The indirect costs of human papillomavirus-related cancer in Central and Eastern Europe: years of life lost and productivity costs
CONCLUSIONS: There is a high disease burden of HPV-related cancer-related deaths in the CEE region, with a large economic impact to society due to substantial productivity losses. It is critical to implement and reinforce public health measures with the aim to reduce the incidence of HPV-related diseases, and the subsequent premature cancer deaths. Improving HPV screening and increasing vaccination programs, in both male and female populations, could help reduce this burden.PMID:38638098 | DOI:10.1080/13696998.2024.2341572 (Source: Journal of Medical Economics)
Source: Journal of Medical Economics - April 19, 2024 Category: Health Management Authors: Ugne Sabale Eugenia Karamousouli Lazar Popovic Zo árd Tibor Krasznai Daniel Harrop Anne Meiwald Robert Hughes Georgie Weston Goran Bencina Source Type: research
Temporal characterization of acute pain and toxicity kinetics during radiation therapy for head and neck cancer. A retrospective study
CONCLUSION: This study provides insight on in-depth characterization and associations between dynamic pain, physiologic, and toxicity kinetics. Our findings support further needs of optimized pain control through temporal data-driven clinical decision support systems for acute pain management.PMID:38638130 | PMC:PMC11025722 | DOI:10.1016/j.oor.2023.100092 (Source: Pain Physician)
Source: Pain Physician - April 19, 2024 Category: Anesthesiology Authors: Vivian Salama Sara Youssef Tianlin Xu Kareem A Wahid Jaime Chen Jillian Rigert Anna Lee Katherine A Hutcheson Brandon Gunn Jack Phan Adam S Garden Steven J Frank William Morrison Jay P Reddy Michael T Spiotto Mohamed A Naser Cem Dede Renjie He Abdallah S Source Type: research
Temporal characterization of acute pain and toxicity kinetics during radiation therapy for head and neck cancer. A retrospective study
CONCLUSION: This study provides insight on in-depth characterization and associations between dynamic pain, physiologic, and toxicity kinetics. Our findings support further needs of optimized pain control through temporal data-driven clinical decision support systems for acute pain management.PMID:38638130 | PMC:PMC11025722 | DOI:10.1016/j.oor.2023.100092 (Source: Pain Physician)
Source: Pain Physician - April 19, 2024 Category: Anesthesiology Authors: Vivian Salama Sara Youssef Tianlin Xu Kareem A Wahid Jaime Chen Jillian Rigert Anna Lee Katherine A Hutcheson Brandon Gunn Jack Phan Adam S Garden Steven J Frank William Morrison Jay P Reddy Michael T Spiotto Mohamed A Naser Cem Dede Renjie He Abdallah S Source Type: research
The indirect costs of human papillomavirus-related cancer in Central and Eastern Europe: years of life lost and productivity costs
CONCLUSIONS: There is a high disease burden of HPV-related cancer-related deaths in the CEE region, with a large economic impact to society due to substantial productivity losses. It is critical to implement and reinforce public health measures with the aim to reduce the incidence of HPV-related diseases, and the subsequent premature cancer deaths. Improving HPV screening and increasing vaccination programs, in both male and female populations, could help reduce this burden.PMID:38638098 | DOI:10.1080/13696998.2024.2341572 (Source: Journal of Medical Economics)
Source: Journal of Medical Economics - April 19, 2024 Category: Health Management Authors: Ugne Sabale Eugenia Karamousouli Lazar Popovic Zo árd Tibor Krasznai Daniel Harrop Anne Meiwald Robert Hughes Georgie Weston Goran Bencina Source Type: research
Neoadjuvant chemoimmunotherapy shows major pathological response and low recurrence in head and neck squamous cell carcinoma
ConclusionNeoadjuvant chemoimmunotherapy of HNSCC showed high rate of pathological response and low recurrence rate, holding promise for becoming the new standard of care for resectable HNSCC. (Source: Clinical and Translational Oncology)
Source: Clinical and Translational Oncology - April 19, 2024 Category: Cancer & Oncology Source Type: research
Cancers, Vol. 16, Pages 1575: The Role of Estrogen and Estrogen Receptors in Head and Neck Tumors
etić
Head and neck squamous cell carcinoma (HNSCC) is the most common histological form of head and neck tumors (HNTs), which originate from the epithelium of the lips and oral cavity, pharynx, larynx, salivary glands, nasal cavity, and sinuses. The main risk factors include consumption of tobacco in all forms and alcohol, as well as infections with high-risk human papillomaviruses or the Epstein–Barr virus. Regardless of the etiological agent, the risk of developing different types of HNTs is from two to more than six times higher in males than in females. The reason for such disparities probably lies i...
Source: Cancers - April 19, 2024 Category: Cancer & Oncology Authors: Kranj čević Čonkaš Ozreti ć Tags: Review Source Type: research
Re-irradiation versus systemic therapy for the management of local-regionally recurrent head and neck cancer
CONCLUSION: Although re-irradiation improved overall survival compared to systemic therapy for appropriately selected patients with local-regionally recurrent head and neck cancer, the relatively high risk of toxicity must be considered.PMID:38636710 | DOI:10.1016/j.radonc.2024.110278 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 18, 2024 Category: Radiology Authors: Allen M Chen Jeremy P Harris Rupali Nabar Tjoson Tjoa Yarah Haidar William B Armstrong Source Type: research
Cancers, Vol. 16, Pages 1550: Precursor Lesions, Overdiagnosis, and Oral Cancer: A Critical Review
o
Despite the profession placing great emphasis on oral potentially malignant disorders (OPMDs) as a gateway for early recognition and consequently better outcomes for oral cancer, the death rates for lip and oral cavity cancer have remained stagnant for three decades. Evidence shows that only a small fraction of oral cancers are in fact preceded by OPMDs, and that most OPMDs have an annual transformation rate of less than 1%. As OPMDs encompass a very heterogeneous group of oral conditions, it could be argued that only patients with oral mucosal diseases bearing a substantial risk of malignant transformation warrant c...
Source: Cancers - April 18, 2024 Category: Cancer & Oncology Authors: Nicola Cirillo Tags: Review Source Type: research
The incidence of osteoradionecrosis of the jaws in oral cavity cancer patients treated with intensity-modulated radiotherapy: A systematic review and meta-analysis
A systematic review with meta-analysis was conducted to define the incidence of osteoradionecrosis (ORN) in patients with oral cavity cancer (OCC) treated with intensity-modulated radiotherapy (IMRT), and to identify the risk factors influencing its development. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - April 18, 2024 Category: ENT & OMF Authors: Luis Augusto de Almeida-Silva, Juliana dos Santos Lupp, Leonardo Alvares Sobral-Silva, Luiz Augusto Rodrigues dos Santos, Thays Oliveira Marques, Danillo Babinskas Ribeiro da Silva, Taciana Marco Ferraz Caneppele, Michelle Bianchi-de-Moraes Source Type: research
Role of Imaging in Predicting the Deep Surgical Margin in Gingivobuccal Complex Cancers: A Pilot Study
AbstractCancers arising from the gingivobuccal complex are one of the most common types of cancer in the oral cavity and are associated with poor prognosis. Among the various prognostic factors, positive surgical margin is the most important one that can be controlled by the operating surgeon. The deep surgical margins for buccal mucosa cancers is normally assessed by palpating the skin for induration and skin pinchability. The present study evaluates the role of imaging in assessing the deep surgical margin and its efficacy for skin preservation in buccal mucosa/ gingivobuccal carcinomas. The patients of gingivobuccal com...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - April 18, 2024 Category: ENT & OMF Source Type: research
Can predictive factors determine the time to treatment initiation for oral and oropharyngeal cancer? A classification and regression tree analysis
by D ébora Rosana Alves Braga Silva Montagnoli, Vitória Ferreira Leite, Yasmim Silva Godoy, Vitória Marçolla Lafetá, Edmilson Antônio Pereira Junior, Akhilanand Chaurasia, Maria Cássia Ferreira Aguiar, Mauro Henrique Nogueira Guimarães Abreu, Renata Castro Martins
This ecological study aimed to identify the factors with the greatest power to discriminate the proportion of oral and oropharyngeal cancer (OOC) records with time to treatment initiation (TTI) within 30 days of diagnosis in Brazilian municipalities. A descriptive analysis was performed on the var iables grouped into five dimensions related to patient ch...
Source: PLoS One - April 17, 2024 Category: Biomedical Science Authors: D ébora Rosana Alves Braga Silva Montagnoli Source Type: research
Comparison of 3-year local control using DAHANCA radiotherapy guidelines before and after implementation of five millimetres geometrical GTV to high-dose CTV margin
Primary radiotherapy is the preferred anatomy-preserving treatment for squamous cell carcinomas in the head and neck region (HNSCC), excluding carcinomas in the oral cavity or certain localised oropharyngeal/laryngeal cancers amenable to surgery[1,2]. Platinum-based chemo-radiotherapy (CRT) using IMRT/VMAT techniques is the contemporary standard for loco-regionally advanced HNSCC, with a five-year risk of local and regional failures of 23.5 % and 20.2 %, respectively, using altered fractionation regimes [3]. (Source: Radiotherapy and Oncology)
Source: Radiotherapy and Oncology - April 16, 2024 Category: Radiology Authors: Ruta Zukauskaite Ruta, Morten Horsholt Kristensen, Jesper Grau Eriksen, J ørgen Johansen, Eva Samsøe, Lars Johnsen, Camilla Kjær Lønkvist, Cai Grau, Christian Rønn Hansen Tags: Original Article Source Type: research
A Prospective Cohort Study on Neck Lymph Node Mapping in Oral Cancers Using Methylene Blue Dye
AbstractIn the current scenario, the management of N0 neck in early-stage oral cancer is debatable, whether or not they should undergo elective neck dissection. Most of the time these patients are either over-treated or under-treated. Sentinel lymph node (SLN) biopsy is a good option to identify occult LN in this cohort of patients for guiding neck dissection. With a focus on SLN biopsy using methylene blue dye, this study aims to evaluate its feasibility and accuracy in node-negative oral squamous cell carcinoma. A prospective observational study was conducted involving operable squamous cell carcinoma patients with clini...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - April 16, 2024 Category: ENT & OMF Source Type: research
New | phs002503.v1.p1 | GWA Study of Oral Cavity, Pharynx and Larynx Cancers in European, and North and South American Populations - CIDR
GWA Study of Oral Cavity, Pharynx and Larynx Cancers in European, and North and South American Populations - CIDR (study page |release notes) (Source: dbGaP, the database of Genotypes and Phenotypes)
Source: dbGaP, the database of Genotypes and Phenotypes - April 15, 2024 Category: Genetics & Stem Cells Tags: StudyRelease Source Type: research
Partial recovery of peripheral blood monocyte subsets in head and neck squamous cell carcinoma patients upon radio(chemo)therapy is associated with decreased plasma CXCL11
Head and neck squamous cell carcinoma (HNSCC) represents a common and heterogeneous malignancy of the oral cavity, pharynx and larynx. Surgery and radio(chemo)therapy are the standard treatment options and als... (Source: BMC Cancer)
Source: BMC Cancer - April 12, 2024 Category: Cancer & Oncology Authors: Christian Idel, Jonas Fleckner, Kirstin Pl ötze-Martin, Lotte Werner, Dirk Rades, Marie-Nicole Theodoraki, Linda Hofmann, Diana Huber, Anke Leichtle, Thomas K. Hoffmann, Karl-Ludwig Bruchhage and Ralph Pries Tags: Research Source Type: research
