Safety and Efficacy of Stereotactic Body Radiotherapy for Ultra-Central Thoracic Tumours: A Single Centre Retrospective Review
CONCLUSION: In the largest case series of ultra-central thoracic SBRT to date, homogenously prescribed SBRT was associated with relatively low rates of severe toxicity and LF. Predictors of toxicity should be interpreted in the context of the heterogeneity in toxicities observed.PMID:38621607 | DOI:10.1016/j.ijrobp.2024.04.009 (Source: Health Physics)
Source: Health Physics - April 15, 2024 Category: Physics Authors: George J Li Hendrick Tan Humza Nusrat Joe Chang Hanbo Chen Ian Poon Jeevin Shahi May Tsao Yee Ung Patrick Cheung Alexander V Louie Source Type: research
Household Air Pollution Interventions to Improve Health in Low- and Middle-Income Countries: An Official American Thoracic Society Research Statement
Conclusions: HAP is associated with adverse health effects in observational studies. However, it remains unclear which household energy interventions reduce exposure, improve health, can be scaled, and are sustainable. Researchers should engage with policy makers and practitioners working to scale cleaner energy solutions to understand and address their information needs.PMID:38619436 | DOI:10.1164/rccm.202402-0398ST (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - April 15, 2024 Category: Intensive Care Authors: Peggy S Lai Nicholas L Lam Bill Gallery Alison G Lee Heather Adair-Rohani Donee Alexander Kalpana Balakrishnan Iwona Bisaga Zoe A Chafe Thomas Clasen Anait é Díaz-Artiga Andrew Grieshop Kat Harrison Stella M Hartinger Darby Jack Seyram Kaali Melissa Lyd Source Type: research
Pulmonology: What You May Have Missed in 2023
Ann Intern Med. 2024 Apr 16. doi: 10.7326/M24-0613. Online ahead of print.ABSTRACTThe field of pulmonology saw significant advances in 2023. The publications highlighted in this article address advances and changes in practice related to asthma, chronic obstructive pulmonary disease (COPD), interstitial lung disease, pleural disorders, and sleep-disordered breathing. One article reviews data examining the efficacy of vaccination against respiratory syncytial virus, a respiratory viral illness that has had devastating effects globally. Four studies evaluate the role of various therapies in COPD, including dupilumab, ensifen...
Source: Annals of Internal Medicine - April 15, 2024 Category: Internal Medicine Authors: Aram Karkar Sana Khan Rebecca O'Leary Albina Tyker Michael Unger Source Type: research
COVID-19 Pandemic: Impact and rapid reaction of Urology
Actas Urol Esp. 2020 Sep;44(7):450-457. doi: 10.1016/j.acuro.2020.04.006. Epub 2020 Apr 24.ABSTRACTThe COVID-19 pandemic caused by the SARS-CoV-2 virus has caused tens of thousands of deaths in Spain and has managed to breakdown the healthcare system hospitals in the Community of Madrid, largely due to its tendency to cause severe pneumonia, requiring ventilatory support. This fact has caused our center to collapse, with 130% of its beds occupied by COVID-19 patients, thus causing the absolute cessation of activity of the urology service, the practical disappearance of resident training programs, and the incorporation of a...
Source: Actas Urologicas Espanolas - April 15, 2024 Category: Urology & Nephrology Authors: V Hevia J Lorca M Hevia A Dom ínguez J L ópez-Plaza A Artiles S Álvarez Á Sánchez A Fraile L L ópez-Fando E Sanz M Ruiz E Alcaraz F J Burgos Source Type: research
Household Air Pollution Interventions to Improve Health in Low- and Middle-Income Countries: An Official American Thoracic Society Research Statement
Conclusions: HAP is associated with adverse health effects in observational studies. However, it remains unclear which household energy interventions reduce exposure, improve health, can be scaled, and are sustainable. Researchers should engage with policy makers and practitioners working to scale cleaner energy solutions to understand and address their information needs.PMID:38619436 | DOI:10.1164/rccm.202402-0398ST (Source: Respiratory Care)
Source: Respiratory Care - April 15, 2024 Category: Respiratory Medicine Authors: Peggy S Lai Nicholas L Lam Bill Gallery Alison G Lee Heather Adair-Rohani Donee Alexander Kalpana Balakrishnan Iwona Bisaga Zoe A Chafe Thomas Clasen Anait é Díaz-Artiga Andrew Grieshop Kat Harrison Stella M Hartinger Darby Jack Seyram Kaali Melissa Lyd Source Type: research
Comparative study of imaging and pathology of primary mucinous adenocarcinoma with different imaging manifestations
CONCLUSION: The different imaging manifestations of mucinous adenocarcinoma are possibly due to the different amounts or viscosity of mucus produced, and the mechanisms of its formation may include (1) tumour cells in different shapes have different abilities to produce mucus; (2) tumours in different stages produce different amounts or viscosity of mucus; and (3) the TTF-1 and ALK genes affect the production of mucus.PMID:38616354 | DOI:10.1111/crj.13750 (Source: Respiratory Care)
Source: Respiratory Care - April 15, 2024 Category: Respiratory Medicine Authors: Jun Han Jie Gao Demei Chen Mou Du Yuxin Wu Xidong Ma Mei Xie Hua Han Chongchong Wu Xinying Xue Source Type: research
CNS Aspergillosis and Cryptococcosis with Cytomegalovirus Pneumonia in a Patient with Chronic Lymphocytic Leukemia Treated with Acalabrutinib
We describe a 68-year-old male who developed multiple bacterial, fungal and viral infections while on treatment with acalabrutinib. To our knowledge, this is the first reported case of concomitant CNS infections with Cryptococcus neoformans and Aspergillus fumigatus, along with cytomegalovirus (CMV) and herpes simplex virus type 1 (HSV-1) pneumonia while on acalabrutinib. This case adds to the scarce literature of fungal and bacterial infections associated with acalabrutinib, raising the suspicion that infection risk is a medication class effect for BTKis.PMID:38621678 | DOI:10.1177/08971900241247660 (Source: Herpes)
Source: Herpes - April 15, 2024 Category: Infectious Diseases Authors: Taylor Fallin Erica Thacker Syeda Sahra Emily A Siegrist Bryan P White Katherine Summers Dena Shibib Joseph Sassine Source Type: research
Household Air Pollution Interventions to Improve Health in Low- and Middle-Income Countries: An Official American Thoracic Society Research Statement
Conclusions: HAP is associated with adverse health effects in observational studies. However, it remains unclear which household energy interventions reduce exposure, improve health, can be scaled, and are sustainable. Researchers should engage with policy makers and practitioners working to scale cleaner energy solutions to understand and address their information needs.PMID:38619436 | DOI:10.1164/rccm.202402-0398ST (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 15, 2024 Category: Respiratory Medicine Authors: Peggy S Lai Nicholas L Lam Bill Gallery Alison G Lee Heather Adair-Rohani Donee Alexander Kalpana Balakrishnan Iwona Bisaga Zoe A Chafe Thomas Clasen Anait é Díaz-Artiga Andrew Grieshop Kat Harrison Stella M Hartinger Darby Jack Seyram Kaali Melissa Lyd Source Type: research
Comparative study of imaging and pathology of primary mucinous adenocarcinoma with different imaging manifestations
CONCLUSION: The different imaging manifestations of mucinous adenocarcinoma are possibly due to the different amounts or viscosity of mucus produced, and the mechanisms of its formation may include (1) tumour cells in different shapes have different abilities to produce mucus; (2) tumours in different stages produce different amounts or viscosity of mucus; and (3) the TTF-1 and ALK genes affect the production of mucus.PMID:38616354 | DOI:10.1111/crj.13750 (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - April 15, 2024 Category: Cancer & Oncology Authors: Jun Han Jie Gao Demei Chen Mou Du Yuxin Wu Xidong Ma Mei Xie Hua Han Chongchong Wu Xinying Xue Source Type: research
Successful Recovery of a Catatonic Patient with Severe Pneumonia and Respiratory Failure: Modified Electroconvulsive Therapy Following Tracheotomy
In this report, we present a case of catatonia complicated by severe pneumonia and respiratory failure, successfully managed with modified electroconvulsive therapy alongside tracheotomy. We hope this case provides valuable insights for psychiatrists encountering similar scenarios, facilitating the development of rational therapeutic strategies for prompt improvement of patient condition.PMID:38622014 | DOI:10.62641/aep.v52i2.1528 (Source: Actas Espanolas de Psiquiatria)
Source: Actas Espanolas de Psiquiatria - April 15, 2024 Category: Psychiatry Authors: Yuejing Wu Qian He Li Zhang Tao Li Fugang Luo Source Type: research
Exploring the immune-inflammatory mechanism of Maxing Shigan Decoction in treating influenza virus A-induced pneumonia based on an integrated strategy of single-cell transcriptomics and systems biology
CONCLUSION: MXSGD may play an anti-inflammatory and immunoregulatory role by regulating intestinal microbiome and intestinal metabolic small molecules, and ultimately play a role in the treatment of influenza A virus pneumonia.PMID:38622728 | DOI:10.1186/s40001-024-01777-9 (Source: Cell Research)
Source: Cell Research - April 15, 2024 Category: Cytology Authors: Shiying Zhang Bei Li Liuting Zeng Kailin Yang Junyao Jiang Fangguo Lu Ling Li Weiqing Li Source Type: research
The Outcomes of Patients with Omicron Variant Infection who Undergo Elective Surgery: A Propensity-score-matched Case-control Study
Conclusion: Omicron infection does not significantly increase the risk of perioperative major complications. The Omicron infection may not be a sufficient risk factor to postpone elective surgery.PMID:38616997 | PMC:PMC11008485 | DOI:10.7150/ijms.90695 (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - April 15, 2024 Category: Biomedical Science Authors: Xiaojuan Xiong Rui Li Hong Yan Qingxiang Mao Source Type: research
Safety and Efficacy of Stereotactic Body Radiotherapy for Ultra-Central Thoracic Tumours: A Single Centre Retrospective Review
CONCLUSION: In the largest case series of ultra-central thoracic SBRT to date, homogenously prescribed SBRT was associated with relatively low rates of severe toxicity and LF. Predictors of toxicity should be interpreted in the context of the heterogeneity in toxicities observed.PMID:38621607 | DOI:10.1016/j.ijrobp.2024.04.009 (Source: Health Physics)
Source: Health Physics - April 15, 2024 Category: Physics Authors: George J Li Hendrick Tan Humza Nusrat Joe Chang Hanbo Chen Ian Poon Jeevin Shahi May Tsao Yee Ung Patrick Cheung Alexander V Louie Source Type: research
Severe acute respiratory syndrome
Med Mal Infect. 2003 Jun;33(6):281-286. doi: 10.1016/S0399-077X(03)00200-2. Epub 2003 Jun 6.ABSTRACTIn the Fall of 2002 a report from Guangdong Province in China showed the occurrence of an outbreak of atypical pneumonia. This outbreak rapidly progressed from China to Hong Kong, Singapore, Toronto, and the USA, to more than 25 countries worldwide and almost 3500 cases to date in april 2003. The clinical features associate a fever with mild respiratory symptoms which can progress to a typical acute respiratory distress syndrome requiring intensive care unit admission. Enteric forms with diarrhea were recently described in H...
Source: Medecine et Maladies Infectieuses - April 15, 2024 Category: Infectious Diseases Authors: B Guery S Alfandari O Leroy H Georges T D'escrivan E Kipnis Y Mouton Y Yazdanpanah Source Type: research
Rational use of antibiotics treatment in acute bronchitis
Med Mal Infect. 1992 Feb;22:149-152. doi: 10.1016/S0399-077X(05)81464-7. Epub 2005 Jun 20.ABSTRACTAcute bronchitis in healthy patient in mainly related to virus. Intra-cellular bacteria, Mycoplasma pneumonia are rarely involved. For these reasons, macrolides or cyclines (except for children) are justified in first line treatment. For patients with acute exacerbation of chronic bronchitis, the choice of the treatment needs to be discuss. At the initial stage, most of the pathogens involved are those of acute bronchitis. Antibiotic is only prescribes for the prevention of a superinfection; this kind of prophylaxis has to be ...
Source: Medecine et Maladies Infectieuses - April 15, 2024 Category: Infectious Diseases Authors: P Dellamonica Source Type: research
