Bicistronic transfer of CDKN2A and p53 culminates in collaborative killing of human lung cancer cells in vitro and in vivo
Gene Therapy, Published online: 22 August 2019; doi:10.1038/s41434-019-0096-1Bicistronic transfer of CDKN2A and p53 culminates in collaborative killing of human lung cancer cells in vitro and in vivo (Source: Gene Therapy)
Source: Gene Therapy - August 22, 2019 Category: Genetics & Stem Cells Authors: Juliana G. Xande Ana P. Dias Rodrigo E. Tamura Mario C. Cruz B árbara Brito Robledo A. Ferreira Bryan E. Strauss Eugenia Costanzi-Strauss Source Type: research

Inferring novel genes related to colorectal cancer via random walk with restart algorithm
Gene Therapy, Published online: 15 July 2019; doi:10.1038/s41434-019-0090-7Inferring novel genes related to colorectal cancer via random walk with restart algorithm (Source: Gene Therapy)
Source: Gene Therapy - July 15, 2019 Category: Genetics & Stem Cells Authors: Sheng Lu Zheng-Gang Zhu Wen-Cong Lu Source Type: research

AAVrh-10 transduces outer retinal cells in rodents and rabbits following intravitreal administration
Gene Therapy, Published online: 15 July 2019; doi:10.1038/s41434-019-0094-3AAVrh-10 transduces outer retinal cells in rodents and rabbits following intravitreal administration (Source: Gene Therapy)
Source: Gene Therapy - July 15, 2019 Category: Genetics & Stem Cells Authors: Yong Zeng Haohua Qian Zhijian Wu Dario Marangoni Paul A. Sieving Ronald A. Bush Source Type: research

Inside out: optimization of lipid nanoparticle formulations for exterior complexation and in vivo delivery of saRNA
Gene Therapy, Published online: 12 July 2019; doi:10.1038/s41434-019-0095-2Inside out: optimization of lipid nanoparticle formulations for exterior complexation and in vivo delivery of saRNA (Source: Gene Therapy)
Source: Gene Therapy - July 12, 2019 Category: Genetics & Stem Cells Authors: Anna K. Blakney Paul F. McKay B árbara Ibarzo Yus Yoann Aldon Robin J. Shattock Source Type: research

Beyond cystic fibrosis transmembrane conductance regulator therapy: a perspective on gene therapy and small molecule treatment for cystic fibrosis
Gene Therapy, Published online: 12 July 2019; doi:10.1038/s41434-019-0092-5Beyond cystic fibrosis transmembrane conductance regulator therapy: a perspective on gene therapy and small molecule treatment for cystic fibrosis (Source: Gene Therapy)
Source: Gene Therapy - July 12, 2019 Category: Genetics & Stem Cells Authors: Elena K. Schneider-Futschik Source Type: research

Gene therapy of hematological disorders: current challenges
Gene Therapy, Published online: 12 July 2019; doi:10.1038/s41434-019-0093-4Gene therapy of hematological disorders: current challenges (Source: Gene Therapy)
Source: Gene Therapy - July 12, 2019 Category: Genetics & Stem Cells Authors: Amr M. Al-Saif Source Type: research

A next-generation sequencing method for gene doping detection that distinguishes low levels of plasmid DNA against a background of genomic DNA
Gene Therapy, Published online: 11 July 2019; doi:10.1038/s41434-019-0091-6A next-generation sequencing method for gene doping detection that distinguishes low levels of plasmid DNA against a background of genomic DNA (Source: Gene Therapy)
Source: Gene Therapy - July 11, 2019 Category: Genetics & Stem Cells Authors: Eddy N. de Boer Petra E. van der Wouden Lennart F. Johansson Cleo C. van Diemen Hidde J. Haisma Source Type: research

Gene therapy for refractory angina and cell therapy for heart failure: experience of a Brazilian research group
Gene Therapy, Published online: 05 July 2019; doi:10.1038/s41434-019-0087-2Gene therapy for refractory angina and cell therapy for heart failure: experience of a Brazilian research group (Source: Gene Therapy)
Source: Gene Therapy - July 5, 2019 Category: Genetics & Stem Cells Authors: Roberto Tofani Sant ’Anna Bruna Eibel Melissa Medeiros Markoski Clarissa Garcia Rodrigues Felipe Borsu de Salles Imarilde In ês Giusti Ivo Abrah ão Nesralla Nance Beyer Nardi Renato Abdala Karam Kalil Source Type: research

Genetic therapies, human genetic enhancement, and … eugenics?
Gene Therapy, Published online: 04 July 2019; doi:10.1038/s41434-019-0088-1Genetic therapies, human genetic enhancement, and … eugenics? (Source: Gene Therapy)
Source: Gene Therapy - July 4, 2019 Category: Genetics & Stem Cells Authors: Theodore Friedmann Source Type: research

Design and applications of gene therapy vectors for mucopolysaccharidosis in Colombia
Gene Therapy, Published online: 02 July 2019; doi:10.1038/s41434-019-0086-3Design and applications of gene therapy vectors for mucopolysaccharidosis in Colombia (Source: Gene Therapy)
Source: Gene Therapy - July 2, 2019 Category: Genetics & Stem Cells Authors: Carlos J. Alm éciga-Diaz Luis A. Barrera Source Type: research

AAV9 Vector: a Novel modality in gene therapy for spinal muscular atrophy
Gene Therapy, Published online: 26 June 2019; doi:10.1038/s41434-019-0085-4AAV9 Vector: a Novel modality in gene therapy for spinal muscular atrophy (Source: Gene Therapy)
Source: Gene Therapy - June 26, 2019 Category: Genetics & Stem Cells Authors: Rithu Pattali Yongchao Mou Xue-Jun Li Source Type: research

Effects of a combinatorial treatment with gene and cell therapy on retinal ganglion cell survival and axonal outgrowth after optic nerve injury
Gene Therapy, Published online: 26 June 2019; doi:10.1038/s41434-019-0089-0Effects of a combinatorial treatment with gene and cell therapy on retinal ganglion cell survival and axonal outgrowth after optic nerve injury (Source: Gene Therapy)
Source: Gene Therapy - June 26, 2019 Category: Genetics & Stem Cells Authors: Gabriel Nascimento-dos-Santos Leandro Coelho Teixeira-Pinheiro Almir Jord ão da Silva-Júnior Luiza Rachel Pinheiro de Carvalho Louise Alessandra Mesentier-Louro William W. Hauswirth Rosalia Mendez-Otero Marcelo Felippe Santiago Hilda Petrs-Silva Source Type: research

Safety profiling of genetically engineered Pim-1 kinase overexpression for oncogenicity risk in human c-kit+ cardiac interstitial cells
Gene Therapy, Published online: 25 June 2019; doi:10.1038/s41434-019-0084-5Safety profiling of genetically engineered Pim-1 kinase overexpression for oncogenicity risk in human c-kit+ cardiac interstitial cells (Source: Gene Therapy)
Source: Gene Therapy - June 25, 2019 Category: Genetics & Stem Cells Authors: Kathleen Broughton Kelli Korski Oscar Echeagaray Robert Adamson Walter Dembitsky Zhibing Lu Erik Schaefer Mark A. Sussman Source Type: research

Bringing balance to the force–regulatable gene therapy for epilepsy
Gene Therapy, Published online: 28 May 2019; doi:10.1038/s41434-019-0083-6Bringing balance to the force–regulatable gene therapy for epilepsy (Source: Gene Therapy)
Source: Gene Therapy - May 28, 2019 Category: Genetics & Stem Cells Authors: Arnaud J. Ruiz Ahad A. Rahim Source Type: research

Feasibility of using NF1-GRD and AAV for gene replacement therapy in NF1-associated tumors
Gene Therapy, Published online: 24 May 2019; doi:10.1038/s41434-019-0080-9Feasibility of using NF1-GRD and AAV for gene replacement therapy in NF1-associated tumors (Source: Gene Therapy)
Source: Gene Therapy - May 24, 2019 Category: Genetics & Stem Cells Authors: Ren-Yuan Bai Dominic Esposito Ada J. Tam Frank McCormick Gregory J. Riggins D. Wade Clapp Verena Staedtke Source Type: research

AAV-encoded CaV2.2 peptide aptamer CBD3A6K for primary sensory neuron-targeted treatment of established neuropathic pain
Gene Therapy, Published online: 22 May 2019; doi:10.1038/s41434-019-0082-7AAV-encoded CaV2.2 peptide aptamer CBD3A6K for primary sensory neuron-targeted treatment of established neuropathic pain (Source: Gene Therapy)
Source: Gene Therapy - May 22, 2019 Category: Genetics & Stem Cells Authors: Hongwei Yu Seung Min Shin Hongfei Xiang Dongman Chao Yongsong Cai Hao Xu Rajesh Khanna Bin Pan Quinn H. Hogan Source Type: research

Bat adeno-associated viruses as gene therapy vectors with the potential to evade human neutralizing antibodies
Gene Therapy, Published online: 20 May 2019; doi:10.1038/s41434-019-0081-8Bat adeno-associated viruses as gene therapy vectors with the potential to evade human neutralizing antibodies (Source: Gene Therapy)
Source: Gene Therapy - May 20, 2019 Category: Genetics & Stem Cells Authors: Ya Li Jialu Li Yunbo Liu Zhengli Shi Haizhou Liu Yuquan Wei Lin Yang Source Type: research

Delivering cellular and gene therapies to patients: solutions for realizing the potential of the next generation of medicine
Delivering cellular and gene therapies to patients: solutions for realizing the potential of the next generation of medicine, Published online: 25 April 2019; doi:10.1038/s41434-019-0074-7Delivering cellular and gene therapies to patients: solutions for realizing the potential of the next generation of medicine (Source: Gene Therapy)
Source: Gene Therapy - April 25, 2019 Category: Genetics & Stem Cells Authors: Kris Elverum Maria Whitman Source Type: research

Reviewer recognition
Reviewer recognition, Published online: 18 April 2019; doi:10.1038/s41434-019-0065-8Reviewer recognition (Source: Gene Therapy)
Source: Gene Therapy - April 18, 2019 Category: Genetics & Stem Cells Source Type: research

Cell therapy for Parkinson′s disease is coming of age: current challenges and future prospects with a focus on immunomodulation
Cell therapy for Parkinson′s disease is coming of age: current challenges and future prospects with a focus on immunomodulationCell therapy for Parkinson′s disease is coming of age: current challenges and future prospects with a focus on immunomodulation, Published online: 16 April 2019; doi:10.1038/s41434-019-0077-4Cell therapy for Parkinson′s disease is coming of age: current challenges and future prospects with a focus on immunomodulation (Source: Gene Therapy)
Source: Gene Therapy - April 16, 2019 Category: Genetics & Stem Cells Authors: Shirley D. Wenker Fernando J. Pitossi Source Type: research

Magic realism: a Latin American paradigm for stem cell research & development?
Magic realism: a Latin American paradigm for stem cell research & development?, Published online: 08 April 2019; doi:10.1038/s41434-019-0079-2Magic realism: a Latin American paradigm for stem cell research & development? (Source: Gene Therapy)
Source: Gene Therapy - April 8, 2019 Category: Genetics & Stem Cells Authors: Maroun Khoury Fernando E. Figueroa Source Type: research

Adeno-associated virus neutralising antibodies in type 1 diabetes mellitus
Adeno-associated virus neutralising antibodies in type 1 diabetes mellitus, Published online: 08 April 2019; doi:10.1038/s41434-019-0076-5Adeno-associated virus neutralising antibodies in type 1 diabetes mellitus (Source: Gene Therapy)
Source: Gene Therapy - April 8, 2019 Category: Genetics & Stem Cells Authors: Slawomir Andrzejewski Aparna Murali Charmaine Ramlogan-Steel Katie P. Edwards Nathan Efron Jason C. Steel Christopher J. Layton Source Type: research

Regulated ex vivo regional gene therapy for bone repair using an inducible caspase-9 suicide gene system
Regulated ex vivo regional gene therapy for bone repair using an inducible caspase-9 suicide gene system, Published online: 08 April 2019; doi:10.1038/s41434-019-0069-4Regulated ex vivo regional gene therapy for bone repair using an inducible caspase-9 suicide gene system (Source: Gene Therapy)
Source: Gene Therapy - April 8, 2019 Category: Genetics & Stem Cells Authors: Sofia Bougioukli Venus Vakhshori Brandon Ortega Osamu Sugiyama Jay Lieberman Source Type: research

Polarized AAVR expression determines infectivity by AAV gene therapy vectors
Polarized AAVR expression determines infectivity by AAV gene therapy vectors, Published online: 08 April 2019; doi:10.1038/s41434-019-0078-3Polarized AAVR expression determines infectivity by AAV gene therapy vectors (Source: Gene Therapy)
Source: Gene Therapy - April 8, 2019 Category: Genetics & Stem Cells Authors: Bradley A. Hamilton Xiaopeng Li Alejandro A. Pezzulo Mahmoud H. Abou Alaiwa Joseph Zabner Source Type: research

Astrocyte-selective AAV gene therapy through the endogenous GFAP promoter results in robust transduction in the rat spinal cord following injury
Astrocyte-selective AAV gene therapy through the endogenous GFAP promoter results in robust transduction in the rat spinal cord following injury, Published online: 08 April 2019; doi:10.1038/s41434-019-0075-6Astrocyte-selective AAV gene therapy through the endogenous GFAP promoter results in robust transduction in the rat spinal cord following injury (Source: Gene Therapy)
Source: Gene Therapy - April 8, 2019 Category: Genetics & Stem Cells Authors: Jarred M. Griffin Barbara Fackelmeier Dahna M. Fong Alexander Mouravlev Deborah Young Simon J. O ’Carroll Source Type: research

Inhibition of microRNA-495 suppresses chondrocyte apoptosis through activation of the NF-κB signaling pathway by regulating CCL4 in osteoarthritis
Inhibition of microRNA-495 suppresses chondrocyte apoptosis through activation of the NF-κB signaling pathway by regulating CCL4 in osteoarthritisInhibition of microRNA-495 suppresses chondrocyte apoptosis through activation of the NF-κB signaling pathway by regulating CCL4 in osteoarthritis, Published online: 02 April 2019; doi:10.1038/s41434-019-0068-5Inhibition of microRNA-495 suppresses chondrocyte apoptosis through activation of the NF-κB signaling pathway by regulating CCL4 in osteoarthritis (Source: Gene Therapy)
Source: Gene Therapy - April 2, 2019 Category: Genetics & Stem Cells Authors: Da-Wei Yang Gui-Bin Qian Ming-Jiu Jiang Peng Wang Kun-Zheng Wang Source Type: research

A novel xenograft mouse model for testing approaches targeting human kappa light-chain diseases
A novel xenograft mouse model for testing approaches targeting human kappa light-chain diseases, Published online: 29 March 2019; doi:10.1038/s41434-019-0070-yA novel xenograft mouse model for testing approaches targeting human kappa light-chain diseases (Source: Gene Therapy)
Source: Gene Therapy - March 29, 2019 Category: Genetics & Stem Cells Authors: Xun Ma Ping Zhou Adin Kugelmass Denis Toskic Melissa Warner Lisa Lee Terry Fogaren Amandeep Godara Ming Wang Yamin Li Liu Yang Qiaobing Xu Raymond L. Comenzo Source Type: research

Safe and neuroprotective vectors for long-term traumatic brain injury gene therapy
Safe and neuroprotective vectors for long-term traumatic brain injury gene therapy, Published online: 29 March 2019; doi:10.1038/s41434-019-0073-8Safe and neuroprotective vectors for long-term traumatic brain injury gene therapy (Source: Gene Therapy)
Source: Gene Therapy - March 29, 2019 Category: Genetics & Stem Cells Authors: Daniela Blanco-Ocampo Fabio Andr és Cawen Luis Angel Álamo-Pindado Mar ía Luciana Negro-Demontel Hugo Peluffo Source Type: research

Combination of cabazitaxel and p53 gene therapy abolishes prostate carcinoma tumor growth
Combination of cabazitaxel and p53 gene therapy abolishes prostate carcinoma tumor growth, Published online: 29 March 2019; doi:10.1038/s41434-019-0071-xCombination of cabazitaxel and p53 gene therapy abolishes prostate carcinoma tumor growth (Source: Gene Therapy)
Source: Gene Therapy - March 29, 2019 Category: Genetics & Stem Cells Authors: Rodrigo Esaki Tamura Marlous G. Lana Eugenia Costanzi-Strauss Bryan E. Strauss Source Type: research

Stability of the adeno-associated virus 8 reference standard material
Stability of the adeno-associated virus 8 reference standard material, Published online: 29 March 2019; doi:10.1038/s41434-019-0072-9Stability of the adeno-associated virus 8 reference standard material (Source: Gene Therapy)
Source: Gene Therapy - March 29, 2019 Category: Genetics & Stem Cells Authors: Magalie Penaud-Budloo Fr édéric Broucque Katell Harrouet Mohammed Bouzelha Sylvie Saleun Sandy Douthe Susan D ’Costa Sushma Ogram Oumeya Adjali V éronique Blouin Martin Lock Richard O. Snyder Eduard Ayuso Source Type: research

A novel approach for assessment of prostate cancer aggressiveness using survivin-driven tumour-activatable minicircles
A novel approach for assessment of prostate cancer aggressiveness using survivin-driven tumour-activatable minicircles, Published online: 13 March 2019; doi:10.1038/s41434-019-0067-6A novel approach for assessment of prostate cancer aggressiveness using survivin-driven tumour-activatable minicircles (Source: Gene Therapy)
Source: Gene Therapy - March 13, 2019 Category: Genetics & Stem Cells Authors: TianDuo Wang Yuanxin Chen John. A. Ronald Source Type: research

Combination of cytokine-enhanced vaccine and chemo-gene therapy as surgery adjuvant treatments for spontaneous canine melanoma
Combination of cytokine-enhanced vaccine and chemo-gene therapy as surgery adjuvant treatments for spontaneous canine melanoma, Published online: 11 March 2019; doi:10.1038/s41434-019-0066-7Combination of cytokine-enhanced vaccine and chemo-gene therapy as surgery adjuvant treatments for spontaneous canine melanoma (Source: Gene Therapy)
Source: Gene Therapy - March 11, 2019 Category: Genetics & Stem Cells Authors: Liliana M. E. Finocchiaro Lucrecia Agnetti Chiara Fondello Gerardo C. Glikin Source Type: research

Gene and cell therapy on the acquisition and relapse-like binge drinking in a model of alcoholism: translational options
Gene and cell therapy on the acquisition and relapse-like binge drinking in a model of alcoholism: translational options, Published online: 28 February 2019; doi:10.1038/s41434-019-0064-9Gene and cell therapy on the acquisition and relapse-like binge drinking in a model of alcoholism: translational options (Source: Gene Therapy)
Source: Gene Therapy - February 28, 2019 Category: Genetics & Stem Cells Authors: Yedy Israel Mar ía Elena Quintanilla Fernando Ezquer Paola Morales Mario Rivera-Meza Eduardo Karahanian Marcelo Ezquer Mario Herrera-Marschitz Source Type: research

ILK promotes survival and self-renewal of hypoxic MSCs via the activation of lncTCF7-Wnt pathway induced by IL-6/STAT3 signaling
ILK promotes survival and self-renewal of hypoxic MSCs via the activation of lncTCF7-Wnt pathway induced by IL-6/STAT3 signaling, Published online: 27 February 2019; doi:10.1038/s41434-018-0055-2ILK promotes survival and self-renewal of hypoxic MSCs via the activation of lncTCF7-Wnt pathway induced by IL-6/STAT3 signaling (Source: Gene Therapy)
Source: Gene Therapy - February 27, 2019 Category: Genetics & Stem Cells Authors: Qing Mao Xiu-Lin Liang Yu-Fu Wu Yi-Heng Pang Xiao-Jun Zhao Yong-Xiang Lu Source Type: research

Regulatable adenovector harboring the GFP and Yamanaka genes for implementing regenerative medicine in the brain
Regulatable adenovector harboring the GFP and Yamanaka genes for implementing regenerative medicine in the brain, Published online: 15 February 2019; doi:10.1038/s41434-019-0063-xRegulatable adenovector harboring the GFP and Yamanaka genes for implementing regenerative medicine in the brain (Source: Gene Therapy)
Source: Gene Therapy - February 15, 2019 Category: Genetics & Stem Cells Authors: Marianne Lehmann Martina Canatelli-Mallat Priscila Chiavellini Gustavo R. Morel Paula C. Reggiani Claudia B. Here ñú Rodolfo G. Goya Source Type: research

scFv6.C4 DNA vaccine with fragment C of Tetanus toxin increases protective immunity against CEA-expressing tumor
scFv6.C4 DNA vaccine with fragment C of Tetanus toxin increases protective immunity against CEA-expressing tumor, Published online: 15 February 2019; doi:10.1038/s41434-019-0062-yscFv6.C4 DNA vaccine with fragment C of Tetanus toxin increases protective immunity against CEA-expressing tumor (Source: Gene Therapy)
Source: Gene Therapy - February 15, 2019 Category: Genetics & Stem Cells Authors: Bianca Ferrarini Zanetti Camila Pontes Ferreira Jos é Ronnie Carvalho de Vasconcelos Sang Won Han Source Type: research

Measles vector as a multiple genes delivery platform facilitating iPSC reprogramming
Measles vector as a multiple genes delivery platform facilitating iPSC reprogramming, Published online: 04 February 2019; doi:10.1038/s41434-019-0058-7Measles vector as a multiple genes delivery platform facilitating iPSC reprogramming (Source: Gene Therapy)
Source: Gene Therapy - February 4, 2019 Category: Genetics & Stem Cells Authors: Qi Wang Alanna Vossen Yasuhiro Ikeda Patricia Devaux Source Type: research

Helper-dependent adenovirus-mediated gene transfer of a secreted LDL receptor/transferrin chimeric protein reduces aortic atherosclerosis in LDL receptor-deficient mice
Helper-dependent adenovirus-mediated gene transfer of a secreted LDL receptor/transferrin chimeric protein reduces aortic atherosclerosis in LDL receptor-deficient mice, Published online: 30 January 2019; doi:10.1038/s41434-019-0061-zHelper-dependent adenovirus-mediated gene transfer of a secreted LDL receptor/transferrin chimeric protein reduces aortic atherosclerosis in LDL receptor-deficient mice (Source: Gene Therapy)
Source: Gene Therapy - January 30, 2019 Category: Genetics & Stem Cells Authors: Eleonora Leggiero Giuseppe Labruna Laura Iaffaldano Barbara Lombardo Adelaide Greco Dario Fiorenza Matteo Gramanzini Donatella Montanaro Alfonso Baldi Vincenzo Cerullo Lucia Sacchetti Lucio Pastore Source Type: research

Safety and efficacy evaluations of an adeno-associated virus variant for preparing IL10-secreting human neural stem cell-based therapeutics
Safety and efficacy evaluations of an adeno-associated virus variant for preparing IL10-secreting human neural stem cell-based therapeutics, Published online: 28 January 2019; doi:10.1038/s41434-019-0057-8Safety and efficacy evaluations of an adeno-associated virus variant for preparing IL10-secreting human neural stem cell-based therapeutics (Source: Gene Therapy)
Source: Gene Therapy - January 28, 2019 Category: Genetics & Stem Cells Authors: Mira Cho Kwangsoo Jung Seung-Hyun Kim Il-Sun Kim Miri Kim Mikyung Shin Haeshin Lee Kook In Park Jae-Hyung Jang Source Type: research

Factors governing the transduction efficiency of adeno-associated virus in the retinal ganglion cells following intravitreal injection
Factors governing the transduction efficiency of adeno-associated virus in the retinal ganglion cells following intravitreal injection, Published online: 28 January 2019; doi:10.1038/s41434-019-0060-0Factors governing the transduction efficiency of adeno-associated virus in the retinal ganglion cells following intravitreal injection (Source: Gene Therapy)
Source: Gene Therapy - January 28, 2019 Category: Genetics & Stem Cells Authors: Xu Cao Jasmine Yung Heather Mak Christopher K. S. Leung Source Type: research

Dual-targeted NIS polyplexes—a theranostic strategy toward tumors with heterogeneous receptor expression
Dual-targeted NIS polyplexes—a theranostic strategy toward tumors with heterogeneous receptor expressionDual-targeted NIS polyplexes—a theranostic strategy toward tumors with heterogeneous receptor expression, Published online: 25 January 2019; doi:10.1038/s41434-019-0059-6Dual-targeted NIS polyplexes—a theranostic strategy toward tumors with heterogeneous receptor expression (Source: Gene Therapy)
Source: Gene Therapy - January 25, 2019 Category: Genetics & Stem Cells Authors: Sarah Urnauer Kathrin A. Schmohl Mariella Tutter Christina Schug Nathalie Schwenk Stephan Morys Sibylle Ziegler Peter Bartenstein Dirk-Andr é Clevert Ernst Wagner Christine Spitzweg Source Type: research

Production of lentiviral vectors using novel, enzymatically produced, linear DNA
Production of lentiviral vectors using novel, enzymatically produced, linear DNA, Published online: 14 January 2019; doi:10.1038/s41434-018-0056-1Production of lentiviral vectors using novel, enzymatically produced, linear DNA (Source: Gene Therapy)
Source: Gene Therapy - January 14, 2019 Category: Genetics & Stem Cells Authors: Rajvinder Karda John R. Counsell Kinga Karbowniczek Lisa J. Caproni John P. Tite Simon N. Waddington Source Type: research

Correction: Epistasis between Pax6Sey and genetic background reinforces the value of defined hybrid mouse models for therapeutic trials
Correction: Epistasis between Pax6Sey and genetic background reinforces the value of defined hybrid mouse models for therapeutic trials, Published online: 02 January 2019; doi:10.1038/s41434-018-0054-3Correction: Epistasis between Pax6Sey and genetic background reinforces the value of defined hybrid mouse models for therapeutic trials (Source: Gene Therapy)
Source: Gene Therapy - January 2, 2019 Category: Genetics & Stem Cells Authors: Jack W. Hickmott Uvini Gunawardane Kimberly Jensen Andrea J. Korecki Elizabeth M. Simpson Source Type: research

Histone deacetylase inhibitors reactivate silenced transgene in vivo
Histone deacetylase inhibitors reactivate silenced transgene in vivo, Published online: 11 December 2018; doi:10.1038/s41434-018-0053-4Histone deacetylase inhibitors reactivate silenced transgene in vivo (Source: Gene Therapy)
Source: Gene Therapy - December 11, 2018 Category: Genetics & Stem Cells Authors: Chunbo Zhang Guisheng Zhang Dexi Liu Source Type: research

GDNF-mediated rescue of the nigrostriatal system depends on the degree of degeneration
GDNF-mediated rescue of the nigrostriatal system depends on the degree of degeneration, Published online: 07 December 2018; doi:10.1038/s41434-018-0049-0GDNF-mediated rescue of the nigrostriatal system depends on the degree of degeneration (Source: Gene Therapy)
Source: Gene Therapy - December 7, 2018 Category: Genetics & Stem Cells Authors: Luis Quintino Martino Avallone Emil Br ännstrom Patrick Kavanagh Marcus Lockowandt Patricia Garcia Jare ño Ludivine S Breger Cecilia Lundberg Source Type: research

Immunosuppression overcomes insulin- and vector-specific immune responses that limit efficacy of AAV2/8-mediated insulin gene therapy in NOD mice
Immunosuppression overcomes insulin- and vector-specific immune responses that limit efficacy of AAV2/8-mediated insulin gene therapy in NOD mice, Published online: 04 December 2018; doi:10.1038/s41434-018-0052-5Immunosuppression overcomes insulin- and vector-specific immune responses that limit efficacy of AAV2/8-mediated insulin gene therapy in NOD mice (Source: Gene Therapy)
Source: Gene Therapy - December 4, 2018 Category: Genetics & Stem Cells Authors: Asha Recino Shu Uin Gan Kian Chuan Sia Yvonne Sawyer Jenny Trendell Richard Kay Fiona M. Gribble Frank Reimann Rob Foale Maria Notaridou Nick Holmes Andrew Lever Kok Onn Lee Amit Nathwani Anne Cooke Roy Calne Maja Wallberg Source Type: research

Reviewer recognition
Reviewer recognition, Published online: 03 December 2018; doi:10.1038/s41434-018-0048-1Reviewer recognition (Source: Gene Therapy)
Source: Gene Therapy - December 3, 2018 Category: Genetics & Stem Cells Source Type: research

Unilateral ex vivo gene therapy by GDNF in epileptic rats
Unilateral ex vivo gene therapy by GDNF in epileptic rats, Published online: 21 November 2018; doi:10.1038/s41434-018-0050-7Unilateral ex vivo gene therapy by GDNF in epileptic rats (Source: Gene Therapy)
Source: Gene Therapy - November 21, 2018 Category: Genetics & Stem Cells Authors: Avtandil Nanobashvili Esbj örn Melin Dwaine Emerich Jens Torn øe Michele Simonato Lars Wahlberg Merab Kokaia Source Type: research

HIV infection alters the human epigenetic landscape
HIV infection alters the human epigenetic landscape, Published online: 15 November 2018; doi:10.1038/s41434-018-0051-6HIV infection alters the human epigenetic landscape (Source: Gene Therapy)
Source: Gene Therapy - November 15, 2018 Category: Genetics & Stem Cells Authors: Lei Chen Shiqi Zhang Xiaoyong Pan XiaoHua Hu Yu-Hang Zhang Fei Yuan Tao Huang Yu-Dong Cai Source Type: research

Osteoinduction within BMP-2 transduced muscle tissue fragments with and without a fascia layer: implications for bone tissue engineering
Osteoinduction within BMP-2 transduced muscle tissue fragments with and without a fascia layer: implications for bone tissue engineering, Published online: 27 October 2018; doi:10.1038/s41434-018-0047-2Osteoinduction within BMP-2 transduced muscle tissue fragments with and without a fascia layer: implications for bone tissue engineering (Source: Gene Therapy)
Source: Gene Therapy - October 27, 2018 Category: Genetics & Stem Cells Authors: Bin Ren Volker M. Betz Christian Thirion Michael Salomon Volkmar Jansson Peter E. M üller Oliver B. Betz Source Type: research