Of Mucus and Microbes: The Sticky Issue of Mucin-Microbiome Interactions in COPD
Am J Respir Crit Care Med. 2024 Mar 26. doi: 10.1164/rccm.202403-0506ED. Online ahead of print.NO ABSTRACTPMID:38530107 | DOI:10.1164/rccm.202403-0506ED (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 26, 2024 Category: Respiratory Medicine Authors: Yvonne J Huang Source Type: research

Vive la Resistome: Are We Ready for a Metagenomics Revolution in Bronchiectasis?
Am J Respir Crit Care Med. 2024 Mar 26. doi: 10.1164/rccm.202402-0352ED. Online ahead of print.NO ABSTRACTPMID:38530113 | DOI:10.1164/rccm.202402-0352ED (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 26, 2024 Category: Respiratory Medicine Authors: Shivani Singh Leopoldo N Segal Source Type: research

Ventilator-associated Brain Injury - VABI: A New Priority for Research in Mechanical Ventilation
Am J Respir Crit Care Med. 2024 Mar 25. doi: 10.1164/rccm.202401-0069VP. Online ahead of print.NO ABSTRACTPMID:38526447 | DOI:10.1164/rccm.202401-0069VP (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 25, 2024 Category: Respiratory Medicine Authors: Thiago Bassi Shaurya Taran Timothy D Girard Chiara Robba Ewan C Goligher Source Type: research

Physiologic Effects of ECMO in Patients with Severe Acute Respiratory Distress Syndrome
CONCLUSIONS: In severe ARDS patients, increased ECMO blood flow rate resulting in higher SvO2 decreases pulmonary artery pressure, cardiac output, and right heart workload.PMID:38526489 | DOI:10.1164/rccm.202309-1688OC (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 25, 2024 Category: Respiratory Medicine Authors: Elena Spinelli Marco Giani Douglas Slobod Bertrand Pavlovsky Michela di Pierro Stefania Crotti Alfredo Lissoni Giuseppe Foti Giacomo Grasselli Tommaso Mauri Source Type: research

The Effect of Chronic Altitude Exposure on COPD Outcomes in the SPIROMICS Cohort
CONCLUSIONS: Chronic altitude exposure is associated with reduced functional exercise capacity in individuals with COPD, but this did not translate into differences in symptoms or health status. Additionally, chronic high-altitude exposure did not affect progression of disease as defined by longitudinal changes in spirometry.PMID:38507607 | DOI:10.1164/rccm.202310-1965OC (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 20, 2024 Category: Respiratory Medicine Authors: Rajat Suri Daniela Markovic Han Woo Mehrdad Arjomandi R Graham Barr Russell P Bowler Gerard Criner Jeffrey L Curtis Mark T Dransfield M Bradley Drummond Spyridon Fortis MeiLan K Han Eric A Hoffman Robert J Kaner Joel D Kaufman Jerry A Krishnan Fernando J Source Type: research

CRISPR/Cas9 Genome Editing Allows Generation of the Mouse Lung in a Rat
CONCLUSIONS: A combination of CRISPR/Cas9 genome editing and blastocyst complementation was used to produce mouse lungs in rats, making an important step toward future generations of human lungs using large animals as "bioreactors".PMID:38507610 | DOI:10.1164/rccm.202306-0964OC (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 20, 2024 Category: Respiratory Medicine Authors: Bingqiang Wen Enhong Li Guolun Wang Timothy R Kalin Dongfeng Gao Peixin Lu Tanya V Kalin Vladimir V Kalinichenko Source Type: research

Pitfalls of ARDS Diagnosis Based on Interventions
Am J Respir Crit Care Med. 2024 Mar 20. doi: 10.1164/rccm.202308-1368LE. Online ahead of print.NO ABSTRACTPMID:38507733 | DOI:10.1164/rccm.202308-1368LE (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 20, 2024 Category: Respiratory Medicine Authors: Rong Liufu Li Weng Chun-Yao Wang Bin Du Source Type: research

"PEEP-Adjusted P/F Ratio" in ARDS - A Call for Further Enhancement of Global Definition
Am J Respir Crit Care Med. 2024 Mar 20. doi: 10.1164/rccm.202308-1428LE. Online ahead of print.NO ABSTRACTPMID:38507734 | DOI:10.1164/rccm.202308-1428LE (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 20, 2024 Category: Respiratory Medicine Authors: Sunitha Palanidurai Yiong Huak Chan Amartya Mukhopadhyay Source Type: research

Reply to Du, < em > et al. < /em > and Palanidurai, < em > et al < /em >
Am J Respir Crit Care Med. 2024 Mar 20. doi: 10.1164/rccm.202402-0284LE. Online ahead of print.NO ABSTRACTPMID:38507735 | DOI:10.1164/rccm.202402-0284LE (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 20, 2024 Category: Respiratory Medicine Authors: Michael A Matthay Lorraine B Ware Elisabeth D Riviello Katherine D Wick Taylor Thompson Thomas R Martin Source Type: research

The Effect of Chronic Altitude Exposure on COPD Outcomes in the SPIROMICS Cohort
CONCLUSIONS: Chronic altitude exposure is associated with reduced functional exercise capacity in individuals with COPD, but this did not translate into differences in symptoms or health status. Additionally, chronic high-altitude exposure did not affect progression of disease as defined by longitudinal changes in spirometry.PMID:38507607 | DOI:10.1164/rccm.202310-1965OC (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 20, 2024 Category: Respiratory Medicine Authors: Rajat Suri Daniela Markovic Han Woo Mehrdad Arjomandi R Graham Barr Russell P Bowler Gerard Criner Jeffrey L Curtis Mark T Dransfield M Bradley Drummond Spyridon Fortis MeiLan K Han Eric A Hoffman Robert J Kaner Joel D Kaufman Jerry A Krishnan Fernando J Source Type: research

CRISPR/Cas9 Genome Editing Allows Generation of the Mouse Lung in a Rat
CONCLUSIONS: A combination of CRISPR/Cas9 genome editing and blastocyst complementation was used to produce mouse lungs in rats, making an important step toward future generations of human lungs using large animals as "bioreactors".PMID:38507610 | DOI:10.1164/rccm.202306-0964OC (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 20, 2024 Category: Respiratory Medicine Authors: Bingqiang Wen Enhong Li Guolun Wang Timothy R Kalin Dongfeng Gao Peixin Lu Tanya V Kalin Vladimir V Kalinichenko Source Type: research

Pitfalls of ARDS Diagnosis Based on Interventions
Am J Respir Crit Care Med. 2024 Mar 20. doi: 10.1164/rccm.202308-1368LE. Online ahead of print.NO ABSTRACTPMID:38507733 | DOI:10.1164/rccm.202308-1368LE (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 20, 2024 Category: Respiratory Medicine Authors: Rong Liufu Li Weng Chun-Yao Wang Bin Du Source Type: research

"PEEP-Adjusted P/F Ratio" in ARDS - A Call for Further Enhancement of Global Definition
Am J Respir Crit Care Med. 2024 Mar 20. doi: 10.1164/rccm.202308-1428LE. Online ahead of print.NO ABSTRACTPMID:38507734 | DOI:10.1164/rccm.202308-1428LE (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 20, 2024 Category: Respiratory Medicine Authors: Sunitha Palanidurai Yiong Huak Chan Amartya Mukhopadhyay Source Type: research

Reply to Du, < em > et al. < /em > and Palanidurai, < em > et al < /em >
Am J Respir Crit Care Med. 2024 Mar 20. doi: 10.1164/rccm.202402-0284LE. Online ahead of print.NO ABSTRACTPMID:38507735 | DOI:10.1164/rccm.202402-0284LE (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 20, 2024 Category: Respiratory Medicine Authors: Michael A Matthay Lorraine B Ware Elisabeth D Riviello Katherine D Wick Taylor Thompson Thomas R Martin Source Type: research

The Effect of Chronic Altitude Exposure on COPD Outcomes in the SPIROMICS Cohort
CONCLUSIONS: Chronic altitude exposure is associated with reduced functional exercise capacity in individuals with COPD, but this did not translate into differences in symptoms or health status. Additionally, chronic high-altitude exposure did not affect progression of disease as defined by longitudinal changes in spirometry.PMID:38507607 | DOI:10.1164/rccm.202310-1965OC (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 20, 2024 Category: Respiratory Medicine Authors: Rajat Suri Daniela Markovic Han Woo Mehrdad Arjomandi R Graham Barr Russell P Bowler Gerard Criner Jeffrey L Curtis Mark T Dransfield M Bradley Drummond Spyridon Fortis MeiLan K Han Eric A Hoffman Robert J Kaner Joel D Kaufman Jerry A Krishnan Fernando J Source Type: research