Is Interleukin 6 the Right Target in COVID-19 Severe Pneumonia?
PMID: 32955921 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 21, 2020 Category: Respiratory Medicine Authors: Blot M, Bourredjem A, Binquet C, Piroth L, LYMPHONIE Study Group Tags: Am J Respir Crit Care Med Source Type: research

Reply to: Blot et al. and Inoue et al.
PMID: 32955924 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 21, 2020 Category: Respiratory Medicine Authors: McElvaney OJ, McEvoy NL, McElvaney NG, Curley GF Tags: Am J Respir Crit Care Med Source Type: research

Role of IL-6 in Severe Inflammation.
PMID: 32955926 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 21, 2020 Category: Respiratory Medicine Authors: Inoue KI, Sagawa T, Takano H Tags: Am J Respir Crit Care Med Source Type: research

Control of Respiratory Drive by Non-invasive Ventilation as an Early Predictor of Success.
PMID: 32945689 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 18, 2020 Category: Respiratory Medicine Authors: Spinelli E, Marongiu I, Mauri T Tags: Am J Respir Crit Care Med Source Type: research

Continued Vigorous Inspiratory Effort as a Predictor of Non-invasive Ventilation Failure.
PMID: 32945690 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 18, 2020 Category: Respiratory Medicine Authors: Jha AK Tags: Am J Respir Crit Care Med Source Type: research

Reply to: Spinelli E, et al and Jha.
oni A PMID: 32945694 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 18, 2020 Category: Respiratory Medicine Authors: Tonelli R, Castaniere I, Fantini R, Tabbì L, Busani S, Pisani L, Nava S, Clini E, Marchioni A Tags: Am J Respir Crit Care Med Source Type: research

Sleep Apnea and COVID-19 Mortality and Hospitalization.
PMID: 32946275 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 18, 2020 Category: Respiratory Medicine Authors: Cade BE, Dashti HS, Hassan SM, Redline S, Karlson EW Tags: Am J Respir Crit Care Med Source Type: research

Time to Revisit the Hospital Readmissions Reduction Program for Patients Hospitalized for COPD Exacerbations.
PMID: 32946283 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 18, 2020 Category: Respiratory Medicine Authors: LaBedz S, Krishnan JA Tags: Am J Respir Crit Care Med Source Type: research

Reply to: COVID-19 Related Respiratory Failure and Lymphopenia Do Not Seem Associated with Pneumocystosis.
” PMID: 32941058 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 17, 2020 Category: Respiratory Medicine Authors: Menon AA, Berg DD, Gay EB, Fredenburgh LE, all the authors of “A Case of COVID-19 and Pneumocystis jirovecii Co-infection” Tags: Am J Respir Crit Care Med Source Type: research

COVID-19 Related Respiratory Failure and Lymphopenia Do Not Seem Associated with Pneumocystosis.
PMID: 32941062 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 17, 2020 Category: Respiratory Medicine Authors: Blaize M, Mayaux J, Luyt CE, Lampros A, Fekkar A Tags: Am J Respir Crit Care Med Source Type: research

Experimental Human Pneumococcal Colonisation in Older Adults is Feasible and Safe, Not Immunogenic.
CONCLUSIONS: In older adults, experimental pneumococcal colonisation is feasible and safe, but demonstrates different immunological outcomes compared with younger adults in previous studies. PMID: 32941735 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 17, 2020 Category: Respiratory Medicine Authors: Adler H, German EL, Mitsi E, Nikolaou E, Pojar S, Hales C, Robinson R, Connor V, Hill H, Hyder-Wright AD, Lazarova L, Lowe C, Smith EL, Wheeler I, Zaidi SR, Jochems SP, Loukov D, Reiné J, Solórzano-Gonzalez C, de Gorguette d'Argoeuves P, Jones T, Goldbl Tags: Am J Respir Crit Care Med Source Type: research

During the COVID-19 Pandemic, Lung Specialists of the World Implore You: Inhale Only Clean Air.
PMID: 32930633 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 15, 2020 Category: Respiratory Medicine Authors: Santhosh L, Alismail A, Breiburg A, Carlos G, Jamil S Tags: Am J Respir Crit Care Med Source Type: research

Erratum: Pharmacologic Management of Chronic Obstructive Pulmonary Disease. An Official American Thoracic Society Clinical Practice Guideline.
Authors: PMID: 32930634 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 15, 2020 Category: Respiratory Medicine Tags: Am J Respir Crit Care Med Source Type: research

Erratum: Lower Bacillus Calmette-Gu érin Protection against Mycobacterium tuberculosis Infection after Exposure to Beijing Strains.
Erratum: Lower Bacillus Calmette-Guérin Protection against Mycobacterium tuberculosis Infection after Exposure to Beijing Strains. Am J Respir Crit Care Med. 2020 Sep 15;202(6):909-910 Authors: PMID: 32930635 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 15, 2020 Category: Respiratory Medicine Tags: Am J Respir Crit Care Med Source Type: research

Network Analysis Subtleties in ICU Structures and Outcomes.
PMID: 32931298 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 15, 2020 Category: Respiratory Medicine Authors: Chen Y, Yan C, Patel MB Tags: Am J Respir Crit Care Med Source Type: research

What is "the Flu"?
What is "the Flu"? Am J Respir Crit Care Med. 2020 Sep 15;: Authors: Sockrider M PMID: 32931305 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 15, 2020 Category: Respiratory Medicine Authors: Sockrider M Tags: Am J Respir Crit Care Med Source Type: research

Reply to "Network Analysis Subtleties in ICU Structures and Outcomes".
Reply to "Network Analysis Subtleties in ICU Structures and Outcomes". Am J Respir Crit Care Med. 2020 Sep 15;: Authors: Costa DK, Liu H, Boltey EM, Yakusheva O PMID: 32931307 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 15, 2020 Category: Respiratory Medicine Authors: Costa DK, Liu H, Boltey EM, Yakusheva O Tags: Am J Respir Crit Care Med Source Type: research

Reply to: Anti-FXa Activity with Intermediate Dose Thromboprophylaxis in COVID-19.
Abstract Dutt T, Simcox D, Downey C, McLenaghan, D, King, C, Gautam, M, Lane, S, Burhan, H, Thromboprophylaxis in COVID-19: Anti-FXa - The Missing Factor? [published online ahead of print, 2020 Jun 8]. Am J Respir Crit Care Med. 2020;10.1164/rccm.202005-1654LE. doi:10.1164/rccm.202005-1654LE. PMID: 32931711 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 15, 2020 Category: Respiratory Medicine Authors: Dutt T, Simcox D, Downey C, McLenaghan D, King C, Gautam M, Lane S, Burhan H Tags: Am J Respir Crit Care Med Source Type: research

Anti-FXa Activity with Intermediate Dose Thromboprophylaxis in COVID-19.
PMID: 32931713 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 15, 2020 Category: Respiratory Medicine Authors: Rappaport SH, Clark JM, Delibert S, Maynard KM, Prasad P, Kaufman DC, Pietropaoli AP, Quill CM, Groth CM Tags: Am J Respir Crit Care Med Source Type: research

A New Piece to Help Solve the ILD Diagnostic Puzzle...
PMID: 32926641 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 14, 2020 Category: Respiratory Medicine Authors: Cosgrove GP, Lasky JA Tags: Am J Respir Crit Care Med Source Type: research

Pulmonary Vascular Pruning on Computed Tomography and Risk of Death in the Framingham Heart Study.
MA, Rice MB PMID: 32926788 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 14, 2020 Category: Respiratory Medicine Authors: Synn AJ, Li W, San José Estépar R, Washko GR, O'Connor GT, Tsao CW, Mittleman MA, Rice MB Tags: Am J Respir Crit Care Med Source Type: research

Novel Phenotypes in Respiratory Failure: Same As It Ever Was.
PMID: 32926789 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 14, 2020 Category: Respiratory Medicine Authors: Hardin CC Tags: Am J Respir Crit Care Med Source Type: research

CPAP Did Not Improve Nonalcoholic Fatty Liver Disease in Patients with Obstructive Sleep Apnea: A Randomized Clinical Trial.
Abstract RATIONALE: Obstructive sleep apnea (OSA) is associated with development of nonalcoholic fatty liver disease (NAFLD). The effects of continuous positive airway pressure (CPAP) on NAFLD in patients with concomitant OSA are unknown. OBJECTIVES: To investigate the effects of autoCPAP versus subtherapeutic CPAP treatment over 6 months on NAFLD activities. METHODS: Patients with NAFLD and OSA, as defined by respiratory event index (REI) ≥ 5/hr diagnosed by a validated level 3 Embletta device, were randomized into group A) autoCPAP (4-20cmH2O) or group B) subtherapeutic CPAP (pressure fixed at 4cmH2...
Source: American Journal of Respiratory and Critical Care Medicine - September 14, 2020 Category: Respiratory Medicine Authors: Ng SS, Wong VW, Wong GL, Chu WC, Chan TO, To KW, Ko FW, Chan KP, Hui DS Tags: Am J Respir Crit Care Med Source Type: research

Branching Out in Chronic Cough; Evidence for Increased Airway Nerve Density.
PMID: 32926806 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 14, 2020 Category: Respiratory Medicine Authors: Smith JA, West PW Tags: Am J Respir Crit Care Med Source Type: research

Immunomodulators in COVID-19 - Two Sides to Every Coin.
PMID: 32926809 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 14, 2020 Category: Respiratory Medicine Authors: Snow TA, Singer M, Arulkumaran N Tags: Am J Respir Crit Care Med Source Type: research

Sleep Disordered Breathing and Insomnia as Cardiometabolic Risk Factors Among US Hispanics/Latinos.
PMID: 32916057 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 11, 2020 Category: Respiratory Medicine Authors: Ghani SB, Begay TK, Grandner MA Tags: Am J Respir Crit Care Med Source Type: research

Reproducible Single-cell Genomic Research in Pulmonary and Critical Care Medicine.
PMID: 32916059 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 11, 2020 Category: Respiratory Medicine Authors: Eickelberg O, Misharin AV, Sime PJ Tags: Am J Respir Crit Care Med Source Type: research

Rethinking Alveolar Ventilation and CO2 Removal.
PMID: 32916061 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 11, 2020 Category: Respiratory Medicine Authors: Cove ME, Pinsky MR Tags: Am J Respir Crit Care Med Source Type: research

In Pursuit of Microbiome-based Therapies for Acute Respiratory Failure.
PMID: 32910676 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 10, 2020 Category: Respiratory Medicine Authors: Ali F, Sweeney DA Tags: Am J Respir Crit Care Med Source Type: research

In COPD Progression, Is It Airway Narrowing or Airway Loss?
PMID: 32910677 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 10, 2020 Category: Respiratory Medicine Authors: Rizi RR, Hamedani H, Cereda M Tags: Am J Respir Crit Care Med Source Type: research

MSC-derived Exosomes :Are They Another Therapeutic Method for ECMO-supported ARDS?
MSC-derived Exosomes:Are They Another Therapeutic Method for ECMO-supported ARDS? Am J Respir Crit Care Med. 2020 Sep 09;: Authors: Zhang L, Hei F PMID: 32903027 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 9, 2020 Category: Respiratory Medicine Authors: Zhang L, Hei F Tags: Am J Respir Crit Care Med Source Type: research

Reply to: MSC-derived Exosomes: Are They Another Therapeutic Method for ECMO-supported ARDS?
’ PMID: 32903045 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 9, 2020 Category: Respiratory Medicine Authors: Millar JE, Suen JY, McAuley DF, Fraser JF, all authors of ‘Combined Mesenchymal Stromal Cell Therapy and Extracorporeal Membrane Oxygenation in Acute Respiratory Distress Syndrome: A Controlled Experimental Study in Sheep.’ Tags: Am J Respir Crit Care Med Source Type: research

Congenital Lobar Emphysema in an Elderly Patient.
PMID: 32897729 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 8, 2020 Category: Respiratory Medicine Authors: Shen C, Che G Tags: Am J Respir Crit Care Med Source Type: research

Complement Inhibition with the C5 Blocker LFG316 in Severe COVID-19.
PMID: 32897730 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 8, 2020 Category: Respiratory Medicine Authors: Zelek WM, Cole J, Ponsford MJ, Harrison RA, Schroeder BE, Webb N, Jolles S, Fegan C, Morgan M, Wise MP, Morgan BP Tags: Am J Respir Crit Care Med Source Type: research

Increased Odds of Death for Patients with Interstitial Lung Disease and COVID-19: A Case-Control Study.
PMID: 32897754 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 8, 2020 Category: Respiratory Medicine Authors: Esposito AJ, Menon AA, Ghosh AJ, Putman RK, Fredenburgh LE, El-Chemaly SY, Goldberg HJ, Baron RM, Hunninghake GM, Doyle TJ Tags: Am J Respir Crit Care Med Source Type: research

Cardiopulmonary Resuscitation-Associated Lung Edema (CRALE) - A Translational Study.
Abstract RATIONALE: Cardiopulmonary Resuscitation is the cornerstone of cardiac arrest (CA) treatment. However, lung injuries associated with it have been reported. OBJECTIVES: To assess 1) the presence and characteristics of lung abnormalities induced by Cardiopulmonary Resuscitation and 2) the role of mechanical and manual chest compression (CC) in its development. METHODS: This translational study included : 1) a porcine model of CA and Cardiopulmonary Resuscitation (n=12), 2) a multicenter cohort of out-of-hospital CA patients undergoing mechanical or manual CC (n=52). Lung Computed Tomography perfor...
Source: American Journal of Respiratory and Critical Care Medicine - September 8, 2020 Category: Respiratory Medicine Authors: Magliocca A, Rezoagli E, Zani D, Manfredi M, De Giorgio D, Olivari D, Fumagalli F, Langer T, Avalli L, Grasselli G, Latini R, Pesenti A, Bellani G, Ristagno G Tags: Am J Respir Crit Care Med Source Type: research

Development and Validation of SDBeasy Score as a Predictor of Behavioral Outcomes in Childhood.
Abstract RATIONALE: There are limited tools to identify which children are at greatest risk for developing Sleep Disordered Breathing (SDB)-associated behavioral morbidity. OBJECTIVES: To examine associations between age of onset and duration of parent-reported symptoms of SDB and behavioral problems at age five years. METHODS: Data collection and analyses were completed among CHILD cohort Edmonton and Toronto-site participants. We generated an SDBeasy score based on the age of onset and duration of SDB symptoms as reported by parents completing the pediatric sleep questionnaire (PSQ). Using CHILD Edmont...
Source: American Journal of Respiratory and Critical Care Medicine - September 8, 2020 Category: Respiratory Medicine Authors: van Eeden C, Tamana SK, Narang I, Hammam N, Chikuma J, Lefebvre DL, Azad MB, Moraes TJ, Subbarao P, Becker AB, Turvey SE, Sears MR, Rasmussen C, Pei J, Mandhane PJ Tags: Am J Respir Crit Care Med Source Type: research

The Respiratory Drive: An Overlooked Tile of COVID-19 Pathophysiology.
PMID: 32881583 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 3, 2020 Category: Respiratory Medicine Authors: Gattinoni L, Marini JJ, Camporota L Tags: Am J Respir Crit Care Med Source Type: research

High Pleural Pressure Prevents Alveolar Overdistension and Hemodynamic Collapse in ARDS with Class III Obesity.
Conclusions: High airway pressure is required to recruit lung atelectasis in patients with ARDS and class III obesity but causes minimal overdistension. Additionally, patients with ARDS and class III obesity tolerate hemodynamically LRM with high airway pressure. PMID: 32876469 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 2, 2020 Category: Respiratory Medicine Authors: De Santis Santiago R, Teggia Droghi M, Fumagalli J, Marrazzo F, Florio G, Grassi LG, Gomes S, Morais CCA, Ramos OPS, Bottiroli M, Pinciroli R, Imber DA, Bagchi A, Shelton K, Sonny A, Bittner EA, Amato MBP, Kacmarek RM, Berra L, Lung Rescue Team Investigat Tags: Am J Respir Crit Care Med Source Type: research

High Flow Aerosol Dispersing- Versus Aerosol Generating Procedures.
PMID: 32877201 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 2, 2020 Category: Respiratory Medicine Authors: Li J, Ehrmann S Tags: Am J Respir Crit Care Med Source Type: research

In Vivo Generation of Lung and Thyroid Tissues from Embryonic Stem Cells using Blastocyst Complementation.
CONCLUSIONS: Lung and thyroid tissues were generated in vivo from ESCs by blastocyst complementation. Nkx2-1-/- chimeras can be used as "bioreactors" for in vivo differentiation and functional studies of ESC-derived progenitor cells. PMID: 32877203 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 2, 2020 Category: Respiratory Medicine Authors: Wen B, Li E, Ustiyan V, Wang G, Guo M, Na CL, Kalin GT, Galvan V, Xu Y, Weaver TE, Kalin TV, Whitsett JA, Kalinichenko VV Tags: Am J Respir Crit Care Med Source Type: research

Use of Hydrocortisone Based on Plasma Biomarkers in Patients with Septic Shock: Another One Bites the Dust?
ani W PMID: 32870033 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 1, 2020 Category: Respiratory Medicine Authors: Møller MH, Shankar-Hari M, Alhazzani W Tags: Am J Respir Crit Care Med Source Type: research

Erratum: Cardiopulmonary Exercise Testing Provides Additional Prognostic Information in Cystic Fibrosis.
Authors: PMID: 32870034 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 1, 2020 Category: Respiratory Medicine Tags: Am J Respir Crit Care Med Source Type: research

Face Coverings in a Pandemic.
PMID: 32870035 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 1, 2020 Category: Respiratory Medicine Authors: McGraw MD, Achanta S, Castner J, Gold DR, Hines SE, Redlich CA, Sockrider MM Tags: Am J Respir Crit Care Med Source Type: research

COVID-19: How Do We Stay Safe?
PMID: 32870036 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 1, 2020 Category: Respiratory Medicine Authors: Carlos WG, Cruz CSD, Cao B, Gross JE, Pasnick S, Jamil S Tags: Am J Respir Crit Care Med Source Type: research

In Search of "hepatic factor:" Lack of Evidence for ALK1 Ligands BMP9 and BMP10.
In Search of "hepatic factor:" Lack of Evidence for ALK1 Ligands BMP9 and BMP10. Am J Respir Crit Care Med. 2020 Sep 01;: Authors: Capasso TL, Trucco SM, Hindes M, Schwartze T, Bloch JL, Kreutzer J, Cook SC, Hinck CS, Treggiari D, Feingold B, Hinck AP, Roman BL PMID: 32871084 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 1, 2020 Category: Respiratory Medicine Authors: Capasso TL, Trucco SM, Hindes M, Schwartze T, Bloch JL, Kreutzer J, Cook SC, Hinck CS, Treggiari D, Feingold B, Hinck AP, Roman BL Tags: Am J Respir Crit Care Med Source Type: research

Live-attenuated Vaccines Prevent Respiratory Syncytial Virus-associated Illness in Young Children.
CONCLUSIONS: Rapid development of a live-attenuated RSV vaccine could contribute substantially to reducing the global burden of RSV disease. PMID: 32871092 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 1, 2020 Category: Respiratory Medicine Authors: Karron RA, Atwell JE, McFarland EJ, Cunningham CK, Muresan P, Perlowski C, Libous J, Spector SA, Yogev R, Aziz M, Woods S, Wanionek K, Collins PL, Buchholz UJ Tags: Am J Respir Crit Care Med Source Type: research

Readmissions Reduction Program, Mortality and Readmissions for Chronic Obstructive Pulmonary Disease.
CONCLUSIONS: We found a reduction in 30-day all-cause readmission rate during the implementation period compared to the pre-announcement phase. HRRP implementation was also associated with a significant increase in 30-day mortality after discharge from COPD hospitalization. Additional research is necessary to confirm our findings and understand the factors contributing to increased mortality in patients with COPD in the HRRP implementation period. PMID: 32871097 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 1, 2020 Category: Respiratory Medicine Authors: Puebla Neira DA, Hsu ES, Kuo YF, Ottenbacher KJ, Sharma G Tags: Am J Respir Crit Care Med Source Type: research

Severe Acute Kidney Injury in COVID-19 Patients with Acute Respiratory Distress Syndrome.
Gaudry S PMID: 32866028 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - August 31, 2020 Category: Respiratory Medicine Authors: Chaïbi K, Dao M, Pham T, Gumucio-Sanguino VD, Di Paolo FA, Pavot A, Cohen Y, Dreyfuss D, Pérez-Fernandez X, Gaudry S Tags: Am J Respir Crit Care Med Source Type: research

Uncontrolled Innate and Impaired Adaptive Immune Responses in Patients with COVID-19 ARDS.
Abstract RATIONALE: Uncontrolled inflammatory innate response and impaired adaptive immune response are associated with clinical severity in patients with Coronavirus disease 2019 (COVID-19). OBJECTIVES: To compare the immunopathology of COVID-19 acute respiratory distress syndrome (ARDS) to that of non-COVID-19 ARDS, and to identify biomarkers associated with mortality in patients with COVID-19 ARDS. METHODS: Prospective observational monocenter study. Immunocompetent patients diagnosed with RT-PCR-confirmed SARS-CoV-2 infection and ARDS admitted between March 8 and March 30, 2020 were included and comp...
Source: American Journal of Respiratory and Critical Care Medicine - August 31, 2020 Category: Respiratory Medicine Authors: Hue S, Beldi-Ferchiou A, Bendib I, Surenaud M, Fourati S, Frapard T, Rivoal S, Razazi K, Carteaux G, Delfau-Larue MH, Mekontso Dessap A, Audureau E, de Prost N Tags: Am J Respir Crit Care Med Source Type: research