Botanical drug is shown to help patients with head and neck cancers
In a UCLA-led phase I clinical trial, a new plant-based drug called APG-157 showed signs of helping patients fight oral and oropharyngeal cancers. These cancers are located in the head and the neck. APG-157 is made up of multiple compounds produced by plants, including curcumin. UCLA Jonsson Comprehensive Cancer Center researchers found that treatment with this botanical drug resulted in (Source: World Pharma News)
Source: World Pharma News - February 6, 2020 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Gaps in cure rate appear linked to race and insurance status for common HPV-related cancer
(National Comprehensive Cancer Network) Largest population-based analysis to date on outcomes for HPV-positive oropharyngeal squamous cell carcinoma of the head and neck (SCCHN) finds significant racial and socioeconomic disparities, according to new research in JNCCN-Journal of the National Comprehensive Cancer Network. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 6, 2020 Category: Cancer & Oncology Source Type: news

Botanical drug is shown to help patients with head and neck cancers
(University of California - Los Angeles Health Sciences) In a UCLA-led phase I clinical trial, a new plant-based drug called APG-157 showed signs of helping patients fight oral and oropharyngeal cancers. These cancers are located in the head and the neck. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 6, 2020 Category: International Medicine & Public Health Source Type: news

Nimotuzumab-cisplatin-radiation versus cisplatin-radiation in HPV negative oropharyngeal cancer
In this study, locally advanced head and neck cancer patients undergoing definitive chemoradiation were randomly allocated to weekly cisplatin - radiation {CRT arm} or nimotuzumab -weekly cisplatin -radiation {NCRT arm}. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 6, 2020 Category: Cancer & Oncology Source Type: news

Botanical drug is shown to help patients with head and neck cancers
In this study, UCLA researchers found that when APG-157 is taken through oral mucosal absorption, patients have high levels of curcumin circulating in their blood and absorbed by cancer tissues.METHODUCLA researchers conducted the study of APG-157 comparing 12 people who had oral and oropharyngeal cancer with a control group of 13 people who did not have cancer. The reason both the people with cancer and without cancer were part of the study was to show that the drug was not toxic to either people with cancer or those without cancer.The medication was given each hour for three hours and was delivered as a lozenge that slow...
Source: UCLA Newsroom: Health Sciences - February 6, 2020 Category: Universities & Medical Training Source Type: news

The incidence of oropharyngeal cancer and rate of human papillomavirus vaccination coverage in Florida, 2011 through 2015.
CONCLUSIONS:The authors found relatively higher and increasing incidence rate of OPC in Florida and lower rate of HPV vaccination among adolescents in Florida than in the nation overall.PRACTICAL IMPLICATIONS:The trends illustrated may stimulate policy changes to increase HPV vaccination for children and enhance the understanding of its benefits. (Source: Dental Technology Blog)
Source: Dental Technology Blog - January 23, 2020 Category: Dentistry Source Type: news

Short-Term Mortality Is Lower When Oropharynx Cancer Is HPV-Positive Short-Term Mortality Is Lower When Oropharynx Cancer Is HPV-Positive
Short-term mortality among patients with oropharynx cancer (OPC) is lower when the cancer is positive for the human papillomavirus (HPV), a review of data finds.Reuters Health Information (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - January 14, 2020 Category: Allergy & Immunology Tags: Hematology-Oncology News Source Type: news

Mortality Risk in Oropharynx Cancer Varies Based on HPV Status
Patients with OPC with HPV - negative tumors have increased risk for head and neck cancer mortality (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - January 13, 2020 Category: Cancer & Oncology Tags: Family Medicine, Gynecology, Infections, Internal Medicine, Oncology, ENT, Pathology, Journal, Source Type: news

Mortality Risk in Oropharynx Cancer Varies Based on HPV Status
MONDAY, Jan. 13, 2020 -- For patients with oropharynx cancer, the rates of head and neck cancer (HNC) mortality and competing mortality vary depending on human papillomavirus (HPV) status, with increased risks for HNC mortality and competing... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 13, 2020 Category: Pharmaceuticals Source Type: news

HPV status may affect risk of early death in patients with oropharynx cancer
(Wiley) New research published in CANCER indicates that there is a higher risk of early death among patients with oropharynx cancer when not caused by human papillomavirus (HPV), than those whose tumors are HPV-positive. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 13, 2020 Category: International Medicine & Public Health Source Type: news

Improved Saliva Test Aids Detection of HPV-16 Improved Saliva Test Aids Detection of HPV-16
Use of acoustofluidic separation technology (AFS) doubles detection of oropharyngeal cancer-associated human papillomavirus-16 (HPV-OPC) in saliva, according to an international group of investigatorsReuters Health Information (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - December 27, 2019 Category: Infectious Diseases Tags: Infectious Diseases News Source Type: news

Saliva test shows promise for earlier and easier detection of mouth and throat cancer
(Elsevier) Unfortunately, cancers that occur in the back of the mouth and upper throat are often not diagnosed until they become advanced. A report in The Journal of Molecular Diagnostics describes the use of acoustofluidics, a new non-invasive method that analyzes saliva for the presence of human papilloma virus (HPV)-16, the pathogenic strain associated with oropharyngeal cancers (OPCs). This novel technique detected OPC in whole saliva in 40 percent of patients tested and 80% of confirmed OPC patients. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 13, 2019 Category: International Medicine & Public Health Source Type: news

Fewer Cases of Radiation-Induced Xerostomia Found With Acupuncture
TUESDAY, Dec. 10, 2019 -- Acupuncture results in significantly fewer and less severe symptoms of radiation-induced xerostomia (RIX) among patients with oropharyngeal or nasopharyngeal carcinoma, according to a study published online Dec. 6 in JAMA... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 10, 2019 Category: Pharmaceuticals Source Type: news

Cisplatin cost  effective for HPV-positive oropharyngeal cancer
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - December 1, 2019 Category: Drugs & Pharmacology Source Type: news

High Rates of Oropharynx Cancer Tied to HPV
Data from a new study show the importance of taking preventative measures against contracting human papillomavirus, including urging patients to get the HPV vaccine. (Source: CancerNetwork)
Source: CancerNetwork - September 11, 2019 Category: Cancer & Oncology Authors: Leah Lawrence Source Type: news

FDG-PET/CT helps predict tuberculosis relapse
When FDG-PET/CT scans reveal lingering metabolic activity in the lungs of tuberculosis...Read more on AuntMinnie.comRelated Reading: 2 new PET tracers may best FDG in cancer imaging Later PET/CT follow-up helps for oropharyngeal cancer PET shows efficacy of tuberculosis meningitis drug PET/CT key to NIH's tuberculosis research plan Can AI accurately diagnose tuberculosis from chest x-rays? (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - August 28, 2019 Category: Radiology Source Type: news

Questions Remain About the Role of Transoral Surgery for Oropharyngeal Cancer
Researchers compared the swallowing-related quality-of-life scores of patients with  oropharyngeal squamous cell carcinoma who received radiotherapy and patients who received transoral robotic surgery with neck dissection. (Source: CancerNetwork)
Source: CancerNetwork - August 19, 2019 Category: Cancer & Oncology Authors: Leah Lawrence Source Type: news

Should Surveillance Schedules Apply to HPV-Associated Oropharyngeal Squamous Cell Carcinomas?
A new study looked at what methods were used to detect recurrences of  human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma to see if surveillance guidelines recommended by the National Comprehensive Cancer Center were effective. (Source: CancerNetwork)
Source: CancerNetwork - August 16, 2019 Category: Cancer & Oncology Authors: Leah Lawrence Source Type: news

Doctors find dentures in man's throat 8 days after surgery
Removable dentures got stuck in a 72-year-old man's throat during surgery to...Read more on AuntMinnie.comRelated Reading: 3-month PET/CT helps track oropharyngeal cancer CBCT outstrips growth in all other dental x-ray segments US-guided core biopsy best for salivary gland tumors Intraoperative CT fine-tunes maxillofacial surgery Proton therapy helps oropharyngeal patients (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - August 13, 2019 Category: Radiology Source Type: news

More HPV vaccinations could prevent cancer in 1,300 Californians
FINDINGSBased on a 2017 rate of vaccination against HPV among a group of California 20-year-olds, researchers estimate that this group is at risk for an excess of 1,352 cases of cancer that could be prevented with a 99.5% vaccination rate. Treatment for these preventable cancers would cost the health care system $52.2 million. The size of the group was 296,525 people, the approximate number of 20-year-olds in California in 2017.BACKGROUNDHuman papillomavirus, or HPV, is the most common sexually transmitted infection in the United States and is linked to seven types of cancer: cervical, vaginal, vulvar, penile, rectal, anal...
Source: UCLA Newsroom: Health Sciences - July 2, 2019 Category: Universities & Medical Training Source Type: news

HPV Vaccine Ages For Males Should Be Extended, According To CDC Panel
By Jacqueline Howard, CNN (CNN) — The US Centers for Disease Control and Prevention’s Advisory Committee on Immunization Practices, known as ACIP, voted unanimously on Wednesday to recommend HPV vaccines for both boys and girls and men and women through age 26. Previously the CDC recommended that teen girls and young women who had not been adequately vaccinated receive the human papillomavirus vaccine through age 26, but the recommendation for teen boys and young men only went through age 21. The CDC’s recommendation that children start receiving two doses of the HPV vaccine around 11 or 12...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - June 27, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN HPV vaccine Source Type: news

Mayo Clinic Minute: Improved treatments for head and neck cancer
About 70% of cancers in the oropharynx, which includes the tonsils, soft palate and base of the tongue, are linked to the HPV virus, according to the Centers for Disease Control and Prevention. So it's important to talk to your health care provider about the HPV vaccine, especially if you are 26 years old or [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - June 26, 2019 Category: Databases & Libraries Source Type: news

HPV16 Antibodies Can Develop Long Before Throat Cancer Diagnosis
THURSDAY, June 13, 2019 -- Seroconversion to human papillomavirus type 16 (HPV16)-E6 antibody positivity can occur decades before diagnosis of oropharyngeal squamous cell carcinoma (OPSCC), according to a study published online June 12 in the Annals... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 13, 2019 Category: Pharmaceuticals Source Type: news

Robotic Surgery vs Radiation in Oropharyngeal Cancer Robotic Surgery vs Radiation in Oropharyngeal Cancer
The only trial directly comparing the two modalities found better swallowing outcomes with radiotherapy, but no difference in survival.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 12, 2019 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Robotic surgery for throat cancer not superior to radiation therapy, study finds
(Lawson Health Research Institute) In 2012, scientists at Lawson Health Research Institute launched the world's first clinical trial comparing robotic surgery to radiation therapy for the treatment of oropharyngeal cancer (cancer at the back of the throat). The team is now reporting findings from the seven-year study which challenges beliefs that surgery leads to better swallowing outcomes, suggesting instead that radiation results in better quality of life for patients. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 6, 2019 Category: Cancer & Oncology Source Type: news

2 new PET tracers may best FDG in cancer imaging
Cancer detection could receive a boost from two new radiotracers that have...Read more on AuntMinnie.comRelated Reading: Later PET/CT follow-up helps for oropharyngeal cancer Ga-68 PSMA-11 PET/MRI improves prostate cancer detection New PET tracer could aid melanoma detection FDG-PET/CT fails for peripheral T-cell lymphoma outcomes PET/CT predicts success of rad therapy for spinal mets (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - March 14, 2019 Category: Radiology Source Type: news

Later PET/CT follow-up helps for oropharyngeal cancer
Using PET/CT for follow-up at a later interval than what's recommended by existing...Read more on AuntMinnie.comRelated Reading: FDG-PET/CT aids in melanoma treatment assessment CT lung screening can catch recurring head, neck cancer ASTRO: Blood test confirms HPV-related cancer remission FDG-PET/CT fails for peripheral T-cell lymphoma outcomes FDG-PET/CT helps stage men with breast cancer, too (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - March 11, 2019 Category: Radiology Source Type: news

New study shows HPV not likely transmittable through the hand
(McGill University) Commonly known as HPV, Human papillomavirus is a virus that infects the skin and genital area, in many cases leading to a variety of genital, anal, and oropharyngeal cancers in men and women. Strong evidence exists showing that penetrative genital sex and oral sex can transmit HPV. However, while HPV is also often detected in the hands, the question of whether hand-genital contacts can transmit HPV has long been a source of debate among researchers. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 11, 2019 Category: International Medicine & Public Health Source Type: news

HPV Gene Expression Signatures, Prognosis in Cervical Cancers
Cancer Network spoke with Curtis Pickering, PhD, about prognostic gene expression signatures for HPV-positive oropharyngeal and cervical cancers. (Source: CancerNetwork)
Source: CancerNetwork - January 28, 2019 Category: Cancer & Oncology Authors: Bryant Furlow Source Type: news

Cisplatin Superior to Cetuximab for HPV + Oropharyngeal Cancer
Toxicity similar in two treatment groups at 24 months, but worse tumor control with cetuximab (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - December 17, 2018 Category: Cancer & Oncology Tags: Oncology, ENT, Pharmacy, Radiology, Journal, Source Type: news

Cisplatin Superior to Cetuximab for HPV+ Oropharyngeal Cancer
MONDAY, Dec. 17, 2018 -- For treatment of human papillomavirus (HPV)-positive low-risk oropharyngeal cancer, cetuximab shows no benefit compared with the standard cisplatin regimen in terms of reduced toxicity and results in worse tumor control,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 17, 2018 Category: Pharmaceuticals Source Type: news

ASTRO: Oropharynx CA Survival Rates Worse With RT/Cetuximab
FRIDAY, Oct. 26, 2018 -- For patients with locoregionally advanced human papillomavirus (HPV)-related oropharynx cancer, radiation/cetuximab results in inferior overall and progression-free survival versus radiation/cisplatin, according to a study... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 26, 2018 Category: Pharmaceuticals Source Type: news

Liquid Biopsy Confirms Remission in HPV Oropharyngeal Cancer Liquid Biopsy Confirms Remission in HPV Oropharyngeal Cancer
A plasma circulating tumor human papillomavirus (HPV) DNA test had a negative predictive value of 100% and predicts patients at risk for cancer recurrence.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 24, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

ASTRO: Blood test confirms HPV-related cancer remission
A biomarker blood test can accurately determine if patients with oropharyngeal...Read more on AuntMinnie.comRelated Reading: ASTRO: Prostate RT works better than expected in black men ASTRO: SABR is effective for oligometastatic cancers ASTRO: Weekly breast radiation therapy is safe ASTRO: AI's rad therapy future is in predicting outcomes ASTRO: SBRT works well for less risky prostate cancer (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - October 24, 2018 Category: Radiology Source Type: news

Biomarker blood test confirms remission in patients with HPV+ oral cancer
(American Society for Radiation Oncology) A highly sensitive blood test that detects minute traces of cancer-specific DNA has been shown to accurately determine whether patients with HPV-related oropharyngeal squamous cell carcinoma (OPSCC) are free from cancer following radiation therapy. Findings will be presented today at the 60th Annual Meeting of the American Society for Radiation Oncology (ASTRO). (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 23, 2018 Category: Cancer & Oncology Source Type: news

HPV blood test shows promise for tracking head and neck cancer after treatment
(UNC Lineberger Comprehensive Cancer Center) Researchers will present preliminary findings at the 60th Annual Meeting of the American Society for Radiation Oncology in San Antonio on Tuesday, Oct. 23, from a study that evaluated a blood test for HPV-linked oropharyngeal squamous cell carcinoma. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 23, 2018 Category: Cancer & Oncology Source Type: news

Patients with HPV-positive oropharynx cancer should receive chemoradiation
(European Society for Medical Oncology) Patients with human papilloma virus (HPV)-positive throat cancer should receive chemoradiotherapy rather than cetuximab with radiotherapy, according to late-breaking research reported at the ESMO 2018 Congress in Munich. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 22, 2018 Category: International Medicine & Public Health Source Type: news

RT and Surgery Appear Equally Viable for Oropharyngeal Cancer
(MedPage Today) -- But chemo add-on to RT was tied to increased gastrostomy dependence (Source: MedPage Today Radiology)
Source: MedPage Today Radiology - September 25, 2018 Category: Radiology Source Type: news

Trends in HPV-Associated Cancers -- United States, 1999-2015 Trends in HPV-Associated Cancers -- United States, 1999-2015
This report examined trends in cervical cancer, as well as oropharyngeal, vulvar, vaginal, penile, and anal cancers.Morbidity & Mortality Weekly Report (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 19, 2018 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

Late Lower Cranial Neuropathy in Oropharyngeal Cancer Patients
Survivors of oropharyngeal cancers who developed late lower cranial neuropathy reported having worse treatment-related symptoms. (Source: CancerNetwork)
Source: CancerNetwork - September 14, 2018 Category: Cancer & Oncology Authors: Leah Lawrence Source Type: news

Total of 43,371 New Cases of HPV - Associated Cancers in 2015
Decreases in cervical cancer, vaginal SCC from 1999 to 2015; increases in oropharyngeal, anal, vulvar SCC (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - September 11, 2018 Category: Cancer & Oncology Tags: Family Medicine, Gynecology, Infections, Internal Medicine, Nursing, Oncology, Pathology, Journal, Source Type: news

Total of 43,371 New Cases of HPV-Associated Cancers in 2015
TUESDAY, Sept. 11, 2018 -- A total of 43,371 new cases of human papillomavirus (HPV)-associated cancers were reported in 2015, with oropharyngeal squamous cell carcinoma (SCC) being the most common HPV-associated cancer, according to research... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - September 11, 2018 Category: Pharmaceuticals Source Type: news

Test Oropharyngeal Cancers for HPV
(MedPage Today) -- ASCO endorses CAP guideline (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - September 10, 2018 Category: American Health Source Type: news

Top HPV-Associated Cancer Is Now Oropharyngeal
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - August 24, 2018 Category: General Medicine Source Type: news

CDC: Top HPV-Associated Cancer Is Now Oropharyngeal CDC: Top HPV-Associated Cancer Is Now Oropharyngeal
Also, the Centers for Disease Control and Prevention reports that over the past 15 years, women's HPV-associated cancers are in decline and men's are on the rise.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 23, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

No Change in Standard of Care for HPV+ Oropharyngeal Cancer No Change in Standard of Care for HPV+ Oropharyngeal Cancer
Interim results of a large phase III trial showed that patients treated with a cetuximab regimen has worse survival than those treated with cisplatin plus radiation therapy.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 20, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Cetuximab with radiation found to be inferior to standard treatment in HPV-positive oropharyngeal cancer
. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - August 14, 2018 Category: American Health Source Type: news

Cetuximab+RT found to be inferior to standard treatment in HPV+ oropharyngeal cancer
(NIH/National Cancer Institute) An interim analysis of data from a randomized clinical trial of patients with human papillomavirus (HPV)-positive oropharyngeal cancer found that treatment with radiation therapy and cetuximab is associated with worse overall and progression-free survival compared to the current standard treatment with radiation and cisplatin. The trial was designed to see if cetuximab with radiation would be less toxic than cisplatin with radiation without compromising survival for patients with the disease. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 14, 2018 Category: Cancer & Oncology Source Type: news

Older Adults Increasingly Have HPV + Oropharyngeal Cancers
Regardless of age, favorable survival conferred by an HPV - positive tumor status (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - June 13, 2018 Category: Cancer & Oncology Tags: Oncology, ENT, Pathology, Geriatrics, Journal, Source Type: news