International Urology and Nephrology 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.A protective role of nintedanib in peritoneal fibrosis through H19 –EZH2–KLF2 axis via impeding mesothelial-to-mesenchymal transition
ConclusionIn summary, nintedanib disrupts MMT process through regulating H19/EZH2/KLF2 axis and TGF- β/Smad pathway, which laid the experimental foundation for nintedanib in the treatment of PF. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - December 14, 2023 Category: Urology & Nephrology Source Type: research
Comparison of morbidity and mortality after radical cystectomy between individuals older and younger than 80 years: a systematic review and meta-analysis
ConclusionIndividuals older than 80 years undergoing RC are likely to have poor survival-related outcomes and increased complications risks. Pre-planned comprehensive geriatric assessments (CGAs) may be needed to offer better peri- and post-operative care to improve the outcomes in this patient population. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - December 14, 2023 Category: Urology & Nephrology Source Type: research
Evaluation of arteriovenous fistula for hemodialysis with a new generation digital stethoscope: a pilot study
ConclusionsThe analysis of sound waves by a digital stethoscope permitted us to distinguish between stenotic and no stenotic AVFs. The standardization of this technique and the introducing of data in a deep learning algorithm could allow an objective and fast method for a frequent monitoring of AVF. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - December 13, 2023 Category: Urology & Nephrology Source Type: research
Mesial temporal atrophy in preoperative MRI rather than steep Trendelenburg position is associated with postoperative delirium in patients undergoing a major urologic surgery
ConclusionSteep Trendelenburg was not associated with postoperative delirium. Significant mesial temporal atrophy (Scheltens ’ scale ≥ 2) in preoperative brain MRI was predictive of postoperative delirium.Trial registrationNot applicable. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - December 13, 2023 Category: Urology & Nephrology Source Type: research
Characterization of gut microbiota in patients with stage 3 –4 chronic kidney disease: a retrospective cohort study
ConclusionsIn conclusion, our study underscores the profound influence of gut microbiota dysbiosis on CKD progression. The distinct microbial profiles observed in CKD patients highlight the potential efficacy of microbiota-based interventions in mitigating CKD advancement. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - December 12, 2023 Category: Urology & Nephrology Source Type: research
Natural history of renal angiomyolipoma in a high-volume center: our experience during more than 15 years of follow up
ConclusionsThe findings of this study suggest that AML typically demonstrate a slow-progressing clinical course during long-term follow-up. Moreover, our observations, which cast doubt on tumor size as a reliable predictor of adverse clinical outcomes, advocate for a less intensive monitoring strategy in both monitoring frequency and choice of imaging modality. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - December 12, 2023 Category: Urology & Nephrology Source Type: research
A legacy of excellence: celebrating 40 years of the Diokno–Lapides essay contest
AbstractThe Diokno –Lapides Essay Contest was originally established in 1984 as the Jack Lapides Essay Contest on Urodynamic and Neurourology Research. Developed by Ananias Diokno to honor his mentor, Jack Lapides at the University of Michigan, it was funded by a grant from Marion Laboratories. The contest recognize s individuals doing outstanding work in neurourology and has been awarded yearly since 1985. Renamed the Diokno–Lapides Essay Contest in 2014, it has generated significant papers and discoveries in neurourology. Spanning 40 years, winners and other participants have attested to the contest’s in fluence o...
Source: International Urology and Nephrology - December 11, 2023 Category: Urology & Nephrology Source Type: research
Higher dietary acid load is associated with the risk of hyperuricemia
ConclusionThis study showed a significant positive association between two indicators of dietary acid load (PRAL, and DAL) and odds of hyperuricemia among Iranian adults. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - December 10, 2023 Category: Urology & Nephrology Source Type: research
Investigation of intradetrusor onabotulinum toxin A efficacy and safety in older adults with urge urinary incontinence
ConclusionThis real-world study demonstrates that BTX-A effectively controls OAB symptoms in elderly women, with just two injections annually. BTX-A appears safe and efficacious for treating OAB in elderly females. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - December 10, 2023 Category: Urology & Nephrology Source Type: research
Association between the cardiometabolic index and chronic kidney disease: a cross-sectional study
ConclusionsHigher CMI was independently associated with higher CKD risk in the general population. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - December 8, 2023 Category: Urology & Nephrology Source Type: research
Effect of exercise training on functional capacity, muscle strength, exercise capacity, dialysis efficacy and quality of life in children and adolescents with chronic kidney disease: a systematic review and meta-analysis
ConclusionExercise training could benefit children and adolescents with CKD by increasing their strength. Longer exercise interventions may be beneficial for improving functional capacity and QOL. Future well-designed RCTs should overcome the existing limitations using adequate sample sizes and longer exercise durations. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - December 6, 2023 Category: Urology & Nephrology Source Type: research
Advantages of retrograde intrarenal incision versus laparoscopic surgery in management of pararenal cysts: a single-center experience
ConclusionsRIRS demonstrated several advantages over laparoscopic surgery for the internal incision of parapelvic cysts, including shorter operative duration, shorter hospital stay, and less postoperative pain control. These findings may guide the selection of appropriate surgical approaches for patients with renal cysts. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - December 3, 2023 Category: Urology & Nephrology Source Type: research
Evaluation of the efficacy and safety of either or both mirabegron and silodosin, as a medical expulsive therapy for distal ureteric stones
ConclusionsThe findings of this study suggest that both silodosin and mirabegron are effective treatments for the expulsion of lower ureteric stones. Furthermore, the combination of these medications leads to an increased rate of stone expulsion and a reduced duration of expulsion. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - December 2, 2023 Category: Urology & Nephrology Source Type: research
Shuangshi Tonglin Capsule treats benign prostatic hyperplasia through the ROS/NLRP3 signaling pathway
ConclusionSSTL can reduce the PI and RI in BPH rats, it can also inhibit the level of sex hormones and inflammatory factors in BPH rats, which thereby reducing the histopathological damage of prostate gland in BPH rats, and can treat BPH in rats through ROS/NLRP3 pathway. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - December 1, 2023 Category: Urology & Nephrology Source Type: research
The effects of radiation on myeloid lineage immune cells within the rodent urinary bladder: a systematic review
ConclusionAlthough the studies reviewed provide some insight into the role of these immune cells in disease pathology, the limited number of studies and unclear risk of bias further highlights a need for additional, high-quality research in this area. In summary, this systematic review highlights a need to understand the involvement of immune cells in radiation-induced cystitis pathophysiology and lay the groundwork for further research in this area.Trial registrationPROSPERO registration: CRD42022345960 (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - October 27, 2023 Category: Urology & Nephrology Source Type: research
