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Antibiotic Shows Promise for Major Depression Antibiotic Shows Promise for Major Depression
Minocycline, a broad-spectrum antibiotic frequently used to treat acne, may have utility as an adjunct for treating depression, especially by improving global functioning and quality of life.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 12, 2017 Category: Consumer Health News Tags: Psychiatry News Source Type: news

Ximino (Minocycline Hydrochloride) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - June 21, 2017 Category: Drugs & Pharmacology Source Type: news

PodMed: A Medical News Roundup From Johns Hopkins (with audio)
(MedPage Today) -- This week's topics include treating resistant hepatitis C infection, a new regimen for breast cancer, evolution of non-small cell lung cancer, and minocycline for MS (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - June 3, 2017 Category: Gastroenterology Source Type: news

Old Antibiotic May Slow Conversion From CIS to MS Old Antibiotic May Slow Conversion From CIS to MS
Treatment with minocycline met the randomized controlled trial's primary endpoint, decreasing conversion vs placebo within 6 months, but between-group differences weren't sustained at 24 months.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 1, 2017 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Minocycline Might Help Prevent Progression to Multiple Sclerosis (FREE)
By the Editors The antibiotic minocycline might help prevent progression to multiple sclerosis in patients with an isolated demyelinating event, a New England Journal of … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - June 1, 2017 Category: Primary Care Source Type: news

Common acne medicine reduces risk of multiple sclerosis, Calgary researchers find
Millions of people already take minocycline to treat acne, but University of Calgary researchers have found the inexpensive antibiotic also helps to control multiple sclerosis. (Source: CBC | Health)
Source: CBC | Health - May 31, 2017 Category: Consumer Health News Tags: News/Canada/Calgary Source Type: news

Arestin (Minocycline Hydrochloride Microspheres) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - May 22, 2017 Category: Drugs & Pharmacology Source Type: news

Minolira (Minocycline Hydrochloride Extended-Release Tablets) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - May 19, 2017 Category: Drugs & Pharmacology Source Type: news

What Are Options for Acne Treatment?
Discussion Acne vulgaris or acne is a problem of the pilosebaceous follicle. It occurs most prominently where sebaceous glands are abundant especially the face, neck, and upper back. Sebum production increases because of androgens. Keratin and sebum clog the pores of the pilosebaceous unit causing hyperkeratosis (clogged pilosebaceous unit = clogged pores = comedomes). Propionibacterium acnes, a gram-negative anaerobe, multiplies in the sebaceous unit causing an inflammatory reaction resulting in moderate or severe acne. Skin lesions include: Comedomal acne has comedomes White heads = closed comedomes Black heads = open...
Source: PediatricEducation.org - January 16, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Minocin Injection (Minocycline Inj) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 15, 2016 Category: Drugs & Pharmacology Source Type: news

Minocin (Minocycline Hydrochloride Oral Suspension) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 15, 2016 Category: Drugs & Pharmacology Source Type: news

Catheter impregnation, coating or bonding for reducing central venous catheter-related infections in adults
This Cochrane Review informed a practice changing update on Dynamed Plus. It found that antimicrobial coatings that appear to reduce risk of central venous catheter-related bloodstream infection include minocycline-rifampicin, chlorhexidine silver sulfadiazine, silver, and heparin, but antimicrobial coatings do not appear to reduce risk of sepsis or mortality (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - December 2, 2016 Category: Consumer Health News Source Type: news

minocycline (Dynacin, Minocin)
Title: minocycline (Dynacin, Minocin)Category: MedicationsCreated: 3/2/2005 12:00:00 AMLast Editorial Review: 9/14/2016 12:00:00 AM (Source: MedicineNet Skin General)
Source: MedicineNet Skin General - September 14, 2016 Category: Dermatology Source Type: news

Minocin Capsules (Minocycline) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 8, 2016 Category: Drugs & Pharmacology Source Type: news

BioPharmX begins patient enrolment in Phase IIb OPAL study of BPX-01 to treat acne vulgaris
US-based pharmaceutical company BioPharmX has enrolled the first patient in its Phase IIb tOPicAL Minocycline Gel (OPAL) clinical trial of BPX-01 to treat acne vulgaris. (Source: Drug Development Technology)
Source: Drug Development Technology - August 24, 2016 Category: Pharmaceuticals Source Type: news

MassDevice.com +5 | The top 5 medtech stories for June 22, 2016
Say hello to MassDevice +5, a bite-sized view of the top five medtech stories of the day. This feature of MassDevice.com’s coverage highlights our 5 biggest and most influential stories from the day’s news to make sure you’re up to date on the headlines that continue to shape the medical device industry. Get this in your inbox everyday by subscribing to our newsletters.   5. J&J investor relations veep Mehrotra retires, Wolk steps up Johnson & Johnson said today its 10-year vice president of investor relations Louise Mehrotra will retire, effective January 2017, to be replaced by Joseph Wol...
Source: Mass Device - June 22, 2016 Category: Medical Equipment Authors: MassDevice Tags: News Well Plus 5 Source Type: news

FDA warns Medtronic’s Tyrx on anti-bacterial envelopes
The FDA sent a warning letter earlier this month to Medtronic (NYSE:MDT) subsidiary Tyrx over problems with its process validation and quality systems. The Tyrx envelopes are designed to elute a pair of anti-microbial drugs, minocycline and rifampin, for 7 days before dissolving over a period of roughly 9 weeks. They’re cleared for use with pacemakers, implantable cardioverter-defibrillators, cardiac resynchronization therapy devices, deep-brain stimulators, sacral nerve stimulators, spinal cord stimulators and vagus nerve stimulators. Tyrx, which Medtronic acquired for $160 million in Januar...
Source: Mass Device - June 22, 2016 Category: Medical Equipment Authors: Brad Perriello Tags: Regulatory/Compliance Surgical Medtronic TYRX Inc. Warning Letter Source Type: news

Adjunctive minocycline microspheres
The aim of this study was to compare the effects of adjunctive Minocycline HCl Microspheres (Arestin) with debridement alone on the levels of 40 subgingival bacterial species in the treatment of peri-implantitis. Reseachers recruited 208 subjects (from 11 centers in the USA) with at least 1 implant with peri-implantitis and randomized to receive either mechanical debridement alone (n=104) or mechanical debridement followed by Arestin (1 mg) (n=104) at baseline and day 90. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 20, 2016 Category: Science Source Type: news

Meibomian Gland Dysfunction: Poor Evidence for Oral Antibiotics Meibomian Gland Dysfunction: Poor Evidence for Oral Antibiotics
More research is needed to define the role of doxycycline, minocycline, and azithromycin in this difficult-to-treat condition. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 29, 2015 Category: Consumer Health News Tags: Ophthalmology News Source Type: news

Old Drug Has New Promise in MSOld Drug Has New Promise in MS
Minocycline, an antibiotic that has been around for decades, reduced the risk for progression from clinically isolated syndrome to definite multiple sclerosis in a new study. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - October 14, 2015 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Tried-and-True Antibiotic May Block Conversion to MS (CME/CE)
(MedPage Today) -- Minocycline seemed to reduce progression to multiple sclerosis after first demyelinating event (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - October 10, 2015 Category: Neurology Source Type: news

FDA clears Medtronic’s Tyrx envelope for DBS devices
Medtronic (NYSE:MDT) said today that it’s launching its Tyrx surgical envelope in the U.S. for use with deep-brain stimulation devices, after it won 510(k) clearance from the FDA for use of the infection-fighting envelope with implantable neurostimulators. Fridley, Minn.-based Medtronic said it’s planning to make the Tyrx device, acquired for $160 million in January 2014, available for other neurostim indications “in the coming months.” The device is designed to elute a pair of anti-microbial drugs, minocycline and rifampin, for 7 days. The envelope is designed to then dissolve over a...
Source: Mass Device - October 8, 2015 Category: Medical Equipment Authors: Brad Perriello Tags: Cardiovascular Food & Drug Administration (FDA) Neuromodulation/Neurostimulation Regulatory/Compliance Surgical Medtronic TYRX Inc. Source Type: news

What Are Common Drug Eruptions in Children?
Patient Presentation A 4-year-old female came to clinic because of a rash for 24 hours. The pruritic rash began the evening before with a few red spots on her trunk. She had slept well, but this morning they were spreading and enlarging in size on her trunk, neck and extremities and did not seem to come and go. She also had a fever and her mother thought that she wasn’t moving as well and seemed to be sore. The patient had been started on cefaclor 9 days earlier for an ear infection and upper respiratory tract infection symptoms. She had previously taken penicillins and cephalosporin antibiotics without any problems...
Source: PediatricEducation.org - July 27, 2015 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Medical device companies boost guarantees to hospitals
Medical device companies are reportedly boosting their guarantees to hospital customers, seeking to bolster flagging sales growth and downward price pressure, offering to compensate them if their devices fail to perform. Medtronic (NYSE:MDT), Johnson & Johnson (NYSE:JNJ) and St. Jude Medical (NYSE:STJ) are among the 1st to provide the newer guarantees, some of which offer to share in the cost of follow-up treatment tied to their heart devices, company executives told Reuters. Orthopedic device companies are also mulling similar guarantees for their hip and knee implants. But even that may not be eno...
Source: Mass Device - July 8, 2015 Category: Medical Equipment Authors: Brad Perriello Tags: Business/Financial News BioSense Webster Inc. Ethicon Inc. Johnson & Johnson medtronic St. Jude Medical Source Type: news

Minocycline Effective for Erythema Nodosum LeprosumMinocycline Effective for Erythema Nodosum Leprosum
Minocycline is effective for treating recurrent and chronic erythema nodosum leprosum (ENL), according to a pilot study in 10 patients with multibacillary leprosy. Reuters Health Information (Source: Medscape Dermatology Headlines)
Source: Medscape Dermatology Headlines - April 30, 2015 Category: Dermatology Tags: Dermatology News Source Type: news

Minocin (Minocycline Hydrochloride Oral Suspension) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - April 14, 2015 Category: Drugs & Pharmacology Source Type: news

Hovione Files Milestone IND for Topical Zit Zapper
Minocycline gel is a novel formulation to administer topically using a new patented crystalline base form of minocycline (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - December 9, 2014 Category: Pharmaceuticals Source Type: news

minocycline (Dynacin, Minocin)
Title: minocycline (Dynacin, Minocin)Category: MedicationsCreated: 3/2/2005 12:00:00 AMLast Editorial Review: 10/3/2014 12:00:00 AM (Source: MedicineNet Skin General)
Source: MedicineNet Skin General - October 3, 2014 Category: Dermatology Source Type: news

The skin foam that can kill acne reduces number by 72 per cent in three months
FMX101 contains minocycline, an antibiotic long used to treat the condition but which in tablet form can have side effects including vertigo and diarrhoea. (Source: the Mail online | Health)
Source: the Mail online | Health - September 30, 2014 Category: Consumer Health News Source Type: news

'Acne medication left me partially blind': Mother prescribed common antibiotics can no longer drive due to blurred vision
Rachel Yeo, 26, from Penarth, Wales, developed high pressure within her skull after taking Minocycline - this caused severe headaches and vision problems. (Source: the Mail online | Health)
Source: the Mail online | Health - January 13, 2014 Category: Consumer Health News Source Type: news

Treatment of Infections Due to Resistant Staphylococcus aureus
This chapter reviews data on the treatment of infections caused by drug-resistant Staphylococcus aureus, particularly methicillin-resistant S. aureus (MRSA). This review covers findings reported in the English language medical literature up to January of 2013. Despite the emergence of resistant and multidrug-resistant S. aureus, we have seven effective drugs in clinical use for which little resistance has been observed: vancomycin, quinupristin–dalfopristin, linezolid, tigecycline, telavancin, ceftaroline, and daptomycin. However, vancomycin is less effective for infections with MRSA isolates that have a higher MIC w...
Source: Springer protocols feed by Microbiology - October 6, 2013 Category: Microbiology Source Type: news

Help Prevent Intravascular Devices-Related Bloodstream Infections With Minocycline
This method uses a 50:50 THF:water extraction solvent for the preparation of standards and samples.By R. L. Steffen, A. K. Wilson, D.G. Cuttell, M.S. Medrano, L.R. Brewster, and A. Hoffa (Source: Pharmaceutical Online News)
Source: Pharmaceutical Online News - August 23, 2013 Category: Pharmaceuticals Source Type: news

Newly Published Research Confirms the Efficacy of the Drug Combination...
The completion of preclinical studies demonstrating the neuro-protective and neuro-regenerative properties of minocycline together with NAC bolsters support for human clinical trials. Neurological...(PRWeb July 10, 2013)Read the full story at http://www.prweb.com/releases/2013/7/prweb10825205.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - July 13, 2013 Category: Pharmaceuticals Source Type: news

Antibiotic Helps Fragile X Kids (CME/CE)
(MedPage Today) -- Treatment with minocycline led to significant, though limited, improvements in children with fragile X syndrome, a randomized study found. (Source: MedPage Today Pediatrics)
Source: MedPage Today Pediatrics - April 11, 2013 Category: Pediatrics Source Type: news

Minocycline Show Benefits In Children With Inherited Cause Of Intellectual Disability And Autism
The antibiotic drug minocycline yields "modest" but meaningful improvements in functioning and mood for children with fragile X syndrome (FXS), reports a study in the April Journal of Developmental & Behavioral Pediatrics, the official journal of the Society for Developmental and Behavioral Pediatrics. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health. Three months of treatment with minocycline in children with FXS resulted in greater overall improvement than placebo treatment, according to the study by Dr Mary Jacena S... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 10, 2013 Category: Consumer Health News Tags: Autism Source Type: news

Study investigates minocycline pleurodesis for primary spontaneous pneumothorax
Source: Lancet Area: News According to the results of an open-label RCT conducted in Taiwan, the use of minocycline pleurodesis after simple aspiration is safe and more effective than simple aspiration and drainage only in the treatment for primary spontaneous pneumothorax.   The authors note that simple aspiration and drainage is a standard initial treatment for primary spontaneous pneumothorax. However there is a high rate of recurrence, and they therefore sought to investigate the adjunctive use of minocycline pleurodesis in this setting.  The study, conducted at two hospitals in Taiwan, included 214 pati...
Source: NeLM - News - February 18, 2013 Category: Drugs & Pharmacology Source Type: news

NICE publishes QIPP Medicines Management document
Source: NICE Area: News NICE has published an evidence based document summarising medicines management options for local implementation on identified topics supporting the QIPP medicines use and procurement work stream. The document, which is not formal NICE guidance, covers the following identified topics:   . Laxatives . Renin-angiotensin system drugs . Lipid modifying drugs including ezetimibe . Omega-3 fatty acid supplements . High dose inhaled corticosteroids in asthma . Hypnotics . Low dose antipsychotics in people with dementia . First-choice antidepres...
Source: NeLM - News - February 1, 2013 Category: Drugs & Pharmacology Source Type: news

Minor Mutations Can Lead To Big Improvements In Antibiotic Resistance
Rice University scientists have found that mutations of small effect can turn out to be game changers in the bacterial fight against antibiotic drugs. The discovery came during an exhaustive, three-year effort to create a mathematical model that could accurately predict how specific mutations allow bacteria like E. coli to adapt to antibiotics like minocycline. The findings are detailed in a study in the Proceedings of the National Academy of Sciences... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 11, 2013 Category: Consumer Health News Tags: MRSA / Drug Resistance Source Type: news

Drug resistance in E. coli: 'Baby steps' can pay off big
Scientists have found that mutations of seemingly small consequence can turn out to be game changers in the bacterial fight against antibiotic drugs. The discovery came during an exhaustive, three-year effort to create a mathematical model that could accurately predict how specific mutations would allow E. coli to ward off attacks by the antibiotic minocycline. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 9, 2013 Category: Science Source Type: news

Drug resistance: 'Baby steps' can pay off big
(Rice University) Rice University scientists have found that mutations of seemingly small consequence can turn out to be game changers in the bacterial fight against antibiotic drugs. The discovery came during an exhaustive, three-year effort to create a mathematical model that could accurately predict how specific mutations would allow E. coli to ward off attacks by the antibiotic minocycline. The findings are detailed in a Dec. 10 study in the Proceedings of the National Academy of Sciences. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 9, 2013 Category: Global & Universal Source Type: news