Preventive effects of crocin, a natural compound from saffron, against nicotine ‑induced oxidative stress and neurobehavioral disturbances
In this study, we explore the neuroprotective effects of crocin, a bioactive agent commonly found in saffron - a spice derived from the flower of Crocus sativus - using a rat model. The dose‑dependent effects of crocin were evaluated in nicotine‑induced neurodegeneration and compared with a control group. Neurobehavioral changes, assessed through the elevated plus maze, the open field test, the forced swim test, and the Morris water maze, as well as oxidative stress in the hippocampus, were evaluated. Interestingly, nicotine administration resulted in depression, anxiety, and abnormal motor and cognitive functions, whi...
Source: Acta Neurobiologiae Experimentalis - April 8, 2024 Category: Neurology Authors: Majid Motaghinejad Manijeh Motevalian Antoni Sureda Source Type: research
Solidarity Over Charity: Mutual Aid as a Moral Alternative to Effective Altruism
Kennedy Inst Ethics J. 2023;33(2):167-199. doi: 10.1353/ken.2023.a904082.ABSTRACTEffective Altruism is a popular social movement that encourages individuals to donate to organizations that effectively address humanity's most severe poverty. However, because Effective Altruists are committed to doing the most good in the most effective ways, they often argue that it is wrong to help those nearest to you. In this article, I target a major subset of Effective Altruists who consider it a moral obligation to do the most good possible. Call these Obligation-Oriented Effective Altruists (OOEAs), and their movement Obligation-Orie...
Source: Kennedy Institute of Ethics Journal - April 8, 2024 Category: Medical Ethics Authors: Savannah Pearlman Source Type: research
Preventive effects of crocin, a natural compound from saffron, against nicotine ‑induced oxidative stress and neurobehavioral disturbances
In this study, we explore the neuroprotective effects of crocin, a bioactive agent commonly found in saffron - a spice derived from the flower of Crocus sativus - using a rat model. The dose‑dependent effects of crocin were evaluated in nicotine‑induced neurodegeneration and compared with a control group. Neurobehavioral changes, assessed through the elevated plus maze, the open field test, the forced swim test, and the Morris water maze, as well as oxidative stress in the hippocampus, were evaluated. Interestingly, nicotine administration resulted in depression, anxiety, and abnormal motor and cognitive functions, whi...
Source: Acta Neurobiologiae Experimentalis - April 8, 2024 Category: Neurology Authors: Majid Motaghinejad Manijeh Motevalian Antoni Sureda Source Type: research
Solidarity Over Charity: Mutual Aid as a Moral Alternative to Effective Altruism
Kennedy Inst Ethics J. 2023;33(2):167-199. doi: 10.1353/ken.2023.a904082.ABSTRACTEffective Altruism is a popular social movement that encourages individuals to donate to organizations that effectively address humanity's most severe poverty. However, because Effective Altruists are committed to doing the most good in the most effective ways, they often argue that it is wrong to help those nearest to you. In this article, I target a major subset of Effective Altruists who consider it a moral obligation to do the most good possible. Call these Obligation-Oriented Effective Altruists (OOEAs), and their movement Obligation-Orie...
Source: Kennedy Institute of Ethics Journal - April 8, 2024 Category: Medical Ethics Authors: Savannah Pearlman Source Type: research
Preventive effects of crocin, a natural compound from saffron, against nicotine ‑induced oxidative stress and neurobehavioral disturbances
In this study, we explore the neuroprotective effects of crocin, a bioactive agent commonly found in saffron - a spice derived from the flower of Crocus sativus - using a rat model. The dose‑dependent effects of crocin were evaluated in nicotine‑induced neurodegeneration and compared with a control group. Neurobehavioral changes, assessed through the elevated plus maze, the open field test, the forced swim test, and the Morris water maze, as well as oxidative stress in the hippocampus, were evaluated. Interestingly, nicotine administration resulted in depression, anxiety, and abnormal motor and cognitive functions, whi...
Source: Acta Neurobiologiae Experimentalis - April 8, 2024 Category: Neurology Authors: Majid Motaghinejad Manijeh Motevalian Antoni Sureda Source Type: research
Solidarity Over Charity: Mutual Aid as a Moral Alternative to Effective Altruism
Kennedy Inst Ethics J. 2023;33(2):167-199. doi: 10.1353/ken.2023.a904082.ABSTRACTEffective Altruism is a popular social movement that encourages individuals to donate to organizations that effectively address humanity's most severe poverty. However, because Effective Altruists are committed to doing the most good in the most effective ways, they often argue that it is wrong to help those nearest to you. In this article, I target a major subset of Effective Altruists who consider it a moral obligation to do the most good possible. Call these Obligation-Oriented Effective Altruists (OOEAs), and their movement Obligation-Orie...
Source: Kennedy Institute of Ethics Journal - April 8, 2024 Category: Medical Ethics Authors: Savannah Pearlman Source Type: research
Preventive effects of crocin, a natural compound from saffron, against nicotine ‑induced oxidative stress and neurobehavioral disturbances
In this study, we explore the neuroprotective effects of crocin, a bioactive agent commonly found in saffron - a spice derived from the flower of Crocus sativus - using a rat model. The dose‑dependent effects of crocin were evaluated in nicotine‑induced neurodegeneration and compared with a control group. Neurobehavioral changes, assessed through the elevated plus maze, the open field test, the forced swim test, and the Morris water maze, as well as oxidative stress in the hippocampus, were evaluated. Interestingly, nicotine administration resulted in depression, anxiety, and abnormal motor and cognitive functions, whi...
Source: Acta Neurobiologiae Experimentalis - April 8, 2024 Category: Neurology Authors: Majid Motaghinejad Manijeh Motevalian Antoni Sureda Source Type: research
Solidarity Over Charity: Mutual Aid as a Moral Alternative to Effective Altruism
Kennedy Inst Ethics J. 2023;33(2):167-199. doi: 10.1353/ken.2023.a904082.ABSTRACTEffective Altruism is a popular social movement that encourages individuals to donate to organizations that effectively address humanity's most severe poverty. However, because Effective Altruists are committed to doing the most good in the most effective ways, they often argue that it is wrong to help those nearest to you. In this article, I target a major subset of Effective Altruists who consider it a moral obligation to do the most good possible. Call these Obligation-Oriented Effective Altruists (OOEAs), and their movement Obligation-Orie...
Source: Kennedy Institute of Ethics Journal - April 8, 2024 Category: Medical Ethics Authors: Savannah Pearlman Source Type: research
Preventive effects of crocin, a natural compound from saffron, against nicotine ‑induced oxidative stress and neurobehavioral disturbances
In this study, we explore the neuroprotective effects of crocin, a bioactive agent commonly found in saffron - a spice derived from the flower of Crocus sativus - using a rat model. The dose‑dependent effects of crocin were evaluated in nicotine‑induced neurodegeneration and compared with a control group. Neurobehavioral changes, assessed through the elevated plus maze, the open field test, the forced swim test, and the Morris water maze, as well as oxidative stress in the hippocampus, were evaluated. Interestingly, nicotine administration resulted in depression, anxiety, and abnormal motor and cognitive functions, whi...
Source: Acta Neurobiologiae Experimentalis - April 8, 2024 Category: Neurology Authors: Majid Motaghinejad Manijeh Motevalian Antoni Sureda Source Type: research
Solidarity Over Charity: Mutual Aid as a Moral Alternative to Effective Altruism
Kennedy Inst Ethics J. 2023;33(2):167-199. doi: 10.1353/ken.2023.a904082.ABSTRACTEffective Altruism is a popular social movement that encourages individuals to donate to organizations that effectively address humanity's most severe poverty. However, because Effective Altruists are committed to doing the most good in the most effective ways, they often argue that it is wrong to help those nearest to you. In this article, I target a major subset of Effective Altruists who consider it a moral obligation to do the most good possible. Call these Obligation-Oriented Effective Altruists (OOEAs), and their movement Obligation-Orie...
Source: Kennedy Institute of Ethics Journal - April 8, 2024 Category: Medical Ethics Authors: Savannah Pearlman Source Type: research
Preventive effects of crocin, a natural compound from saffron, against nicotine ‑induced oxidative stress and neurobehavioral disturbances
In this study, we explore the neuroprotective effects of crocin, a bioactive agent commonly found in saffron - a spice derived from the flower of Crocus sativus - using a rat model. The dose‑dependent effects of crocin were evaluated in nicotine‑induced neurodegeneration and compared with a control group. Neurobehavioral changes, assessed through the elevated plus maze, the open field test, the forced swim test, and the Morris water maze, as well as oxidative stress in the hippocampus, were evaluated. Interestingly, nicotine administration resulted in depression, anxiety, and abnormal motor and cognitive functions, whi...
Source: Acta Neurobiologiae Experimentalis - April 8, 2024 Category: Neurology Authors: Majid Motaghinejad Manijeh Motevalian Antoni Sureda Source Type: research
Solidarity Over Charity: Mutual Aid as a Moral Alternative to Effective Altruism
Kennedy Inst Ethics J. 2023;33(2):167-199. doi: 10.1353/ken.2023.a904082.ABSTRACTEffective Altruism is a popular social movement that encourages individuals to donate to organizations that effectively address humanity's most severe poverty. However, because Effective Altruists are committed to doing the most good in the most effective ways, they often argue that it is wrong to help those nearest to you. In this article, I target a major subset of Effective Altruists who consider it a moral obligation to do the most good possible. Call these Obligation-Oriented Effective Altruists (OOEAs), and their movement Obligation-Orie...
Source: Kennedy Institute of Ethics Journal - April 8, 2024 Category: Medical Ethics Authors: Savannah Pearlman Source Type: research
Preventive effects of crocin, a natural compound from saffron, against nicotine ‑induced oxidative stress and neurobehavioral disturbances
In this study, we explore the neuroprotective effects of crocin, a bioactive agent commonly found in saffron - a spice derived from the flower of Crocus sativus - using a rat model. The dose‑dependent effects of crocin were evaluated in nicotine‑induced neurodegeneration and compared with a control group. Neurobehavioral changes, assessed through the elevated plus maze, the open field test, the forced swim test, and the Morris water maze, as well as oxidative stress in the hippocampus, were evaluated. Interestingly, nicotine administration resulted in depression, anxiety, and abnormal motor and cognitive functions, whi...
Source: Acta Neurobiologiae Experimentalis - April 8, 2024 Category: Neurology Authors: Majid Motaghinejad Manijeh Motevalian Antoni Sureda Source Type: research
