De novo renal carcinoma arising in non-functional kidney graft: a national retrospective study
ConclusionRenal carcinomas in non-functional grafts are rare entities and most of them are diagnosed fortuitously. Despite the fact that these tumors are small, low grade and with a good prognosis, regular monitoring of non-functional grafts should be performed with at least an annual ultrasonography. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - February 27, 2020 Category: Urology & Nephrology Source Type: research

Microscopic replantation of completely amputated penis and testes: a case report and literature review
ConclusionComplete amputation of the penis and testis is very rare. Efforts should be made to perform the replantation surgery as soon as possible. Microscopic surgical techniques for elaborate vascular and neural anastomosis constitute the basis for a successful replantation. Post-operative comprehensive treatment such as strong anti-infection, analgesia, anti-depression, improvement of microcirculation, and hyperbaric oxygen is crucial for the survival and functional recovery of replanted organs. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - February 25, 2020 Category: Urology & Nephrology Source Type: research

Low diagnostic sensitivity of cystoscopy and cystography of surgically confirmed vesicoenteric fistulae
ConclusionsIn clinical practice, the diagnostic work-up of VEF is variable. In the modern era of managed care, inclusion of cystoscopy and cystography in the evaluation of VEF does not contribute a substantial additive benefit over standard cross-sectional imaging. Cystoscopy and cystography could potentially be eliminated from the diagnostic evaluation of VEF, in the absence of a concern for malignancy, in an effort to minimize unnecessary invasive testing as well as health care expenditures. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - February 25, 2020 Category: Urology & Nephrology Source Type: research

Thirst in patients on chronic hemodialysis: What do we know so far?
AbstractThirst has been defined as “the sensation that leads animal’s and human’s actions toward the goal of finding and drinking water” or as “any drive that can motivate water intake, regardless of cause”. Thirst, together with xerostomia, is the main cause of poor adherence to fluid restriction and of excessive intake of fluids in patients on chronic hemodialysis, and consequently of high interdialytic weight gain. Interdialytic weight gain (IDWG) should be lower than 4.0–4.5% of dry weight. Unfortunately, many patients have an IDWG greater than this value and some have IDWG of ...
Source: International Urology and Nephrology - February 25, 2020 Category: Urology & Nephrology Source Type: research

Brachial –ankle pulse wave velocity is independently associated with urine albumin-to-creatinine ratio in a Chinese community-based cohort
AbstractPurposeArterial stiffness is important in the development of albuminuria. The brachial –ankle pulse wave velocity (baPWV) acts as an indicator of arterial stiffness and may be associated with cardiovascular disease morbidity and mortality. The urine albumin-to-creatinine ratio (UACR) is a metric used to diagnose albuminuria and has also been shown to be associated with cardiovascula r disease. Here, we aim to elucidate the relationship between the baPWV and UACR in the Chinese community.MethodsA community-based cohort of 3669 subjects was selected for the analysis. The BaPWV and UACR were measured from each s...
Source: International Urology and Nephrology - February 25, 2020 Category: Urology & Nephrology Source Type: research

Age-independent secular testosterone populational trends among Brazilian males
ConclusionThe age-independent testosterone decline displays a worrying picture of possibly increasing rates of hypogonadism and its complications in the future. Further studies are needed to fully understand its etiology and impact in populations. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - February 25, 2020 Category: Urology & Nephrology Source Type: research

Bladder cancer: total antioxidant capacity and pharmacotherapy with vitamin-E
ConclusionsBy reference to the significant difference between T-AOC in patients and healthy controls, our results strongly suggest a low level of T-AOC in patients with BC. The obtained changes in T-AOC before and after management with vitamin E recommended additional consideration associates with different stages and grade of tumor in patients with BC. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - February 22, 2020 Category: Urology & Nephrology Source Type: research

Italian real-life clinical setting: the persistence and adherence with mirabegron in women with overactive bladder
ConclusionIn Italy, the cost compromises adherence and persistence of therapy with mirabegron despite the good functional outcomes (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - February 21, 2020 Category: Urology & Nephrology Source Type: research

Comparison of perioperative and oncologic outcomes between robot-assisted and laparoscopic radical cystectomy for bladder cancer: a systematic review and updated meta-analysis
ConclusionsOur findings indicated that patients with RARC may benefit from significantly lower complications, shorter LOS, higher lymph node yield and lower death risk. These data thus showed that RARC might improve the management of patients with muscle invasive or high-risk non-muscle invasive bladder cancer. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - February 20, 2020 Category: Urology & Nephrology Source Type: research

Development and validation of prognostic nomograms in patients with adrenocortical carcinoma: a population-based study
ConclusionWe unveiled the prognostic factors of ACC and developed novel nomograms that predict OS and CSS more accurately and comprehensively, which can help clinicians improve individual treatment, making proper clinical decisions and adjusting follow-up management strategies. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - February 18, 2020 Category: Urology & Nephrology Source Type: research

Penile hemodynamics study in erectile dysfunction men: the influence of smoking obesity on the parameters of penile duplex
ConclusionBoth smoking and BMI are strong risk factors for ED and affect response to ICI and penile duplex parameters (PSV, EDV, RI). Smoking and BMI together cause more deterioration of penile duplex parameters and response to ICI. The effect of smoking on EDV and RI was more than BMI. The effect of BMI on PSV, response to ICI and testosterone levels was more than smoking. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - February 18, 2020 Category: Urology & Nephrology Source Type: research

Meta-analysis and systematic review of intermediate-term follow-up of prostatic urethral lift for benign prostatic hyperplasia
ConclusionPUL is a well-tolerated, minimally invasive therapy for BPH that provides favorable and durable symptomatic, sexual health, and functional outcomes up to 24  months. Longer follow-up and randomized studies comparing to current standards are required to further confirm the long-term sustainability of PUL. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - February 17, 2020 Category: Urology & Nephrology Source Type: research

Do rapid emotional thermometers correlate with multidimensional validated structured questionnaires in low-risk prostate cancer?
ConclusionDT revealed the best correlation to validated structured questionnaires of diverse dimensions with clear potential for quick screening of patients with psychological suffering and in need of further evaluation and support. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - February 13, 2020 Category: Urology & Nephrology Source Type: research

The theoretical method and clinical application of testicular torsion
ConclusionThe reduction of testicular torsion using the elastic retraction method and push-and-turn method may improve the success rate of the manual reduction of testicular torsion, especially for incomplete testicular torsion. Furthermore, manual reduction may help increase the rate of testicular salvage in a timely manner before emergency surgery. Hence, this skill should be extended to primary hospitals to reduce the possibility of testectomy caused by testicular torsion. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - February 12, 2020 Category: Urology & Nephrology Source Type: research

Genistein inhibited the proliferation of kidney cancer cells via CDKN2a hypomethylation: role of abnormal apoptosis
ConclusionsOur results demonstrated that the anti-tumor effect of genistein might induce cell apoptosis and inhibit the proliferation of kidney cancer cells via regulatingCDKN2a methylation. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - February 5, 2020 Category: Urology & Nephrology Source Type: research

Hungry bone syndrome after parathyroidectomy in end-stage renal disease patients: review of an alkaline phosphatase-based treatment protocol
ConclusionImplementation of an ALP-based prophylactic calcium replacement protocol with daily serum calcium monitoring can ameliorate severe hypocalcaemia post-parathyroidectomy (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - February 3, 2020 Category: Urology & Nephrology Source Type: research

Loss of bone mineral density and trabecular bone score in elderly hemodialysis patients: a 2-year follow-up, prospective, single-centre study
ConclusionsIn patients with HDF, significant BMD and TBS annual losses were observed, and they were associated only with age and (in BMD of lumbar spine) with serum calcium and dialysis vintage. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - February 3, 2020 Category: Urology & Nephrology Source Type: research

Endogenous testosterone mirrors prostate cancer aggressiveness: correlation between basal testosterone serum levels and prostate cancer European Urology Association clinical risk classes in a large cohort of Caucasian patients
ConclusionsBasal TT levels are positively associated with low, intermediate and high EAU risk classes. The association is significant for the high-risk class when compared to the low-risk group, but was lost in locally advanced risk class. In PCA patients, high TT serum levels are associated with high-risk disease. Endogenous TT should be considered as a biological marker for assessing EAU PCA risk classes. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - February 3, 2020 Category: Urology & Nephrology Source Type: research

Hypokalemia and hyperkalemia in patients on peritoneal dialysis: incidence and associated factors
ConclusionHyperkalemia and hypokalemia are very frequent in patients on PD and should be closely monitored. Interventional studies should address the impact of discontinuing omeprazole in the levels of potassium. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - February 3, 2020 Category: Urology & Nephrology Source Type: research

Economic burden and cost-utility analysis of three renal replacement therapies in ESRD patients from Yunnan Province, China
AbstractPurposeTo compare the economic burden and cost-utility analysis of the renal replacement therapies, including hemodialysis (HD), peritoneal dialysis (PD), and allograft kidney transplantation (KT) among end-stage renal disease (ESRD) patients from Yunnan Province, China.MethodsMultistage stratified random sampling method was used to select presentative sample of 298 patients from four hospitals in Yunnan Province. The two-step model was applied to calculate a direct economic burden; the human capital approach was used to analyze the indirect economic burden. SF-36 scale was applied to assess the quality of life, wh...
Source: International Urology and Nephrology - February 3, 2020 Category: Urology & Nephrology Source Type: research

Serum albumin changes and mortality risk of peritoneal dialysis patients
AbstractPurposeInitial or single time point serum albumin levels have been shown to be important in predicting the prognosis of peritoneal dialysis (PD) patients. However, we assume the dynamic change and trend of albumin after PD are essential. We aimed to investigate the association between baseline albumin levels, albumin trajectories, and patient mortality in a retrospective cohort study.MethodsIn this retrospective cohort study, 547 incident PD patients were enrolled from Peking University Third Hospital. Date were collected by medical records review, including age, gender, body mass index, primary disease, comorbidit...
Source: International Urology and Nephrology - February 3, 2020 Category: Urology & Nephrology Source Type: research

Silencing CCNG1 protects MPC-5 cells from high glucose-induced proliferation-inhibition and apoptosis-promotion via MDM2/p53 signaling pathway
ConclusionsThese findings revealed that down-regulation of CCNG1 has protection effects in DN that is mechanistically linked to MDM2-p53 pathways. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - February 3, 2020 Category: Urology & Nephrology Source Type: research

Sodium and urea excretion as determinants of urine output in autosomal dominant polycystic kidney disease patients on V2 receptor antagonists: impact of dietary intervention
AbstractPurposeTolvaptan, a vasopressin V2 receptor antagonist, slows the decline in renal function in autosomal dominant polycystic kidney disease (ADPKD). However, it increases urine output such that patient adherence could be compromised. In a cohort of patients with ADPKD on tolvaptan, we aimed to identify the contribution of sodium and urea excretion rate to daily urine output, and to evaluate the effectiveness of dietary counseling on sodium and urea excretion rates.MethodsRetrospective analysis of 30 ADPKD patients who underwent a single session of personalized dietary counseling to reduce sodium and protein intake ...
Source: International Urology and Nephrology - February 1, 2020 Category: Urology & Nephrology Source Type: research

Eco-dialysis: fashion or necessity
AbstractHemodialysis (HD) is one of the resource hungry medical interventions. A huge volume of water (about 500  L) and significant amounts of energy (over 7 kW) are used for a hemodialysis session; over a kilogram of waste is produced during this procedure. Thus, HD contributes to global warming while saving patients’ lives. In this paper, we showed these crucial points in HD treatment and possible ways (e.g. modifications in dialysate flow rate) to reduce environmental impact maintaining therapy standards. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - February 1, 2020 Category: Urology & Nephrology Source Type: research

Kidney function predicts the risk of asymptomatic peripheral arterial disease in a Chinese community-based population
AbstractPurposeLower-extremity peripheral arterial disease (PAD) can predict the risk of subsequent cardiovascular disease (CVD) and all-cause mortality. Chronic kidney disease (CKD) as a precursor of CVD has been proven to be independently associated with PAD. However, few data exist regarding the prediction value of kidney function for incident asymptomatic PAD in community-based populations. We aimed to investigate the predicting value of estimated glomerular filtration rate (eGFR) for incident asymptomatic PAD in a Chinese community-based population. A total of 3549 subjects without PAD and eGFR  >  30...
Source: International Urology and Nephrology - February 1, 2020 Category: Urology & Nephrology Source Type: research

High-sensitivity Troponin I Predicts Galectin-3 in Chronic Kidney Disease Patients
AbstractPurposePlasma galectin-3 (pG3) regulates inflammation. B-type natriuretic peptide (BNP), high-sensitivity Troponin I (hsTnI), and pG3 concentrations are elevated in chronic kidney disease (CKD) patients. The associations of pG3 with hsTnI/BNP are unclear. We explored the relationship of hsTnI and BNP with pG3 in Asian CKD patients and healthy controls.MethodsWe retrieved prospectively collected frozen plasma samples from 163 stable CKD patients and 105 healthy controls. BNP, hsTnI and pG3 were assayed. pG3 was assessed for associations with age, gender, ethnicity, blood pressures; height, weight, body mass index (B...
Source: International Urology and Nephrology - February 1, 2020 Category: Urology & Nephrology Source Type: research

Differential diagnosis of calciphylaxis in chronic dialysis patients
(Source: International Urology and Nephrology)
Source: International Urology and Nephrology - February 1, 2020 Category: Urology & Nephrology Source Type: research

Serum osmolarity as a potential predictor for contrast-induced nephropathy following elective coronary angiography
AbstractBackground and objectivesContrast-induced nephropathy (CIN) is a relatively common complication following primary coronary angiography (CAG) or percutaneous coronary intervention (PCI), especially in at-risk patients. The goal of this study is to evaluate the role of pre-procedural serum osmolarity as a risk factor for CIN in patients undergoing elective CAG for stable coronary artery disease (CAD).Materials and methodsA total of 356 stable CAD patients scheduled to undergo CAG or PCI were included in this two-center study. Serum osmolarity was calculated on admission. CIN was defined according to the KDIGO criteri...
Source: International Urology and Nephrology - February 1, 2020 Category: Urology & Nephrology Source Type: research

Resistant starch supplementation attenuates inflammation in hemodialysis patients: a pilot study
AbstractPurposeIn chronic kidney disease (CKD) patients, dysbiosis is associated with inflammation and cardiovascular risk, so many nutritional strategies are being studied to reduce these complications. Resistant starch (RS) can be considered a prebiotic that promotes many benefits, including modulation of gut microbiota which is linked to immune-modulatory effects. The aim of this study was to evaluate the effects of RS supplementation on proinflammatory cytokines in CKD patients on hemodialysis (HD).MethodsA double-blind, placebo-controlled, randomized trial was conducted with sixteen HD patients (55.3  ±&...
Source: International Urology and Nephrology - February 1, 2020 Category: Urology & Nephrology Source Type: research

Volumetric evaluation of renal sinus adipose tissue on computed tomography images in bilateral nephrolithiasis patients
AbstractPurposeTo compare renal sinus fat volume (RSFV) separately within the right and left kidneys between bilateral nephrolithiasis patients and healthy controls.MethodsThis cross-sectional study analyzed patients who underwent unenhanced abdominal computed tomography (CT) divided into nephrolithiasis (n = 102) and healthy control (n = 130) groups. Age, sex, blood pressure [systolic blood pressure (SBP) and diastolic blood pressure (DBP)], estimated glomerular filtration rate (eGFR), body weight, and height of each participant were extracted. Volumetric renal sinus adipose tissue was measured...
Source: International Urology and Nephrology - January 31, 2020 Category: Urology & Nephrology Source Type: research

Risk calculator for prediction of treatment-related urethroplasty failure in patients with penile urethral strictures
ConclusionsLong-term prognosis in patients who underwent penile urethroplasty is uncertain. To date, our risk-calculator represents the first tool that might help physicians to predict the risk of treatment failure at 10  years. According to our model, such risk is largely influenced by the etiology of the stricture, the use of graft, and patient’s smoking habits. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - January 30, 2020 Category: Urology & Nephrology Source Type: research

Gender effect on the oncologic outcomes of upper urinary tract urothelial carcinoma in Taiwan
ConclusionCompared with female UTUC patients, male UTUC patients in Taiwan were associated with more bladder recurrences and higher cancer-specific mortality and had a trend associated with more systemic recurrences. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - January 29, 2020 Category: Urology & Nephrology Source Type: research

Effect of surgical repair of acquired buried penis on sexual function in adults
This study was performed to investigate the effect of surgical repair of acquired buried penis on sexual function in adults and provide a reference for clinical treatment.MethodsThirty-two adult patients who underwent surgical treatment of buried penis from August 2010 to August 2017 were selected as the study group. The basic operative method was penile lengthening. Suprapubic liposuction, suspensory ligament release, and preputial plasty were performed according to the clinical manifestations. The changes in erectile function, orgasmic function, sexual desire, intercourse satisfaction, and overall satisfaction sexual fun...
Source: International Urology and Nephrology - January 28, 2020 Category: Urology & Nephrology Source Type: research

Worsening disability status in multiple sclerosis predicts urologic complications
AbstractPurposeMultiple sclerosis (MS) causes voiding dysfunction and might predispose to urologic complications. However, long-term complications and risk factors for complications are unknown. We aim to assess long-term changes in voiding function and to determine risk factors for urologic complications during MS follow-up.MethodsWe analyzed the records of MS patients and recorded baseline and follow-up voiding symptoms, urodynamic (UDS) findings, Expanded Disability Status Scale (EDSS), serum blood studies, imaging, and complications.T test and Chi-square test were used to determine statistical significance using a two-tailedp value
Source: International Urology and Nephrology - January 25, 2020 Category: Urology & Nephrology Source Type: research

Long-term evaluation of modified orthotopic Y-shaped ileal neobladder (Tanta pouch) with left retro-colic chimney
ConclusionModified Y-shaper pouch is suitable for short, dilated ureters. Longitudinal orientation of the pouch facilitates ileo-urethral anastomosis, especially with short mesentery. Long-term follow-up for direct uretero-ileal anastomosis did not show deterioration of the renal function. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - January 24, 2020 Category: Urology & Nephrology Source Type: research

Frailty and mortality among patients with chronic kidney disease and end-stage renal disease: a systematic review and meta-analysis
AbstractPurposeFrailty is highly prevalent among patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD). Previous studies have shown that frailty is a sensitive predictor of survival in the elderly. However, convincing evidence supporting the causality between frailty and the adverse outcome in CKD patients is still lacking.MethodsPubMed, Embase, MEDLINE and the Cochrane Central Register of Controlled Trials (CENTRAL) databases were searched for identifying potentially relevant literature. Studies that investigated the association between frailty and overall mortality in patients with CKD and ESRD we...
Source: International Urology and Nephrology - January 18, 2020 Category: Urology & Nephrology Source Type: research

Selected cardiovascular risk factors in early stages of chronic kidney disease
AbstractCardiovascular diseases, including hypertension, congestive heart failure, myocardial infarction, stroke and atherosclerosis, are common in patients with chronic kidney disease. Aside from the standard biomarkers, measured to determine cardiovascular risk, new ones have emerged: markers of oxidative stress, apoptosis, inflammation, vascular endothelium dysfunction, atherosclerosis, organ calcification and fibrosis. Unfortunately, their utility for routine clinical application remains to be elucidated. A causal relationship between new markers and cardiovascular diseases in patients with chronic kidney disease remai...
Source: International Urology and Nephrology - January 18, 2020 Category: Urology & Nephrology Source Type: research

Evaluation of dynamic thiol-disulphide homeostasis in obstructive uropathy
ConclusionsAssociation with scintigraphic and pathological results empowers the value of this parameter. Disulphide/native thiol and native thiol/total thiol ratios indicate complete obstruction. These findings may shed light to more comprehensive studies. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - January 18, 2020 Category: Urology & Nephrology Source Type: research

Dialysis-associated hyperglycemia: manifestations and treatment
ConclusionsIn DAH, insulin infusion is the primary management strategy and corrects the fluid and electrolyte abnormalities. Patients treated for DAH should be monitored for the development of hypoglycemia or fluid and electrolyte abnormalities that may require additional treatments. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - January 18, 2020 Category: Urology & Nephrology Source Type: research

The role of hypertriglyceridemia and treatment patterns in the progression of IgA nephropathy with a high proportion of global glomerulosclerosis
ConclusionsA high proportion of global glomerulosclerosis combined with HTG at biopsy have better predictive validity for the disease progression of IgAN than global glomerulosclerosis alone. TwHF may partially affect the renal outcome of severe IgAN with HTG, and this may relate to its regulation of lipid metabolism and immunoinflammatory response. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - January 18, 2020 Category: Urology & Nephrology Source Type: research

Mean platelet volume-to-lymphocyte ratio: a novel biomarker associated with overall survival in patients with nonmetastatic clear cell renal cell carcinoma treated with nephrectomy
ConclusionMPVLR is an easily obtainable prognostic marker for overall survival in nonmetastatic ccRCC patients treated with nephrectomy. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - January 17, 2020 Category: Urology & Nephrology Source Type: research

A pilot study of autologous rectus fascial wrap at the time of artificial urinary sphincter placement in patients at risk of cuff erosion
ConclusionThe autologous fascial wrap technique is efficient and easy to harvest, with comparable clinical outcomes to other techniques. The medium-term results have been encouraging, but longer-term follow up is needed. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - January 17, 2020 Category: Urology & Nephrology Source Type: research

Kidney transplantation improves arterial stiffness in patients with end-stage renal disease
ConclusionsAortic stiffness could be improved after KT. Meanwhile, age, BMI, systolic blood pressure, pulse pressure, length of KT and BUN were independent predictors of the increase of CF-PWV in KTRs. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - January 10, 2020 Category: Urology & Nephrology Source Type: research

Post ureteroscopic stone surgery ureteral strictures management: a retrospective study
AbstractPurposeTo share experience in managing ureteral strictures following ureteroscopic lithotripsy.MethodsNinety five patients diagnosed as ureteral strictures after ureteroscopic lithotripsy between January 2013 and January 2018 were included. 53 received endourological treatment, 34 underwent reconstruction, 6 underwent nephrectomy for severe renal impairment, and 2 chose routine ureteral stent replacement. Therapeutic success was defined as absence of clinical symptoms and radiologic relief of obstruction.ResultsThe follow-up time ranged from 13 to 57  months, with a median time of 24. It lasted more than 13&nb...
Source: International Urology and Nephrology - January 10, 2020 Category: Urology & Nephrology Source Type: research

Castration-resistant prostate cancer without metastasis at presentation may achieve cancer-specific survival in patients who underwent prior radical prostatectomy
ConclusionsCRPC is one of the lethal causes with PCa death. However, nmCRPC may achieve relatively good prognosis in patients with PCa after RP. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - January 3, 2020 Category: Urology & Nephrology Source Type: research

The role of intravesical prostatic protrusion in the evaluation of overactive bladder in male patients with LUTS
ConclusionIPP is not a good predictor of OAB in men presenting with LUTS. However, grade 3 IPP indicates higher frequency of nocturia. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - January 2, 2020 Category: Urology & Nephrology Source Type: research

The prevalence of frailty in patients on hemodialysis: a systematic review and meta-analysis
ConclusionsFrailty influences almost three in ten patients on hemodialysis. Understanding the underlying pathophysiology mechanisms and weakening the impacts of frailty in patients on hemodialysis are called on to action in the future work. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - January 1, 2020 Category: Urology & Nephrology Source Type: research

Cardio-ankle vascular index is linked to deranged metabolic status, especially high HbA1c and monocyte-chemoattractant-1 protein, in predialysis chronic kidney disease
AbstractIntroduction and purposeArterial stiffness is an independent predictor of cardiovascular disease in chronic kidney disease (CKD). Cardio-ankle vascular index (CAVI) is a newly developed method used to assess arterial stiffness, independent of changes in blood pressure. CAVI reflects stiffness and atherosclerosis at the thoracic, abdominal, common iliac, femoral, and tibial artery levels. In predialysis stage 3 –5 diabetic and nondiabetic CKD patients, CAVI levels and its relation to atherosclerosis-associated risk factors including monocyte-chemoattractant protein-1 (MCP-1), sclerostin, fibroblast growth fact...
Source: International Urology and Nephrology - January 1, 2020 Category: Urology & Nephrology Source Type: research

Serum levels of the endothelial glycocalyx constituents and the early failure of forearm autologous arteriovenous fistulas in end-stage renal disease patients: a prospective cohort study
AbstractBackgroundThe relationship between the endothelial glycocalyx constituents and the early failure of autologous arteriovenous fistulas (AVFs) in ESRD patients is still unknown.MethodsIn this prospective cohort study, 181 ESRD patients (the mean age was 53.3  ± 11.8 years, 66.3% of them were males) received forearm AVFs surgery were consecutively enrolled with a median follow-up time of 10 months. The early AVF failure was defined as a fistula that never developed adequately for dialysis use or that failed within the first 3 months of use. The s erum levels of glycocalyx constituen...
Source: International Urology and Nephrology - January 1, 2020 Category: Urology & Nephrology Source Type: research

Comparison of the effects of valsartan plus activated vitamin D versus valsartan alone in IgA nephropathy with moderate proteinuria
AbstractBackground/aimsTo compare the effects of valsartan plus activated vitamin D with valsartan alone on urinary protein excretion and eGFR in IgA nephropathy with moderate proteinuria.MethodsA prospective, single-center, randomized, controlled study was performed between Jan, 2008 and Jan, 2018 on patients with IgA nephropathy who had moderate proteinuria with urinary protein excretion 1.0 –3.0 g/24 h. These IgAN patients were randomly assigned to receive either valsartan 160 mg/day treatment or valsartan 160 mg/day plus activated vitamin D (calcitriol) 0.5 μg/day treatments. The chang...
Source: International Urology and Nephrology - January 1, 2020 Category: Urology & Nephrology Source Type: research