Challenges in the treatment of pediatric Mycoplasma pneumoniae pneumonia

Conclusion:  This report summarizes the clinical significance of macrolide-resistant and refractory MP pneumonia and discusses the efficacy and safety of alternative drugs, with a stepwise approach to the management of MP pneumonia recommended from the viewpoint of clinical practice.What is Known:•Although MP pneumonia is usually a benign self-limited infection with response macrolides as first line therapy,severe life-threatening cases may develop if additional treatment strategies are not effectively implemented.•Macrolide-resistant and refractory MP pneumonia are two conditions that may complicate the clinical course ofMP pneumonia, increasing the risk for exacerbation and even death.What is New:•This report summarizes the clinical relevance of macrolide-resistant and refractory MP pneumonia and discussesthe efficacy and safety of alternative drug therapies.•A practical stepwise approach to the management of MP pneumonia is developed based on a comprehensiveanalysis of existing evidence and expert opinion.
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research