Two More Alzheimer's Drug Candidates Fail Two More Alzheimer's Drug Candidates Fail
The BACE inhibitor lanabecestat and the antibiotic minocycline failed to slow cognitive decline in randomized controlled trials.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - December 9, 2019 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

How Is Hidradenitis Suppurativa Treated?
Discussion Hidradenitis suppurativa (HS) is a recurrent, chronic inflammatory disease of the hair follicles particularly in the apocrine gland-bearing areas of the axilla, inguinal, perianal, mammary and inframammary areas. Onset is usually after puberty, in the early 20s. It is more common in females than males. Prevalence is estimated to be 0.05- 4.1%. It can be associated with premature adrenarche, metabolic syndrome and obesity. The lesions are often pruritic, painful, and with malodorous purulent drainage. It often begins with comedomes and tender nodules, and can easily progress to painful abscesses with purulent f...
Source: PediatricEducation.org - November 25, 2019 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Amzeeq (Minocycline Topical Foam) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - October 30, 2019 Category: Drugs & Pharmacology Source Type: news

First Topical Form of Minocycline for Acne
FDA Clears First Topical Form of Minocycline for Acne (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - October 22, 2019 Category: General Medicine Source Type: news

FDA Clears First Topical Form of Minocycline for Acne FDA Clears First Topical Form of Minocycline for Acne
Minocycline topical foam (Amzeeq) is for the treatment of inflammatory lesions of nonnodular moderate to severe acne vulgaris in adults and children aged 9 years or older.FDA Approvals (Source: Medscape FamilyMedicine Headlines)
Source: Medscape FamilyMedicine Headlines - October 21, 2019 Category: Primary Care Tags: Dermatology News Alert Source Type: news

FDA Approves Amzeeq (minocycline) Topical Foam for the Treatment of Moderate to Severe Acne
REHOVOT, Israel and BRIDGEWATER, N.J., Oct. 18, 2019 (GLOBE NEWSWIRE) -- Foamix Pharmaceuticals Ltd. (Nasdaq: FOMX) (“Foamix” or the“Company”), a specialty pharmaceutical company, today announced that the U.S. Food and Drug... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - October 19, 2019 Category: Drugs & Pharmacology Source Type: news

Foamix Announces FDA Acceptance of its New Drug Application for FMX103 Minocycline Foam for the Treatment of Moderate-to-Severe Papulopustular Rosacea
REHOVOT, Israel and BRIDGEWATER, N.J., Oct. 17, 2019 (GLOBE NEWSWIRE) -- Foamix Pharmaceuticals Ltd. (Nasdaq: FOMX), a clinical stage specialty pharmaceutical company focused on developing and commercializing... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - October 18, 2019 Category: Drugs & Pharmacology Source Type: news

Medical News Today: Can minocycline help treat rheumatoid arthritis?
Minocycline is an antibiotic that can reduce inflammation. Minocycline can relieve the symptoms of rheumatoid arthritis (RA), but newer treatments are more common options. Learn about minocycline and other treatments for RA here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 11, 2019 Category: Consumer Health News Tags: Rheumatoid Arthritis Source Type: news

Medical News Today: Common acne drug could prevent artery hardening
Scientists have identified the mechanism that causes artery hardening and have shown that the antibiotic minocycline can prevent the process in rats. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 11, 2019 Category: Consumer Health News Tags: Vascular Source Type: news

Acne drug could prevent deadly heart attacks and strokes
Scientists from the University of Cambridge were surprised to discover molecules in the antibiotic minocycline block the pathway that leads to deposits in the circulatory system. (Source: the Mail online | Health)
Source: the Mail online | Health - June 11, 2019 Category: Consumer Health News Source Type: news

Clinical features and antimicrobial susceptibility profiles of culture-proven neonatal sepsis in a tertiary children's hospital, 2013 to 2017.
Neonatal sepsis (NS) remains a major cause of morbidity and mortality in neonates, but data on the etiology and antibiotic susceptibility patterns of pathogens are limited. The aim of this study was to analyze the clinical characteristics, risk factors, and the antibiotic susceptibility patterns of pathogenic microbes associated with NS at a tertiary children's hospital in Shanghai, China. Most isolates of Gram-positive bacteria were sensitive to vancomycin, linezolid, minocycline and tigecycline, of which more than 90% were resistant to penicillin. Most isolates of Gram-negative bacteria were sensitive to amikacin and imi...
Source: Current Awareness Service for Health (CASH) - May 29, 2019 Category: Consumer Health News Source Type: news

Foamix Announces FDA Acceptance of New Drug Application for FMX101 Minocycline Foam for the Treatment of Moderate-to-Severe Acne
REHOVOT, Israel, and BRIDGEWATER, N.J., March 07, 2019 (GLOBE NEWSWIRE) -- Foamix Pharmaceuticals Ltd. (Nasdaq: FOMX), a clinical stage specialty pharmaceutical company focused on developing and commercializing proprietary topical therapies to... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - March 7, 2019 Category: Drugs & Pharmacology Source Type: news

Minocycline for Acne Changes Skin Microbiota
(MedPage Today) -- Findings in pilot study may explain adverse effects of antibiotic therapy in acne (Source: MedPage Today Dermatology)
Source: MedPage Today Dermatology - February 16, 2019 Category: Dermatology Source Type: news

Minocycline Reduce Synaptic Pruning in Schizophrenia Cell Models Minocycline Reduce Synaptic Pruning in Schizophrenia Cell Models
Minocycline reduces excessive synaptic pruning in schizophrenia patient-derived cell models, suggesting that it might delay or prevent the onset of schizophrenia in some individuals, according to new research.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - February 13, 2019 Category: Pathology Tags: Psychiatry News Source Type: news

Antibiotic could protect against neurodegenerative diseases during aging
(eLife) An antibiotic, minocycline, can increase the lifespan of roundworms by preventing the build-up of proteins during aging, a study in the open-access journal eLife reports. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 28, 2018 Category: International Medicine & Public Health Source Type: news

Antibiotic Fails to Cut Negative Symptoms of Schizophrenia Antibiotic Fails to Cut Negative Symptoms of Schizophrenia
Adjunctive minocycline failed to ease negative symptoms or inflammatory or neuropathic processes in patients with recent-onset psychosis in what is believed to be the largest trial to date.Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - October 17, 2018 Category: Psychiatry Tags: Psychiatry News Source Type: news

Woman's tongue turned BLACK and 'hairy' because of an antibiotic
Doctors in St Louis have revealed the unnamed 55-year-old's bizarre side effect was caused by minocycline, an antibiotic that was given to her to combat a wound infection. (Source: the Mail online | Health)
Source: the Mail online | Health - September 5, 2018 Category: Consumer Health News Source Type: news

Solodyn (Minocycline Hydrochloride) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - August 21, 2018 Category: Drugs & Pharmacology Source Type: news

Common Medications Can Cause Drug-Induced Lupus
BOSTON (CBS) – A busy mom of two young kids, Faryn Savasta of Westborough is constantly on the go. But chasing after her kids would have been impossible a few years ago. “All of a sudden I woke up one day and I felt like I couldn’t move,” she said. “My legs felt like giant rocks and I couldn’t move them.” At the time, Faryn was a newlywed and looking forward to starting a family. Instead she was depending on her husband for basic needs. “Bring me to the bathroom, help me get in and out of bed. It was shocking,” she recalled. Faryn Savasta of Westborough. (WBZ-TV) A...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - July 7, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Healthwatch Seen On WBZ-TV Syndicated Local Dr. Mallika Marshall Local TV Lupus Source Type: news

Traumatic brain injury: minocycline reduces microglial activation but increases neurodegeneration after TBI - Wood H.
[Abstract unavailable] Language: en... (Source: SafetyLit)
Source: SafetyLit - February 5, 2018 Category: International Medicine & Public Health Tags: TBI Source Type: news

Minocycline As an Alternative to Doxycycline for Rosacea Minocycline As an Alternative to Doxycycline for Rosacea
A new study suggests that minocycline is as effective as doxycycline in treating papulopustular rosacea; but adverse effects might relegate it to a second-line option.The British Journal of Dermatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 25, 2017 Category: Consumer Health News Tags: Dermatology Journal Article Source Type: news

Antibiotic Shows Promise for Major Depression Antibiotic Shows Promise for Major Depression
Minocycline, a broad-spectrum antibiotic frequently used to treat acne, may have utility as an adjunct for treating depression, especially by improving global functioning and quality of life.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 12, 2017 Category: Consumer Health News Tags: Psychiatry News Source Type: news

Ximino (Minocycline Hydrochloride) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - June 21, 2017 Category: Drugs & Pharmacology Source Type: news

PodMed: A Medical News Roundup From Johns Hopkins (with audio)
(MedPage Today) -- This week's topics include treating resistant hepatitis C infection, a new regimen for breast cancer, evolution of non-small cell lung cancer, and minocycline for MS (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - June 4, 2017 Category: Gastroenterology Source Type: news

Old Antibiotic May Slow Conversion From CIS to MS Old Antibiotic May Slow Conversion From CIS to MS
Treatment with minocycline met the randomized controlled trial's primary endpoint, decreasing conversion vs placebo within 6 months, but between-group differences weren't sustained at 24 months.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 1, 2017 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Minocycline Might Help Prevent Progression to Multiple Sclerosis (FREE)
By the Editors The antibiotic minocycline might help prevent progression to multiple sclerosis in patients with an isolated demyelinating event, a New England Journal of … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - June 1, 2017 Category: Primary Care Source Type: news

Common acne medicine reduces risk of multiple sclerosis, Calgary researchers find
Millions of people already take minocycline to treat acne, but University of Calgary researchers have found the inexpensive antibiotic also helps to control multiple sclerosis. (Source: CBC | Health)
Source: CBC | Health - May 31, 2017 Category: Consumer Health News Tags: News/Canada/Calgary Source Type: news

Arestin (Minocycline Hydrochloride Microspheres) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - May 22, 2017 Category: Drugs & Pharmacology Source Type: news

Minolira (Minocycline Hydrochloride Extended-Release Tablets) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - May 19, 2017 Category: Drugs & Pharmacology Source Type: news

What Are Options for Acne Treatment?
Discussion Acne vulgaris or acne is a problem of the pilosebaceous follicle. It occurs most prominently where sebaceous glands are abundant especially the face, neck, and upper back. Sebum production increases because of androgens. Keratin and sebum clog the pores of the pilosebaceous unit causing hyperkeratosis (clogged pilosebaceous unit = clogged pores = comedomes). Propionibacterium acnes, a gram-negative anaerobe, multiplies in the sebaceous unit causing an inflammatory reaction resulting in moderate or severe acne. Skin lesions include: Comedomal acne has comedomes White heads = closed comedomes Black heads = open...
Source: PediatricEducation.org - January 16, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Minocin (Minocycline Hydrochloride Oral Suspension) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 15, 2016 Category: Drugs & Pharmacology Source Type: news

Minocin Injection (Minocycline Inj) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 15, 2016 Category: Drugs & Pharmacology Source Type: news

Catheter impregnation, coating or bonding for reducing central venous catheter-related infections in adults
This Cochrane Review informed a practice changing update on Dynamed Plus. It found that antimicrobial coatings that appear to reduce risk of central venous catheter-related bloodstream infection include minocycline-rifampicin, chlorhexidine silver sulfadiazine, silver, and heparin, but antimicrobial coatings do not appear to reduce risk of sepsis or mortality (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - December 2, 2016 Category: Consumer Health News Source Type: news

minocycline (Dynacin, Minocin)
Title: minocycline (Dynacin, Minocin)Category: MedicationsCreated: 3/2/2005 12:00:00 AMLast Editorial Review: 9/14/2016 12:00:00 AM (Source: MedicineNet Skin General)
Source: MedicineNet Skin General - September 14, 2016 Category: Dermatology Source Type: news

Minocin Capsules (Minocycline) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 8, 2016 Category: Drugs & Pharmacology Source Type: news

BioPharmX begins patient enrolment in Phase IIb OPAL study of BPX-01 to treat acne vulgaris
US-based pharmaceutical company BioPharmX has enrolled the first patient in its Phase IIb tOPicAL Minocycline Gel (OPAL) clinical trial of BPX-01 to treat acne vulgaris. (Source: Drug Development Technology)
Source: Drug Development Technology - August 25, 2016 Category: Pharmaceuticals Source Type: news

MassDevice.com +5 | The top 5 medtech stories for June 22, 2016
Say hello to MassDevice +5, a bite-sized view of the top five medtech stories of the day. This feature of MassDevice.com’s coverage highlights our 5 biggest and most influential stories from the day’s news to make sure you’re up to date on the headlines that continue to shape the medical device industry. Get this in your inbox everyday by subscribing to our newsletters.   5. J&J investor relations veep Mehrotra retires, Wolk steps up Johnson & Johnson said today its 10-year vice president of investor relations Louise Mehrotra will retire, effective January 2017, to be replaced by Joseph Wol...
Source: Mass Device - June 22, 2016 Category: Medical Equipment Authors: MassDevice Tags: News Well Plus 5 Source Type: news

FDA warns Medtronic’s Tyrx on anti-bacterial envelopes
The FDA sent a warning letter earlier this month to Medtronic (NYSE:MDT) subsidiary Tyrx over problems with its process validation and quality systems. The Tyrx envelopes are designed to elute a pair of anti-microbial drugs, minocycline and rifampin, for 7 days before dissolving over a period of roughly 9 weeks. They’re cleared for use with pacemakers, implantable cardioverter-defibrillators, cardiac resynchronization therapy devices, deep-brain stimulators, sacral nerve stimulators, spinal cord stimulators and vagus nerve stimulators. Tyrx, which Medtronic acquired for $160 million in Januar...
Source: Mass Device - June 22, 2016 Category: Medical Equipment Authors: Brad Perriello Tags: Regulatory/Compliance Surgical Medtronic TYRX Inc. Warning Letter Source Type: news

Adjunctive minocycline microspheres
The aim of this study was to compare the effects of adjunctive Minocycline HCl Microspheres (Arestin) with debridement alone on the levels of 40 subgingival bacterial species in the treatment of peri-implantitis. Reseachers recruited 208 subjects (from 11 centers in the USA) with at least 1 implant with peri-implantitis and randomized to receive either mechanical debridement alone (n=104) or mechanical debridement followed by Arestin (1 mg) (n=104) at baseline and day 90. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 21, 2016 Category: Science Source Type: news

Meibomian Gland Dysfunction: Poor Evidence for Oral Antibiotics Meibomian Gland Dysfunction: Poor Evidence for Oral Antibiotics
More research is needed to define the role of doxycycline, minocycline, and azithromycin in this difficult-to-treat condition. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 29, 2015 Category: Consumer Health News Tags: Ophthalmology News Source Type: news

Old Drug Has New Promise in MSOld Drug Has New Promise in MS
Minocycline, an antibiotic that has been around for decades, reduced the risk for progression from clinically isolated syndrome to definite multiple sclerosis in a new study. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - October 14, 2015 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Tried-and-True Antibiotic May Block Conversion to MS (CME/CE)
(MedPage Today) -- Minocycline seemed to reduce progression to multiple sclerosis after first demyelinating event (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - October 10, 2015 Category: Neurology Source Type: news

FDA clears Medtronic’s Tyrx envelope for DBS devices
Medtronic (NYSE:MDT) said today that it’s launching its Tyrx surgical envelope in the U.S. for use with deep-brain stimulation devices, after it won 510(k) clearance from the FDA for use of the infection-fighting envelope with implantable neurostimulators. Fridley, Minn.-based Medtronic said it’s planning to make the Tyrx device, acquired for $160 million in January 2014, available for other neurostim indications “in the coming months.” The device is designed to elute a pair of anti-microbial drugs, minocycline and rifampin, for 7 days. The envelope is designed to then dissolve over a...
Source: Mass Device - October 8, 2015 Category: Medical Equipment Authors: Brad Perriello Tags: Cardiovascular Food & Drug Administration (FDA) Neuromodulation/Neurostimulation Regulatory/Compliance Surgical Medtronic TYRX Inc. Source Type: news

What Are Common Drug Eruptions in Children?
Patient Presentation A 4-year-old female came to clinic because of a rash for 24 hours. The pruritic rash began the evening before with a few red spots on her trunk. She had slept well, but this morning they were spreading and enlarging in size on her trunk, neck and extremities and did not seem to come and go. She also had a fever and her mother thought that she wasn’t moving as well and seemed to be sore. The patient had been started on cefaclor 9 days earlier for an ear infection and upper respiratory tract infection symptoms. She had previously taken penicillins and cephalosporin antibiotics without any problems...
Source: PediatricEducation.org - July 27, 2015 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Medical device companies boost guarantees to hospitals
Medical device companies are reportedly boosting their guarantees to hospital customers, seeking to bolster flagging sales growth and downward price pressure, offering to compensate them if their devices fail to perform. Medtronic (NYSE:MDT), Johnson & Johnson (NYSE:JNJ) and St. Jude Medical (NYSE:STJ) are among the 1st to provide the newer guarantees, some of which offer to share in the cost of follow-up treatment tied to their heart devices, company executives told Reuters. Orthopedic device companies are also mulling similar guarantees for their hip and knee implants. But even that may not be eno...
Source: Mass Device - July 8, 2015 Category: Medical Equipment Authors: Brad Perriello Tags: Business/Financial News BioSense Webster Inc. Ethicon Inc. Johnson & Johnson medtronic St. Jude Medical Source Type: news

Minocycline Effective for Erythema Nodosum LeprosumMinocycline Effective for Erythema Nodosum Leprosum
Minocycline is effective for treating recurrent and chronic erythema nodosum leprosum (ENL), according to a pilot study in 10 patients with multibacillary leprosy. Reuters Health Information (Source: Medscape Dermatology Headlines)
Source: Medscape Dermatology Headlines - April 30, 2015 Category: Dermatology Tags: Dermatology News Source Type: news

Minocin (Minocycline Hydrochloride Oral Suspension) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - April 14, 2015 Category: Drugs & Pharmacology Source Type: news

Hovione Files Milestone IND for Topical Zit Zapper
Minocycline gel is a novel formulation to administer topically using a new patented crystalline base form of minocycline (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - December 9, 2014 Category: Pharmaceuticals Source Type: news

minocycline (Dynacin, Minocin)
Title: minocycline (Dynacin, Minocin)Category: MedicationsCreated: 3/2/2005 12:00:00 AMLast Editorial Review: 10/3/2014 12:00:00 AM (Source: MedicineNet Skin General)
Source: MedicineNet Skin General - October 3, 2014 Category: Dermatology Source Type: news