Endogenous testosterone density predicts unfavorable disease at final pathology in intermediate risk prostate cancer
AbstractObjectiveTo test the hypothesis that endogenous testosterone (ET) density could be associated with tumor load (TL) in patients with intermediate risk (IR) prostate cancer (PCa).Materials and methodsEndogenous testosterone density (ETD, ratio between ET and prostate volume [PV]), biopsy positive cores density (BPCD, the ratio between the number of positive cores and PV) and prostate-specific antigen density (PSAD, ratio between total PSA and PV) were retrospectively evaluated on a prospectively collected data on 430 patients with IR PCa submitted to radical prostatectomy (RP). Tumor load (TL) was measured as the per...
Source: International Urology and Nephrology - November 19, 2021 Category: Urology & Nephrology Source Type: research

Gleason grade accuracy of transperineal and transrectal prostate biopsies in MRI-na ïve patients
ConclusionThis study suggests TP approach to prostate biopsies result in improved histological grade accuracy in men whom MRI is not available, even after controlling for number of cores. TP approach also resulted in less upgrading for lesions in the anterior and apical prostate compared to TR. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - November 19, 2021 Category: Urology & Nephrology Source Type: research

Impact of testicular delivery and vasal vein ligation on clinical outcomes in men undergoing microsurgical varicocelectomy
AbstractPurposeTo assess the impact of microsurgical varicocelectomy technique on clinical outcomes.MethodsMen diagnosed with varicocele between 2017 and 2020 were reviewed. We included men who underwent microsurgical varicocelectomy by two high-volume surgeons who differed in surgical technique: Method (1) testicular delivery with gubernacular vein ligation, and ligation of vasal veins  >  2.5 mm; Method (2) no delivery and ligation of dilated vasal veins in cases of recurrence. Post-operative changes for semen parameters, DNA fragmentation, and serum testosterone were evaluated for each technique an...
Source: International Urology and Nephrology - November 19, 2021 Category: Urology & Nephrology Source Type: research

Partial versus total adrenalectomy for pheochromocytoma: a population-based comparison of outcomes
ConclusionsIn this first population-level comparison of outcomes among patients with pheochromocytoma undergoing PA and those undergoing TA, we found no long-term differences in any survival metric between groups. PA circumvents the need for lifelong corticoid replacement therapy and remains a promising option for patients with bilateral or recurrent pheochromocytoma. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - November 19, 2021 Category: Urology & Nephrology Source Type: research

The effect of heated lidocaine gel on pain reduction during transrectal ultrasound-guided prostate biopsy: a randomized-controlled study
AbstractPurposeTo determine whether intrarectal local anesthesia (IRLA) with heated lidocaine gel provides pain reduction during transrectal ultrasound (TRUS)-guided prostate biopsy.MethodsWe conducted a randomized-controlled study with 153 participants who underwent TRUS-guided, systematic 12-core prostate biopsy from May 2018 to June 2019. These participants were divided into three test groups. Before prostate biopsy, group A (51 patients) received no local anesthesia, group B (51 patients) received IRLA with 20  mL 2% lidocaine gel stored at room temperature, and group C (51 patients) received IRLA with heated (40 ...
Source: International Urology and Nephrology - November 19, 2021 Category: Urology & Nephrology Source Type: research

The prognostic value of lymph node ratio in comparison to positive lymph node count in penile squamous cell carcinoma
ConclusionLNR was a better predictor for long-term prognosis than PLNC in patients with penile squamous cell carcinoma. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - November 19, 2021 Category: Urology & Nephrology Source Type: research

Endogenous testosterone density predicts unfavorable disease at final pathology in intermediate risk prostate cancer
AbstractObjectiveTo test the hypothesis that endogenous testosterone (ET) density could be associated with tumor load (TL) in patients with intermediate risk (IR) prostate cancer (PCa).Materials and methodsEndogenous testosterone density (ETD, ratio between ET and prostate volume [PV]), biopsy positive cores density (BPCD, the ratio between the number of positive cores and PV) and prostate-specific antigen density (PSAD, ratio between total PSA and PV) were retrospectively evaluated on a prospectively collected data on 430 patients with IR PCa submitted to radical prostatectomy (RP). Tumor load (TL) was measured as the per...
Source: International Urology and Nephrology - November 18, 2021 Category: Urology & Nephrology Source Type: research

Mutual effect modification between adiponectin and HDL as risk factors of cardiovascular events in Type 2 diabetes individuals: a cohort study
ConclusionOur results are coherent with the hypothesis that HDL cholesterol might play a pivotal role in the interpretation of the association between adiponectin and the risk of adverse CV outcomes in this population. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - November 18, 2021 Category: Urology & Nephrology Source Type: research

Predictive value of preprocedural albuminuria for contrast-induced nephropathy non-recovery in patients undergoing percutaneous coronary intervention
AbstractObjectiveThe present study investigated the predictive value of albuminuria for contrast-induced nephropathy (CIN) non-recovery in patients undergoing percutaneous coronary intervention (PCI).MethodsWe retrospectively enrolled 550 consecutive patients inflicted with CIN after PCI and reassessing kidney function among 1  week–12 months between January 2012 and December 2018. Patients were stratified into three groups according to urine albumin: negative group (urine dipstick negative), trace group (urine dipstick trace) and positive group (urine dipstick ≥ 1 +). The primary ou...
Source: International Urology and Nephrology - November 18, 2021 Category: Urology & Nephrology Source Type: research

Tumor cell PD-L1 expression is a strong predictor of unfavorable prognosis in immune checkpoint therapy-naive clear cell renal cell cancer
AbstractBackgroundPD-L1 expression predicts response to immune checkpoint inhibitors in renal cell carcinomas (RCC), but has also been suggested to be linked to poor patient outcome.MethodsWe analyzed PD-L1 in  >  1400 RCC in a tissue microarray format by immunohistochemistry. Results were compared with histological tumor type, parameters of cancer aggressiveness, and intratumoral CD8+ cytotoxic cells.ResultAt a cut-off level of 5% PD-L1 positive tumor cells, PD-L1 positivity was seen in 6.3% of 633 clear cell RCC (ccRCC), 18.2% of 165 papillary RCC, 18.8% of 64 chromophobe RCC, and 41.7% of 103 oncoc...
Source: International Urology and Nephrology - November 18, 2021 Category: Urology & Nephrology Source Type: research

Chronic kidney disease progression in aged patients
In this study, we investigated the progression of CKD and related factors in aged patients.MethodsThis was a retrospective study including 334 patients over 80  years of age that were diagnosed with stage 3–4 CKD at our CKD clinic. CKD progression was assessed as an annual decline in the estimated glomerular filtration rate (eGFR). Comorbidities were globally categorized with the Charlson comorbidity index (CCI), but diabetes mellitus, hypertension, and cardiac morbidities were evaluated separately. Patients were grouped as either ‘progression to end-stage renal disease (ESRD)’ or ‘others&rsquo...
Source: International Urology and Nephrology - November 18, 2021 Category: Urology & Nephrology Source Type: research

Gleason grade accuracy of transperineal and transrectal prostate biopsies in MRI-na ïve patients
ConclusionThis study suggests TP approach to prostate biopsies result in improved histological grade accuracy in men whom MRI is not available, even after controlling for number of cores. TP approach also resulted in less upgrading for lesions in the anterior and apical prostate compared to TR. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - November 18, 2021 Category: Urology & Nephrology Source Type: research

Prevalence of non-alcoholic fatty liver disease among patients with non-diabetic chronic kidney disease detected by transient elastography
AbstractPurposeNon-alcoholic fatty liver disease (NAFLD) shares a close relationship with cardiovascular morbidity and mortality. The purpose of this study is to evaluate the frequency of NAFLD in the patients with non-diabetic chronic kidney disease (CKD).MethodsThis cross-sectional study included 80 patients with non-diabetic CKD, of which, 50 patients were on hemodialysis (HD) and 30 patients had CKD stage G3 –5 not on dialysis. These patients were randomly selected from Ain Shams University Hospitals, Cairo, Egypt. Patients with diabetes mellitus, obesity, alcohol intake, viral hepatitis, or drug-induced liver st...
Source: International Urology and Nephrology - November 18, 2021 Category: Urology & Nephrology Source Type: research

Incidence of death from kidney diseases among cancer patients: a US population-based analysis
ConclusionThe risk of death from kidney diseases is increasing among cancer survivors recently. Nephrologists should be actively involved in certain facets of cancer treatment, and provide effective nephrology care, especially for elderly patients with black race, higher grade, and poorer disease stage. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - November 18, 2021 Category: Urology & Nephrology Source Type: research

The outcome of patients with myocardial infarction with non-obstructive coronary arteries (MINOCA) and impaired kidney function: a 3-year observational study
In this study, 178 patients were initially diagnosed with MINOCA over a period of 3  years at the Department of Invasive Cardiology of the University Clinical Hospital in Białystok. The value of estimated glomerular filtration rate (eGFR) was calculated for all patients. The patients were divided into 2 groups depending on the value of eGFR: group 1—53 patients with impaired ki dney function (eGFR 
Source: International Urology and Nephrology - November 18, 2021 Category: Urology & Nephrology Source Type: research

Impact of testicular delivery and vasal vein ligation on clinical outcomes in men undergoing microsurgical varicocelectomy
AbstractPurposeTo assess the impact of microsurgical varicocelectomy technique on clinical outcomes.MethodsMen diagnosed with varicocele between 2017 and 2020 were reviewed. We included men who underwent microsurgical varicocelectomy by two high-volume surgeons who differed in surgical technique: Method (1) testicular delivery with gubernacular vein ligation, and ligation of vasal veins  >  2.5 mm; Method (2) no delivery and ligation of dilated vasal veins in cases of recurrence. Post-operative changes for semen parameters, DNA fragmentation, and serum testosterone were evaluated for each technique an...
Source: International Urology and Nephrology - November 18, 2021 Category: Urology & Nephrology Source Type: research

Partial versus total adrenalectomy for pheochromocytoma: a population-based comparison of outcomes
ConclusionsIn this first population-level comparison of outcomes among patients with pheochromocytoma undergoing PA and those undergoing TA, we found no long-term differences in any survival metric between groups. PA circumvents the need for lifelong corticoid replacement therapy and remains a promising option for patients with bilateral or recurrent pheochromocytoma. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - November 18, 2021 Category: Urology & Nephrology Source Type: research

Discovery of potential biomarkers in acute kidney injury by ultra-high-performance liquid chromatography-tandem quadrupole time-of-flight mass spectrometry (UPLC-Q/TOF –MS)
Conclusion2-S-glutathionyl glutathione acetate, 5-l-Glutamyl-taurine, andl-Phosphoarginine were associated with AKI patients, which could be selected as potential biomarkers to predicate AKI disease. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - November 18, 2021 Category: Urology & Nephrology Source Type: research

The effect of heated lidocaine gel on pain reduction during transrectal ultrasound-guided prostate biopsy: a randomized-controlled study
AbstractPurposeTo determine whether intrarectal local anesthesia (IRLA) with heated lidocaine gel provides pain reduction during transrectal ultrasound (TRUS)-guided prostate biopsy.MethodsWe conducted a randomized-controlled study with 153 participants who underwent TRUS-guided, systematic 12-core prostate biopsy from May 2018 to June 2019. These participants were divided into three test groups. Before prostate biopsy, group A (51 patients) received no local anesthesia, group B (51 patients) received IRLA with 20  mL 2% lidocaine gel stored at room temperature, and group C (51 patients) received IRLA with heated (40 ...
Source: International Urology and Nephrology - November 18, 2021 Category: Urology & Nephrology Source Type: research

The prognostic value of lymph node ratio in comparison to positive lymph node count in penile squamous cell carcinoma
ConclusionLNR was a better predictor for long-term prognosis than PLNC in patients with penile squamous cell carcinoma. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - November 18, 2021 Category: Urology & Nephrology Source Type: research

The impact of marital and socioeconomic status on quality of life and physical activity in patients with chronic kidney disease
ConclusionIn ambulatory patients with CKD stage 4 –5, being married or having a permanent partner and a high educational level had positive impacts on mental QOL. Higher educational level was also associated with better physical QOL. The presented inequality in QOL should be considered in communications, care and treatments in clinical practice. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - November 18, 2021 Category: Urology & Nephrology Source Type: research

Impact of small and dense low-density lipoprotein (sd-LDL)on contrast-induced acute kidney injury in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention
AbstractObjectiveTo investigate the impact of serum small and dense low-density lipoprotein (sd-LDL) on contrast-induced acute kidney injury (CI-AKI) after emergency percutaneous coronary intervention (PCI) in patients with acute ST-segment elevation myocardial infarction (STEMI).MethodFrom November 2019 to August 2020, 352 patients with STEMI who underwent primary PCI were recruited consecutively. Patients were divided into CI-AKI group (n = 71) and non-CI-AKI group (n = 281). CI-AKI was defined as an increase in serum creatinine (≥ 25% or ≥ 0.5 mg/dL) from basel...
Source: International Urology and Nephrology - November 18, 2021 Category: Urology & Nephrology Source Type: research

Sex modulates the association of radial artery augmentation index with renal function decline in individuals without chronic kidney disease
ConclusionThe rAI might help screen for those at high risk of early rapid RFD in women without CKD. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - November 18, 2021 Category: Urology & Nephrology Source Type: research

Is bladder preservation safe? The oncology outcomes of patients after 2-sided radical nephroureterectomies due to bilateral upper urinary tract urothelial carcinomas
ConclusionsRisk of cancer recurrence in the residual bladder is high, but does not affect survival outcomes. The highest UTUC stage plays a significant role in cancer-specific survival. With a careful patient surveillance, bladder preservation may be reasonable in patients with bilateral UTUC preparing for 2-sided RNUs. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - November 16, 2021 Category: Urology & Nephrology Source Type: research

The protective effect of manganese superoxide dismutase from thermophilic bacterium HB27 on hydrochloric acid-induced chemical cystitis in rats
ConclusionsIntravesical instillation of Tt-SOD provides protective effects against HCl-induced cystitis. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - November 16, 2021 Category: Urology & Nephrology Source Type: research

Cancer-specific mortality after radical prostatectomy vs external beam radiotherapy in high-risk Hispanic/Latino prostate cancer patients
ConclusionWithout the use of strictest adjustment for population differences, NCCN high-risk Hispanic/Latino prostate cancer patients appear to benefit more of RP than EBRT. However, after strictest adjustment for baseline patient and tumor characteristics between RP and EBRT cohorts, the apparent CSM benefit of RP is no longer statistically significant. In consequence, in Hispanic/Latino NCCN high-risk patients, either treatment modality results in similar CSM outcome. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - November 16, 2021 Category: Urology & Nephrology Source Type: research

Risk factors for failure of long-term dutasteride add-on treatment to alpha-adrenergic antagonist for patients with lower urinary tract symptoms and benign prostatic enlargement
AbstractPurposeTo identify the clinical factors resulting in the failure of dutasteride add-on treatment to alpha-adrenergic antagonist for patients with lower urinary tract symptoms and benign prostatic enlargement (BPE).MethodsWe retrospectively surveyed the patient cohort who had been enrolled in the study of dutasteride add-on treatment to alpha-adrenergic antagonist from December 2009 to November 2011. Treatment failure was defined as receiving surgery for BPE or requiring intermittent catheterization or permanent bladder catheter for urinary retention or huge postvoid residual urine. Clinical parameters before dutast...
Source: International Urology and Nephrology - November 12, 2021 Category: Urology & Nephrology Source Type: research

Correction to: Changes before and after COVID-19 pandemic on the personal hygiene behaviors and incidence of peritonitis in peritoneal-dialysis patients: a multi-center retrospective study
(Source: International Urology and Nephrology)
Source: International Urology and Nephrology - November 8, 2021 Category: Urology & Nephrology Source Type: research

Mortality-based definition of renal hyperfiltration in middle-aged men: a 35-year cohort from Finland
ConclusionThe burden of increased eGFR within what is still considered normal eGFR category was highly underestimated. RHF ’s eGFR values had a U-shaped association with the risk of overall mortality. A more uniform consensual definition of RHF is needed, as higher to normal eGFR values that are not without consequences. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - November 3, 2021 Category: Urology & Nephrology Source Type: research

High mobility group box 1 and homocysteine as preprocedural predictors for contrast-induced acute kidney injury after percutaneous coronary artery intervention
AbstractPurposeHigh mobility group box 1 (HMGB1) and homocysteine (Hcy) play important roles in contrast-induced acute kidney injury (CI-AKI). We compared HMGB1 to Hcy as preprocedural predictors for CI-AKI in coronary artery disease (CAD) patients after percutaneous coronary artery intervention (PCI).MethodsWe included 257 eligible patients who were categorized into CI-AKI (  +) and CI-AKI ( −) group. The differences in clinical characteristics and biochemical indexes between two groups were analyzed.ResultsWe observed that thirty-eight (14.8%) of 257 eligible CAD patients developed CI-AKI. HMGB1 (14.6...
Source: International Urology and Nephrology - November 2, 2021 Category: Urology & Nephrology Source Type: research

Sequential Organ Failure Assessment (SOFA) and 90-day mortality in patients with kidney transplant status at first ICU admission: a cohort study of 428 patients
ConclusionThe SOFA scores in the early days of ICU admission were positively associated with 90-day outcomes although the first-day score showed no significant correlation. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - November 2, 2021 Category: Urology & Nephrology Source Type: research

Ankle-brachial index predicts renal outcomes and all-cause mortality in high cardiovascular risk population: a nationwide prospective cohort study in CORE project
ConclusionOur study suggested that PAD independently predicts the incidence of renal progression and all-cause mortality among Thai patients with high CV risk. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - November 1, 2021 Category: Urology & Nephrology Source Type: research

Renoprotective effects of estrogen on acute kidney injury: the role of SIRT1
AbstractAcute kidney injury (AKI) is a common syndrome associated with high morbidity and mortality, despite progress in medical care. Many studies have shown that there are sex differences and different role of sex hormones particularly estrogens in kidney injury. In this regard, the incidence and rate of progression of kidney diseases are higher in men compared with women. These observations suggest that female sex hormone may be renoprotective. Silent information regulator 2 homolog 1 (SIRT1) is a histone deacetylase, which is implicated in multiple biologic processes in several organisms. In the kidneys, SIRT1 inhibits...
Source: International Urology and Nephrology - October 21, 2021 Category: Urology & Nephrology Source Type: research

Serum lactate dehydrogenase level is associated with in-hospital mortality in critically Ill patients with acute kidney injury
AbstractObjectiveSixty percent of critically ill patients suffer from acute kidney injury (AKI) and 12% of them require renal replacement therapy during their ICU stay. However, we lack effective biomarkers to predict the mortality of critically ill patients with AKI. Few studies have investigated the association between lactate dehydrogenase levels and mortality in patients with AKI.MethodsWe conducted a retrospective cohort study with large samples, using a large database, the Multi parameter Intelligent Monitoring in Intensive Care III project. Clinical and demographic data were collected from the database by structure ...
Source: International Urology and Nephrology - October 21, 2021 Category: Urology & Nephrology Source Type: research

Bladder augmentation from an insider ’s perspective: a review of the literature on microcirculatory studies
AbstractAugmentation cystoplasty is an exemplary multiorgan intervention in urology which is particularly associated with microvascular damage. Our aim was to review the available intravital imaging techniques and data obtained from clinical and experimental microcirculatory studies involving the most important donor organs applied in bladder augmentation. Although numerous direct or indirect methods are available to assess the condition of microvessels the implementation of microcirculatory diagnostic methods in humans is still challenging and the assessment of organ microcirculation in the operating theatre has limitatio...
Source: International Urology and Nephrology - October 21, 2021 Category: Urology & Nephrology Source Type: research

Hyperuricemia and hypertriglyceridemia indicate tubular atrophy/interstitial fibrosis in patients with IgA nephropathy and membranous nephropathy
ConclusionsHyperuricemia and hypertriglyceridemia, which were prevalent in CKD patients, were the independent risk factors for moderate  tubular atrophy/interstitial fibrosis. HUA together with HTG could improve the value of diagnosis for moderate tubular atrophy/interstitial fibrosis to some extent. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - October 21, 2021 Category: Urology & Nephrology Source Type: research

LncRNA PVT1 accelerates LPS-induced septic acute kidney injury through targeting miR-17-5p and regulating NF- κB pathway
ConclusionPVT1 knockdown promoted cell viability, suppressed inflammatory response and apoptosis by regulating miR-17-5p expression and NF- κB pathway in LPS-stimulated HK-2 cells. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - October 21, 2021 Category: Urology & Nephrology Source Type: research

Clinicopathological patterns of bladder carcinoma over 1 year: experience from University Hospital of Nepal
ConclusionIn the present study, patients with bladder cancer are younger than reported in other studies. Smokers are strongly predisposed. The histological pattern is similar to the Western and Asian populations. NMIBC and MIBC occur in proportion to that described as in other studies. We had a lower rate of recurrence, upstaging and upgrading. We had a lesser rate of acceptance for radical cystectomy in our patients. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - October 21, 2021 Category: Urology & Nephrology Source Type: research

Urine versus stent cultures and clinical UTIs
ConclusionsSC was a unique risk factor for development of UTI within 12  months of stent removal. Clinicians should consider SC results when empirically treating those with post-operative sepsis or those with UTI afterCandida on SC. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - October 21, 2021 Category: Urology & Nephrology Source Type: research

Management of local recurrence after radical nephrectomy: surgical removal with or without systemic treatment is still the gold standard. Results from a multicenter international cohort
AbstractObjectiveTo evaluate the survival outcomes of patients with local recurrence after radical nephrectomy (RN) and to test the effect of surgery, as monotherapy or in combination with systemic treatment, on cancer-specific mortality (CSM).MethodsPatients with local recurrence after RN were abstracted from an international dataset. The primary outcome was CSM. Cox ’s proportional hazard models tested the main predictors of CSM. Kaplan–Meier method estimates the 3-year survival rates.ResultsOverall, 96 patients were included. Of these, 44 (45.8%) were metastatic at the time of recurrence. The median time to ...
Source: International Urology and Nephrology - October 21, 2021 Category: Urology & Nephrology Source Type: research

Correlation analysis of low-level serum uric acid and cardiovascular events in patients on peritoneal dialysis
AbstractBackgroundThe impact of serum uric acid (SUA) on development of cardiovascular disease (CVD) in patients undergoing peritoneal dialysis (PD) remains controversial, especially the impact of hypouricemia (HUA) on CVD. The aim of our study was to investigate the influence of low-level SUA on cardiovascular (CV) events in PD patients.MethodsA retrospective cohort study was conducted.728 PD patients from February 1, 2010 to May 31, 2019 were enrolled. All demographic and laboratory data were collected at baseline and 6  months after PD treatment. The study cohort was divided into four groups according to SUA level ...
Source: International Urology and Nephrology - October 21, 2021 Category: Urology & Nephrology Source Type: research

Evaluation of pedometer use in men with lower urinary tract symptoms: a randomized clinical trial
ConclusionsThe use of pedometer in LUTS patients provided an increase in the number of steps/day, a decrease in LUTS score and an improvement in VO2max measure.Clinical Trial RegistrationTrial url:www.ensaiosclinicos.gov.br/rg/RBR-4vynk5/. Register Number: RBR-4vynk5 . (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - October 21, 2021 Category: Urology & Nephrology Source Type: research

FRAX scores are increased in patients with ANCA-associated vasculitis
ConclusionAAV patients are at high risk for future fractures as calculated with FRAX. Life-long monitoring for bone disease and fractures are essential. Large studies with longer follow-up are needed to determine the accuracy of FRAX risk scoring in predicting fractures. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - October 21, 2021 Category: Urology & Nephrology Source Type: research

Prognostic performance of clinical assessment tools following hip fracture in patients with chronic kidney disease
ConclusionPatients with advanced CKD and severe frailty have a high mortality risk following hip fracture. The Clinical Frailty Scale is an excellent prognostic tool for mortality in this setting and could be easily incorporated into routine clinical practice. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - October 21, 2021 Category: Urology & Nephrology Source Type: research

Thyroid hormone status in patients with impaired kidney function
AbstractPurposeWe aimed to investigate the prevalence of thyroid hormone abnormalities and the relationship between free triiodothyronine (fT3), thyroid stimulating hormone (TSH) and free thyroxine (fT4) serum levels with kidney function and proteinuria in 4108 subsequent patients admitted to a Nephrology Clinic at a tertiary Medical Centre.MethodsAll patients were categorized based on their estimated glomerular filtration rate (eGFR) as follows: normal —eGFR ≥ 60 ml/min, mild kidney impairment—30 ≤ eGFR 
Source: International Urology and Nephrology - October 21, 2021 Category: Urology & Nephrology Source Type: research

Chronic intermittent self-bladder catheterization with plastic funnel
(Source: International Urology and Nephrology)
Source: International Urology and Nephrology - October 21, 2021 Category: Urology & Nephrology Source Type: research

Letter to the editor re: the effect of  pelvic floor exercise program on incontinence and sexual dysfunction in multiple sclerosis patients Altunan et al., IJUN, (2021) 53:1059
(Source: International Urology and Nephrology)
Source: International Urology and Nephrology - October 21, 2021 Category: Urology & Nephrology Source Type: research

Platelet-to-lymphocyte ratio and prediction of progressive IgA nephropathy: myth or fact?
(Source: International Urology and Nephrology)
Source: International Urology and Nephrology - October 21, 2021 Category: Urology & Nephrology Source Type: research

Bladder augmentation from an insider ’s perspective: a review of the literature on microcirculatory studies
AbstractAugmentation cystoplasty is an exemplary multiorgan intervention in urology which is particularly associated with microvascular damage. Our aim was to review the available intravital imaging techniques and data obtained from clinical and experimental microcirculatory studies involving the most important donor organs applied in bladder augmentation. Although numerous direct or indirect methods are available to assess the condition of microvessels the implementation of microcirculatory diagnostic methods in humans is still challenging and the assessment of organ microcirculation in the operating theatre has limitatio...
Source: International Urology and Nephrology - October 7, 2021 Category: Urology & Nephrology Source Type: research

Urine versus stent cultures and clinical UTIs
ConclusionsSC was a unique risk factor for development of UTI within 12  months of stent removal. Clinicians should consider SC results when empirically treating those with post-operative sepsis or those with UTI afterCandida on SC. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - October 7, 2021 Category: Urology & Nephrology Source Type: research