Acute urinary retention due to corpus cavernosum penile metastasis from lung adenocarcinoma after targeted therapy: a case report and review of the literature
ConclusionThe penis may be a site of metastasis from primary lung cancer, especially for old patient. Metastasis to the penis usually indicates that the primary lung cancer is at an advanced stage and the prognosis is very poor. More research is necessary to understand the underlying mechanism of adenocarcinoma of lung metastasis. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - March 1, 2024 Category: Cancer & Oncology Source Type: research

Primary signet ring cell adenocarcinoma arising in exstrophy of the urinary bladder (epispadias-exstrophy complex)
Indian J Pathol Microbiol. 2023 Nov 9. doi: 10.4103/ijpm.ijpm_1025_22. Online ahead of print.ABSTRACTBladder exstrophy is a rare congenital anomaly in which the urinary bladder develops outside the body. It may be part of the bladder epispadias-exstrophy-cloacal complex, which is a serious embryological defect where a spectrum of abnormalities involving the urinary tract, genital tract, musculoskeletal system, and intestinal tract is seen. Primary signet ring cell adenocarcinoma (PSRCA) arising in exstrophy of the urinary bladder is extremely rare with only a few cases reported in the literature. A 32-year-old man with con...
Source: Indian Journal of Pathology and Microbiology - February 23, 2024 Category: Pathology Authors: Gwendolyn Fernandes Gloria Khumanthem Nupur Harinkhede Amey Rojekar Source Type: research

Primary signet ring cell adenocarcinoma arising in exstrophy of the urinary bladder (epispadias-exstrophy complex)
Indian J Pathol Microbiol. 2023 Nov 9. doi: 10.4103/ijpm.ijpm_1025_22. Online ahead of print.ABSTRACTBladder exstrophy is a rare congenital anomaly in which the urinary bladder develops outside the body. It may be part of the bladder epispadias-exstrophy-cloacal complex, which is a serious embryological defect where a spectrum of abnormalities involving the urinary tract, genital tract, musculoskeletal system, and intestinal tract is seen. Primary signet ring cell adenocarcinoma (PSRCA) arising in exstrophy of the urinary bladder is extremely rare with only a few cases reported in the literature. A 32-year-old man with con...
Source: Indian Journal of Pathology and Microbiology - February 23, 2024 Category: Pathology Authors: Gwendolyn Fernandes Gloria Khumanthem Nupur Harinkhede Amey Rojekar Source Type: research

Primary signet ring cell adenocarcinoma arising in exstrophy of the urinary bladder (epispadias-exstrophy complex)
Indian J Pathol Microbiol. 2023 Nov 9. doi: 10.4103/ijpm.ijpm_1025_22. Online ahead of print.ABSTRACTBladder exstrophy is a rare congenital anomaly in which the urinary bladder develops outside the body. It may be part of the bladder epispadias-exstrophy-cloacal complex, which is a serious embryological defect where a spectrum of abnormalities involving the urinary tract, genital tract, musculoskeletal system, and intestinal tract is seen. Primary signet ring cell adenocarcinoma (PSRCA) arising in exstrophy of the urinary bladder is extremely rare with only a few cases reported in the literature. A 32-year-old man with con...
Source: Indian Journal of Pathology and Microbiology - February 23, 2024 Category: Pathology Authors: Gwendolyn Fernandes Gloria Khumanthem Nupur Harinkhede Amey Rojekar Source Type: research

Primary signet ring cell adenocarcinoma arising in exstrophy of the urinary bladder (epispadias-exstrophy complex)
Indian J Pathol Microbiol. 2023 Nov 9. doi: 10.4103/ijpm.ijpm_1025_22. Online ahead of print.ABSTRACTBladder exstrophy is a rare congenital anomaly in which the urinary bladder develops outside the body. It may be part of the bladder epispadias-exstrophy-cloacal complex, which is a serious embryological defect where a spectrum of abnormalities involving the urinary tract, genital tract, musculoskeletal system, and intestinal tract is seen. Primary signet ring cell adenocarcinoma (PSRCA) arising in exstrophy of the urinary bladder is extremely rare with only a few cases reported in the literature. A 32-year-old man with con...
Source: Indian Journal of Pathology and Microbiology - February 23, 2024 Category: Pathology Authors: Gwendolyn Fernandes Gloria Khumanthem Nupur Harinkhede Amey Rojekar Source Type: research

Primary signet ring cell adenocarcinoma arising in exstrophy of the urinary bladder (epispadias-exstrophy complex)
Indian J Pathol Microbiol. 2023 Nov 9. doi: 10.4103/ijpm.ijpm_1025_22. Online ahead of print.ABSTRACTBladder exstrophy is a rare congenital anomaly in which the urinary bladder develops outside the body. It may be part of the bladder epispadias-exstrophy-cloacal complex, which is a serious embryological defect where a spectrum of abnormalities involving the urinary tract, genital tract, musculoskeletal system, and intestinal tract is seen. Primary signet ring cell adenocarcinoma (PSRCA) arising in exstrophy of the urinary bladder is extremely rare with only a few cases reported in the literature. A 32-year-old man with con...
Source: Indian Journal of Pathology and Microbiology - February 23, 2024 Category: Pathology Authors: Gwendolyn Fernandes Gloria Khumanthem Nupur Harinkhede Amey Rojekar Source Type: research

Primary signet ring cell adenocarcinoma arising in exstrophy of the urinary bladder (epispadias-exstrophy complex)
Indian J Pathol Microbiol. 2023 Nov 9. doi: 10.4103/ijpm.ijpm_1025_22. Online ahead of print.ABSTRACTBladder exstrophy is a rare congenital anomaly in which the urinary bladder develops outside the body. It may be part of the bladder epispadias-exstrophy-cloacal complex, which is a serious embryological defect where a spectrum of abnormalities involving the urinary tract, genital tract, musculoskeletal system, and intestinal tract is seen. Primary signet ring cell adenocarcinoma (PSRCA) arising in exstrophy of the urinary bladder is extremely rare with only a few cases reported in the literature. A 32-year-old man with con...
Source: Indian Journal of Pathology and Microbiology - February 23, 2024 Category: Pathology Authors: Gwendolyn Fernandes Gloria Khumanthem Nupur Harinkhede Amey Rojekar Source Type: research

Extramammary Paget ’s Disease of the Penis and Scrotum
AbstractExtramammary Paget ’s disease (EMPD) is an adenocarcinoma arising from the skin or skin appendages which is sometimes associated with an underlying malignancy. EMPD is most commonly seen in the vulva, followed by perianal region, and the male genitalia. In most cases, patient presents with eczematous lesion persisti ng for long duration. A 77-year-old gentleman had a history of chronic eczematous lesion over penis and scrotum for the last 10 years. Examination revealed an erythematous plaque like eczematous lesion over the penis and scrotum. Biopsy with IHC of lesion is suggestive of EMPD. Wide local excision of...
Source: Indian Journal of Surgical Oncology - January 23, 2024 Category: Cancer & Oncology Source Type: research

New EAU/ASCO guideline recommendations on sentinel node biopsy for penile cancer and remaining challenges from a nuclear medicine perspective
ConclusionOver the years, DSNB has evolved significantly, related to the dedicated efforts and innovations in nuclear medicine and subsequent clinical studies validating its efficacy. It is now strongly recommended for surgical staging among selected penile cancer patients. To optimise DSNB further, multidisciplinary collaborative research is required to improve SN identification for better diagnostic accuracy and fewer complications. (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - January 13, 2024 Category: Nuclear Medicine Source Type: research

Pathologically Confirmed Subcutaneous Fat and Lymphovascular Invasion of a Hypopigmented Area in Extramammary Paget Disease
We report a case of a 62-year-old male with EMPD that invaded the subcutaneous fat layer. He presented with a several-year history of a slowly expanding erythematous plaque with the hypopigmented area on the left penoscrotum. One month before presentation, the patient had undergone punch biopsy at another hospital and diagnosed with EMPD. He had no personal history of urogenital cancers. The patient was treated with Mohs micrographic surgery, and negative margins were achieved after four stages. The histopathologic findings revealed Paget cells scattered throughout the epidermis. At the hypopigmented area, Paget cells exte...
Source: Annals of Dermatology - December 7, 2023 Category: Dermatology Authors: Gyoo Huh Ga-Young Lee Yumin Chung Seung-Wan Chae Young-Jun Choi Source Type: research

Chronic myeloid leukemia with sleep-related painful erections as a first symptom: a case report
ConclusionWe considered that the occurrence of sleep-related painful erections was related to chronic myeloid leukemia and the case might be secondary sleep-related painful erections. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - November 30, 2023 Category: General Medicine Source Type: research