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Association between controlling nutritional status score and chronic kidney disease in diabetic patients: a cross-sectional study based on the National Health and Nutrition Examination Survey
ConclusionsMalnutrition was associated with the high odds of CKD in T2DM patients, indicating that actively monitoring the nutritional status is important for the management of CKD in T2DM patients. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - January 25, 2024 Category: Urology & Nephrology Source Type: research

Role of metabolomic profile as a potential marker to discriminate membranous nephropathy from IgA nephropathy
ConclusionsSubstantial metabolic disorders occurred during the progression of MN and IgAN. L-tryptophan, L-kynurenine, GABA, indoleacetaldehyde, 5-hydroxyindoleacetylglycine, and N-alpha-acetyllysine may show potential as biomarkers for the identification of MN and IgAN. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - January 25, 2024 Category: Urology & Nephrology Source Type: research

Clear cell renal cell carcinoma cells show diffuse expression of phagocytotic markers through the identification of lysosome-rich eosinophilic granules
ConclusionsThe eosinophilic granules in clear cell RCC are expanded lysosomes, and this may be used as a unique feature for confirming the pathologic diagnosis of clear cell RCC. The findings further support the view that clear cell RCC have phagocytic capacity due to their containing abundant lysosomes in the cytoplasm. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - January 25, 2024 Category: Urology & Nephrology Source Type: research

Efficacy of low-intensity shockwave therapy with different tadalafil regimens in patients with PDE5 inhibitor-resistant erectile dysfunction: a retrospective cohort study
In this study, a cohort of 105 patients with PDE5i-resistant ED was recruited and divided into three groups labeled as A (only LI-SWT), B (LI-SWT plus 5  mg tadalafil daily), and C (LI-SWT plus 20 mg tadalafil alternate-day), comprising 27, 42, and 36 patients, respectively. The patients' International Index of Erectile Function-5 (IIEF-5) scores and the Erection Hardness Score (EHS) were evaluated at the baseline, three months and six months foll owing the treatment.ResultsAfter three months post-treatment, the IIEF-5 scores in group A, B, and C increased by 4.1  ± 0.6, 7.3 ± 0.6, and 8.2 ± 0.6, respectiv...
Source: International Urology and Nephrology - January 25, 2024 Category: Urology & Nephrology Source Type: research

Secondary tumours in orthotopic neobladder using isolated gut segment post radical cystectomy for urothelial carcinoma: a systematic review
ConclusionThe nature of recurrence is hypothesised to be due to seeding of urothelial cells into the non-urothelial surfaces compatible for both implantation and growth. We present the first systematic review to report on recurrence rates and details of diagnosis and outcomes of various management regimes for urothelial carcinoma of the neobladder. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - January 25, 2024 Category: Urology & Nephrology Source Type: research

Randomized trial to assess the potential role of ascorbic acid and statin for post-contrast acute kidney injury prevention
ConclusionsStatin and ascorbic acid did not statistically improve neither serum creatinine nor eGFR values in patient underwent CECT. However, it can decrease the incidence of the clinically insignificant PC-AKI. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - January 25, 2024 Category: Urology & Nephrology Source Type: research

Failed insertion of ureteral access sheath during flexible ureterorenoscopy: a randomized controlled trial comparing second session flexible ureterorenoscopy or same session mini percutaneous nephrolithotomy
ConclusionsPerforming mPNL in the same session, results in better improvements in SF-36 parameters such as pain and physical function compared to f-URS. The success and complication rates of the two procedures were comparable. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - January 25, 2024 Category: Urology & Nephrology Source Type: research

Renal, cardiovascular, and safety outcomes of adding sodium –glucose cotransporter-2 inhibitors to insulin therapy in patients with type-2 diabetes: a meta-analysis
ConclusionAdding SGLT2is to insulin therapy in T2DM patients showed better glucose control and decreased albuminuria, uric acid, blood pressure, and body weight without a reduction in the eGFR. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - January 25, 2024 Category: Urology & Nephrology Source Type: research

Regulator of G protein signaling-1 regulates immune infiltration and macrophage polarization in clear cell renal cell carcinoma
ConclusionsRGS1 is highly expressed in ccRCC, while overexpression of RGS1 may increase immune infiltration in the TME and reduce the polarization of M2 macrophages while promoting apoptosis in ccRCC. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - January 25, 2024 Category: Urology & Nephrology Source Type: research

Association of statin use after renal replacement therapy with mortality in patients with dialysis-requiring acute kidney injury
ConclusionFor patients with dialysis-requiring acute kidney injury, statin therapy during hospitalization period after renal replacement therapy was associated with decreased 1-year mortality and in-hospital mortality. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - January 25, 2024 Category: Urology & Nephrology Source Type: research

Laparoscopic assisted dismembered pyeloplasty versus open pyeloplasty in UPJO with poorly function kidney in pediatrics
ConclusionLaparoscopic assisted pyeloplasty is an effective treatment for patients with poorly functioning kidneys, especially those with less than 10% function. While this surgical procedure requires shorter operative times, it yields functional outcomes that are comparable to open approach. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - January 25, 2024 Category: Urology & Nephrology Source Type: research

Development and validation of the patient-reported outcome scale for chronic kidney disease
ConclusionThe CKD-PROs scale has great reliability, validity, reactivity, acceptability and is capable of being used as one of the evaluation tools for the clinical outcomes of CKD patients. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - January 25, 2024 Category: Urology & Nephrology Source Type: research

Association of dietary carotenoid intake with the prevalence kidney stones among the general adult population
ConclusionOur findings indicated that higher dietary carotenoid intake levels were associated with decreased prevalence of kidney stones, and increasing the intake of foods rich in β-carotene may prevent the development of kidney stones. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - January 25, 2024 Category: Urology & Nephrology Source Type: research

Ureteropelvic junction obstruction with polyps in children: clinical manifestations and supranormal preoperative differential renal function
ConclusionThe preoperative renal function of UPJO patients with polyps was well preserved, and 38.89% of them had supranormal pre-DRF. Patients with supranormal pre-DRF can be managed with the same strategies as those with normal renal function. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - January 25, 2024 Category: Urology & Nephrology Source Type: research

The first experience with the use of dapagliflozin in combination with ACEi for treatment of IgA nephropathy after kidney transplantation
(Source: International Urology and Nephrology)
Source: International Urology and Nephrology - January 25, 2024 Category: Urology & Nephrology Source Type: research