Preparation of Zn/Zr-MOFs by microwave-assisted ball milling and adsorption of lomefloxacin hydrochloride and levofloxacin hydrochloride in wastewater
Environ Res. 2024 Apr 20:118941. doi: 10.1016/j.envres.2024.118941. Online ahead of print.ABSTRACTThe Zn/Zr-MOFs were synthesized via microwave-assisted ball milling and subsequently characterized using Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), and scanning electron microscopy (SEM). The thermal stability of the Zn/Zr-MOFs was evaluated through thermogravimetry (TGA). The results demonstrated the exceptional adsorption properties of the Zn/Zr-MOFs towards Lomefloxacin hydrochloride and Levofloxacin hydrochloride. At a concentration of 30 ppm for Lomefloxacin hydrochloride, the addition of 30...
Source: Environmental Research - April 22, 2024 Category: Environmental Health Authors: Fuhua Wei Jie Gong Qinhui Ren Xiang Yu Yan Wang Hongliang Chen Zhao Liang Source Type: research
Molecular epidemiological and clinical infection characteristics analysis of Ralstonia
ConclusionWe established a sequence typing system with a relatively fine resolution and the PCR assay is a faster and more sensitive method for clinical identification ofRalstonia pickettii. ST9 is the most common sequence types ofRalstonia pickettii. The most common clinical characteristics ofRalstonia pickettii infected patients were cough, sputum, shortness of breath and pulmonary rales. (Source: European Journal of Clinical Microbiology and Infectious Diseases)
Source: European Journal of Clinical Microbiology and Infectious Diseases - April 19, 2024 Category: Microbiology Source Type: research
Developmental stage and infection status may affect drug distribution in the prostate of rats
Xenobiotica. 2024 Apr 18:1-13. doi: 10.1080/00498254.2024.2343892. Online ahead of print.ABSTRACTProstate inflammation is often treated with drugs which are ineffective. Antibacterial agents fail to reach the prostate epithelium, and the blood-prostate barrier (BPB) may affect the drug transport process. Factors affecting drug efficacy remain unclear.Rats were categorized into groups A and B, corresponding to adulthood and puberty, respectively. Group C included the model of chronic prostate infection. Dialysates of levofloxacin and cefradine were collected from the prostate gland and jugular vein and evaluated. Pharmacoki...
Source: Xenobiotica - April 18, 2024 Category: Research Authors: Ziyang Xu Lianzhan Sun Chang Yin Handa Wang Xue Wang Yunyun Yang Zhuo Wang Source Type: research
Developmental stage and infection status may affect drug distribution in the prostate of rats
Xenobiotica. 2024 Apr 18:1-13. doi: 10.1080/00498254.2024.2343892. Online ahead of print.ABSTRACTProstate inflammation is often treated with drugs which are ineffective. Antibacterial agents fail to reach the prostate epithelium, and the blood-prostate barrier (BPB) may affect the drug transport process. Factors affecting drug efficacy remain unclear.Rats were categorized into groups A and B, corresponding to adulthood and puberty, respectively. Group C included the model of chronic prostate infection. Dialysates of levofloxacin and cefradine were collected from the prostate gland and jugular vein and evaluated. Pharmacoki...
Source: Xenobiotica - April 18, 2024 Category: Research Authors: Ziyang Xu Lianzhan Sun Chang Yin Handa Wang Xue Wang Yunyun Yang Zhuo Wang Source Type: research
Viruses, Vol. 16, Pages 627: Trends in and Risk Factors for Drug Resistance in Mycobacterium tuberculosis in HIV-Infected Patients
Zhaoqin Zhu
Yinzhong Shen
Trends in and risk factors for drug resistance in Mycobacterium tuberculosis (M. tuberculosis) in human immunodeficiency virus (HIV)-infected patients with active tuberculosis were analyzed. The clinical data of M. tuberculosis and HIV-coinfected patients treated at the Shanghai Public Health Clinical Center between 2010 and 2022 were collected. The diagnosis of tuberculosis was confirmed by solid or liquid culture. The phenotypic drug susceptibility test was carried out via the proportional method, and the resistance to first-line and second-line drugs was analyzed. Logistic regression an...
Source: Viruses - April 18, 2024 Category: Virology Authors: Xiaoqin Le Xueqin Qian Li Liu Jianjun Sun Wei Song Tangkai Qi Zhenyan Wang Yang Tang Shuibao Xu Junyang Yang Jiangrong Wang Jun Chen Renfang Zhang Zhaoqin Zhu Yinzhong Shen Tags: Article Source Type: research
Challenges in the treatment of pediatric Mycoplasma pneumoniae pneumonia
Conclusion: This report summarizes the clinical significance of macrolide-resistant and refractory MP pneumonia and discusses the efficacy and safety of alternative drugs, with a stepwise approach to the management of MP pneumonia recommended from the viewpoint of clinical practice.What is Known:•Although MP pneumonia is usually a benign self-limited infection with response macrolides as first line therapy,severe life-threatening cases may develop if additional treatment strategies are not effectively implemented.•Macrolide-resistant and refractory MP pneumonia are two conditions that may complicate the clinical cour...
Source: European Journal of Pediatrics - April 18, 2024 Category: Pediatrics Source Type: research
Oral Antibiotics vs IV and Oral Antibiotics for Uncomplicated Appendicitis
This secondary analysis of a randomized clinical trial assesses the 3-year clinical outcomes of oral moxifloxacin vs combined intravenous ertapenem plus oral levofloxacin and metronidazole in patients with uncomplicated acute appendicitis. (Source: JAMA Surgery)
Source: JAMA Surgery - April 17, 2024 Category: Sports Medicine Source Type: research
Emerging threats of high biofilm formation and antibiotic resistance in clinical methicillin-resistant Staphylococcus aureus (MRSA) isolates from Pakistan
CONCLUSIONS: Clinical MRSA strains exhibit a substantial potential for biofilm formation, contributing to a resistant phenotype. Routine antibiotic testing in clinical settings that overlook the biofilm aspect may lead to the failure of empiric antibiotic therapy.PMID:38614413 | DOI:10.1016/j.meegid.2024.105592 (Source: Infection, Genetics and Evolution)
Source: Infection, Genetics and Evolution - April 13, 2024 Category: Genetics & Stem Cells Authors: Asad Ali Saba Riaz Source Type: research
Emerging threats of high biofilm formation and antibiotic resistance in clinical methicillin-resistant Staphylococcus aureus (MRSA) isolates from Pakistan
CONCLUSIONS: Clinical MRSA strains exhibit a substantial potential for biofilm formation, contributing to a resistant phenotype. Routine antibiotic testing in clinical settings that overlook the biofilm aspect may lead to the failure of empiric antibiotic therapy.PMID:38614413 | DOI:10.1016/j.meegid.2024.105592 (Source: Infection, Genetics and Evolution)
Source: Infection, Genetics and Evolution - April 13, 2024 Category: Genetics & Stem Cells Authors: Asad Ali Saba Riaz Source Type: research
Emerging threats of high biofilm formation and antibiotic resistance in clinical methicillin-resistant Staphylococcus aureus (MRSA) isolates from Pakistan
CONCLUSIONS: Clinical MRSA strains exhibit a substantial potential for biofilm formation, contributing to a resistant phenotype. Routine antibiotic testing in clinical settings that overlook the biofilm aspect may lead to the failure of empiric antibiotic therapy.PMID:38614413 | DOI:10.1016/j.meegid.2024.105592 (Source: Infection, Genetics and Evolution)
Source: Infection, Genetics and Evolution - April 13, 2024 Category: Genetics & Stem Cells Authors: Asad Ali Saba Riaz Source Type: research
Emerging threats of high biofilm formation and antibiotic resistance in clinical methicillin-resistant Staphylococcus aureus (MRSA) isolates from Pakistan
CONCLUSIONS: Clinical MRSA strains exhibit a substantial potential for biofilm formation, contributing to a resistant phenotype. Routine antibiotic testing in clinical settings that overlook the biofilm aspect may lead to the failure of empiric antibiotic therapy.PMID:38614413 | DOI:10.1016/j.meegid.2024.105592 (Source: Infection, Genetics and Evolution)
Source: Infection, Genetics and Evolution - April 13, 2024 Category: Genetics & Stem Cells Authors: Asad Ali Saba Riaz Source Type: research
Periprosthetic bacterial and fugal infection after total knee arthroplasty with one-stage debridement: a case report
ConclusionsIn addition to the case study, we provide an analysis of the diagnosis and treatment of fungal infection after arthroplasty, especially the efficacy of debridement, antibiotics, and implant retention for a short-term outcome. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - April 13, 2024 Category: General Medicine Source Type: research
Effects of Rifampicin Plus Levofloxacin or Isoniazid on Immune Function of Patients with Pulmonary Tuberculosis
CONCLUSIONS: Compared with rifampicin + isoniazid, rifampicin + levofloxacin had a better clinical effect in the treatment of pulmonary TB and could effectively regulate patients' immune functions and inhibit inflammatory reactions. The current research team recommends that rifampicin + levofloxacin become the preferred treatment for pulmonary TB in the absence of a drug allergy.PMID:38607224 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 12, 2024 Category: Complementary Medicine Authors: Feng Lv Nan Tang Source Type: research
Effects of Rifampicin Plus Levofloxacin or Isoniazid on Immune Function of Patients with Pulmonary Tuberculosis
CONCLUSIONS: Compared with rifampicin + isoniazid, rifampicin + levofloxacin had a better clinical effect in the treatment of pulmonary TB and could effectively regulate patients' immune functions and inhibit inflammatory reactions. The current research team recommends that rifampicin + levofloxacin become the preferred treatment for pulmonary TB in the absence of a drug allergy.PMID:38607224 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 12, 2024 Category: Complementary Medicine Authors: Feng Lv Nan Tang Source Type: research
Effects of Rifampicin Plus Levofloxacin or Isoniazid on Immune Function of Patients with Pulmonary Tuberculosis
CONCLUSIONS: Compared with rifampicin + isoniazid, rifampicin + levofloxacin had a better clinical effect in the treatment of pulmonary TB and could effectively regulate patients' immune functions and inhibit inflammatory reactions. The current research team recommends that rifampicin + levofloxacin become the preferred treatment for pulmonary TB in the absence of a drug allergy.PMID:38607224 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 12, 2024 Category: Complementary Medicine Authors: Feng Lv Nan Tang Source Type: research
