Aspects that facilitate access to care for viral hepatitis: An evaluative research
CONCLUSIONS: The results are crucial for improving comprehensiveness, but necessitate managerial efforts to enhance regional governance.PMID:38477774 | PMC:PMC10926966 | DOI:10.1590/1516-3180.2023.0078.R1.29112023 (Source: Sao Paulo Medical Journal)
Source: Sao Paulo Medical Journal - March 13, 2024 Category: General Medicine Authors: Josu é Souza Gleriano Carlise Krein Lucieli Dias Pedreschi Chaves Source Type: research

The Fagerstr öm Test for Nicotine Dependence, as a prognostic factor, in current smokers with and without COPD: A cross-sectional study in northern Greece
CONCLUSION: The Fagerström score appears to indicate a higher probability for COPD and lung function deterioration when assessed along with age in current smokers. Smoking cessation support programs are fundamental to COPD prevention and management.PMID:38476003 | PMC:PMC10935750 | DOI:10.1177/14799731241235213 (Source: Chronic Respiratory Disease)
Source: Chronic Respiratory Disease - March 13, 2024 Category: Respiratory Medicine Authors: Efthymia Papadopoulou Anna-Bettina Haidich Alexander Mathioudakis Drosos Tsavlis Konstantina Papadopoulou Rena Oikonomidou Panagiotis Bogiatzidis Stavros Tryfon Source Type: research

Structural Impact Assessment of Cytochrome P450 2A13 Polymorphisms Using Molecular Dynamics Simulations
This study aimed to unravel the mechanism underlying the diminished enzymatic activity of CYP2A13 variants by investigating their three-dimensional structures through molecular dynamics (MD) simulations. For each variant, MD simulations of 1000 ns were performed, and the obtained results were compared with those of the wild type. The findings indicated alterations in the interaction with heme in CYP2A13.4, .6, .8, and .9. In the case of CYP2A13.5, observable effects on the helix structure related to the interaction with the redox partner were identified. These conformational changes were sufficient to cause a decrease in e...
Source: Biological and Pharmaceutical Bulletin - March 13, 2024 Category: Drugs & Pharmacology Authors: Koichi Kato Tomoki Nakayoshi Sho Hioki Masahiro Hiratsuka Yoshinobu Ishikawa Eiji Kurimoto Akifumi Oda Source Type: research

Aspects that facilitate access to care for viral hepatitis: An evaluative research
CONCLUSIONS: The results are crucial for improving comprehensiveness, but necessitate managerial efforts to enhance regional governance.PMID:38477774 | PMC:PMC10926966 | DOI:10.1590/1516-3180.2023.0078.R1.29112023 (Source: Sao Paulo Medical Journal)
Source: Sao Paulo Medical Journal - March 13, 2024 Category: General Medicine Authors: Josu é Souza Gleriano Carlise Krein Lucieli Dias Pedreschi Chaves Source Type: research

The Fagerstr öm Test for Nicotine Dependence, as a prognostic factor, in current smokers with and without COPD: A cross-sectional study in northern Greece
CONCLUSION: The Fagerström score appears to indicate a higher probability for COPD and lung function deterioration when assessed along with age in current smokers. Smoking cessation support programs are fundamental to COPD prevention and management.PMID:38476003 | PMC:PMC10935750 | DOI:10.1177/14799731241235213 (Source: Chronic Respiratory Disease)
Source: Chronic Respiratory Disease - March 13, 2024 Category: Respiratory Medicine Authors: Efthymia Papadopoulou Anna-Bettina Haidich Alexander Mathioudakis Drosos Tsavlis Konstantina Papadopoulou Rena Oikonomidou Panagiotis Bogiatzidis Stavros Tryfon Source Type: research