Dysphagia Is an Underrecognized Risk Factor for Viral Pneumonia Severity
This study showed that a pre-existing diagnosis of dysphagia was independently associated with COVID-19 severity in adults ≥50 years of age. (Source: Dysphagia)
Source: Dysphagia - April 27, 2024 Category: Speech-Language Pathology Source Type: research
AAV-vectored expression of monospecific or bispecific monoclonal antibodies protects mice from lethal Pseudomonas aeruginosa pneumonia
Gene Therapy, Published online: 27 April 2024; doi:10.1038/s41434-024-00453-1AAV-vectored expression of monospecific or bispecific monoclonal antibodies protects mice from lethal Pseudomonas aeruginosa pneumonia (Source: Gene Therapy)
Source: Gene Therapy - April 27, 2024 Category: Genetics & Stem Cells Authors: Jordyn A. Lopes Nicole E. Garnier Yanlong Pei Jacob G. E. Yates Elena S. B. Campbell Melanie M. Goens Madison E. Hughes Amira D. Rghei Brenna A. Y. Stevens Matthew M. Guilleman Brad Thompson Cezar M. Khursigara Leonardo Susta Sarah K. Wootton Source Type: research
TRIM27-Induced Protective Autophagy: A Novel Therapeutic Approach for Pneumonia
CONCLUSION: The induction of TRIM27 overexpression emerges as a potential and effective pneumonia treatment. The underlying mechanism may involve inducing protective autophagy, thereby reducing oxidative stress and cell pyroptosis.PMID:38665029 | DOI:10.24976/Discov.Med.202436183.76 (Source: Discovery Medicine)
Source: Discovery Medicine - April 26, 2024 Category: Research Authors: Yajiao Pang Hongrong Wang Qiaoyi Xie Tingting Ma Source Type: research
Aspergillus Endogenous Endophthalmitis as a Clue to Identifying a Delayed Lumbosacral Osteomyelitis
CONCLUSION: This case highlights the atypical progression of Aspergillus-induced endogenous endophthalmitis to delayed lumbosacral osteomyelitis in an immunocompetent individual. It highlights the crucial role of a meticulous medical history examination and interdisciplinary collaboration in diagnosing and managing diseases, especially in cases with atypical presentations.PMID:38668792 | DOI:10.1080/09273948.2024.2344704 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - April 26, 2024 Category: Allergy & Immunology Authors: Muhammed Altinisik Yeliz Delibay Akgun Mustafa Erdogan Azzam Faiz Mutawakkil Horu Gazi Source Type: research
TRIM27-Induced Protective Autophagy: A Novel Therapeutic Approach for Pneumonia
CONCLUSION: The induction of TRIM27 overexpression emerges as a potential and effective pneumonia treatment. The underlying mechanism may involve inducing protective autophagy, thereby reducing oxidative stress and cell pyroptosis.PMID:38665029 | DOI:10.24976/Discov.Med.202436183.76 (Source: Discovery Medicine)
Source: Discovery Medicine - April 26, 2024 Category: Research Authors: Yajiao Pang Hongrong Wang Qiaoyi Xie Tingting Ma Source Type: research
Aspergillus Endogenous Endophthalmitis as a Clue to Identifying a Delayed Lumbosacral Osteomyelitis
CONCLUSION: This case highlights the atypical progression of Aspergillus-induced endogenous endophthalmitis to delayed lumbosacral osteomyelitis in an immunocompetent individual. It highlights the crucial role of a meticulous medical history examination and interdisciplinary collaboration in diagnosing and managing diseases, especially in cases with atypical presentations.PMID:38668792 | DOI:10.1080/09273948.2024.2344704 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - April 26, 2024 Category: Allergy & Immunology Authors: Muhammed Altinisik Yeliz Delibay Akgun Mustafa Erdogan Azzam Faiz Mutawakkil Horu Gazi Source Type: research
TRIM27-Induced Protective Autophagy: A Novel Therapeutic Approach for Pneumonia
CONCLUSION: The induction of TRIM27 overexpression emerges as a potential and effective pneumonia treatment. The underlying mechanism may involve inducing protective autophagy, thereby reducing oxidative stress and cell pyroptosis.PMID:38665029 | DOI:10.24976/Discov.Med.202436183.76 (Source: Discovery Medicine)
Source: Discovery Medicine - April 26, 2024 Category: Research Authors: Yajiao Pang Hongrong Wang Qiaoyi Xie Tingting Ma Source Type: research
Novel Patterns in High-Resolution Computed Tomography in Whipple Pneumonia
We report a series of 3 cases in China that showed a novel pattern of movable infiltrates and upper lung micronodules. After treatment, the 3 patients recovered, and lung infiltrates resolved.PMID:38666708 | DOI:10.3201/eid3005.231130 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - April 26, 2024 Category: Infectious Diseases Authors: Hui Li Jiajia Wu Xiaojun Mai Wan Zeng Shuping Cai Xiuji Huang Chunxia Zhou Jin Li Qin Jiang Chunliu Lai Canmao Xie Source Type: research
Wireless breathable face mask sensor for spatiotemporal 2D respiration profiling and respiratory diagnosis
In this study, we introduced an air-permeable, stretchable, and a pixelated pressure sensor that can be integrated into a commercial face mask. The mask sensor showed a strain-independent pressure-sensing performance, providing 2D pressure profiles for exhalation and inhalation. Real-time 2D respiration profiles could monitor various respiratory behaviors, such as oral/nasal breathing, clogged nose, out-of-breath, and coughing. Furthermore, they could detect respiratory diseases, such as rhinitis, sleep apnea, and pneumonia. The 2D respiratory profiling mask sensor is expected to be employed for remote respiration monitori...
Source: Biomaterials - April 26, 2024 Category: Materials Science Authors: Jaehyun Kim Heesung Roh Sungmin Moon Cheonhoo Jeon Seunggoo Baek Woosung Cho Jae-Yoon Sim Unyong Jeong Source Type: research
TRIM27-Induced Protective Autophagy: A Novel Therapeutic Approach for Pneumonia
CONCLUSION: The induction of TRIM27 overexpression emerges as a potential and effective pneumonia treatment. The underlying mechanism may involve inducing protective autophagy, thereby reducing oxidative stress and cell pyroptosis.PMID:38665029 | DOI:10.24976/Discov.Med.202436183.76 (Source: Discovery Medicine)
Source: Discovery Medicine - April 26, 2024 Category: Research Authors: Yajiao Pang Hongrong Wang Qiaoyi Xie Tingting Ma Source Type: research
Aspergillus Endogenous Endophthalmitis as a Clue to Identifying a Delayed Lumbosacral Osteomyelitis
CONCLUSION: This case highlights the atypical progression of Aspergillus-induced endogenous endophthalmitis to delayed lumbosacral osteomyelitis in an immunocompetent individual. It highlights the crucial role of a meticulous medical history examination and interdisciplinary collaboration in diagnosing and managing diseases, especially in cases with atypical presentations.PMID:38668792 | DOI:10.1080/09273948.2024.2344704 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - April 26, 2024 Category: Allergy & Immunology Authors: Muhammed Altinisik Yeliz Delibay Akgun Mustafa Erdogan Azzam Faiz Mutawakkil Horu Gazi Source Type: research
Pulmonary function and chest CT abnormalities 3 months after discharge from COVID-19, 2020-2021: A nation-wide multicenter prospective cohort study from the Japanese respiratory society
CONCLUSION: We reported a comprehensive analysis of post-COVID-19 condition, pulmonary function, and chest CT abnormalities in Japanese patients with COVID-19. The findings of this study will serve as valuable reference data for future post-COVID-19 condition research in Japan.PMID:38669898 | DOI:10.1016/j.resinv.2024.02.009 (Source: Respiratory Care)
Source: Respiratory Care - April 26, 2024 Category: Respiratory Medicine Authors: Hirofumi Kamata Kazufumi Takamatsu Koichi Fukunaga Shotaro Chubachi Kensuke Nakagawara Ho Namkoong Hideki Terai Katsushi Tanaka Susumu Sato Eri Hagiwara Reoto Takei Yasuhiro Kondoh Takahiro Takazono Midori Hashimoto Sadatomo Tasaka Takashi Ohrui Yoshinori Source Type: research
Novel Patterns in High-Resolution Computed Tomography in Whipple Pneumonia
We report a series of 3 cases in China that showed a novel pattern of movable infiltrates and upper lung micronodules. After treatment, the 3 patients recovered, and lung infiltrates resolved.PMID:38666708 | DOI:10.3201/eid3005.231130 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - April 26, 2024 Category: Infectious Diseases Authors: Hui Li Jiajia Wu Xiaojun Mai Wan Zeng Shuping Cai Xiuji Huang Chunxia Zhou Jin Li Qin Jiang Chunliu Lai Canmao Xie Source Type: research
Effect of acyclovir therapy on the outcome of mechanically ventilated patients with lower respiratory tract infection and detection of herpes simplex virus in bronchoalveolar lavage: protocol for a multicentre, randomised controlled trial (HerpMV)
BMJ Open. 2024 Apr 25;14(4):e082512. doi: 10.1136/bmjopen-2023-082512.ABSTRACTINTRODUCTION: Herpes simplex virus (HSV) is frequently detected in the respiratory tract of mechanically ventilated patients and is associated with a worse outcome. The aim of this study is to determine whether antiviral therapy in HSV-positive patients improves outcome.METHODS AND ANALYSIS: Prospective, multicentre, open-label, randomised, controlled trial in parallel-group design. Adult, mechanically ventilated patients with pneumonia and HSV type 1 detected in bronchoalveolar lavage (≥105 copies/mL) are eligible for participation and will be...
Source: Herpes - April 26, 2024 Category: Infectious Diseases Authors: Stefan Hagel Nicole Brillinger Sebastian Decker Maria Deja Christian Ertmer Sandra Fiedler Philipp Franken Markus Heim Markus A Weigand Alexander Zarbock Mathias W Pletz SepNet Critical Care Trials Group Source Type: research
Wireless breathable face mask sensor for spatiotemporal 2D respiration profiling and respiratory diagnosis
In this study, we introduced an air-permeable, stretchable, and a pixelated pressure sensor that can be integrated into a commercial face mask. The mask sensor showed a strain-independent pressure-sensing performance, providing 2D pressure profiles for exhalation and inhalation. Real-time 2D respiration profiles could monitor various respiratory behaviors, such as oral/nasal breathing, clogged nose, out-of-breath, and coughing. Furthermore, they could detect respiratory diseases, such as rhinitis, sleep apnea, and pneumonia. The 2D respiratory profiling mask sensor is expected to be employed for remote respiration monitori...
Source: Biomaterials - April 26, 2024 Category: Materials Science Authors: Jaehyun Kim Heesung Roh Sungmin Moon Cheonhoo Jeon Seunggoo Baek Woosung Cho Jae-Yoon Sim Unyong Jeong Source Type: research
