Early technique failure in peritoneal dialysis patients in a multi-ethnic Asian country
ConclusionTechnique failure in the first year of PD initiation occurs in one-fifth of PD patients and is associated with peripheral vascular disease and cause of end-stage kidney disease. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - September 24, 2020 Category: Urology & Nephrology Source Type: research

CERA conversion to darbepoetin alfa in 154 hemodialysis patients
ConclusionsWe conclude that, in this observational “real life” study, the two EPOs are to be considered as equivalent. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - September 24, 2020 Category: Urology & Nephrology Source Type: research

Daily physical activity in patients on chronic haemodialysis and its relation with fatigue and depressive symptoms
AbstractObjectiveFatigue and depressed mood are considered main impediments to physical activity in haemodialysis (HD) patients. A better understanding of their interrelationships is crucial to develop effective therapies. Moreover, measurement of daily physical activity (DPA) in HD patients is tricky, as it is usually assessed by subjective self-report questionnaires. Therefore, we aimed to objectively measure sponteanous DPA with motion sensors and to explore its relation with fatigue and depressive symptoms.MethodsDPA was assessed for seven consecutive days in 37 HD patients based on their daily step count measured with...
Source: International Urology and Nephrology - September 24, 2020 Category: Urology & Nephrology Source Type: research

Melatonin ingestion before intradialytic exercise improves immune responses in hemodialysis patients
AbstractPurposeThe present study aimed to investigate the effects of melatonin (MEL) intake on systemic inflammation and immune responses during intradialytic exercise.MethodsThirteen hemodialysis (HD) patients volunteered to participate in the current randomized-crossover study. Immunological responses were monitored in four HD sessions at different conditions: [Exercise (EX)  + MEL], [EX + Placebo (PLA)], [Control (CON) + MEL] and [CON + PLA]. MEL (3 mg) or PLA was ingested 1 h before starting exercise or the equivalent time in CON condition. Dur...
Source: International Urology and Nephrology - September 23, 2020 Category: Urology & Nephrology Source Type: research

Evaluation of the efficacy of sexual intercourse on distal ureteral stones in women: a prospective, randomized, controlled study
AbstractAimTo evaluate the efficacy of sexual intercourse in the expulsion of distal ureteric stones in women.Materials and methodsA total of seventy woman patients with distal ureteral or intramural stone were randomly divided into two groups. Group 1 included 35 patients who were advised to do sexual intercourse 3 –4 times/week with the administration of symptomatic treatment, and group 2 (control group) included 35 patients receiving symptomatic treatment only and were instructed not to do sexual intercourse or masturbation during the study. After 4 weeks follow up; the expulsion rate, need for analgesic and ...
Source: International Urology and Nephrology - September 23, 2020 Category: Urology & Nephrology Source Type: research

Malnutrition as a risk factor for cardiac valve calcification in patients under maintenance dialysis: a cross-sectional study
ConclusionAging, inflammation, low serum albumin to total proteins ratio and low phase angle values as indicators of malnutrition are predictors of severe CVC in end-stage renal disease patients on hemodialysis. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - September 22, 2020 Category: Urology & Nephrology Source Type: research

Glomerulosclerosis predicts poor renal outcome in patients with idiopathic membranous nephropathy
This study aimed to investigate the association between the proportion of glomerulosclerosis (focal segmental glomerulosclerosis and/or global glomerulosclerosis) and renal prognosis in patients with idiopathic membranous nephropathy (IMN).MethodsA retrospective analysis performed from January 2008 to December 2017 in the First Affiliated Hospital of Shenzhen University by renal biopsy confirmed 200 patients with IMN, and their clinical pathology and prognosis were compared. Patients were divided into three groups on the basis of glomerular sclerosis proportion tertiles: low (Tertile1 group, proportion of glomerulosclerosi...
Source: International Urology and Nephrology - September 22, 2020 Category: Urology & Nephrology Source Type: research

Correlation between laboratory parameters on admission and outcome of COVID-19 in maintenance hemodialysis patients
AbstractPurposeThis present study aims to investigate the relationship between laboratory parameters on admission and prognosis of coronavirus disease 2019 (COVID-19) in maintenance hemodialysis patients, as well as providing a theoretical basis for clinical evaluation of prognosis and corresponding intervention measures.MethodsRetrospective analysis was performed on the clinical data of 47 maintenance hemodialysis patients who infected with COVID-19 and admitted to our hospital. According to their clinical outcome, these patients were divided into a survival group (n = 38) and a fatality group (n =&th...
Source: International Urology and Nephrology - September 20, 2020 Category: Urology & Nephrology Source Type: research

Clinical characteristics and cost of hospital stay of octogenarians and nonagenarians in intensive care nephrology unit
ConclusionLength of nephrology intensive care stay, mortality rate and hospital cost did not differ for very elderly age groups, but mortality risk was higher for nonagenarians after discharge from hospital. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - September 19, 2020 Category: Urology & Nephrology Source Type: research

The effect of sodium exchange and dialytic biochemical parameters on blood pressure, arterial stiffness, and endothelial functions in patients with peritoneal dialysis
This study aimed to investigate the relationship between fluid and sodium excretion and blood pressure, echocardiographic parameters, and arterial stiffness in peritoneal dialysis (PD) patients and to evaluate the effect of sodium excretion on patients ’ survival.MethodThis study was conducted as a single-centered, prospective study in the Department of Nephrology in Erciyes University. The patients included in the study were followed up for 3 years. Seventy PD patients were included in the study. We recorded demographic characteristics, biochemical parameters, urine and peritoneal ultrafiltration volumes, peritoneal...
Source: International Urology and Nephrology - September 18, 2020 Category: Urology & Nephrology Source Type: research

Renal function is associated with plasma trimethylamine-N-oxide, choline, l -carnitine and betaine: a pilot study
ConclusionCombinations of TMAO and its precursors were associated with glomerular function and might be utilized in evaluation of CKD. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - September 18, 2020 Category: Urology & Nephrology Source Type: research

Corticosteroids could improve the renal outcome of IgA nephropathy with moderate proteinuria
AbstractBackgroundThe specific treatment regimens of IgA nephropathy (IgAN) patients with moderate proteinuria (1.0 –3.5 g/day) remain controversial. The purpose of this study was to explore the optimized therapeutic regimen for IgAN patients through analyzing the clinical data.MethodsA retrospective study was conducted, 449 patients with biopsy-proven IgAN were enrolled. Patients were divided into three groups according to proteinuria levels: urine protein 1.0 –1.5 g/day (UP1,n = 111), urine protein 1.5–2.5 g/day (UP2,n = 213), urine protein 2.5–3.5 g...
Source: International Urology and Nephrology - September 17, 2020 Category: Urology & Nephrology Source Type: research

Sex disparities in IgA nephropathy: a retrospective study in Chinese patients
AbstractAimThe aim of this study was to explore the effect of sex on the clinicopathological features and long-term outcomes of IgAN patients.MethodsA total of 1096 adult IgAN patients were divided into male and female groups. Clinicopathological features and risk factors of IgAN patients of different genders were contrasted. The primary endpoint was the combined endpoint of a 50% reduction in estimated glomerular filtration rate (eGFR) and/or end stage renal disease (ESRD: eGFR  
Source: International Urology and Nephrology - September 17, 2020 Category: Urology & Nephrology Source Type: research

Kidney biopsy in the elderly: diagnostic adequacy and yield
AbstractPurposeThe number of kidney biopsies (KB) performed in elderly patients has been increasing. Safety and usefulness of elderly KB have been well established, whereas much less is known about diagnostic adequacy and yield in this patient population.MethodsWe performed a retrospective study of KBs in 428 patients from April 2015 to December 2017 at an academic institution. We compared KB from 50 patients aged over 64 (elderly) with KB from 378 patients aged between 18 and 64.ResultsGender ratio, body mass index, systolic and diastolic BP, creatinine values, incidences of AKI at the time of biopsy, INR/aptt values, and...
Source: International Urology and Nephrology - September 17, 2020 Category: Urology & Nephrology Source Type: research

Rituximab for the management of idiopathic membranous nephropathy: a meta-analysis
AbstractPurposeThe aim of this study was to evaluate the efficacy of rituximab therapy in the management of idiopathic membranous nephropathy (IMN).MethodsAfter literature search, data from eligible studies were used to perform random-effects meta-analyses to estimate remission rates and changes in proteinuria at the latest follow-up after rituximab therapy. The outcomes were used for metaregression to identify the factors affecting the efficacy of rituximab.ResultsTwenty-one studies were included in the analysis (602 patients; age 50  years [95% CI 46.8, 53.3]; 30% females [95% CI 23, 31]). Follow-up duration was 20....
Source: International Urology and Nephrology - September 17, 2020 Category: Urology & Nephrology Source Type: research

A novel NPHS1 mutation associated with temporary elevation of maternal serum alfa-fetoprotein and late onset of proteinuria
(Source: International Urology and Nephrology)
Source: International Urology and Nephrology - September 17, 2020 Category: Urology & Nephrology Source Type: research

Thrombocytopenia in a home hemodialysis patient with NxStage system
(Source: International Urology and Nephrology)
Source: International Urology and Nephrology - September 17, 2020 Category: Urology & Nephrology Source Type: research

Bladder venous malformation
(Source: International Urology and Nephrology)
Source: International Urology and Nephrology - September 17, 2020 Category: Urology & Nephrology Source Type: research

Long-term outcomes of ulcerative interstitial cystitis after complete transurethral resection with therapeutic hydrodistention
AbstractPurposeWe analyzed the long-term efficacy of simultaneous transurethral resection (TUR) and therapeutic hydrodistention in patients with ulcerative interstitial cystitis (IC) who did not experience recurrence on long-term follow-up.MethodsWe studied 132 female patients (mean age  = 56.45 ± 11.56 years) who underwent TUR followed by hydrodistention to treat ulcerative IC between January 2010 and January 2017, and who were available for follow-up, for more than 36 months (mean = 52.3 ± 10.51 months). Of the 132 patients, those who di...
Source: International Urology and Nephrology - September 14, 2020 Category: Urology & Nephrology Source Type: research

Simultaneous antegrade and retrograde endourological approach in Galdakao-modified supine Valdivia position for the management of missed stents associated with complex renal stones: a non-randomized pilot study
ConclusionSimultaneous antegrade and retrograde renal approach in the GMSVP is safe and effective in the management of missed DJ stents with a complex stone burden. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - September 14, 2020 Category: Urology & Nephrology Source Type: research

Over-diagnosed prostate cancer in solid organ recipients: lessons from the last 3 decades
ConclusionSystematic screening in male SOTR after 50  years old could not be recommended. In the last 3 decades, we diagnosed too many low-risk prostate cancers strongly increasing the SIR but failing to decrease prostate cancer related mortality. SOTR should undergo individual screening with prior MRI when PSA rates are high. Management should not b e different from that of the general population. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - September 14, 2020 Category: Urology & Nephrology Source Type: research

Urolithiasis in complicated inflammatory bowel disease: a comprehensive analysis of urine profile and stone composition
ConclusionPatients with IBD with TPC and kidney stones have a low urine volume and low urine citrate as main risk factors for kidney stone formation. As seen in the general population, calcium oxalate is the most common stone composition. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - September 11, 2020 Category: Urology & Nephrology Source Type: research

Laparoendoscopic radical prostatectomy (LRP): stepwise transition from multi-site to single-site with the aid of the transurethral port
AbstractPurposeTo describe our initial experience with laparoendoscopic radical prostatectomy (LRP) and a stepwise transition towards transurethral assisted laparoendoscopic single-site RP (TU-LESS RP).Patients and methodsFrom Jan. 2007 to Dec. 2016, 195 patients underwent RP, of which 89 patients were performed by LRP (Group A), 106 by TU-LESS RP (Group B). The peri-operative data were collected and analyzed. All data referring to patient demographics, surgery, pathology, and peri-operative outcomes were recorded. The cosmetic result was investigated by the Patient Scar Assessment Questionnaire (PSAQ). Analysis of varianc...
Source: International Urology and Nephrology - September 9, 2020 Category: Urology & Nephrology Source Type: research

Acute kidney injury in COVID-19: a case-report
(Source: International Urology and Nephrology)
Source: International Urology and Nephrology - September 8, 2020 Category: Urology & Nephrology Source Type: research

Clinicopathologic features, outcomes, and prognostic factors of testicular sarcoma: a population-based study
AbstractPurposeTo describe clinical characteristics and identify prognostic factors among men with testicular sarcoma, and to compare survival with other testicular cancers.MethodsThe surveillance, epidemiology, and end results (SEER) database (1975 –2016) was queried to identify adults with testicular sarcoma. Multivariable Cox proportional hazards, Fine and Gray competing-risks regression, propensity score matching, and Kaplan–Meier analyses were used.Results230 men were included in this study. Median age at diagnosis was 58  years (range 18–94), and median OS was 10.3 years. Patients with tum...
Source: International Urology and Nephrology - September 7, 2020 Category: Urology & Nephrology Source Type: research

Comparison of outcomes of urgent-start and conventional-start peritoneal dialysis: a single-centre experience
ConclusionUrgent-start PD was associated with higher risks of dialysate leak and peritonitis but comparable technique and patient survival compared to conventional-start PD. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - September 7, 2020 Category: Urology & Nephrology Source Type: research

Oxalobacter formigenes reduce the risk of kidney stones in patients exposed to oral antibiotics: a case –control study
AbstractThis is the first prospective study to investigate the association between kidney stones, bone mineral density, serum testosterone, colon cancer andO. formigenes colonization. 40 kidney stone patients and 85 controls were enrolled.O. formigenes colonization was established. BMD was examined from T- and Z-scores using dual energy absorptiometry.O. formigenes was found in 28 of 40 cases and 80 of 85 controls. BMD was significantly reduced in patients (p  
Source: International Urology and Nephrology - September 2, 2020 Category: Urology & Nephrology Source Type: research

Immediate preoperative renal artery embolization in the resection of complex renal tumors (UroCCR-48 Reinbol study)
AbstractPurposeWe evaluated the feasibility and outcomes of immediate preoperative renal artery embolization (IPRAE) before complex nephrectomy for locally advanced RCC  ± inferior vena cava thrombus (IVCT).MethodsA comparative retrospective (2007 –2017) multicenter study which included 145 patients with locally advanced RCC ± IVCT: 99 radical nephrectomies vs. 46 radical nephrectomies with IPRAE identified in the prospective UroCCR national database (CNIL DR 2013–206; NCT03293563). IPRAE was performed under local anesthesia the day of nephrectomy (
Source: International Urology and Nephrology - September 2, 2020 Category: Urology & Nephrology Source Type: research

Comparison of outcomes of Burch colposuspension and transobturator tape and single incision needleless procedures (DynaMesh ® -SIS minor) for the surgical treatment of female stress urinary incontinence patients who underwent combined pelvic reconstructive surgery or hysterectomy
ConclusionsBoth Burch and TOT are effective procedures in patients with SUI who require additional pelvic surgeries. Although surgical outcomes of SIS procedure in patients with SUI who underwent concomitant pelvic surgeries in our study were not promising, further studies with SIS are needed to clarify these observations. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - September 1, 2020 Category: Urology & Nephrology Source Type: research

Long-term chronological changes in urination status of patients who underwent ileal neobladder reconstruction at a single institution
ConclusionsAlthough long-term urinary function with ONB demonstrated acceptable results, dysfunctional voiding was observed  >  10 years after surgery. Thus, the changes in long-term urinary function should be considered when deciding ONB. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - September 1, 2020 Category: Urology & Nephrology Source Type: research

Genome-wide association study of nephrolithiasis in an Eastern European population
ConclusionThis study is the largest kidney stone-related GWAS reported in an Eastern European population and the first GWAS performed in a Romanian population to investigate the genetic risk factors for nephrolithiasis. We identified several loci that warrant further investigation for a better understanding of this highly heritable condition. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - August 31, 2020 Category: Urology & Nephrology Source Type: research

Assessment of cardiac structure and function in kidney failure: understanding echocardiography and magnetic resonance imaging for the nephrologist
AbstractCardiovascular disease is the leading cause of death in patients with kidney failure or on chronic dialysis. Patients on chronic dialysis have a 10- to 50-fold increased risk of sudden cardiac death compared to patients with normal kidney function. Adverse changes in cardiac structure and function may not manifest with clinical symptoms in patients with kidney failure and, therefore, pose a challenge in identifying cardiac dysfunction early. Fortunately, there are multi-modality cardiac imaging techniques available, including echocardiography and cardiac magnetic resonance imaging, that can help our understanding o...
Source: International Urology and Nephrology - August 31, 2020 Category: Urology & Nephrology Source Type: research

Exercise interventions improve depression and anxiety in chronic kidney disease patients: a systematic review and meta-analysis
AbstractPurposeThis systematic review examined the effects of exercise interventions on depression and anxiety in chronic kidney disease patients.MethodsElectronic searches were conducted between August 2019 and February 2020 at PubMed, MEDLINE, Web of Science, EBSCO, Scopus, LILACS, EMBASE, Physiotherapy Evidence Database, and Cochrane Library databases. Original clinical trial studies that examined the effects of exercise on depression and anxiety in chronic kidney disease patients, stages 3 –5, were included. A total of eight studies were included in the systematic review after applying the eligibility criteria, a...
Source: International Urology and Nephrology - August 31, 2020 Category: Urology & Nephrology Source Type: research

Efficacy and safety of alvimopan use in benign urinary tract reconstruction
ConclusionThe use of perioperative alvimopan in benign abdominal urinary tract reconstruction expedited return of bowel function and decreased length of stay compared to a matched cohort of untreated patients. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - August 31, 2020 Category: Urology & Nephrology Source Type: research

Tolvaptan treatment in hyponatremia due to the syndrome of inappropriate secretion of antidiuretic hormone (SIADH): effects on survival in patients with cancer
This study included oncology patients who were hospitalized at two oncology centers between January 1, 2016 and December 31, 2019 for hyponatremia (sodium levels    0.05). In the TpST group, recovery days of the hyponatremia after treatment and the length of hospital stay was shorter and hyponatremia symptoms and hospital complications were less frequent compared to the ST group (p 
Source: International Urology and Nephrology - August 31, 2020 Category: Urology & Nephrology Source Type: research

Quality indicators of vascular access procedures for hemodialysis
AbstractImproved quality of surgical procedures can minimize complications, the morbidity and mortality of patients, and in addition decrease costs. Quality indicators in angioaccess surgery are, however, not clearly defined. The aim of this review article is therefore to find the most important factors affecting quality in vascular access procedures. Even though autogenous arteriovenous fistula has been recognized as the best vascular access for hemodialysis, the high percentage of unsuccessful attempts associated with it raises the question about quality assessment in angioaccess procedures. Unfortunately, quality indica...
Source: International Urology and Nephrology - August 31, 2020 Category: Urology & Nephrology Source Type: research

Mobilization of a peritoneal dialysis catheter using an extra-corporeal magnet: preliminary experimental phase study
ConclusionIn this preliminary analysis, the use of an extra-corporeal magnet to move the Mag-Cath was feasible, with a low grade of difficulty, and individuals with different levels of expertise could perform it. Further studies in human subjects are needed to evaluate the clinical applicability of the Mag-Cath properly. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - August 31, 2020 Category: Urology & Nephrology Source Type: research

Determinants of adequate lymph  node dissection following neoadjuvant chemotherapy in patients with urothelial muscle-invasive bladder cancer: results from the National Cancer Database
AbstractPurposeRecent literature has separately identified multiple determinants of the use of neoadjuvant chemotherapy (NAC) and adherence to pelvic lymph  node dissection (PLND) guidelines in the management of non-metastatic bladder cancer. However, such NAC/PLND analyses tend not to account for the other modality, despite the fact that NAC may impact the extent of dissectible lymph nodes. We aimed to determine the predictors of adequate PLND in pat ients with non-metastatic urothelial muscle-invasive bladder cancer (MIBC) undergoing radical cystectomy (RC) following receipt of NAC.MethodsWe queried the National Can...
Source: International Urology and Nephrology - August 31, 2020 Category: Urology & Nephrology Source Type: research

Comparison of ischemic and ischemic/reperfused kidney injury via clamping renal artery, vein, or pedicle in anesthetized rats
ConclusionThe transmission of high arterial pressure into renal microvessels and rupturing of their walls during venous-clamping augment, but the retrograde blood flow from veins into kidney during artery clamping attenuates induction of renal tissue injury with respect to pedicle clamping not only at the ischemic period but also at the early reperfusion period and along with the proportional development of renal dysfunctions. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - August 31, 2020 Category: Urology & Nephrology Source Type: research

A new technique for ureteral reconstruction using lingual mucosa grafts in a beagle model
AbstractPurposeTo investigate the feasibility of ureteral reconstruction using lingual mucosa graft (LMG) and evaluate the histological changes of the engrafted LMG in beagles.MethodsTwelve male beagle dogs were randomly divided into groups A, B and C (n = 4). A ventral ureteral defect was created by excising half of the ureteral wall. The length of the defect was 3 cm, 6 cm, and 10 cm in groups A, B, and C, respectively. The LMGs were harvested and employed to repair the ureteral defects in onlay fashion. Two dogs per group were sacrificed after 6 months, with additional two dogs per grou...
Source: International Urology and Nephrology - August 30, 2020 Category: Urology & Nephrology Source Type: research

Evaluation of the role of reflux pattern in Color Doppler Ultrasound on spermogram improvement after varicocelectomy
ConclusionPatients with a higher reflex grade, particularly enhancing pattern, will most benefit from the surgical correction of varicocele. These findings suggest reflux pattern as a promising prognostic factor for a favorable outcome after varicocelectomy. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - August 29, 2020 Category: Urology & Nephrology Source Type: research

Laparoscopic pyeloplasty as an alternative to nephrectomy in adults with poorly functioning kidneys due to ureteropelvic junction obstruction
ConclusionsLP in adult patients with UPJO and poor function kidneys is an effective and safe procedure. DRF recovery is seen in a minority of the patients; however, LP is an alternative to nephrectomy. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - August 29, 2020 Category: Urology & Nephrology Source Type: research

Analysis of the YouTube videos on pelvic floor muscle exercise training in terms of their reliability and quality
This study was carried out on the descriptive model in order to evaluate the content, reliability and quality of the videos on YouTube related to pelvic floor muscle exercise training. “Pelvic floor muscle exercise” was searched on YouTube in English in March 2020, and a total of 107 videos were watched. Quality Criteria for Consumer Health Information (DISCERN) survey was used to analyze the videos in terms of their reliabilities, and Global Quality Score (GQS) was used to ev aluate their qualities.ResultsWhen the contents of 59 videos included in the study were examined, it was determined that 52 of them cont...
Source: International Urology and Nephrology - August 29, 2020 Category: Urology & Nephrology Source Type: research

RE: Renal protective effect of N -acetylcysteine with stepwise ramping voltage against extracorporeal shock wave lithotripsy-induced renal injury: a prospective randomized trial from Desoky et al
(Source: International Urology and Nephrology)
Source: International Urology and Nephrology - August 29, 2020 Category: Urology & Nephrology Source Type: research

Does multidetector computed tomographic urography (MDCTU) T staging classification correspond with pathologic T staging in upper tract urothelial carcinoma?
ConclusionMDCTU T stage classification may be relatively accurate for the detection and staging of UTUC correspondence with a pathologic stage. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - August 28, 2020 Category: Urology & Nephrology Source Type: research

Regional brain atrophy in overactive bladder syndrome: a voxel based morphometry study
ConclusionsPatients with OAB have abnormal GMV in brain regions localized within the brain-bladder control network. It deepens our understanding of the structural changes in the brain area of the network. The patterns of structural reorganization in patients with OAB may provide useful information in the neuropathological mechanisms of the OAB. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - August 26, 2020 Category: Urology & Nephrology Source Type: research

Decreased insulin-like growth factor-1 (IGF-1) concentration correlates with reduced left-ventricle ejection fraction (LVEF) in hemodialysis patients
AbstractPurposeThe main purpose of this study is to determine the correlation between the serum IGF-1 concentration and certain cardiac indexes in hemodialysis patients.MethodsThe study was conducted at the Clinical Center of Montenegro and three regional hemodialysis centers. The echocardiographic studies were performed the day after the hemodialysis sessions. Blood samples were taken before dialysis for the measurement of IGF1 and PTH.ResultsA total of 102 patients were divided into two groups according to their left-ventricular ejection fraction (EF). Patients in the group with the higher EF had higher IGF-1 concentrati...
Source: International Urology and Nephrology - August 26, 2020 Category: Urology & Nephrology Source Type: research

Validation of the TWIST score for testicular torsion in adults
ConclusionThe TWIST Score is valid for the diagnosis of Testicular Torsion in adults, presenting a PPV of 90% for a cutoff of 5 points and 100% for six points. In all patients with a score of 2 or less, the disease could be safely excluded (100% NPV). (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - August 25, 2020 Category: Urology & Nephrology Source Type: research

Accuracy of ultrasound vs computed tomography scan for upper urinary tract malignancies and development of a risk-based diagnostic algorithm for haematuria in a UK tertiary centre
AbstractPurposeThere is no consensus across guidelines on a diagnostic algorithm for upper urinary tract (UUT) evaluation following presentation with haematuria. Our aim is to compare the diagnostic accuracy of ultrasound (USS) compared to CT-scan for UUT malignancies and also determine the considerations important for a risk-based diagnostic protocol for haematuria.MethodsWe reviewed our ‘haematuria clinic’ database to identify patients who had both USS and CT-scan for UUT evaluation between September 2015 and August 2017, and calculated the diagnostic accuracy of these imaging modalities for histologically co...
Source: International Urology and Nephrology - August 25, 2020 Category: Urology & Nephrology Source Type: research

The impact of multidisciplinary team conferences in urologic cancer in a tertiary hospital
ConclusionsMDT conferences had an important impact in the management of 38.2% of cases. Therefore, all patients with urologic malignancies should be referred to MDT review to ensure optimal clinical care. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - August 20, 2020 Category: Urology & Nephrology Source Type: research