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Antibiotic susceptibility and genomic analysis of ciprofloxacin-resistant and ESBLs-producing Escherichia coli in vegetables and their irrigation water and growing soil
In conclusion, our research highlights the widespread presence of CIPRE. coli in irrigation water and thoroughly examines the genetic characteristics of CIPR-ESBLs-producing E. coli strains, underlining the need for ongoing monitoring and management to reduce multidrug-resistant bacteria in vegetables and their environment.PMID:38368793 | DOI:10.1016/j.ijfoodmicro.2024.110629 (Source: International Journal of Food Microbiology)
Source: International Journal of Food Microbiology - February 18, 2024 Category: Food Science Authors: Jiali Sun Jinghan Dai Jin Chen Yuanjie He Li Su Mengqing Gong Mengyuan Cao Kexin Wei Yi You Lisha Liu Li Bai Shenghui Cui Jia Chen Baowei Yang Source Type: research

Spaced double hydrogen bonding for highly efficient and selective photocatalytic air reductive H2O2 synthesis
Angew Chem Int Ed Engl. 2024 Feb 14:e202400857. doi: 10.1002/anie.202400857. Online ahead of print.ABSTRACTPhotocatalytic oxygen reductive H2O2 production is a promising approach to alternative industrial anthraquinone processes while suffering from the requirement of pure O2 feedstock for practical application. Herein, we report a spaced double hydrogen bond (IC-H-bond) through multi-component Radziszewski reaction in an imidazole poly-ionic-liquid composite (SI-PIL-TiO2) and levofloxacin hydrochloride (LEV) electron donor for highly efficient and selective photocatalytic air reductive H2O2 production. It is found that th...
Source: Angewandte Chemie - February 15, 2024 Category: Chemistry Authors: Cheng Yu Jie Jin Huan Yan Guosheng Zhou Yangrui Xu Liguang Tang Xinlin Liu Hongping Li Kan Zhang Ziyang Lu Source Type: research

Identifying the Best Initial Oral Antibiotics for Adults with Community-Acquired Pneumonia: A Network Meta-Analysis
ConclusionWe observed trends toward a better clinical response and lower mortality for quinolones as empiric antibiotics for CAP, but found no conclusive evidence of any antibiotic being clearly more effective than another. More trials are needed to inform guideline recommendations on the most effective antibiotic regimens for outpatients with mild to moderate CAP. (Source: Journal of General Internal Medicine)
Source: Journal of General Internal Medicine - February 15, 2024 Category: Internal Medicine Source Type: research

Cu 2 O/WO 3 S-scheme heterojunctions for photocatalytic degradation of levofloxacin based on coordination activation
Chemosphere. 2024 Feb 12:141446. doi: 10.1016/j.chemosphere.2024.141446. Online ahead of print.ABSTRACTHeterogeneous photocatalytic degradation of antibiotic involves the activation of antibiotic molecules and the photocatalytic oxidation process. However, the simultaneous improvement of these processes is still a challenge. Herein, S-scheme heterojunctions consisted of Cu2O nanocluster with defective WO3 nanosheets were constructed for efficient photocatalytic degradation of levofloxacin (LVX). The typical CNS-5 composite (5 wt% Cu2O/WO3) achieves an optimal LVX degradation efficiency of 97.9% within 80 min. The spatial c...
Source: Chemosphere - February 14, 2024 Category: Chemistry Authors: Qi Chen Ling Hu Yingzhang Shi Cheng Liu Yidong Hou Jinhong Bi Jimmy C Yu Ling Wu Source Type: research

Biomass ‐Derived Carbon Quantum Dots Chemical Bonding with Sn‐Doped Bi2O2CO3 Endowed Fast Carriers’ Dynamics and Stabilized Oxygen Vacancies for Efficient Decontamination of Combined Pollutants
Bagasse-derived carbon quantum dots are loaded on the Sn(IV)-doped Bi2O2CO3 via hydrothermal procedure to create Bi ─O─C chemical bonding at the interface, which not only provide efficient atomic-level interfacial electron channels for accelerating carriers transfer, but also replace the oxygen vacancies as a new molecular oxygen adsorption site to improve the durability of the oxygen vacancies. AbstractSurface defects on photocatalysts could promote carrier separation and generate unsaturated sites for chemisorption and reactant activation. Nevertheless, the inactivation of oxygen vacancies (OVs) would deteriorate cat...
Source: Small - February 12, 2024 Category: Nanotechnology Authors: Tingting Zhu, Zuofang Yao, Jinghui Pan, Fengtao Hu, Shiming Zhang, Songyu Fan, Chenchen Xing, Zebin Yu, Shuangfei Wang, Yanping Hou Tags: Research Article Source Type: research

Phenotypic heterogeneity unveils a negative correlation between antibiotic resistance and quorum sensing in Pseudomonas aeruginosa clinical isolates
In this study, 67 P. aeruginosa strains were isolated from the lungs of 14 patients with chronic obstructive pulmonary disease, followed by determining their genetic relationship, QS-related phenotypes and resistance to commonly used antibiotics. The integrity of P. aeruginosa QS system was checked by DNA sequencing. The relationship between the QS system and antibiotic resistance was then assessed by correlation analyses. The function of the LasR protein and bacterial virulence were evaluated through homology modeling and nematode-infection assay. The influence of antibiotic on the development of extracellular protease pr...
Source: Frontiers in Microbiology - February 12, 2024 Category: Microbiology Source Type: research

Intraperitoneal vancomycin plus levofloxacin for the treatment of peritoneal dialysis-related peritonitis in patients with no response to cefazolin plus ceftazidime
CONCLUSION: Vancomycin plus levofloxacin may be effective if patients are not responsive to cefazolin plus ceftazidime.PMID:38329920 | DOI:10.5414/CN111186 (Source: Clinical Nephrology)
Source: Clinical Nephrology - February 8, 2024 Category: Urology & Nephrology Authors: Jiafan Zhou Yajuan Huang Xing Zhang Liping Xiong Rui Zhang Hongrui Shi Source Type: research

Fabrication of levofloxacin-loaded porcine acellular dermal matrix hydrogel and functional assessment in urinary tract infection
Bacterial cystitis, a commonly occurring urinary tract infection (UTI), is renowned for its extensive prevalence and tendency to recur. Despite the extensive utilization of levofloxacin as a conventional thera... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - February 7, 2024 Category: Nanotechnology Authors: Yi Yang, Guang-Wei Yang, Jian-Juan Lu, Hao-Ran Chen, Ya-Qin Guo, Ning Yang, Yun-Zhu Zhu, Xiao-Qiang Liu, Ting-Ting Su, Yan-Yan Liu, Liang Yu, Ya-Sheng Li, Li-Fen Hu and Jia-Bin Li Tags: Original Paper Source Type: research

Success of susceptibility-guided eradication of Helicobacter pylori in a region with high secondary clarithromycin and levofloxacin resistance rates
CONCLUSION: H. pylori presented high secondary resistance rates to CLA and LFX. For patients with previous treatment failures, treatments should be guided by antibiotic susceptibility tests or regional antibiotic resistance profile.PMID:38312120 | PMC:PMC10835524 | DOI:10.3748/wjg.v30.i2.184 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - February 5, 2024 Category: Gastroenterology Authors: Yan-Meng Wang Mo-Ye Chen Jing Chen Xin-He Zhang Yan Feng Yu-Xi Han Yi-Ling Li Source Type: research

Success of susceptibility-guided eradication of Helicobacter pylori in a region with high secondary clarithromycin and levofloxacin resistance rates
CONCLUSION: H. pylori presented high secondary resistance rates to CLA and LFX. For patients with previous treatment failures, treatments should be guided by antibiotic susceptibility tests or regional antibiotic resistance profile.PMID:38312120 | PMC:PMC10835524 | DOI:10.3748/wjg.v30.i2.184 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - February 5, 2024 Category: Gastroenterology Authors: Yan-Meng Wang Mo-Ye Chen Jing Chen Xin-He Zhang Yan Feng Yu-Xi Han Yi-Ling Li Source Type: research