Noninvasive Ambulatory Electrocardiographic Markers from Patients with COVID-19 Pneumonia: A Report of Three Cases
Medicina (Kaunas). 2024 Apr 19;60(4):655. doi: 10.3390/medicina60040655.ABSTRACTCoronavirus disease 2019 (COVID-19) has affected medical practice. More than 7,000,000 patients died worldwide after being infected with COVID-19; however, no specific laboratory markers have yet been established to predict death related to this disease. In contrast, electrocardiographic changes due to COVID-19 include QT prolongation and ST-T changes; however, there have not been studies on the ambulatory electrocardiographic markers of COVID-19. We encountered three patients diagnosed as having COVID-19 who did not have a prior history of sig...
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Motohiro Kimata Kenichi Hashimoto Naomi Harada Yusuke Kawamura Yoshifumi Kimizuka Yuji Fujikura Mayuko Kaneko Nobuaki Kiriu Yasumasa Sekine Natsumi Iwabuchi Tetsuro Kiyozumi Akihiko Kawana Susumu Matsukuma Yuji Tanaka Source Type: research
Noninvasive Ambulatory Electrocardiographic Markers from Patients with COVID-19 Pneumonia: A Report of Three Cases
Medicina (Kaunas). 2024 Apr 19;60(4):655. doi: 10.3390/medicina60040655.ABSTRACTCoronavirus disease 2019 (COVID-19) has affected medical practice. More than 7,000,000 patients died worldwide after being infected with COVID-19; however, no specific laboratory markers have yet been established to predict death related to this disease. In contrast, electrocardiographic changes due to COVID-19 include QT prolongation and ST-T changes; however, there have not been studies on the ambulatory electrocardiographic markers of COVID-19. We encountered three patients diagnosed as having COVID-19 who did not have a prior history of sig...
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Motohiro Kimata Kenichi Hashimoto Naomi Harada Yusuke Kawamura Yoshifumi Kimizuka Yuji Fujikura Mayuko Kaneko Nobuaki Kiriu Yasumasa Sekine Natsumi Iwabuchi Tetsuro Kiyozumi Akihiko Kawana Susumu Matsukuma Yuji Tanaka Source Type: research
Noninvasive Ambulatory Electrocardiographic Markers from Patients with COVID-19 Pneumonia: A Report of Three Cases
Medicina (Kaunas). 2024 Apr 19;60(4):655. doi: 10.3390/medicina60040655.ABSTRACTCoronavirus disease 2019 (COVID-19) has affected medical practice. More than 7,000,000 patients died worldwide after being infected with COVID-19; however, no specific laboratory markers have yet been established to predict death related to this disease. In contrast, electrocardiographic changes due to COVID-19 include QT prolongation and ST-T changes; however, there have not been studies on the ambulatory electrocardiographic markers of COVID-19. We encountered three patients diagnosed as having COVID-19 who did not have a prior history of sig...
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Motohiro Kimata Kenichi Hashimoto Naomi Harada Yusuke Kawamura Yoshifumi Kimizuka Yuji Fujikura Mayuko Kaneko Nobuaki Kiriu Yasumasa Sekine Natsumi Iwabuchi Tetsuro Kiyozumi Akihiko Kawana Susumu Matsukuma Yuji Tanaka Source Type: research
Noninvasive Ambulatory Electrocardiographic Markers from Patients with COVID-19 Pneumonia: A Report of Three Cases
Medicina (Kaunas). 2024 Apr 19;60(4):655. doi: 10.3390/medicina60040655.ABSTRACTCoronavirus disease 2019 (COVID-19) has affected medical practice. More than 7,000,000 patients died worldwide after being infected with COVID-19; however, no specific laboratory markers have yet been established to predict death related to this disease. In contrast, electrocardiographic changes due to COVID-19 include QT prolongation and ST-T changes; however, there have not been studies on the ambulatory electrocardiographic markers of COVID-19. We encountered three patients diagnosed as having COVID-19 who did not have a prior history of sig...
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Motohiro Kimata Kenichi Hashimoto Naomi Harada Yusuke Kawamura Yoshifumi Kimizuka Yuji Fujikura Mayuko Kaneko Nobuaki Kiriu Yasumasa Sekine Natsumi Iwabuchi Tetsuro Kiyozumi Akihiko Kawana Susumu Matsukuma Yuji Tanaka Source Type: research
Neutrophil Extracellular Traps and Respiratory Disease
J Clin Med. 2024 Apr 19;13(8):2390. doi: 10.3390/jcm13082390.ABSTRACTExtracellular traps made by neutrophils (NETs) and other leukocytes such as macrophages and eosinophils have a key role in the initial immune response to infection but are highly inflammatory and may contribute to tissue damage. They are particularly relevant to lung disease, with the pulmonary anatomy facilitating their ability to fully extend into the airways/alveolar space. There has been a rapid expansion in the number of published studies demonstrating their role in a variety of important respiratory diseases including chronic obstructive pulmonary d...
Source: Clinical Lung Cancer - April 27, 2024 Category: Cancer & Oncology Authors: Paul T King Lovisa Dousha Source Type: research
OriPlex: Origami-enabled multiplexed detection of respiratory pathogens
Biosens Bioelectron. 2024 Apr 25;257:116341. doi: 10.1016/j.bios.2024.116341. Online ahead of print.ABSTRACTOrigami biosensors leverage paper foldability to develop total analysis systems integrated in a single piece of paper. This capability can also be utilized to incorporate additional features that would be difficult to achieve with rigid substrates. In this article, we report a new design for 3D origami biosensors called OriPlex, which leverages the foldability of filter paper for the multiplexed detection of bacterial pathogens. OriPlex immunosensors detect pathogens by folding nanoparticle reservoirs containing diff...
Source: Biosensors and Bioelectronics - April 27, 2024 Category: Biotechnology Authors: Andreu Vaquer Cristina Adrover-Jaume Antonio Clemente Julia Viana Roc ío Rodríguez Estrella Rojo-Molinero Antonio Oliver Roberto de la Rica Source Type: research
Noninvasive Ambulatory Electrocardiographic Markers from Patients with COVID-19 Pneumonia: A Report of Three Cases
Medicina (Kaunas). 2024 Apr 19;60(4):655. doi: 10.3390/medicina60040655.ABSTRACTCoronavirus disease 2019 (COVID-19) has affected medical practice. More than 7,000,000 patients died worldwide after being infected with COVID-19; however, no specific laboratory markers have yet been established to predict death related to this disease. In contrast, electrocardiographic changes due to COVID-19 include QT prolongation and ST-T changes; however, there have not been studies on the ambulatory electrocardiographic markers of COVID-19. We encountered three patients diagnosed as having COVID-19 who did not have a prior history of sig...
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Motohiro Kimata Kenichi Hashimoto Naomi Harada Yusuke Kawamura Yoshifumi Kimizuka Yuji Fujikura Mayuko Kaneko Nobuaki Kiriu Yasumasa Sekine Natsumi Iwabuchi Tetsuro Kiyozumi Akihiko Kawana Susumu Matsukuma Yuji Tanaka Source Type: research
Neutrophil Extracellular Traps and Respiratory Disease
J Clin Med. 2024 Apr 19;13(8):2390. doi: 10.3390/jcm13082390.ABSTRACTExtracellular traps made by neutrophils (NETs) and other leukocytes such as macrophages and eosinophils have a key role in the initial immune response to infection but are highly inflammatory and may contribute to tissue damage. They are particularly relevant to lung disease, with the pulmonary anatomy facilitating their ability to fully extend into the airways/alveolar space. There has been a rapid expansion in the number of published studies demonstrating their role in a variety of important respiratory diseases including chronic obstructive pulmonary d...
Source: Clinical Lung Cancer - April 27, 2024 Category: Cancer & Oncology Authors: Paul T King Lovisa Dousha Source Type: research
Frequency of infections during rituximab treatment of autoimmune blistering diseases
This study investigates the frequency of infections in autoimmune blistering disease (AIBD) patients treated with rituximab and evaluates the difference in infectious complications in patients on concomitant antibiotic and/or antiviral prophylaxis. The study retrospectively reviewed 43 AIBD patients who received rituximab over a five-year interval. The patients were categorized based on prophylaxis type (antibiotic, antiviral, or both) and concomitant immunosuppression status, which we defined as treatment with an immunosuppressive medication during the time frame they were given Rituximab. Our findings suggest that concom...
Source: Archives of Dermatological Research - April 27, 2024 Category: Dermatology Source Type: research
High-resolution genomics identifies pneumococcal diversity and persistence of vaccine types in children with community-acquired pneumonia in the UK and Ireland
Streptococcus pneumoniae is a global cause of community-acquired pneumonia (CAP) and invasive disease in children. The CAP-IT trial (grant No. 13/88/11; (Source: BMC Microbiology)
Source: BMC Microbiology - April 27, 2024 Category: Microbiology Authors: Juan Pablo Rodriguez-Ruiz, Basil Britto Xavier, Wolfgang St öhr, Liesbet van Heirstraeten, Christine Lammens, Adam Finn, Herman Goossens, Julia Anna Bielicki, Michael Sharland and Surbhi Malhotra-Kumar Tags: Research Source Type: research
Frequency of infections during rituximab treatment of autoimmune blistering diseases
This study investigates the frequency of infections in autoimmune blistering disease (AIBD) patients treated with rituximab and evaluates the difference in infectious complications in patients on concomitant antibiotic and/or antiviral prophylaxis. The study retrospectively reviewed 43 AIBD patients who received rituximab over a five-year interval. The patients were categorized based on prophylaxis type (antibiotic, antiviral, or both) and concomitant immunosuppression status, which we defined as treatment with an immunosuppressive medication during the time frame they were given Rituximab. Our findings suggest that concom...
Source: Archives of Dermatological Research - April 27, 2024 Category: Dermatology Source Type: research
Dysphagia Is an Underrecognized Risk Factor for Viral Pneumonia Severity
This study showed that a pre-existing diagnosis of dysphagia was independently associated with COVID-19 severity in adults ≥50 years of age. (Source: Dysphagia)
Source: Dysphagia - April 27, 2024 Category: Speech-Language Pathology Source Type: research
AAV-vectored expression of monospecific or bispecific monoclonal antibodies protects mice from lethal Pseudomonas aeruginosa pneumonia
Gene Therapy, Published online: 27 April 2024; doi:10.1038/s41434-024-00453-1AAV-vectored expression of monospecific or bispecific monoclonal antibodies protects mice from lethal Pseudomonas aeruginosa pneumonia (Source: Gene Therapy)
Source: Gene Therapy - April 27, 2024 Category: Genetics & Stem Cells Authors: Jordyn A. Lopes Nicole E. Garnier Yanlong Pei Jacob G. E. Yates Elena S. B. Campbell Melanie M. Goens Madison E. Hughes Amira D. Rghei Brenna A. Y. Stevens Matthew M. Guilleman Brad Thompson Cezar M. Khursigara Leonardo Susta Sarah K. Wootton Source Type: research
TRIM27-Induced Protective Autophagy: A Novel Therapeutic Approach for Pneumonia
CONCLUSION: The induction of TRIM27 overexpression emerges as a potential and effective pneumonia treatment. The underlying mechanism may involve inducing protective autophagy, thereby reducing oxidative stress and cell pyroptosis.PMID:38665029 | DOI:10.24976/Discov.Med.202436183.76 (Source: Discovery Medicine)
Source: Discovery Medicine - April 26, 2024 Category: Research Authors: Yajiao Pang Hongrong Wang Qiaoyi Xie Tingting Ma Source Type: research
