Obstetric perineal tears: risk factors, wound infection and dehiscence: a prospective cohort study
ConclusionsInstrumental delivery and high birth weight increased the risk of perineal tears. Severe obesity and episiotomy increased the risk of perineal wound complications. More focus on these women may be warranted postpartum. The use of prophylactic antibiotics among women in high risk of wound complications should be further investigated in interventional studies. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - April 19, 2019 Category: OBGYN Source Type: research

The effect of luteal GnRH antagonist on moderate and severe early ovarian hyperstimulation syndrome during in vitro fertilization treatment: a prospective cohort study
ConclusionCetrorelix effectively reduces the incidence of early moderate and severe OHSS in high-risk women and decreases serum VEGF levels. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - April 19, 2019 Category: OBGYN Source Type: research

Prognostic factors and oncological outcomes of ovarian yolk sac tumors: a retrospective multicentric analysis of 99 cases
ConclusionsOur results demonstrate the significance of achieving no visible residual disease in patients with ovarian YST. Fertility-sparing approach for patients with no visible residual disease affected neither DFS nor OS. Although high lymphatic involvement rate was detected, the benefit of LND could not be demonstrated. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - April 13, 2019 Category: OBGYN Source Type: research

The ENZIAN score as a preoperative MRI-based classification instrument for deep infiltrating endometriosis
ConclusionsThe MRI-based ENZIAN score correlates well with the intraoperative findings, enabling a better planning of the surgical procedure for patients and physicians. However, considerable difficulty and a poorer comparability result from the variations in sequences used in the detection of this multifaceted disease. Therefore, a standardization of MRI protocols used in the detection of DIE will be a crucial step towards increased diagnostic validity and the ENZIAN score may be used as an anatomical land map and valuable communication tool between radiologists and gynecologists. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - April 12, 2019 Category: OBGYN Source Type: research

A new approach to prevent ischemia/reperfusion injury in a rat model: remote ischemic conditioning
AbstractPurposeTo evaluate the effect of remote ischemic conditioning (RIC) on ovarian ischemia/reperfusion injury in a rat model.MethodsA total of 36 Wistar albino rats with a body weight of 220 –250 g were used for this study. Right adnexal torsion was performed for 180 min, and at the end of the period, the adnex was released and the abdomen was reclosed for 180 min for reperfusion. Torsion and detorsion procedures were applied to all rats except group 1 (sham, control). The right lo wer extremity was tied to perform remote tissue ischemia in groups 3, 4, 5, and 6. The goal of the procedure, which w...
Source: Archives of Gynecology and Obstetrics - April 12, 2019 Category: OBGYN Source Type: research

Comparing birth experience and birth outcome of vaginal births between induced and spontaneous onset of labour: a prospective study
DiscussionSuccessful labour induction resulting in a vaginal birth did not negatively influence birth and fetal outcomes and only partly affected the women ’s birth experience. The negative impact of labour induction on the dimensionsPerceived Safety andParticipation should sensitize midwives in order to provide optimal support. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - April 11, 2019 Category: OBGYN Source Type: research

The effect of localization and histological verification of endometrial polyps on infertility
ConclusionsPolypectomy improved the conception rate in the subsequent year regardless of the intrauterine localization and the method of its surgical removal. Therefore, we can conclude that polypectomy should be considered in infertile women. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - April 11, 2019 Category: OBGYN Source Type: research

Applicability of WHO Maternal Severity Score (MSS) and Maternal Severity Index (MSI) Model to predict the maternal outcome in near miss obstetric patients: a prospective observational study
AbstractObjectiveTo assess the applicability of WHO Maternal Severity Score (MSS) and Maternal Severity Index (MSI) Model in near miss (NM) obstetric patientsMethodsIt was a prospective observational study conducted at a tertiary health care center from July 2015 to Feb 2016. All patients fulfilling one or more WHO NM criteria were included. MSS and MSI were calculated for all NM patients on admission. They were then followed up till the final outcome (NM or death). Each NM parameter, system-wise MSS, total MSS and MSI were then associated with the final outcome.ResultsOf 4822 patients, 1739 had potentially life-threatenin...
Source: Archives of Gynecology and Obstetrics - April 11, 2019 Category: OBGYN Source Type: research

A predictive formula for selecting individual FSH starting dose based on ovarian reserve markers in IVF/ICSI cycles
ConclusionsIn the present study we demonstrated that the individualized FSH starting dose may be calculated on the basis of a woman ’s age, AMH and AFC. The formula model might be a useful, immediate, and easily applicable tool for clinicians to predict the tailored starting dose of FSH during their daily clinical practice. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - April 11, 2019 Category: OBGYN Source Type: research

Endometrial human chorionic gonadotropin (hCG) expression is a marker for adequate secretory transformation of the endometrium
ConclusionsOur results suggest endometrial hCG as a possible diagnostic parameter characterizing the endometrial secretory transformation and, thus, possibly also its implantation capability. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - April 6, 2019 Category: OBGYN Source Type: research

Reply to comments on “Risk factors, microbiology and management of infected lymphocyst after lymphadenectomy for gynecologic malignancies”
(Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - April 6, 2019 Category: OBGYN Source Type: research

Comparison of two “a priori” risk assessment algorithms for preeclampsia in Italy: a prospective multicenter study
AbstractPurposeTo compare the performance of the algorithms proposed by the Fetal Medicine Foundation in 2012 and BCNatal in 2013 in an Italian population.MethodsA multicentric prospective study was carried out which included pregnancies at 11 –13 weeks’ gestation from Jan 2014 through May 2017. Two previously published algorithms were used for the calculation of the “a priori” risk of preeclampsia (based on risk factors from medical history) in each individual.ResultsIn a study population of 11,632 cases, 67 (0.6%) developed early preeclampsia and 211 (1.8%) developed late preeclampsia. The de...
Source: Archives of Gynecology and Obstetrics - April 5, 2019 Category: OBGYN Source Type: research

An observation study of the emergency intervention in placenta accreta spectrum
This study explored the probability and outcome of delivery in women with placenta accreta spectrum (PAS) according to gestational age at delivery.MethodsA retrospective cohort study among women with PAS who had cesarean section was conducted. The gestational week (gw) of delivery and estimated blood loss (EBL) were recorded. The proportion of urgent delivery beyond 32 gw and EBL in women with or without antepartum suspected diagnosis of placenta accreta was compared.ResultsTotally, 180 women with PAS were enrolled. Of these, 54 (30.0%, 95% CI 23.8 –37.1%) were delivered by urgent cesarean delivery and 126 (70.0%, 95...
Source: Archives of Gynecology and Obstetrics - April 5, 2019 Category: OBGYN Source Type: research

Long-term effects of prenatal exposure to metformin on the health of children based on follow-up studies of randomized controlled trials: a systematic review and meta-analysis
ConclusionIncreased offspring weight was more observed in children prenatal exposure to metformin. Heathcare providers and patients should be aware that metformin is increasingly prescribed in pregnancy based on the relatively limited evidences but nonetheless encouraging long-term offspring data are available. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - April 5, 2019 Category: OBGYN Source Type: research

Molecular expression characteristics confirm the malignancy concealed by morphological alterations in endometrial cancer after fertility-preserving treatment
ConclusionThe morphologic normalization of patients with EC after FPT may not be accompanied by the absence of tumor malignancy, and β-catenin may serve as a biomarker for the response to FPT. These results may contribute to a better understanding of the malignant transformation of EC after FPT and the optimization of treatment strategies for young patients with birth plans. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - April 5, 2019 Category: OBGYN Source Type: research

An update on the role of Atopobium vaginae in bacterial vaginosis: what to consider when choosing a treatment? A mini review
ConclusionCurrent scientific data demonstrate that dequalinium chloride (Fluomycin®) is one of the valid therapeutic options for BV treatment, since it displays a broad antimicrobial spectrum against relevant vaginal pathogens, especially against G. vaginalis and A. vaginae, without having safety concerns. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - April 5, 2019 Category: OBGYN Source Type: research

Prevalence of oral HPV infection in cervical HPV positive women and their sexual partners
ConclusionThe data demonstrate that the overall risk of an oral HPV infection is low. HPV transmission to the oropharynx by autoinoculation or oral-genital contact constitute a rare and unlikely event. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - April 5, 2019 Category: OBGYN Source Type: research

Tumor-targeting Salmonella typhimurium A1-R overcomes nab-paclitaxel resistance in a cervical cancer PDOX mouse model
AbstractPurposeCervical cancer is a recalcitrant disease. To help overcome this problem, we previously established a patient-derived orthotopic xenograft (PDOX) model of cervical cancer. In the previous study, we found the tumor to be resistant to nab-paclitaxal (nab-PTX). We also previously developed the tumor-targeting bacteriaSalmonella typhimurium A1-R (S. typhimurium A1-R). The aim of the present study was to investigate the efficacy ofS. typhimurium A1-R to overcome nab-PTX resistance in the cervical cancer PDOX model.MethodsCervical-cancer tumor fragments were implanted orthotopically into the neck of the uterus of ...
Source: Archives of Gynecology and Obstetrics - April 5, 2019 Category: OBGYN Source Type: research

Pilot study: placental biomarker predictive capability (sFlt-1, PlGF and their ratio) of postpartum maternal outcome
ConclusionSerum concentrations of sFlt-1 and PlGF or their ratio in our study cohort did not completely predict the occurrence of postpartum preeclampsia. Yet, postpartum higher serum PlGF level was associated with postpartum elevation of the systolic blood pressure. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - April 5, 2019 Category: OBGYN Source Type: research

Laparoscopic excision of deeply infiltrating endometriosis: a prospective observational study assessing perioperative complications in 244 patients
ConclusionsA combination of different laparoscopic surgical techniques to completely excise all visible DIE, within the context of a tertiary referral center offering multi-disciplinary approach, produces safe outcomes with low complication rates. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - April 5, 2019 Category: OBGYN Source Type: research

Current practice and physicians ’ opinion about preoperative hair removal as a part of ERAS pathway implementation in gynecology and gynecology–oncology: a NOGGO-AGO survey of 148 gynecological departments in Germany
ConclusionPHR in gynecological departments in Germany is performed very heterogeneously and SOPs are often not based on guidelines and ERAS principles. Around one-third of the German gynecological clinics keep strictly to the guidelines. The awareness on PHR and SSI among junior doctors is very low. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - April 5, 2019 Category: OBGYN Source Type: research

Calprotectin in pregnancy and pregnancy-associated diseases: a systematic review and prospective cohort study
ConclusionCalprotectin concentrations in amnion fluid and stools serve as potential indicators of inflammatory states during pregnancy. Urinary calprotectin concentrations are continuously high during pregnancy and show no significant variations between trimesters 1 –3 and post-partum. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - April 5, 2019 Category: OBGYN Source Type: research

What uro-gynecologists should know about sacral neuromodulation (SNM) for the treatment of refractory overactive bladder
ConclusionsSNM is a successful and recommended second-line treatment of OAB. Sacral neurostimulators should preferably be implanted in SNM-centers because complications and the frequency of revisions are significantly reduced with increasing experience of the surgeon. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - April 2, 2019 Category: OBGYN Source Type: research

Novel circular RNA expression in the cumulus cells of patients with polycystic ovary syndrome
This study aimed to detect the novel expression of circRNAs in the cumulus cells (CCs) of polycystic ovary syndrome (PCOS) patients and their potential significance in the pathogenesis of PCOS.MethodscircRNAs in the CCs from 6 PCOS patients and 6 normal control individuals were collected for microarray analysis, and an independent cohort study including 25 PCOS patients and 25 normal control individuals was conducted to validate the circRNA microarray results using quantitative real-time polymerase chain reaction (qRT-PCR). Spearman ’s rank correlation and receiver operating characteristic (ROC) were performed to del...
Source: Archives of Gynecology and Obstetrics - April 2, 2019 Category: OBGYN Source Type: research

Blockade pf CD73/adenosine axis improves the therapeutic efficacy of docetaxel in epithelial ovarian cancer
ConclusionBlocking CD73/adenosine pathway could reverse the immunosuppression caused by DTXL, and a combination of DTXL with CD73 inhibitor or anti-CD73 antibody would be a more effective and promising therapy for EOC. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - April 2, 2019 Category: OBGYN Source Type: research

Disease activity and thromboembolic events in women with systemic lupus erythematosus with and without anti-phospholipid syndrome: users of the 52-mg levonorgestrel-releasing intrauterine system
ConclusionsOur results, although restricted, provide information to policymakers and health professionals that the use of a 52  mg LNG-IUS over a 5-year median did not increase disease activity or damage index scores among women with SLE, with and without APS. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - April 2, 2019 Category: OBGYN Source Type: research

The impact of sperm DNA fragmentation on ICSI outcome in cases of donated oocytes
AbstractPurposeThe aim of this study is to evaluate the sperm DNA fragmentation index (DFI) in oocyte donation cycles and correlate it with the sperm parameters, the male characteristics, the embryo quality and the outcome of intracytoplasmic sperm injection (ICSI).MethodsA total of 150 couples participating in an oocyte donation program were included in the study. Sperm samples were assessed by conventional sperm analysis. DFI was evaluated using the Halosperm kit, a sperm chromatin dispersion test (SCD).ResultsThe relations between DNA damage and epidemiological male factors (age, height, weight), standard semen paramete...
Source: Archives of Gynecology and Obstetrics - April 2, 2019 Category: OBGYN Source Type: research

Uterus transplantation: advantages and disadvantages of a deceased donor
(Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - April 2, 2019 Category: OBGYN Source Type: research

The effectiveness of inositol and metformin on infertile polycystic ovary syndrome women with resistant to letrozole
ConclusionThe addition of inositol and metformin to the treatment of infertile PCOS women with letrozole resistance improves the ovarian function; however, it is not significant. Of note, inositol was more effective than metformin in patients with normal BMI.IRCT registration numberIRCT2017070234845N1 (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - March 26, 2019 Category: OBGYN Source Type: research

Incisional hernias following open gynecological surgery: a population-based study
AbstractIntroductionIncisional hernia is a common and costly complication following abdominal surgery. The incidence of incisional hernia after gynecological surgery is not as well studied as that after general surgery.Materials and methodsThe Swedish National Quality Register for Gynecological Surgery (GynOp) collects preoperative, intraoperative, and postoperative information regarding gynecological surgery. Data were extracted from 2006 to 2014. The National Patient Register (NPR) contains physicians ’ data from both public and private hospitals. Univariate and multivariate Cox proportional hazard analyzes were pe...
Source: Archives of Gynecology and Obstetrics - March 25, 2019 Category: OBGYN Source Type: research

Laparoscopic pectopexy: a follow-up cyclic biomechanical analysis determining time to functional stability
ConclusionThis trial showed in an in vitro cyclic testing of the pectopexy method that functional stability may be achieved after no more than 19.1 cycles of load exposure. When remaining within the established load envelope of below 25  N, patients do not need to fear global fixation failure. Testing did demonstrate differences in non-embalmed and embalmed cadaver testing. Embalmed cadaver testing tends to underestimate time to steady state by 26.3%. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - March 23, 2019 Category: OBGYN Source Type: research

Wnt signaling pathway in early- and late-onset preeclampsia: evaluation with Dickkopf-1 and R-Spondin-3 glycoproteins
ConclusionThe increased serum level of Dickkopf-1 might be associated with the process of pathogenesis of early-onset PE. Further studies would elucidate their exact roles in the pathogenesis of PE. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - March 23, 2019 Category: OBGYN Source Type: research

Splenic artery blood flow as a potential marker for materno-fetal transmission of a primary CMV infection
ConclusionThe PSV may be a marker for maternal –fetal CMV transmission following a first-trimester maternal infection. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - March 23, 2019 Category: OBGYN Source Type: research

Reply to the comments on & quot;Modified hysterectomy for placenta increta and percreta: modifications of what? & quot;
(Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - March 20, 2019 Category: OBGYN Source Type: research

Recurrent serous borderline ovarian tumour
(Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - March 20, 2019 Category: OBGYN Source Type: research

Effects of clarithromycin on inflammatory markers and clinical manifestations in postsurgical follow-up of patients with endometriosis: a double-blinded randomized placebo-controlled clinical trial
AbstractPurpose Studies showed anti-inflammatory and immunomodulatory effects of macrolide antibiotics such as clarithromycin in endometriosis. Therefore, the present study aims to investigate the therapeutic efficacy of clarithromycin in patients with endometriosis.MethodsThis was a double-blinded randomized placebo-controlled trial conducted on endometriotic women during March 2016 –2017 in Dena Hospital, Shiraz, Iran. Immediately after surgery, the patients were randomly divided into clarithromycin (real) (n = 120) and placebo group (n = 169). The real group received 500 mg of cl...
Source: Archives of Gynecology and Obstetrics - March 19, 2019 Category: OBGYN Source Type: research

Neurovascular and lymphatic vessels distribution in uterine ligaments based on a 3D reconstruction of histological study: to determine the optimal plane for nerve-sparing radical hysterectomy
ConclusionCAAD is an effective anatomical method to study the precise distribution of neurovascular and lymphatic vessels in uterine ligaments. It can present detailed anatomical information about female pelvic autonomic innervation and the spatial relationship between nerves and vessels and may provide a better understanding of nerve-sparing radical hysterectomy. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - March 14, 2019 Category: OBGYN Source Type: research

Screening for blood born viruses in assisted reproduction: is annual testing necessary?
ConclusionsPrimary infection with HBV, HCV, or HIV is an extremely rare event among Israeli infertile patients, and the risk for seroconversion in this population is practically nil. Annual screening of both partners leads to substantial costs and appears to be futile. Our results question the current practice and support increasing the interval between screening tests in low-risk populations. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - March 14, 2019 Category: OBGYN Source Type: research

Can myometrial thickness/cervical length ratio predict preterm delivery in singleton pregnancies with threatened preterm labor? A prospective study
AbstractObjectiveTo investigate whether myometrial thickness (MT) to cervical length (CL) ratio could be used in the prediction of preterm birth (PTB) in singleton pregnancies presented with threatened preterm labor (TPL).MethodsAfter 48  h of successful tocolysis, MT was measured transabdominally from the fundal, mid-anterior walls and the lower uterine segment (LUS) in 46 pregnancies presented with TPL. MT measurements were divided into CL, individually. The main outcome was PTB before 37 weeks of gestation.ResultsThe patients were divided into two groups as women delivered  ≥ 37 weeks (38...
Source: Archives of Gynecology and Obstetrics - March 14, 2019 Category: OBGYN Source Type: research

Endoscopic surgery: talent or training?
This study proves whether the subjective impression of the laparoscopic trainer is verifiable and which factors influence extreme talent.Methods21 medical students of the eighth term of the University of Witten-Herdecke participated in the study. On their first course day, students got instructed in suturing and knot technique. They were then required to tie a maximum of five knots within 2  h. After a week, students repeated this procedure. Time used for tying knots was stopped.ResultsRegarding the time students used for their first knots, great differences were provable (7 –8 min, average 23 min). Ho...
Source: Archives of Gynecology and Obstetrics - March 14, 2019 Category: OBGYN Source Type: research

Efficacy of a collagen-fibrin sealant patch (TachoSil ®) as adjuvant treatment in the inguinofemoral lymphadenectomy for vulvar cancer: a double-blind randomized-controlled trial
ConclusionApplication of TachoSil ® does not seem to improve postoperative lymphorrhagia nor to reduce the incidence of postoperative complications in patients undergoing inguinofemoral lymphadenectomy for vulvar cancer. Considering this point, it would be useful to identify additional strategies in inguinofemoral dissection for th e prevention of these complications. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - March 11, 2019 Category: OBGYN Source Type: research

Modified hysterectomy for placenta increta and percreta: modifications of what?
(Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - March 11, 2019 Category: OBGYN Source Type: research

Spatulas for entrapment of the after-coming head during vaginal breech delivery
ConclusionIn compliance with obstetrical mechanics, spatulas should be considered as an effective instrument during EAH with maternal and foetal safety. This is the first cohort describing the use of an instrument to manage EAH during vaginal breech delivery, while knowledge and mastery of this technique are essential to manage this situation. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - March 9, 2019 Category: OBGYN Source Type: research

Different progestin-primed ovarian stimulation protocols in infertile women undergoing in vitro fertilization/intracytoplasmic sperm injection: an analysis of 1188 cycles
AbstractPurposeTo evaluate the efficacy in suppressing the premature LH surge, embryo quality and pregnancy outcomes of progestin-primed ovarian stimulation (PPOS) protocols using medroxyprogesterone acetate versus utrogestan in women of all ages undergoing in vitro fertilization or intracytoplasmic sperm injection.Methods1188 patients were enrolled in the retrospective study, of which 1002 patients were treated with medroxyprogesterone acetate (M group) and recombinant follicle-stimulating hormone (r-FSH)simultaneously from day 3 of the cycle until trigger day, while 186 patients were treated with utrogestan (U group) and...
Source: Archives of Gynecology and Obstetrics - March 9, 2019 Category: OBGYN Source Type: research

Analysis of the reproductive outcomes and the size of the unicornuate uterus measured by magnetic resonance imaging and their relationship
AbstractPurposeTo evaluate the relationship between the uterine size measured by pelvic magnetic resonance and reproductive outcome in women with a unicornuate uterus.MethodsThis was a retrospective study including 140 patients affiliated with unicornuate uterus diagnosed by the pelvic MR prior to their first pregnancy in the Obstetrics and Gynecology Hospital of Fudan University from April 2010 to December 2017. All the length of the unicornuate uterus were re-measured and recorded by skilled radiologists during the study period. We divided all the 140 participants with complete pelvic MR imaging into four groups by the b...
Source: Archives of Gynecology and Obstetrics - March 8, 2019 Category: OBGYN Source Type: research

Compare two different usages of FRD for detecting high-grade cervical lesions and invasive cancer
ConclusionCompared with TCT and HPV testing, two usages of FRD methods have compatible sensitivity and high specificity to detect high-grade cervical lesions and invasive cancer. FRD direct staining may be comfortable for routine cervical cancer screening (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - March 5, 2019 Category: OBGYN Source Type: research

Second-trimester maternal lipid profiles predict pregnancy complications in an age-dependent manner
ConclusionsSecond-trimester lipid profiles might predict pregnancy complications varied by maternal age. This suggested that individualized prenatal care strategies should be established for women with advanced and normal maternal age to prevent pregnancy complications. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - March 5, 2019 Category: OBGYN Source Type: research

Patients ’ perspectives towards malignant ascites: results of a prospective observational trial regarding expectations, characteristics and quality of life—a study of the North-Eastern-German Society of Gynecological Oncology
ConclusionMA has a significantly impact on QoL measurements in cancer patients and might influence everyday activities including basic needs like eating, walking and body care. There is a high need for more information and education of patients with MA (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - March 5, 2019 Category: OBGYN Source Type: research

Obstetrical outcomes of embryo reduction and fetal reduction compared to non-reduced twin pregnancies
ConclusionsCompared with the control group, ER in twins had a higher miscarriage and fetal loss rate, whereas FR in twins was similar to the control group. So, the FR procedure is overall a better and safer approach of MPR in reducing morbidity and mortality in HOMPs. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - March 2, 2019 Category: OBGYN Source Type: research

Efficacy of pegylated liposomal doxorubicin maintenance therapy in platinum-sensitive recurrent epithelial ovarian cancer: a retrospective study
ConclusionOur study suggests that PLD maintenance therapy for platinum-sensitive recurrent ovarian cancer is relatively well tolerated with the use of dose reduction to manage toxicity. Our study suggests that PLD maintenance therapy may be effective for women with platinum-sensitive recurrent epithelial ovarian cancer. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - March 1, 2019 Category: OBGYN Source Type: research