A discrete choice experiment on price and flavour effects on the appeal of nicotine products: a pilot study among young adults in Switzerland
CONCLUSIONS: Our Discrete Choice Experiment suggests that, for the Swiss context, limiting the availability of flavours for alternative smoking products has the potential to reduce their appeal to non-smokers by 86% and that a small but significant increase in prices to CHF 15 for cigarettes, ENDS and HTS could lead to a major (around 66%) decrease in their appeal.PMID:38579318 | DOI:10.57187/s.3733 (Source: Swiss Medical Weekly)
Source: Swiss Medical Weekly - April 5, 2024 Category: General Medicine Authors: Larissa Merz Milo A Puhan Miquel Serra-Burriel Source Type: research
Adaptation and Validation of the Hooked on Nicotine Checklist (HONC) with Spanish Adolescents
CONCLUSION: This study makes the Spanish version of the HONC available to researchers and clinicians, so that it can be used with sufficient psychometric guarantees.PMID:38580487 | DOI:10.1016/j.arbres.2024.03.020 (Source: Archivos de Bronconeumologia)
Source: Archivos de Bronconeumologia - April 5, 2024 Category: Respiratory Medicine Authors: Nuria Garc ía-Couceiro Sion Kim-Harris Patricia G ómez Manuel Isorna Antonio Rial Source Type: research
Protective effect of enicostemma axillare - swertiamarin on oxidative stress against nicotine-induced liver damage in sd rats
CONCLUSION: The results of the current study show that nicotine can seriously harm liver tissue and that Swertiamarin can prevent the harmful effects of nicotine on rat liver. Future research is necessary to delve deeply into the mechanisms behind Swertiamarin protective impact against nicotine-induced hepatotoxicity.PMID:38579927 | DOI:10.1016/j.pharma.2024.03.009 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - April 5, 2024 Category: Drugs & Pharmacology Authors: Rajini Kolure V Nachammai Sneha Thakur Ramreddy Godela D Sherisha Bhavani S N Manjula Source Type: research
Protective effect of Enicostemma axillare - Swertiamarin on oxidative stress against nicotine-induced liver damage in SD rats
CONCLUSION: The results of the current study show that nicotine can seriously harm liver tissue and that swertiamarin can prevent the harmful effects of nicotine on rat liver. Future research is necessary to delve deeply into the mechanisms behind swertiamarin protective impact against nicotine-induced hepatotoxicity.PMID:38579927 | DOI:10.1016/j.pharma.2024.03.009 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - April 5, 2024 Category: Drugs & Pharmacology Authors: Rajini Kolure Nachammai Vinaitheerthan Sneha Thakur Ramreddy Godela Sherisha Bhavani Doli Manjula Santhepete Nanjundaiah Source Type: research
Effect of implementation strategies on the routine provision of antenatal care addressing smoking in pregnancy: study protocol for a non-randomised stepped-wedge cluster controlled trial
This study aims to determine the effectiveness and cost effectiveness of implementation strategies in increasing the routine provision of recommended antenatal care for smoking cessation in public maternity services.
Methods and analysis
A non-randomised stepped-wedge cluster-controlled trial will be conducted in maternity services across three health sectors in New South Wales, Australia. Implementation strategies including guidelines and procedures, reminders and prompts, leadership support, champions, training and monitoring and feedback will be delivered sequentially to each sector over 4 months. Primary outcome measu...
Source: BMJ Open - April 5, 2024 Category: General Medicine Authors: Daly, J. B., Doherty, E., Tully, B., Wiggers, J., Hollis, J., Licata, M., Foster, M., Tzelepis, F., Lecathelinais, C., Kingsland, M. Tags: Open access, Health services research Source Type: research
Multi-endpoint in vitro toxicological assessment of snus and tobacco-free nicotine pouch extracts
In conclusion these assays contribute to the weight of evidence assessment of the potential comparative health risks of NPs and snus.PMID:38575247 | DOI:10.1016/j.mrgentox.2024.503738 (Source: Cell Research)
Source: Cell Research - April 4, 2024 Category: Cytology Authors: Fan Yu Emma Bishop Fabio Miazzi Rhian Evans David Smart Damien Breheny David Thorne Source Type: research
Regulation of sexual commitment in malaria parasites - a complex affair
Curr Opin Microbiol. 2024 Apr 3;79:102469. doi: 10.1016/j.mib.2024.102469. Online ahead of print.ABSTRACTMalaria blood stage parasites commit to either one of two distinct cellular fates while developing within erythrocytes of their mammalian host: they either undergo another round of asexual replication or they differentiate into nonreplicative transmissible gametocytes. Depending on the state of infection, either path may support or impair the ultimate goal of human-to-human transmission via the mosquito vector. Malaria parasites therefore evolved strategies to control investments into asexual proliferation versus gameto...
Source: Current Opinion in Microbiology - April 4, 2024 Category: Microbiology Authors: Till S Voss Nicolas Mb Brancucci Source Type: research
Multi-endpoint in vitro toxicological assessment of snus and tobacco-free nicotine pouch extracts
In conclusion these assays contribute to the weight of evidence assessment of the potential comparative health risks of NPs and snus.PMID:38575247 | DOI:10.1016/j.mrgentox.2024.503738 (Source: Cell Research)
Source: Cell Research - April 4, 2024 Category: Cytology Authors: Fan Yu Emma Bishop Fabio Miazzi Rhian Evans David Smart Damien Breheny David Thorne Source Type: research
Differential Intervention Outcomes Among Fathers Who Commit Domestic and Family Violence: The Influence of Parental Relationship Status
ConclusionThis study provides early support for improvements in CD participants ’ fathering, parental alliance, and family functioning, most substantially for partnered fathers, though findings should be further investigated with larger cohorts. (Source: Journal of Family Violence)
Source: Journal of Family Violence - April 4, 2024 Category: Psychiatry & Psychology Source Type: research
Lethal and sublethal effects of programmed cell death pathways on hematopoietic stem cells
In multicellular organisms, the capacity of cells to commit suicide is critical to maintain homeostasis in high turnover tissues. In young adult humans, around 4 million cells are estimated to turn over every second, about 90% of which are of hematopoietic origin [1]. Based on a mathematical analysis that integrates ubiquity, mass, and lifespan of all major cell types in a human body, approximately 2 ×1011 red blood cells, 6×1010 neutrophils, 5×109 B cells, 2×109 T cells, and 1×1011 platelets are predicted to be generated every day, but our remarkably constant blood cell counts indicate that the same number of cells a...
Source: Experimental Hematology - April 3, 2024 Category: Hematology Authors: Yuta Yamada, Zhiqian Zheng, Alaa K. Jad, Masayuki Yamashita Tags: Review Source Type: research
Synthesis, biological activity, and binding modes of novel guanidino-containing neonicotinoid derivatives
New J. Chem., 2024, Accepted Manuscript DOI: 10.1039/D4NJ00228H, PaperLi Jianyang, jing miao, Peibo Liang, yiyang Wang, xingyue zhou, Yanhong Dong, Huizhe Lu, Jian-Jun Zhang In the present study, the guanidine moiety from natural products was introduced into neonicotinoid insecticides, and a series of nicotine derivatives with guanidine functional groups were synthesized. Bioactivity assays reveal... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - New J. Chem. latest articles)
Source: RSC - New J. Chem. latest articles - April 1, 2024 Category: Chemistry Authors: Li Jianyang Source Type: research
Pharmacist-implemented intervention to surmount COVID-19 vaccination hesitancy in adults with substance use disorders
CONCLUSION: Pharmacist-administered intervention produced motivation for vaccination in a number of recipients; however, receptivity to the intervention was not related to SUD severity.PMID:38557904 | DOI:10.1093/ajhp/zxae095 (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - April 1, 2024 Category: Drugs & Pharmacology Authors: Zoe Karavolis Emily Thacker Tanya Fabian Antoine Douaihy Maureen Reynolds Levent Kirisci Ralph Tarter Source Type: research
Pharmacist-implemented intervention to surmount COVID-19 vaccination hesitancy in adults with substance use disorders
CONCLUSION: Pharmacist-administered intervention produced motivation for vaccination in a number of recipients; however, receptivity to the intervention was not related to SUD severity.PMID:38557904 | DOI:10.1093/ajhp/zxae095 (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - April 1, 2024 Category: Drugs & Pharmacology Authors: Zoe Karavolis Emily Thacker Tanya Fabian Antoine Douaihy Maureen Reynolds Levent Kirisci Ralph Tarter Source Type: research
Addressing Cardiovascular Toxicity Risk of Electronic Nicotine Delivery Systems in the Twenty-First Century: "What Are the Tools Needed for the Job?" and "Do We Have Them?"
Cardiovasc Toxicol. 2024 Mar 31. doi: 10.1007/s12012-024-09850-9. Online ahead of print.ABSTRACTCigarette smoking is positively and robustly associated with cardiovascular disease (CVD), including hypertension, atherosclerosis, cardiac arrhythmias, stroke, thromboembolism, myocardial infarctions, and heart failure. However, after more than a decade of ENDS presence in the U.S. marketplace, uncertainty persists regarding the long-term health consequences of ENDS use for CVD. New approach methods (NAMs) in the field of toxicology are being developed to enhance rapid prediction of human health hazards. Recent technical advanc...
Source: Cardiovascular Toxicology - March 31, 2024 Category: Cardiology Authors: Mark Chandy Thomas Hill Nerea Jimenez-Tellez Joseph C Wu S Emma Sarles Edward Hensel Qixin Wang Irfan Rahman Daniel J Conklin Source Type: research
Addressing Cardiovascular Toxicity Risk of Electronic Nicotine Delivery Systems in the Twenty-First Century: "What Are the Tools Needed for the Job?" and "Do We Have Them?"
Cardiovasc Toxicol. 2024 Mar 31. doi: 10.1007/s12012-024-09850-9. Online ahead of print.ABSTRACTCigarette smoking is positively and robustly associated with cardiovascular disease (CVD), including hypertension, atherosclerosis, cardiac arrhythmias, stroke, thromboembolism, myocardial infarctions, and heart failure. However, after more than a decade of ENDS presence in the U.S. marketplace, uncertainty persists regarding the long-term health consequences of ENDS use for CVD. New approach methods (NAMs) in the field of toxicology are being developed to enhance rapid prediction of human health hazards. Recent technical advanc...
Source: Atherosclerosis - March 31, 2024 Category: Cardiology Authors: Mark Chandy Thomas Hill Nerea Jimenez-Tellez Joseph C Wu S Emma Sarles Edward Hensel Qixin Wang Irfan Rahman Daniel J Conklin Source Type: research
