries. This clinical picture largely overlaps with polycystic ovarian syndrome (PCOS), the most commonly diagnosed condition in adolescent females who present with signs of androgen excess and oligomenorrhea. OH is primarily found in the postmenopausal population and is rare in adolescents; thus virilizing symptoms in an adolescent with a pelvic mass prompts concern for an androgen-secreting tumor. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - April 1, 2024 Category: OBGYN Authors: Aimee Morrison, Taryn Wassmer, Viktoriya Tulchinskaya, Sarah Swauger, Christine Pennesi Source Type: research
43. Eating attitudes, sleep quality, and self-esteem in adolescents diagnosed with polycystic ovary syndrome
The objective of this study was to evaluate the associations between PCOS and eating attitudes, self-esteem, and sleep quality in a sample of adolescents. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - April 1, 2024 Category: OBGYN Authors: Ozlem Ketenci Altikardesler, Ozlem Dural, Ipek Evruke, Hevra Ekin Ulusoy, Melike Zeynep Tugrul Aksakal, Firdevs Bas Source Type: research
29. Comparison of Incidence and Severity of Depression in Adolescents with PCOS in an Academic Pediatric Hospital before and during the COVID-19 Pandemic
Adolescents with polycystic ovarian syndrome (PCOS) are thought to be more susceptible to mental stress than their counterparts without PCOS. However, most of the literature describing the correlation between PCOS and depression is focused on adult women.Additionally, the COVID-19 pandemic resulted in a unique set of circumstances for adolescents that affected mental health, and has not yet been studied in adolescents with PCOS. The primary aim of this study is to analyze the differences in the incidence and severity of depression in adolescents with PCOS prior to and during the height of the COVID-19 pandemic from May 201...
Source: Journal of Pediatric and Adolescent Gynecology - April 1, 2024 Category: OBGYN Authors: Courtney Mascoe, Courtney Ford, Jessica Long, Ananya Krishnan, Veronica Gomez-Lobo, Sharyn Malcolm Source Type: research
7. A TikTok Take on PCOS
TikTok is a dominant social media platform with appeal to a relatively young consumer base. An estimated 1 in 4 of its users are under age 20 and up to 57% of users are female. The platform is commonly used by viewers to seek information regarding medical conditions. However, given its ease of content creation and algorithm to increase engagement, the platform is also rife with misinformation, which can cause harm to patients. The main objective of this study was to assess the content and reliability of TikTok videos made by medical professional creators versus other creators about polycystic ovarian syndrome (PCOS). (Sour...
Source: Journal of Pediatric and Adolescent Gynecology - April 1, 2024 Category: OBGYN Authors: Madison Labroo, Sydney Luu, Chelsea Kebodeaux, Yueyang Fei Source Type: research
Relationship between serum apelin, visfatin levels, and body composition in Polycystic Ovary Syndrome patients
CONCLUSIONS: Compared with healthy women, Patients with PCOS have an increased fat content in various parts of the body, reduced skeletal muscle content, and are often complicated by metabolic abnormalities. Serum visfatin and apelin correlated not only with obesity, fat mass, and fat distribution but also with muscle mass and distribution. It may be possible to reduce the long-term risk of metabolic disease in PCOS through the monitoring and management of the body composition in PCOS patients or to reflect the therapeutic effect of PCOS.PMID:38555852 | DOI:10.1016/j.ejogrb.2024.03.034 (Source: Reproductive Biology)
Source: Reproductive Biology - March 31, 2024 Category: Reproduction Medicine Authors: Dan Kuai Qingtao Tang Xiang Wang Qi Yan Wenyan Tian Huiying Zhang Source Type: research
Cytokine and chemokine profiles in women with endometriosis, polycystic ovary syndrome, and unexplained infertility
Cytokine. 2024 Mar 30;178:156588. doi: 10.1016/j.cyto.2024.156588. Online ahead of print.ABSTRACTNumerous factors (including immunological, congenital, hormonal, and morphological disorders) can lead to infertility. In this regard, 3 specific diseases associated with infertility are discussed in this review study (i.e., polycystic ovary syndrome [PCOS], endometriosis [EMS], and unexplained infertility [UI]). PCOS is a common endocrine disorder characterized by chronic low-grade inflammation, and EMS is a benign disease characterized by the presence of ectopic endometrial tissue. UI refers to couples who are unable to conce...
Source: Cytokine - March 31, 2024 Category: Molecular Biology Authors: Alireza Omidvar-Mehrabadi Fateme Ebrahimi Mehdi Shahbazi Mousa Mohammadnia-Afrouzi Source Type: research
Relationship between serum apelin, visfatin levels, and body composition in Polycystic Ovary Syndrome patients
CONCLUSIONS: Compared with healthy women, Patients with PCOS have an increased fat content in various parts of the body, reduced skeletal muscle content, and are often complicated by metabolic abnormalities. Serum visfatin and apelin correlated not only with obesity, fat mass, and fat distribution but also with muscle mass and distribution. It may be possible to reduce the long-term risk of metabolic disease in PCOS through the monitoring and management of the body composition in PCOS patients or to reflect the therapeutic effect of PCOS.PMID:38555852 | DOI:10.1016/j.ejogrb.2024.03.034 (Source: Reproductive Biology)
Source: Reproductive Biology - March 31, 2024 Category: Reproduction Medicine Authors: Dan Kuai Qingtao Tang Xiang Wang Qi Yan Wenyan Tian Huiying Zhang Source Type: research
