Trial from Niger finds village-wide prophylactic antibiotics contained spread of meningitis
(PLOS) Distribution of single doses of the oral antibiotic ciprofloxacin to residents of rural villages in the African meningitis belt reduced the number of meningitis cases during a 2017 meningitis epidemic, according to a new study in PLOS Medicine by Matthew Coldiron and colleagues from Epicentre and M é decins Sans Fronti è res in France, Switzerland and Niger. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 26, 2018 Category: Infectious Diseases Source Type: news

Rise in Possible Fluoroquinolone-Resistant Shigella Isolates Rise in Possible Fluoroquinolone-Resistant Shigella Isolates
The CDC is seeing an increasing number of Shigella isolates that test within the susceptible range for the fluoroquinolone antibiotic ciprofloxacin but harbor one or more resistance mechanisms.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 7, 2018 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

Cipro HC Otic (Ciprofloxacin Hydrochloride Otic Suspension) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - May 14, 2018 Category: Drugs & Pharmacology Source Type: news

Antibiotics Tied to Higher Kidney Stone Risk
The five antibiotic classes newly linked to kidney stone risk included sulfas (Bactrim, Gantanol); cephalosporins (Keflex); fluoroquinolones (Cipro); nitrofurantoin/methenamine (Macrobid, Hiprex); and broad-spectrum penicillins. (Source: WebMD Health)
Source: WebMD Health - May 11, 2018 Category: Consumer Health News Source Type: news

Otonomy Announces FDA Approval of Otiprio (ciprofloxacin otic suspension) for Acute Otitis Externa
SAN DIEGO, March 02, 2018 (GLOBE NEWSWIRE) -- Otonomy, Inc. (NASDAQ:OTIC), a biopharmaceutical company dedicated to the development of innovative therapeutics for otology, today announced that the U.S. Food and Drug Administration (FDA) has approved... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - March 2, 2018 Category: Drugs & Pharmacology Source Type: news

Cipro, Cipro XR (ciprofloxacin) Antibiotic Side Effects
Title: Cipro, Cipro XR (ciprofloxacin) Antibiotic Side EffectsCategory: MedicationsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 2/26/2018 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - February 26, 2018 Category: Drugs & Pharmacology Source Type: news

Bactrim vs. Cipro
Title: Bactrim vs. CiproCategory: MedicationsCreated: 2/16/2018 12:00:00 AMLast Editorial Review: 2/16/2018 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - February 16, 2018 Category: Drugs & Pharmacology Source Type: news

High levels of antibiotic resistance found worldwide, new data show
BANGKOK 29 January 2018 – The World Health Organization’s first release of surveillance data on antibiotic resistance reveals high levels of resistance to a number of serious bacterial infections in both high- and low-income countries. WHO’s new Global Antimicrobial Surveillance System (known as GLASS) reveals widespread occurrence of antibiotic resistance among 500 000 people with suspected bacterial infections across 22 countries.  The most commonly reported resistant bacteria were Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, and Streptococcus pneumoniae, followed by Salmo...
Source: WHO EMRO News - January 29, 2018 Category: Middle East Health Source Type: news

FDA Panel Does Not Recommend Cipro Dispersion for Inhalation FDA Panel Does Not Recommend Cipro Dispersion for Inhalation
An FDA panel did not recommend ciprofloxacin dispersion for inhalation for non-cystic fibrosis bronchiectasis in patients with chronic lung infections with Pseudomonas aeruginosa.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 15, 2018 Category: Consumer Health News Tags: Pulmonary Medicine News Source Type: news

Boosting the antibiotic arsenal
(Massachusetts Institute of Technology) MIT researchers have discovered a way to make bacteria more vulnerable to a class of antibiotics known as quinolones, which include ciprofloxacin and are often used to treat infections such as Escherichia coli and Staphylococcus aureus. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 8, 2017 Category: International Medicine & Public Health Source Type: news

Can I Give Cholera Vaccine?
Discussion Cholera is caused by more than 200 serogroups of Vibrio cholerae, a Gram-negative rod that is waterborne. Only two (serogroup O1 which causes about 99% of the cases, and O139) cause disease. There are biotypes of each of these serotypes. The only known hosts are humans. The organism colonizes the epithelial lining of the gut. Cholera toxin is produced by some species and if produced binds to specific receptors on host cells, activating a series of steps which cases massive loss of sodium, potassium, chloride, hydrogen carbonate, and fluids in vomitus and feces. A review of causes of diarrhea can be found here. ...
Source: PediatricEducation.org - November 27, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Otiprio (Ciprofloxacin Otic Suspension) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - October 20, 2017 Category: Drugs & Pharmacology Source Type: news

Cipro vs. Flagyl (Differences between Side Effects and Uses)
Title: Cipro vs. Flagyl (Differences between Side Effects and Uses)Category: MedicationsCreated: 10/3/2017 12:00:00 AMLast Editorial Review: 10/3/2017 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - October 3, 2017 Category: Drugs & Pharmacology Source Type: news

Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine
Growing evidence suggests that microbes can influence the efficacy of cancer therapies. By studying colon cancer models, we found that bacteria can metabolize the chemotherapeutic drug gemcitabine (2',2'-difluorodeoxycytidine) into its inactive form, 2',2'-difluorodeoxyuridine. Metabolism was dependent on the expression of a long isoform of the bacterial enzyme cytidine deaminase (CDDL), seen primarily in Gammaproteobacteria. In a colon cancer mouse model, gemcitabine resistance was induced by intratumor Gammaproteobacteria, dependent on bacterial CDDL expression, and abrogated by cotreatment with the antibiotic ciprofloxa...
Source: ScienceNOW - September 14, 2017 Category: Science Authors: Geller, L. T., Barzily-Rokni, M., Danino, T., Jonas, O. H., Shental, N., Nejman, D., Gavert, N., Zwang, Y., Cooper, Z. A., Shee, K., Thaiss, C. A., Reuben, A., Livny, J., Avraham, R., Frederick, D. T., Ligorio, M., Chatman, K., Johnston, S. E., Mosher, C. Tags: Medicine, Diseases reports Source Type: news

Ciprofloxacin Hydrochloride Tablets (New - Discontinuation)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - September 8, 2017 Category: Drugs & Pharmacology Source Type: news

Aradigm lands NIH grant for inhaled, liposomal products
Aradigm Corp. (NSDQ:ARDM) said today that the National Institute of Allergy and Infectious Diseases and the NIH awarded the company a grant to study the treatment of pulmonary non-tuberculous mycobacteria infections with Aradigm’s inhaled liposomal ciprofloxacin products, Linhaliq and Lipoquin. The two-year grant is worth approximately $972,000, according to the Hayward, Calif.-based company. Get the full story at our sister site, Drug Delivery Business News. The post Aradigm lands NIH grant for inhaled, liposomal products appeared first on MassDevice. (Source: Mass Device)
Source: Mass Device - August 15, 2017 Category: Medical Devices Authors: Sarah Faulkner Tags: Drug-Device Combinations Funding Roundup Pharmaceuticals Respiratory Wall Street Beat Aradigm Corp. Source Type: news

Certain Antibiotics May Increase Risk of Birth Defects
Ciprofloxacin, levofloxacin and other drugs like them should be avoided in pregnancy, a study found. (Source: NYT Health)
Source: NYT Health - July 20, 2017 Category: Consumer Health News Authors: NICHOLAS BAKALAR Tags: Pregnancy and Childbirth Antibiotics Babies and Infants Birth Defects Source Type: news

Toothpaste ingredient linked to antibiotic resistance
Conclusion This study mainly explored why bacterial resistance could be common for both quinolone antibiotics like ciprofloxacin and the antibacterial triclosan. It confirmed previous findings that one cause seems to be bacteria developing mutations in the gyrA gene. In the case of quinolones, the mutation alters the enzyme that they normally bind to. Triclosan resistance is largely because the already-mutant bacteria have boosted stress response pathways, or molecular defences. The main finding of this research was that small triclosan concentrations led to resistant E. coli bacteria becoming the more dominant strains m...
Source: NHS News Feed - July 5, 2017 Category: Consumer Health News Tags: Medication Source Type: news

Rapid Assay Revives Ciprofloxacin Use for Gonorrhea Rapid Assay Revives Ciprofloxacin Use for Gonorrhea
A pharmacogenomics approach identified gonorrhea infections susceptible to ciprofloxacin and allowed physicians to reserve ceftriaxone for resistant cases.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 2, 2017 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

Scientists develop test to identify best treatment for gonorrhea
FINDINGSResearchers from UCLA have developed a laboratory test that helps physicians determine which people with gonorrhea may be more treatable with an antibiotic that has not been recommended since 2007 because of concerns that the resistance to the drug was growing.BACKGROUNDGonorrhea has developed increasing resistance to all current antibiotics. Due to the spread of multi-drug resistant gonorrhea, health authorities have declared it one of the top-three urgent threats to public health.Ciprofloxacin was used to combat the sexually transmitted infection until 2007, when the Centers for Disease Control and Prevention sto...
Source: UCLA Newsroom: Health Sciences - May 23, 2017 Category: Universities & Medical Training Source Type: news

CDC Issues Health Advisory on < i > Shigella < /i >
The CDC has released a Health Alert Network health advisory warning clinicians about emergingShigella strains that show possible reduced susceptibility to ciprofloxacin. (Source: AAFP News)
Source: AAFP News - April 20, 2017 Category: Primary Care Source Type: news

Public Health England (PHE) PGD template for supply of ciprofloxacin (meningoccal disease)
PHE have published this PGD template to support the supply of ciprofloxacin to adults and children for the management of clusters of meningococcal disease, when 2 or more cases are reported in a congregate setting. It is valid from 10 February 2017 until 10 February 2020 (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - February 28, 2017 Category: Consumer Health News Source Type: news

Cat Scratch Disease
Cat scratch disease is an infection transmitted by cat scratches and bites. The lesion is usually small and less than 1 cm in length. It is normally a benign, self-limiting illness lasting for about 6-12 weeks. It is caused by an exposure to bartonella henselae bacteria. Scratches or bites from an infected cat can cause symptoms in people including swollen and draining lymph nodes, fever, fatigue and headache. Swollen, tender, or hard lymph nodes could be confused with a soft tissue tumor. Regional Lymphadenopathy (main clinical feature) These areas of lymph node concentration include cervical nodes, axillary node...
Source: Healthy Living - The Huffington Post - February 2, 2017 Category: Consumer Health News Source Type: news

Teva's Barr Labs Settles Cipro Antitrust Case for $225 Mln Teva's Barr Labs Settles Cipro Antitrust Case for $225 Mln
Teva Pharmaceutical Industries Ltd's Barr Laboratories Inc has reached a $225 million settlement in an antitrust class action that accused the drugmaker of keeping a generic version of Bayer AG's antibiotic ciprofloxacin (Cipro) off the market, court documents showed.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - January 30, 2017 Category: Pathology Tags: Pathology & Lab Medicine News Source Type: news

Teva's Barr Labs settles Cipro antitrust case for $225 million
(Reuters) - Teva Pharmaceutical Industries Ltd's Barr Laboratories Inc has reached a $225 million settlement in an antitrust class action that accused the drugmaker of keeping a generic version of Bayer AG's antibiotic Cipro off the market, court documents showed. (Source: Reuters: Health)
Source: Reuters: Health - January 27, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Proquin XR (Ciprofloxacin Hcl) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 8, 2016 Category: Drugs & Pharmacology Source Type: news

Cetraxal (Ciprofloxacin Otic Solution) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 8, 2016 Category: Drugs & Pharmacology Source Type: news

Cipro I.V. (Ciprofloxacin IV) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 8, 2016 Category: Drugs & Pharmacology Source Type: news

NIAID-supported study examines vulnerability of gonorrhea to older antibiotic drug
(NIH/National Institute of Allergy and Infectious Diseases) A new clinical research study seeks to determine whether a rapid molecular diagnostic test can reliably identify gonorrhea infections that may be treated with a single dose of an older antibiotic, ciprofloxacin. The study will enroll up to 381 men and women diagnosed with untreated Neisseria gonorrhoeae. It is sponsored by the National Institute of Allergy and Infectious Diseases and is being conducted by the NIAID-funded Sexually Transmitted Infections Clinical Trials Group at four sites. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 17, 2016 Category: Infectious Diseases Source Type: news

Ciloxan Ophthalmic Solution (Ciprofloxacin HCL Ophthalmic Solution) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - October 6, 2016 Category: Drugs & Pharmacology Source Type: news

Cheap Drugs May Have Turned This Indian Lake Into A 'Superbug Hotspot'
Centuries ago, Indian princes would bathe in the cool Kazhipally lake in Medak. Now, even the poorest villagers here in India’s baking south point to the barren banks and frothy water and say they avoid going anywhere near it. A short drive from the bustling tech hub of Hyderabad, Medak is the heart of India’s antibiotics manufacturing business: a district of about 2.5 million that has become one of the world’s largest suppliers of cheap drugs to most markets, including the United States. But community activists, researchers and some drug company employees say the presence of more than 300 drug firms, com...
Source: Healthy Living - The Huffington Post - September 29, 2016 Category: Consumer Health News Source Type: news

Ciprodex (Ciprofloxacin and Dexamethasone ) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 21, 2016 Category: Drugs & Pharmacology Source Type: news

Increase in antibiotic-resistant bacteria hinders treatment of kidney infections
The increase in illnesses and deaths linked to medication-resistant bacteria has been well-documented by researchers and received extensive public attention in recent years. Now, UCLA-led research shows how these bacteria are making it more difficult to treat a common but severe kidney infection.Pyelonephritis — infection of the kidney usually caused by E. coli bacteria and which can start as a urinary tract infection — causes fever, back pain and vomiting. About half of people infected require hospitalization. If not treated with effective antibiotics, it can cause sepsis and death.In a UCLA-led study bas...
Source: UCLA Newsroom: Health Sciences - September 16, 2016 Category: Universities & Medical Training Source Type: news

Laboratorios Salvat S.A. and Arbor Pharmaceuticals, LLC Announce the Launch of Otovel (ciprofloxacin 0.3 % and fluocinolone acetonide 0.025 %) Otic Solution
BARCELONA, Spain and ATLANTA, Aug. 29, 2016 /PRNewswire/ -- Laboratorios Salvat S.A. (Salvat) and Arbor Pharmaceuticals, LLC (Arbor) jointly announce the launch of Otovel (ciprofloxacin 0.3 % and fluocinolone acetonide 0.025 %) otic solution, the... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - August 29, 2016 Category: Drugs & Pharmacology Source Type: news

Ciloxan Ophthalmic Ointment (Ciprofloxacin HCl Ophthalmic Ointment) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - August 9, 2016 Category: Drugs & Pharmacology Source Type: news

Cipro (Ciprofloxacin) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - August 8, 2016 Category: Drugs & Pharmacology Source Type: news

Cipro XR (Ciprofloxacin Extended-Release) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - August 8, 2016 Category: Drugs & Pharmacology Source Type: news

Yet Another Warning On Fluoroquinolone Antibiotic Side Effects
Rare but significant and debilitating side effects - tendon rupture, peripheral neuropathy - can occur with fluoroquinolone antibiotics like Avelox or Cipro. The FDA is now warning that some of these side effects can occur together and that use of these drugs should be restricted for most uncomplicated infections. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - August 1, 2016 Category: Pharmaceuticals Authors: David Kroll Source Type: news

FDA Bolsters Warnings About Class of Antibiotics
Fluoroquinolones such as Cipro, Levaquin should be reserved for life-threatening infections (Source: WebMD Health)
Source: WebMD Health - July 26, 2016 Category: Consumer Health News Source Type: news

FDA Updates Fluoroquinolone Labels to Emphasize Risks for Disabling Adverse Events (FREE)
By Amy Orciari Herman Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM The FDA has updated the labels of systemic fluoroquinolones (e.g., ciprofloxacin, levofloxacin) to note that they're associated with numerous serious … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - July 26, 2016 Category: Primary Care Source Type: news

FDA Bolsters Warnings about Class of Antibiotics
Fluoroquinolones such as Cipro, Levaquin should be reserved for life-threatening infections Source: HealthDay Related MedlinePlus Pages: Antibiotics, Drug Safety (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - July 26, 2016 Category: Consumer Health News Source Type: news

FDA Adds Label Warnings on Cipro, Related Drugs
(MedPage Today) -- Strengthens black-box warning on fluoroquinolone antibiotics (Source: MedPage Today Emergency Medicine)
Source: MedPage Today Emergency Medicine - July 26, 2016 Category: Emergency Medicine Source Type: news

Otonomy Announces Assignment of C Code and Pass-Through Payment Status for OTIPRIO(TM)
SAN DIEGO, May 20, 2016 -- (Healthcare Sales & Marketing Network) -- Otonomy, Inc. (OTIC), a biopharmaceutical company focused on the development and commercialization of innovative therapeutics for diseases and disorders of the ear, today announced that t... Biopharmaceuticals, ReimbursementOtonomy, OTIPRIO, ciprofloxacin otic (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - May 20, 2016 Category: Pharmaceuticals Source Type: news

Physicians React to New FDA Warning on Cipro, Similar Drugs
(MedPage Today) -- Experts discuss FDA warning, impact, and other drug choices (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - May 18, 2016 Category: American Health Source Type: news

Otovel (Ciprofloxacin and Fluocinolone Acetonide Otic Solution) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - May 18, 2016 Category: Drugs & Pharmacology Source Type: news

FDA Calls for More Restrictions on Fluoroquinolone Use (FREE)
By Kristin J. Kelley Edited by Susan Sadoughi, MD, and André Sofair, MD, MPH The risks for "disabling and potentially permanent" side effects associated with systemic fluoroquinolone antibacterials (e.g., ciprofloxacin, moxifloxacin) generally outweigh the benefits in patients with … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 15, 2016 Category: Primary Care Source Type: news

D.C. Week: Federal Judge Rules Against ACA Subsidies
(MedPage Today) -- FDA warns that Cipro and similar antibiotics should not be used for uncomplicated infections (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - May 14, 2016 Category: Psychiatry Source Type: news

FDA: Cipro side effects outweigh benefit for some infections
NEW YORK (AP) — The U.S. Food and Drug Administration is ratcheting up its warning about the potential side effects of a type of commonly-prescribed powerful antibiotic often known by the brand name Cipro. (Source: U.S. News - Health)
Source: U.S. News - Health - May 13, 2016 Category: Consumer Health News Source Type: news

FDA: Avoid Cipro, Similar Drugs for Common Infections
(MedPage Today) -- Agency says risks outweigh benefits (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - May 12, 2016 Category: American Health Source Type: news

Preventing Medication Errors: Lessons From a Patient
A Nurse Aide, an Emergency Room Clerk, and a Patient I have great appreciation for doctors and nurses, hospitals, and patients. In high school I worked as a nurse aide in a convalescent home. I fed, dressed, and showered elderly patients, many of them immobile. I shaved gentlemen's facial stubble and polished ladies' fingernails. In college and in graduate school, I worked as an emergency room clerk. I witnessed a lot, including amazing doctors and nurses caring for patients and saving lives. I have also been a patient. First, when I had an appendectomy at age eight and then when I gave natural childbirth twice. All were...
Source: Healthy Living - The Huffington Post - May 2, 2016 Category: Consumer Health News Source Type: news