Interpretation of Melanocytic Lesions in the Digital Era vs Traditional Microscopy
This study of 87 pathologists compares the use of digital whole-slide imaging vs traditional microscopy in pathologists ’ ability to accurately interpret melanocytic lesions and reproduce correct diagnoses. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 15, 2018 Category: Dermatology Source Type: research

Self-reported Patient Motivations for Seeking Cosmetic Procedures
This multicenter observational study assesses the importance of self-reported factors that motivate patients to undergo minimally invasive cosmetic surgical procedures. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 15, 2018 Category: Dermatology Source Type: research

Resolution of Atypical Lichen Myxedematosus After Sofosbuvir-Velpatasvir Treatment for Hepatitis C
This case report describes a patient with lichen myxedematosus that resolved after sofosbuvir-velpatasvir treatment for hepatitis C infection. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 15, 2018 Category: Dermatology Source Type: research

Aprepitant for the Treatment of Pruritus in S ézary Syndrome
This randomized clinical trial assesses whether treatment with the neurokinin 1 receptor antagonist aprepitant decreases pruritus vs placebo in patients with S ézary syndrome. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 15, 2018 Category: Dermatology Source Type: research

A Case of Pigmented Longitudinal Melanonychia
A man in his 40s presented to the dermatology clinic for evaluation of a dark brown longitudinal pigment band covering his left second toenail; the lesion appeared 12 months prior, had been growing, and was asymptomatic. What is your diagnosis? (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 15, 2018 Category: Dermatology Source Type: research

Safety Risk of Dermatoscope Magnets in Patients With Cardiovascular Implanted Electronic Devices
This observational cross-sectional study assesses the magnets in 3 different dermatoscopes to determine their ability to disrupt the functionality of pacemakers, defibrillators, and other implanted devices in patients. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 15, 2018 Category: Dermatology Source Type: research

Avoiding and Managing Medicare Fraud and Abuse Investigations of Mohs Surgery
This Viewpoint discusses ways dermatologists can manage and avoid investigations by the US Department of Justice and the Centers for Medicare& Medicaid Services for alleged Medicare fraud and abuse related to Mohs surgery. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 8, 2018 Category: Dermatology Source Type: research

Association of Bullous Pemphigoid With Dipeptidyl-Peptidase 4 Inhibitors in Patients With Diabetes
This case-control study evaluates the association between use of dipeptidyl-peptidase 4 (DPP-4) inhibitors and development of bullous pemphigoid (BP) in patients with diabetes and characterizes those patients who develop DPP-4 inhibitor –associated BP. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 8, 2018 Category: Dermatology Source Type: research

Evaluation of a Brief Dermatologist-Delivered Intervention vs Usual Care on Sun Protection Behavior
This longitudinal controlled cohort study examines the association of a brief dermatologist-delivered intervention with patient satisfaction and sun protection behavior among adults receiving dermatology care. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 8, 2018 Category: Dermatology Source Type: research

Topical Crisaborole —A Potential Treatment for Recalcitrant Palmoplantar Psoriasis
This case report describes the use of topical crisaborole to treat previously treatment-refractory palmoplantar psoriasis (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 8, 2018 Category: Dermatology Source Type: research

A White Patch on the Tongue
An 80-year-old woman presented with an asymptomatic white patch affecting the tongue of 1 month ’s duration; she had a 15-year history of oral lichen planus managed with treatment. What is your diagnosis? (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 8, 2018 Category: Dermatology Source Type: research

JAMA Dermatology
Mission Statement:JAMA Dermatology publishes information concerning the skin, its diseases, and their treatment. Its mission is to explicate the structure and function of the skin and its diseases and the art of using this information to deliver optimal medical and surgical care to the patient. We attempt to enhance the understanding of cutaneous pathophysiology and improve the clinician ’s ability to diagnose and treat skin disorders. This journal has a particular interest in publishing clinical and laboratory studies that reveal new information pertinent to the interests and needs of the medical dermatologist, derm...
Source: JAMA Dermatology - August 1, 2018 Category: Dermatology Source Type: research

Friedrich Daniel von Recklinghausen
, MD, was one of the most prominent German pathologists of his time. His contributions resulted in the identification of several eponymous conditions, most notably von Recklinghausen disease, or neurofibromatosis type 1. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 1, 2018 Category: Dermatology Source Type: research

The Father of Spanish Dermatology
Jos é Eugenio de Olavide graduated with a degree in medicine and surgery in 1859 in his hometown of Madrid. After completing his studies, Olavide went to Paris and worked with several renowned physicians, including Armand Trousseau, Alfred Velpeau, and Jacques Maisonneuve. Olavide would attend grand ro unds presentations at the Hospital Saint-Louis, where he was exposed to famed dermatologists Pierre-Antoine-Ernest Bazin and Alfred Hardy. After spending 2 years in Paris, he returned to Madrid as a physician in the Hospital San Juan de Dios. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 1, 2018 Category: Dermatology Source Type: research

Distinguishing Mild, Moderate, and Severe Hidradenitis Suppurativa —Reply
In Reply We are grateful for the very constructive and positive feedback from Kokolakis and Sabat regarding our newly proposed Severity Assessment of Hidradenitis Suppurativa (SAHS) score. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 1, 2018 Category: Dermatology Source Type: research

August 2018 Issue Highlights
(Source: JAMA Dermatology)
Source: JAMA Dermatology - August 1, 2018 Category: Dermatology Source Type: research

Machine Learning and Health Care Disparities in Dermatology
This viewpoint discusses the limitations of machine learning in diagnostics involving skin of color. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 1, 2018 Category: Dermatology Source Type: research

Hair Regrowth Outcomes of Contact Immunotherapy for Patients With Alopecia Areata
This systematic review and meta-analysis uses standardized criteria and prognostic factors to examine the clinical hair regrowth outcomes of contact immunotherapy with diphenylcyclopropenone or squaric acid dibutyl ester for patients with alopecia areata. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 1, 2018 Category: Dermatology Source Type: research

Comparison of Course and Outcome for Patients With Disseminated or Localized Lyme Borreliosis
This cohort study compares the development and treatment outcome of disease among European patients with Lyme borreliosis manifested as either multiple erythema migrans or as erythema migrans as well as controls without a history of the disease. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 1, 2018 Category: Dermatology Source Type: research

Association of Low SES With Hidradenitis Suppurativa
This cohort analysis evaluates the association of low socioeconomic status with hidradenitis suppurativa among patients in the United States. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 1, 2018 Category: Dermatology Source Type: research

An Atypical Figurate Erythema With Seasonal Recurrences
A woman had a large annular erythematous plaque on her back that had centrifugally expanded. She had mild pruritus that had not responded to antihistamine therapy or topical steroids and reported a 20-year history of the plaques recurring every summer and resolving by autumn. What is your diagnosis? (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 1, 2018 Category: Dermatology Source Type: research

Association Between Severe Acute Contact Dermatitis Due to N sativa Oil and Epidermal Apoptosis
This case series describes the clinical and histologic features of severe acute contact dermatitis due toNigella sativa oil and investigates the components responsible for such eruptions. (Source: JAMA Dermatology)
Source: JAMA Dermatology - August 1, 2018 Category: Dermatology Source Type: research

Increasing Minority Representation in the Dermatology Department
This Viewpoint reviews Johns Hopkins ’ successful experience in increasing the number of faculty physicians in dermatology from groups underrepresented in medicine and suggests steps that other institutions can take to replicate this success. (Source: JAMA Dermatology)
Source: JAMA Dermatology - July 25, 2018 Category: Dermatology Source Type: research

Incidence of Endemic Human Cutaneous Leishmaniasis in the United States
This observational study reviews cases of endemic human leishmaniasis occurring in the United States, mostly in Texas, over a 10-year period. (Source: JAMA Dermatology)
Source: JAMA Dermatology - July 25, 2018 Category: Dermatology Source Type: research

Association Between Mediterranean Anti-inflammatory Dietary Profile and Severity of Psoriasis
This cohort study uses a self-completed questionnaire by respondents in the French NutriNet-Sant é study to evaluate the association between a Mediterranean anti-inflammatory dietary profile and the severity of psoriasis. (Source: JAMA Dermatology)
Source: JAMA Dermatology - July 25, 2018 Category: Dermatology Source Type: research

Performance of Dermatology Physician Assistants —Reply
In Reply We thank Marghoob et al for the opportunity to address their concerns regarding our study. Number needed to biopsy (NNB) (or excise) is a well-established measure consistent with prior publications, including studies by Marghoob and colleagues. While NNB can vary with disease prevalence, patients in both cohorts in our study had similar rates of keratinocyte carcinomas and invasive melanomas. Patients were also similarly distributed by age and sex, and our NNB findings remained consistent when patients with a melanoma history were excluded. (Source: JAMA Dermatology)
Source: JAMA Dermatology - July 25, 2018 Category: Dermatology Source Type: research

RCM and En Face Histopathologic Correlation of the Dermoscopic “Circle Within a Circle” in LM
This case report describes a process by which the dermoscopic “circle within a circle” feature can be correlated with findings of reflectance confocal microscopic (RCM) and en face histopathologic findings from a lentigo maligna lesion. (Source: JAMA Dermatology)
Source: JAMA Dermatology - July 25, 2018 Category: Dermatology Source Type: research

Performance of Dermatology Physician Assistants
To the Editor In a recent issue ofJAMA Dermatology, Anderson et al aimed to compare skin cancer diagnostic accuracy of physician assistants (PAs) with that of dermatologists (MDs) and used the number needed to biopsy as the main outcome measure. (Source: JAMA Dermatology)
Source: JAMA Dermatology - July 25, 2018 Category: Dermatology Source Type: research

Facial-Aging App Availability in Waiting Rooms as a Potential Opportunity for Skin Cancer Prevention
This survey study explores whether a single exposure of adult patients in a waiting room to an app that approximates facial UV damage may lead to altered UV protection behavior. (Source: JAMA Dermatology)
Source: JAMA Dermatology - July 25, 2018 Category: Dermatology Source Type: research

Violaceous Patches in the Axilla
A man in his 40s presented with dark red, circular lesions in his right axilla without pain, blisters, or other symptoms; after resolution with a topical cream, similar lesions appeared in his left axilla and inguinal folds 5 months later. What is your diagnosis? (Source: JAMA Dermatology)
Source: JAMA Dermatology - July 25, 2018 Category: Dermatology Source Type: research

Characteristics and Skin Cancer Risk Behaviors of US Adult Sunless Tanners
This secondary analysis of a cross-sectional study using data from the 2015 National Health Interview Survey assesses the demographic characteristics and skin cancer risk behaviors of US adults who are sunless tanners. (Source: JAMA Dermatology)
Source: JAMA Dermatology - July 25, 2018 Category: Dermatology Source Type: research

Scabies —An Ancient Disease With Unanswered Questions in Modern Times
This Viewpoint discusses the global disease burden of scabies, as well as its diagnosis and treatment. (Source: JAMA Dermatology)
Source: JAMA Dermatology - July 18, 2018 Category: Dermatology Source Type: research

Effect of Stress Ball Use or Hand-holding on Anxiety During Skin Cancer Excision
This randomized clinical trial examines the effects of hand-holding vs stress ball use compared with usual care on anxiety in patients undergoing excisional removal of nonmelanoma skin cancer of the head or neck with local anesthesia. (Source: JAMA Dermatology)
Source: JAMA Dermatology - July 18, 2018 Category: Dermatology Source Type: research

Sunscreen Use and Melanoma Risk Among Young Australian Adults
This population-based, case-control family study of data collected for the Australian Melanoma Family Study assesses the association of sunscreen use in childhood and early adulthood with the risk of cutaneous melanoma before age 40 years. (Source: JAMA Dermatology)
Source: JAMA Dermatology - July 18, 2018 Category: Dermatology Source Type: research

A Comparison of Tanning Habits Among Gym Tanners and Other Tanners
This survey study evaluates the incidence of tanning in adults who use indoor gyms. (Source: JAMA Dermatology)
Source: JAMA Dermatology - July 18, 2018 Category: Dermatology Source Type: research

Spiky Skin in a Renal Transplant Recipient
A woman in her 70s with a cadaveric renal transplant presented with a 1-year history of a facial cutaneous eruption and mildly pruritic lesions, initially affecting malar cheeks and eyebrows and subsequently spreading to involve the nose, chin, upper trunk, and extremities. What is your diagnosis? (Source: JAMA Dermatology)
Source: JAMA Dermatology - July 18, 2018 Category: Dermatology Source Type: research

Timing of Onset of Adverse Cutaneous Reactions Associated With PD-1 Inhibitor Therapy
This observational study assesses the timing of onset of cutaneous reactions after initiation of programmed cell death protein 1 therapy in patients with metastatic melanoma or carcinoma. (Source: JAMA Dermatology)
Source: JAMA Dermatology - July 18, 2018 Category: Dermatology Source Type: research

Myths, Truths, and Clinical Relevance of Comedogenicity Product Labeling
This Viewpoint evaluates the meaning of the noncomedogenic label and the need for an objective assay for assessment of facial products. (Source: JAMA Dermatology)
Source: JAMA Dermatology - July 11, 2018 Category: Dermatology Source Type: research

Dermatology Procedures Billed by Advanced Practice Professionals, 2012-2015
This longitudinal study uses Medicare data from 2012 through 2015 to review the trends in scope and volume of dermatology procedures performed by advanced practice professionals such as nurse practitioners and physician assistants. (Source: JAMA Dermatology)
Source: JAMA Dermatology - July 11, 2018 Category: Dermatology Source Type: research

Economic Analysis of a Noninvasive Molecular Pathologic Assay for Pigmented Skin Lesions
This economic analysis assesses the costs of use of the pigmented lesion assay vs visual and histopathologic assessment in model inputs of patients with primary pigmented lesions suggestive of melanoma. (Source: JAMA Dermatology)
Source: JAMA Dermatology - July 11, 2018 Category: Dermatology Source Type: research

Association of Lichen Planopilaris With Dyslipidemia
This cohort study evaluates the association between lichen planopilaris, hyperlipidemia, and metabolic syndrome. (Source: JAMA Dermatology)
Source: JAMA Dermatology - July 11, 2018 Category: Dermatology Source Type: research

Skin Cancer Detection In Vivo With Reflectance Confocal Microscopy Performed by a Novice Reader
This study evaluates the learning curve, diagnostic accuracy, and challenges for a novice reader of reflectance confocal microscopy for determining a diagnosis of skin cancer. (Source: JAMA Dermatology)
Source: JAMA Dermatology - July 11, 2018 Category: Dermatology Source Type: research

An Atrophic and Spiny Eruption of the Palms
A woman presented with a pruritic and burning hyperpigmented eruption on the bilateral palms; examination revealed well-marginated brown atrophic patches on the bilateral palms extending focally onto the volar aspect of the wrist and surmounted by spiny keratotic pits in the palmar creases. What is your diagnosis? (Source: JAMA Dermatology)
Source: JAMA Dermatology - July 11, 2018 Category: Dermatology Source Type: research

Prescription to OTC Switch of Metronidazole and Azelaic Acid for Rosacea
This Viewpoint considers the advantages and disadvantages of topical treatments for rosacea, specifically metronidazole and azelaic acid, undergoing review to switch from prescription to over-the-counter availability. (Source: JAMA Dermatology)
Source: JAMA Dermatology - July 3, 2018 Category: Dermatology Source Type: research

Association of Inadequately Controlled Disease With Patient-Reported Disease Burden in Atopic Dermatitis
This cross-sectional study examines the association of atopic dermatitis severity and disease control with the patient-reported disease burden in clinical practice. (Source: JAMA Dermatology)
Source: JAMA Dermatology - July 3, 2018 Category: Dermatology Source Type: research

Underuse of the Sentinel Lymph Node Biopsy for High-Risk SCC of the Skin —Reply
In Reply We read with interest the response by Glazer et al regarding our study on the underuse of sentinel lymph node biopsy (SLNB) for high-risk cutaneous squamous cell carcinoma (cSCC) and noted several important inquiries and comments. (Source: JAMA Dermatology)
Source: JAMA Dermatology - July 3, 2018 Category: Dermatology Source Type: research

Dupilumab Treatment of Very Severe Refractory Atopic Hand Eczema
This case report describes the use of dupilumab to treat a patient with very severe refractory atopic hand eczema. (Source: JAMA Dermatology)
Source: JAMA Dermatology - July 3, 2018 Category: Dermatology Source Type: research

Onychomadesis Following a Fish Pedicure
This case reports describe the occurrence of onychomadesis in a patient following a fish pedicure. (Source: JAMA Dermatology)
Source: JAMA Dermatology - July 3, 2018 Category: Dermatology Source Type: research

Underuse of the Sentinel Lymph Node Biopsy for High-Risk SCC of the Skin
To the Editor We read with interest the article by Ahadiat et al regarding the potential underuse of sentinel lymph node biopsy (SLNB) in patients with high-risk cutaneous squamous cell carcinoma (cSCC). Although SLNB may be underused in these patients, we have some inquiries regarding the research methods and generalizability of the data. (Source: JAMA Dermatology)
Source: JAMA Dermatology - July 3, 2018 Category: Dermatology Source Type: research

The Future of JAMA Dermatology
I am deeply humbled to be selected to serve as Editor in Chief ofJAMA Dermatology. The fundamental role of an editor in chief is to review, select, and publish the articles that best help clinicians practice more safely and effectively. The opportunity to illuminate the aspects of our field that deserve spotlight is a task both daunting and delightful. I am committed to do a deep dive into dermatology to identify what is most significant, what is most fascinating, what is most problematic, and to find opportunities to improve and elevate the practice of dermatologists. My ultimate goal is to ensure that dermatologists deli...
Source: JAMA Dermatology - July 3, 2018 Category: Dermatology Source Type: research