Comparison of 3-year local control using DAHANCA radiotherapy guidelines before and after implementation of five millimetres geometrical GTV to high-dose CTV margin

Primary radiotherapy is the preferred anatomy-preserving treatment for squamous cell carcinomas in the head and neck region (HNSCC), excluding carcinomas in the oral cavity or certain localised oropharyngeal/laryngeal cancers amenable to surgery[1,2]. Platinum-based chemo-radiotherapy (CRT) using IMRT/VMAT techniques is the contemporary standard for loco-regionally advanced HNSCC, with a five-year risk of local and regional failures of 23.5  % and 20.2 %, respectively, using altered fractionation regimes [3].

https://www.thegreenjournal.com/article/S0167-8140(24)00206-8/fulltext?rss=yes

Source: Radiotherapy and Oncology - April 16, 2024 Category: Radiology Authors: Ruta Zukauskaite Ruta, Morten Horsholt Kristensen, Jesper Grau Eriksen, J ørgen Johansen, Eva Samsøe, Lars Johnsen, Camilla Kjær Lønkvist, Cai Grau, Christian Rønn Hansen Tags: Original Article Source Type: research