Peculiar Prepuce: A Rare Case of Penile Lymphangioma
A 39-year-old male with no other dermatologic or urologic history presented to urology with penile lesions for 4 years. The lesions are intermittently itchy, not painful, and do not interfere with erection or sexual activity. They did not respond to a six-week course of imiquimod prescribed by his PCP or cryotherapy of selected lesions by dermatology. He is bothered by their appearance. His phallus is uncircumcised with easily retractable foreskin. Punch biopsy histology is shown in Figure 1: (Source: Urology)
Source: Urology - May 6, 2022 Category: Urology & Nephrology Authors: James M. Jones, Martin S. Gross, Michael E. Rezaee Source Type: research
Breakthrough Penile Mucormycosis in a Patient With Acute Myelogenous Leukemia on Posaconazole Prophylaxis
In patients with acute myelogenous leukemia, posaconazole prophylaxis has been shown to prevent deep invasive fungal infections, including mucormycosis. In the present case, posaconazole prophylaxis was initiated in a 58-year-old man undergoing induction chemotherapy for acute myelogenous leukemia. Three weeks after initiating chemotherapy, he developed a tender violaceous macule on the shaft of his penis. The initial differential included fixed drug eruption versus pyoderma gangrenosum. However, punch biopsy ultimately showed mucormycosis, and cultures grew Rhizopus species, despite therapeutic posaconazole trough. He was...
Source: Infectious Diseases in Clinical Practice - May 1, 2022 Category: Infectious Diseases Tags: Case Report Source Type: research
Primary seminoma of prostate in a patient with Klinefelter syndrome: A case report
Rationale:
Klinefelter syndrome (KS) is a sex differentiation syndrome that occurs in men and is characterized by the 47XXY genotype. An association between KS and cancer has also been reported. The occurrence of seminoma of the prostate in KS has not been reported in the literature to date. Primary seminoma should be included in the differential diagnosis of prostate neoplasms in patients with KS.
Patient concerns:
A 39-year-old man presenting with urinary retention was admitted to our hospital. Physical examination revealed sparse pubic hairs, atrophic testes, and an underdeveloped penis. Hormonal examination ...
Source: Medicine - April 29, 2022 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Radioisotope-Guided Sentinel Lymph Node Biopsy in Penile Cancer: A Long-Term Follow-Up Study
Lymph node (LN) management is critical for survival in patients with penile cancer. However, radical inguinal lymphadenectomy carries a high risk of postoperative complications such as lymphedema, lymphocele, wound infection, and skin necrosis. The European Association of Urology guidelines therefore recommend invasive LN staging by modified inguinal lymphadenectomy or dynamic sentinel node biopsy (DSNB) in clinically node-negative patients (cN0) with intermediate- and high-risk tumors (≥ T1G2). However, the timing of DSNB (simultaneous vs. subsequent to partial or total penile resection) is controversial and the low inc...
Source: Frontiers in Oncology - April 14, 2022 Category: Cancer & Oncology Source Type: research
Diffusion-Weighted MRI in the Genitourinary System
In conclusion, DWI constitutes a major advancement in genitourinary imaging with a central role in decision algorithms in the female pelvis and prostate cancer, now allowing promising applications in renal imaging or in the bladder and testicular mpMRI.PMID:35407528 | DOI:10.3390/jcm11071921 (Source: Clinical Prostate Cancer)
Source: Clinical Prostate Cancer - April 12, 2022 Category: Cancer & Oncology Authors: Thomas De Perrot Christine Sadjo Zoua Carl G Glessgen Diomidis Botsikas Lena Berchtold Rares Salomir Sophie De Seigneux Harriet C Thoeny Jean-Paul Vall ée Source Type: research
Diffusion-Weighted MRI in the Genitourinary System
In conclusion, DWI constitutes a major advancement in genitourinary imaging with a central role in decision algorithms in the female pelvis and prostate cancer, now allowing promising applications in renal imaging or in the bladder and testicular mpMRI.PMID:35407528 | PMC:PMC9000195 | DOI:10.3390/jcm11071921 (Source: Clinical Prostate Cancer)
Source: Clinical Prostate Cancer - April 12, 2022 Category: Cancer & Oncology Authors: Thomas De Perrot Christine Sadjo Zoua Carl G Glessgen Diomidis Botsikas Lena Berchtold Rares Salomir Sophie De Seigneux Harriet C Thoeny Jean-Paul Vall ée Source Type: research
Lymphovascular and perineural invasion are risk factors for inguinal lymph node metastases in men with T1G2 penile cancer
ConclusionApproximately, one out of ten men with T1G2 overall and one out of four men with either LVI + or PNI + still have ILN metastases despite being clinically node negative. Therefore, invasive ILN staging should strongly be recommended in T1G2 with LVI + or PNI + but importantly, must be discussed in patients with T1G2 with LVI- or PNI-. (Source: Journal of Cancer Research and Clinical Oncology)
Source: Journal of Cancer Research and Clinical Oncology - April 12, 2022 Category: Cancer & Oncology Source Type: research
The role of occlusion and micro-incontinence in the pathogenesis of penile lichen sclerosus: an observational study of pro-inflammatory cytokines ’ gene expression
ConclusionOcclusion and irritating urine effect are associated with the clinical progression of penile LS with increased mRNA expression of IL-1A, INF- γ, and IL-6 pro-inflammatory cytokines in the foreskin. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - March 16, 2022 Category: Urology & Nephrology Source Type: research
Dynamic Sentinel Lymph Node Biopsy for Penile Cancer: Accuracy is in the Technique
: To demonstrate an operative standard for dynamic sentinel lymph node biopsy (DSLNB). Long-term survival in men with penile squamous cell carcinoma (SCC) depends on accurately staging lymph node metastases. European Association of Urology (EAU) and National Comprehensive Cancer Network (NCCN) guidelines recognize DSLNB as a standard for staging men with intermediate to high-risk tumors and clinically absent inguinal lymphadenopathy. DSLNB accuracy has been linked with pre-operative planning and surgical technique, yet no peer-reviewed video exists to establish an operative standard. (Source: Urology)
Source: Urology - March 10, 2022 Category: Urology & Nephrology Authors: Jonathan S O'Brien, Jiasian Teh, Kenneth Chen, Brian Kelly, Justin Chee, Nathan Lawrentschuk Source Type: research
Inverted urethral flap reconstruction after partial penectomy: Long-term oncological and functional outcomes
CONCLUSIONS: To the best of our knowledge, we report the largest cohort in the literature of PP with IUF reconstruction. These results are important since early-stage PC is the most common stage at diagnosis. In carefully selected patients' preservation of a longer urethral stump to allow for the inverted flap is safe and does not compromise oncological outcomes while preserving HRQoL.PMID:35260297 | DOI:10.1016/j.urolonc.2022.02.006 (Source: Urologic Oncology)
Source: Urologic Oncology - March 9, 2022 Category: Urology & Nephrology Authors: Juli án Chavarriaga Luis Becerra Diego Camacho Fabi án Godoy Jorge Forero Marino Cabrera Byron L ópez-de-Mesa Angie Ramirez Daniel Suso-Palau Rodolfo Varela Source Type: research
Inverted urethral flap reconstruction after partial penectomy: Long-term oncological and functional outcomes
CONCLUSIONS: To the best of our knowledge, we report the largest cohort in the literature of PP with IUF reconstruction. These results are important since early-stage PC is the most common stage at diagnosis. In carefully selected patients' preservation of a longer urethral stump to allow for the inverted flap is safe and does not compromise oncological outcomes while preserving HRQoL.PMID:35260297 | DOI:10.1016/j.urolonc.2022.02.006 (Source: Urologic Oncology)
Source: Urologic Oncology - March 9, 2022 Category: Urology & Nephrology Authors: Juli án Chavarriaga Luis Becerra Diego Camacho Fabi án Godoy Jorge Forero Marino Cabrera Byron L ópez-de-Mesa Angie Ramirez Daniel Suso-Palau Rodolfo Varela Source Type: research
Inverted urethral flap reconstruction after partial penectomy: Long-term oncological and functional outcomes
CONCLUSIONS: To the best of our knowledge, we report the largest cohort in the literature of PP with IUF reconstruction. These results are important since early-stage PC is the most common stage at diagnosis. In carefully selected patients' preservation of a longer urethral stump to allow for the inverted flap is safe and does not compromise oncological outcomes while preserving HRQoL.PMID:35260297 | DOI:10.1016/j.urolonc.2022.02.006 (Source: Urologic Oncology)
Source: Urologic Oncology - March 9, 2022 Category: Urology & Nephrology Authors: Juli án Chavarriaga Luis Becerra Diego Camacho Fabi án Godoy Jorge Forero Marino Cabrera Byron L ópez-de-Mesa Angie Ramirez Daniel Suso-Palau Rodolfo Varela Source Type: research
Inverted urethral flap reconstruction after partial penectomy: Long-term oncological and functional outcomes
CONCLUSIONS: To the best of our knowledge, we report the largest cohort in the literature of PP with IUF reconstruction. These results are important since early-stage PC is the most common stage at diagnosis. In carefully selected patients' preservation of a longer urethral stump to allow for the inverted flap is safe and does not compromise oncological outcomes while preserving HRQoL.PMID:35260297 | DOI:10.1016/j.urolonc.2022.02.006 (Source: Urologic Oncology)
Source: Urologic Oncology - March 9, 2022 Category: Urology & Nephrology Authors: Juli án Chavarriaga Luis Becerra Diego Camacho Fabi án Godoy Jorge Forero Marino Cabrera Byron L ópez-de-Mesa Angie Ramirez Daniel Suso-Palau Rodolfo Varela Source Type: research
The role of occlusion and micro-incontinence in the pathogenesis of penile lichen sclerosus: an observational study of pro-inflammatory cytokines' gene expression
CONCLUSION: Occlusion and irritating urine effect are associated with the clinical progression of penile LS with increased mRNA expression of IL-1A, INF-γ, and IL-6 pro-inflammatory cytokines in the foreskin.PMID:35103930 | DOI:10.1007/s11255-022-03130-7 (Source: Cancer Control)
Source: Cancer Control - February 1, 2022 Category: Cancer & Oncology Authors: M Czajkowski P Wierzbicki A Kotulak-Chrz ąszcz K Czajkowska M Bolcewicz J K łącz K Kreft A Lewandowska B Nedoszytko M Soko łowska-Wojdyło Z Kmie ć L Kalinowski R J Nowicki M Matuszewski Source Type: research
