Understanding Lactatemia in Human Sepsis: Potential Impact for Early Management.
CONCLUSIONS: Hyperlactatemia is powerfully correlated with severity of sepsis and it is caused more frequently by impaired tissue oxygen utilization, rather than by impaired oxygen transport. Concomitant acidemia was only observed in the presence of renal dysfunction, as rapidly detected by alactic base excess. The current strategy of fluid resuscitation could be modified according to the origin of excess lactate. PMID: 30985210 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 15, 2019 Category: Respiratory Medicine Authors: Gattinoni L, Vasques F, Camporota L, Meessen J, Romitti F, Pasticci I, Duscio E, Vassalli F, Forni LG, Payen D, Cressoni M, Zanella A, Latini R, Quintel M, Marini JJ Tags: Am J Respir Crit Care Med Source Type: research

Acute Treatment of Pulmonary Embolism: Part 2.
PMID: 30985211 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 15, 2019 Category: Respiratory Medicine Authors: Rali P, Gandhi V, Sockrider M Tags: Am J Respir Crit Care Med Source Type: research

Design of IPF Clinical Trials in the Era of Approved Therapies.
Abstract The approval of nintedanib and pirfenidone for treatment of idiopathic pulmonary fibrosis has introduced complexity into the design of clinical trials for new drugs on many levels. Placebo-controlled trials excluding background therapy may have issues with feasibility. Those that allow background therapy must consider the possibility of drug-drug interactions with existing therapies, as well as the narrower therapeutic window available to demonstrate incremental slowing of lung function decline with a new agent. While many trial participants will already be on background therapy, a significant number will...
Source: American Journal of Respiratory and Critical Care Medicine - April 15, 2019 Category: Respiratory Medicine Authors: Kaner RJ, Bajwa EK, El-Amine M, Gorina E, Gupta R, Lazarus HM, Luckhardt TR, Mouded M, Posada K, Richeldi L, Stauffer J, Tutuncu A, Martinez FJ Tags: Am J Respir Crit Care Med Source Type: research

Zooming into the Matrix: Using Non-linear Microscopy to Visualise Collagen Remodelling in Asthmatic Airways.
PMID: 30985216 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 15, 2019 Category: Respiratory Medicine Authors: Snelgrove RJ, Patel DF Tags: Am J Respir Crit Care Med Source Type: research

Familial Pulmonary Fibrosis and Hermansky-Pudlak Syndrome Rare Missense Mutations In Context.
PMID: 30985222 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 15, 2019 Category: Respiratory Medicine Authors: Stearman RS, Cornelius AR, Young LR, Conklin DS, Mickler EA, Lu X, Hara N, Fettig LM, Phang TL, Geraci MW Tags: Am J Respir Crit Care Med Source Type: research

Recommended Reading from the Children's Hospital of Philadelphia Fellows.
PMID: 30986091 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 15, 2019 Category: Respiratory Medicine Authors: Vazquez-Garcia GA, Fierro JL, Quinlan CM, Tapia IE Tags: Am J Respir Crit Care Med Source Type: research

Azithromycin, the Holy Grail to Prevent Exacerbations in Chronic Respiratory Disease.
PMID: 30986361 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 15, 2019 Category: Respiratory Medicine Authors: Welte T Tags: Am J Respir Crit Care Med Source Type: research

Particle Depletion Does Not Remediate Acute Effects of Traffic-Related Air Pollution and Allergen: A Randomized, Double-Blinded Crossover Study.
CONCLUSIONS: Co-exposure to diesel exhaust and allergen impaired lung function, which was worse after particle-depletion (which increased NO2). Thus, particulates are not necessarily the sole or main culprit responsible for all harmful effects of diesel exhaust. Policies and technologies aimed at protecting public health should be scrutinized in that regard. PMID: 30974969 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 12, 2019 Category: Respiratory Medicine Authors: Wooding DJ, Hyung Ryu M, Hüls A, Lee AD, Lin DTS, Rider CF, Yuen ACY, Carlsten C Tags: Am J Respir Crit Care Med Source Type: research

Unique Effect of Aspirin Therapy on Biomarkers in Aspirin-Exacerbated Respiratory Disease: A Prospective Trial.
Abstract RATIONALE: Daily high-dose aspirin therapy benefits many patients with aspirin-exacerbated respiratory disease but provides no benefit for aspirin-tolerant asthmatics. Type 2 inflammation characterizes aspirin-exacerbated respiratory disease. OBJECTIVE: We sought to determine whether high-dose aspirin therapy changes biomarkers of type 2 inflammation in aspirin-exacerbated respiratory disease. METHODS: Forty-two subjects with aspirin-exacerbated respiratory disease underwent an aspirin desensitization and were placed on high-dose aspirin (1300 mg daily). Fifteen aspirin-tolerant asthmatics were ...
Source: American Journal of Respiratory and Critical Care Medicine - April 12, 2019 Category: Respiratory Medicine Authors: Cahill KN, Cui J, Kothari P, Murphy K, Raby BA, Singer J, Israel E, Boyce JA, Laidlaw TM Tags: Am J Respir Crit Care Med Source Type: research

Loss of Microbial Topography Precedes Infection in Infants.
PMID: 30978299 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 12, 2019 Category: Respiratory Medicine Authors: Surette MG, Bowdish DME Tags: Am J Respir Crit Care Med Source Type: research

Video Telehealth Pulmonary Rehabilitation Intervention In COPD Reduces 30-day Readmissions.
PMID: 30978302 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 12, 2019 Category: Respiratory Medicine Authors: Bhatt SP, Patel SB, Anderson EM, Baugh D, Givens T, Schumann C, Sanders JG, Windham ST, Cutter GR, Dransfield MT Tags: Am J Respir Crit Care Med Source Type: research

A lncRNA Links TGF- β Signaling in Lung Fibrosis.
A lncRNA Links TGF-β Signaling in Lung Fibrosis. Am J Respir Crit Care Med. 2019 Apr 11;: Authors: Jiang D, Liang J PMID: 30973751 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 11, 2019 Category: Respiratory Medicine Authors: Jiang D, Liang J Tags: Am J Respir Crit Care Med Source Type: research

A Novel Peptide for Immunomodulation in Pulmonary Arterial Hypertension.
PMID: 30973752 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 11, 2019 Category: Respiratory Medicine Authors: Grinnan D, Farkas L Tags: Am J Respir Crit Care Med Source Type: research

XBP1S Regulates MUC5B in a Promoter Variant-Dependent Pathway in IPF Airway Epithelia.
CONCLUSION: A positive feedback bistable ERN2-XBP1S pathway regulates MUC5B-dominated mucus obstruction in IPF, providing a UPR-dependent mechanism linking the MUC5B promoter rs35705950 polymorphism with IPF pathogenesis. Inhibiting ERN2-dependent pathways/elements may provide a therapeutic option for IPF. PMID: 30973754 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 11, 2019 Category: Respiratory Medicine Authors: Chen G, Ribeiro CMP, Sun L, Okuda K, Kato T, Gilmore RC, Martino MB, Dang H, Abzhanova A, Lin JM, Hull-Ryde EA, Volmer AS, Randell SH, Livraghi-Butrico A, Deng Y, Scherer PE, Stripp BR, O'Neal WK, Boucher RC Tags: Am J Respir Crit Care Med Source Type: research

The Mortality Burden of Idiopathic Pulmonary Fibrosis in the United Kingdom.
PMID: 30973756 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 11, 2019 Category: Respiratory Medicine Authors: Navaratnam V, Hubbard RB Tags: Am J Respir Crit Care Med Source Type: research

Exhaled Volatile Organic Compounds are Able to Discriminate between Neutrophilic and Eosinophilic Asthma.
CONCLUSION: Our study is the first attempt to characterize VOCs according to sputum granulocytic profile in a large population of asthmatics and provide surrogate markers for neutrophilic asthma. PMID: 30973757 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 11, 2019 Category: Respiratory Medicine Authors: Schleich FN, Zanella D, Stefanuto PH, Bessonov K, Smolinska A, Dallinga JW, Henket M, Paulus V, Guissard F, Graff S, Moermans C, Wouters EFM, Van Steen K, van Schooten FJ, Focant JF, Louis R Tags: Am J Respir Crit Care Med Source Type: research

Broncho-endoscopic Repair of Tracheoesophageal Fistula.
PMID: 30973758 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 11, 2019 Category: Respiratory Medicine Authors: Mozer AB, Michel E, Gillespie C, Bharat A Tags: Am J Respir Crit Care Med Source Type: research

The Long Non-Coding RNA DNM3OS is a Reservoir of FibromiRs with Major Functions in Lung Fibroblast Response to TGF- β and Pulmonary Fibrosis.
CONCLUSION: Pharmacological approaches aiming at interfering with DNM3OS may represent new effective therapeutic strategies in IPF. PMID: 30964696 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 9, 2019 Category: Respiratory Medicine Authors: Savary G, Dewaeles E, Diazzi S, Buscot M, Nottet N, Fassy J, Courcot E, Henaoui IS, Lemaire J, Martis N, Van der Hauwaert C, Pons N, Magnone V, Leroy S, Hofman V, Plantier L, Lebrigand K, Paquet A, Lino Cardenas CL, Vassaux G, Hofman P, Günther A, Cresta Tags: Am J Respir Crit Care Med Source Type: research

The Biological Effects of Double-Dose Alpha-1 Antitrypsin Augmentation Therapy: A Pilot Study.
CONCLUSION: Subjects with AATD on SD augmentation therapy still exhibit inflammation, protease activity and elastin degradation that can be further improved by normalizing AAT levels. Higher AAT dosing than currently recommended may lead to enhanced clinical benefits and should be explored further. Clinical trial registration available at www.clinicaltrials.gov, ID NCT01669421. PMID: 30965011 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 9, 2019 Category: Respiratory Medicine Authors: Campos MA, Geraghty P, Holt G, Mendes E, Newby PR, Ma S, Luna-Diaz LV, Turino GM, Stockley RA Tags: Am J Respir Crit Care Med Source Type: research

Synergistic Association of House Endotoxin Exposure and Ambient Air Pollution with Asthma Outcomes.
CONCLUSIONS: Co-exposure to elevated levels of residential endotoxin and ambient PM2.5 in all participants and NO2 in children is synergistically associated with increased ER visits for asthma. Therefore, decreasing exposure to both endotoxin and air pollution may help reduce asthma morbidity. PMID: 30965018 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 9, 2019 Category: Respiratory Medicine Authors: Mendy A, Wilkerson J, Salo PM, Weir CH, Feinstein L, Zeldin DC, Thorne PS Tags: Am J Respir Crit Care Med Source Type: research

Mycobacterium Avium Complex Diversity within Lung Disease as Revealed by Whole Genome Sequencing.
PMID: 30965019 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 9, 2019 Category: Respiratory Medicine Authors: Operario DJ, Pholwat S, Koeppel AF, Prorock A, Bao Y, Sol-Church K, Scheurenbrand M, Poulter M, Turner S, Parikh HI, Mathers A, Houpt ER Tags: Am J Respir Crit Care Med Source Type: research

Indoor Exposure and Sensitization to Formaldehyde among Inner-City Children with Increased Risk of Asthma and Rhinitis.
PMID: 30958969 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 8, 2019 Category: Respiratory Medicine Authors: Yon DK, Hwang S, Lee SW, Jee HM, Sheen YH, Kim JH, Lim DH, Han MY Tags: Am J Respir Crit Care Med Source Type: research

Update in Critical Care / ARDS 2018.
PMID: 30958975 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 8, 2019 Category: Respiratory Medicine Authors: Douglas IS, Bednash JS, Fein DG, Mallampalli RK, Mansoori J, Gershengorn HB Tags: Am J Respir Crit Care Med Source Type: research

Update in Chronic Obstructive Pulmonary Disease 2018.
PMID: 30958976 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 8, 2019 Category: Respiratory Medicine Authors: Labaki WW, Kimmig LM, Mutlu GM, Han MK, Bhatt SP Tags: Am J Respir Crit Care Med Source Type: research

Reply to: Vitamin C to Pregnant Smokers and Infant Airway Function: Missing the Wood for the Trees?
PMID: 30950629 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 5, 2019 Category: Respiratory Medicine Authors: McEvoy CT, Tepper RS, Gonzales D, Spindel ER, Morris CD Tags: Am J Respir Crit Care Med Source Type: research

Vitamin C to Pregnant Smokers and Infant Airway Function: Missing the Wood for the Trees?
PMID: 30950632 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 5, 2019 Category: Respiratory Medicine Authors: Braillon A Tags: Am J Respir Crit Care Med Source Type: research

Defective Fibrillar Collagen Organization by Fibroblasts Contributes to Airway Remodeling in Asthma.
CONCLUSIONS: NLOM imaging enabled the structural assessment of the ECM, and the data suggest that airway remodeling in asthma involves the progressive accumulation of disorganized fibrillar collagen by airway fibroblasts. This study highlights the future potential clinical application of NLOM to assess airway remodeling in vivo. PMID: 30950644 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 5, 2019 Category: Respiratory Medicine Authors: Mostaço-Guidolin LB, Osei ET, Ullah J, Hajimohammadi S, Fouadi M, Li X, Li V, Shaheen F, Yang CX, Chu F, Cole DJ, Brandsma CA, Heijink IH, Maksym GN, Walker D, Hackett TL Tags: Am J Respir Crit Care Med Source Type: research

The Effect of Aclidinium on Symptoms Including Cough in COPD: A Phase IV, DoubleBlind, Placebo-Controlled, Parallel-Group Study.
PMID: 30951372 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 5, 2019 Category: Respiratory Medicine Authors: Smith JA, McGarvey L, Morice AH, Birring SS, Wedzicha JA, Notari M, Zapata A, Segarra R, Seoane B, Jarreta D Tags: Am J Respir Crit Care Med Source Type: research

Therapeutic Targeting of High Mobility Group Box-1 in Pulmonary Arterial Hypertension.
PMID: 30939030 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 2, 2019 Category: Respiratory Medicine Authors: Goldenberg NM, Hu Y, Hu X, Volchuk A, Zhao YD, Kucherenko MM, Knosalla C, de Perrot M, Tracey KJ, Al-Abed Y, Steinberg BE, Kuebler WM Tags: Am J Respir Crit Care Med Source Type: research

Integrating Mechanical Ventilation and ECMO in Severe ARDS.
PMID: 30939044 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 2, 2019 Category: Respiratory Medicine Authors: Shekar K, Schmidt M Tags: Am J Respir Crit Care Med Source Type: research

Reply to: Integrating Mechanical Ventilation and ECMO in Severe ARDS.
PMID: 30939046 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 2, 2019 Category: Respiratory Medicine Authors: Araos J, Bruhn A Tags: Am J Respir Crit Care Med Source Type: research

A Golden Conundrum.
PMID: 30939047 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 2, 2019 Category: Respiratory Medicine Authors: Garner JL, Donovan J, Meireles I, Padley SPG, Cunningham D, Shah PL Tags: Am J Respir Crit Care Med Source Type: research

Unraveling the CFTR function-phenotype connection for precision treatment in CF.
PMID: 30939246 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 2, 2019 Category: Respiratory Medicine Authors: Zemanick ET, Polineni D Tags: Am J Respir Crit Care Med Source Type: research

Adenovirus Infection and Outbreaks: What You Need to Know.
PMID: 30932693 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 1, 2019 Category: Respiratory Medicine Authors: Dela Cruz CS, Pasnick S, Gross JE, Keller J, Carlos WG, Cao B, Jamil S Tags: Am J Respir Crit Care Med Source Type: research

Erratum: Loss of SMAD3 Promotes Vascular Remodeling in Pulmonary Arterial Hypertension via MRTF Disinhibition.
Authors: PMID: 30932694 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 1, 2019 Category: Respiratory Medicine Tags: Am J Respir Crit Care Med Source Type: research

Dietary Fat Intake, Particulate Matter Exposure and Asthma Severity.
PMID: 30922061 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 29, 2019 Category: Respiratory Medicine Authors: Rosa MJ, Perzanowski MS Tags: Am J Respir Crit Care Med Source Type: research

Omega-3 and Omega-6 Intake Modifies Asthma Severity and Response to Indoor Air Pollution in Children.
Abstract RATIONALE: Higher indoor particulate matter (PM) concentrations are linked with increased asthma morbidity. Dietary intake of fatty acids, also linked with asthma outcomes, may influence this relationship. OBJECTIVES: Determine (1) the relationship between omega-3 and omega-6 fatty acid intake and pediatric asthma morbidity, and (2) the association between fatty acid intake and strength of indoor, PM-related asthma symptoms, albuterol use, and systemic inflammation. METHODS: Analyses included 135 children with asthma enrolled in the AsthmaDIET Study. At baseline, 3, and 6 months, data included: ...
Source: American Journal of Respiratory and Critical Care Medicine - March 29, 2019 Category: Respiratory Medicine Authors: Brigham EP, Woo H, McCormack M, Rice J, Koehler K, Vulcain T, Wu T, Koch A, Sharma S, Kolahdooz F, Bose S, Hanson C, Romero K, Diette G, Hansel NN Tags: Am J Respir Crit Care Med Source Type: research

A Genetic Risk Score Associated with COPD Susceptibility and Lung Structure on Computed Tomography.
CONCLUSIONS: A GRS associated with COPD susceptibility was associated with CT lung structure. Lung structure may be an important mediator of heritability and determinant of personalized COPD risk. PMID: 30925230 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 29, 2019 Category: Respiratory Medicine Authors: Oelsner EC, Ortega VE, Smith BM, Nguyen JN, Manichaikul AW, Hoffman EA, Guo X, Taylor KD, Woodruff PG, Couper DJ, Hansel NN, Martinez FJ, Paine Iii R, Han MK, Cooper C, Dransfield MT, Criner G, Krishnan JA, Bowler R, Bleecker ER, Peters S, Rich SS, Meyers Tags: Am J Respir Crit Care Med Source Type: research

Sleep Apnea Heterogeneity, Phenotypes, and Cardiovascular Risk: Implications for Trial Design and Precision Sleep Medicine.
PMID: 30916985 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 27, 2019 Category: Respiratory Medicine Authors: Zinchuk A, Yaggi HK Tags: Am J Respir Crit Care Med Source Type: research

New Definition of Pulmonary Hypertension in Heart Failure with Preserved Ejection Fraction Patients.
PMID: 30917008 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 27, 2019 Category: Respiratory Medicine Authors: Nishihara T, Yamamoto E, Tokitsu T, Sueta D, Fujisue K, Usuku H, Takashio S, Sakamoto K, Kaikita K, Tsujita K Tags: Am J Respir Crit Care Med Source Type: research

CC16 - A Biomarker of Pollutant Exposure and Future Lung Disease?
PMID: 30917285 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 27, 2019 Category: Respiratory Medicine Authors: Laing IA Tags: Am J Respir Crit Care Med Source Type: research

Update in Cystic Fibrosis.
PMID: 30917288 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 27, 2019 Category: Respiratory Medicine Authors: Ramsey BW, Downey GP, Goss CH Tags: Am J Respir Crit Care Med Source Type: research

Trends in Asthma Mortality in the United States: 1999 to 2015.
PMID: 30917289 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 27, 2019 Category: Respiratory Medicine Authors: Pennington E, Yaqoob ZJ, Al-Kindi SG, Zein J Tags: Am J Respir Crit Care Med Source Type: research

Cryobiopsy for ILD: The Heat is On.
PMID: 30917297 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 27, 2019 Category: Respiratory Medicine Authors: Raghu G, Lederer DJ, Rabe KF Tags: Am J Respir Crit Care Med Source Type: research

Air Pollution Contributes to Asthma Deaths.
PMID: 30912954 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 26, 2019 Category: Respiratory Medicine Authors: Beamer PI Tags: Am J Respir Crit Care Med Source Type: research

Reply to: Fever in Sepsis: Still a Hot Topic.
PMID: 30908923 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 25, 2019 Category: Respiratory Medicine Authors: Bhavani SV, Verhoef PA, Churpek MM Tags: Am J Respir Crit Care Med Source Type: research

Understanding Patient-Ventilator Asynchrony Using Diaphragmatic Ultrasonography.
PMID: 30908924 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 25, 2019 Category: Respiratory Medicine Authors: Soilemezi E, Vasileiou M, Spyridonidou C, Tsagourias M, Matamis D Tags: Am J Respir Crit Care Med Source Type: research

Seeing the Forest for the (Arterial) Tree: Vascular Pruning & the COPD Pulmonary Vascular Phenotype.
Seeing the Forest for the (Arterial) Tree: Vascular Pruning & the COPD Pulmonary Vascular Phenotype. Am J Respir Crit Care Med. 2019 Mar 25;: Authors: Weatherald J, Montani D, Humbert M PMID: 30908925 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 25, 2019 Category: Respiratory Medicine Authors: Weatherald J, Montani D, Humbert M Tags: Am J Respir Crit Care Med Source Type: research

Fever in Sepsis: Still a Hot Topic.
PMID: 30908926 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 25, 2019 Category: Respiratory Medicine Authors: Leijte GP, Kox M, Pickkers P Tags: Am J Respir Crit Care Med Source Type: research

Functional Role of Inflammasome Activation in a Subset of Obese Non-Smoking Severe Asthmatics.
PMID: 30908928 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 25, 2019 Category: Respiratory Medicine Authors: Ruggeri P, Caramori G Tags: Am J Respir Crit Care Med Source Type: research