Sex Specific Outcomes After Ischemic Stroke
N/A (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 2, 2024 Category: Neurology Authors: Fransisca Indraswari, Shadi Yaghi, Farhan Khan Source Type: research
Stroke and Transient Ischemic Attack
Prim Care. 2024 Jun;51(2):283-297. doi: 10.1016/j.pop.2024.02.004. Epub 2024 Apr 1.ABSTRACTCerebrovascular disease is a common and potentially life-threatening illness if not triaged and/or treated appropriately. The diagnosis is made based on a combination of clinical history and neuroimaging studies. The majority of strokes can be prevented, and this process often begins in the primary care office through the careful assessment of vascular risk factors. Appropriate workup aims to pinpoint a pathogenic mechanism and guide therapy. Stroke treatment has rapidly advanced over the past several years, resulting in improved out...
Source: Primary Care - May 1, 2024 Category: Primary Care Authors: Paige Banyas Ashutosh Jadhav Source Type: research
Health budget implications of mechanical thrombectomy for acute ischaemic stroke in Australia
ConclusionTreatment of AIS with a combination of MT+IV-tPA generates significant savings in the Australian healthcare system compared with IV-tPA alone. (Source: Journal of Medical Imaging and Radiation Oncology)
Source: Journal of Medical Imaging and Radiation Oncology - May 1, 2024 Category: Radiology Authors: Hal Rice,
Laetitia de Villiers,
Raffaelle Scarica,
Anne ‐Laure Bocquet,
Kelly Dargan,
Thomas Barthe Tags: Interventional Radiology —Original Article Source Type: research
Triglyceride-glucose index as a potential predictor for in-hospital mortality in critically ill patients with intracerebral hemorrhage: a multicenter, case –control study
This study aims to assess the influence of the TyG index on the clinical outcomes of... (Source: BMC Geriatrics)
Source: BMC Geriatrics - May 1, 2024 Category: Geriatrics Authors: Yang Yang, Shengru Liang, Jiangdong Liu, Minghao Man, Yue Si, Dengfeng Jia, Jianwei Li, Xiaoxi Tian and Lihong Li Tags: Research Source Type: research
Edaravone dexborneol regulates γ-aminobutyric acid transaminase in rats with acute intracerebral hemorrhage
Edaravone dexborneol is neuroprotective against ischemic stroke, with free radical-scavenging and anti-inflammatory effects, but its effects in hemorrhagic stroke remain unclear. We evaluated whether edaravone dexborneol has a neuroprotective effect in intracerebral hemorrhage, and its underlying mechanisms. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 1, 2024 Category: Neurology Authors: Rui Yang, Jia Li, Li Zhao, Ming Zhang, Yaya Qin, Xiaoqiong Tong, Shenglin Wang, Fanhui Yang, Guohui Jiang Source Type: research
Robust Ensemble of Two Different Multimodal Approaches to Segment 3D Ischemic Stroke Segmentation Using Brain Tumor Representation Among Multiple Center Datasets
AbstractIschemic stroke segmentation at an acute stage is vital in assessing the severity of patients ’ impairment and guiding therapeutic decision-making for reperfusion. Although many deep learning studies have shown attractive performance in medical segmentation, it is difficult to use these models trained on public data with private hospitals’ datasets. Here, we demonstrate an ensemble model that employs two different multimodal approaches for generalization, a more effective way to perform on external datasets. First, after we jointly train a segmentation model on diffusion-weighted imaging (DWI) and apparent diff...
Source: Journal of Digital Imaging - May 1, 2024 Category: Radiology Source Type: research
Messenger RNAs in the Whole Blood of Male and Females after Acute Ischemic Stroke using Bioinformatics
CONCLUSIONS: This study identified gender-specific mRNA expression differences in the peripheral whole blood of AIS patients. The findings provide important insights into the molecular mechanisms underlying AIS in males and females.PMID:38687860 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 30, 2024 Category: Complementary Medicine Authors: Yanchao Wang Source Type: research
Dorsal dentate gyrus mediated enriched environment-induced anxiolytic and antidepressant effects in cortical infarcted mice
This study aimed to explore the effectiveness of EE on emotional disorders after cerebral ischemia and its underling mechanism. In this study, sensorimotor cortical infarction was induced by photothrombosis with stable infarct location and volume, resulting in motor dysfunction, anxiety and depression-like behaviors in mice, with decreased ALFF and ReHo values and decreased c-fos expression in the infarction area and adjacent regions. Seven days' EE treatment significantly improved motor function of contralateral forelimb and exhibited anxiolytic and antidepressant effects in infarcted mice. Compared to the mice housing in...
Source: Experimental Neurology - April 30, 2024 Category: Neurology Authors: Dan Huang Yunhui Fan Jingjun Zhang Qianfeng Wang Ming Ding Ruiqing Hou Kewei Yu Xiao Xiao Yi Wu Junfa Wu Source Type: research
Atrial Septal Abnormalities and Cryptogenic Stroke: A Cross-Sectional Study
CONCLUSION: Based on our results, the prevalence of atrial septal abnormalities was relatively high. Considering these issues and the importance of preventing neurological accidents in patients, especially young people, it is recommended to always consider atrial septal disorders and, if diagnosed, to carry out the necessary treatment in this field.PMID:38685781 | DOI:10.2174/011871529X294809240415070950 (Source: Cardiovascular and Hematological Disorders Drug Targets)
Source: Cardiovascular and Hematological Disorders Drug Targets - April 30, 2024 Category: Drugs & Pharmacology Authors: Marzieh Aliramezany Mansoor Moazenzadeh Amin Sayyadi Khadijeh Mohammadi Hamidreza Barzegar Maryam Aliramezany Source Type: research
Overview of systematic reviews comparing endovascular to best medical treatment for large-vessel occlusion acute ischaemic stroke: an umbrella review
CONCLUSION: In patients with AIS due to LVO in the anterior or posterior circulation, within 24 h from symptom onset, EVT improves functional outcomes and increases the chance of survival despite increased sICH risk.REGISTRATION: PROSPERO Registration Number CRD42023461138.PMID:38685935 | PMC:PMC11057347 | DOI:10.1177/17562864241246938 (Source: Adv Data)
Source: Adv Data - April 30, 2024 Category: Epidemiology Authors: Apostolos Safouris Lina Palaiodimou Aristeidis H Katsanos Odysseas Kargiotis Konstantinos I Bougioukas Klearchos Psychogios Tatiana Sidiropoulou Stavros Spiliopoulos Marios-Nikos Psychogios Georgios Magoufis Guillaume Turc Georgios Tsivgoulis Source Type: research
Automatic assessment of DWI-ASPECTS for acute ischemic stroke based on deep learning
CONCLUSIONS: This study proposed an automated model for ASPECTS scoring of patients with acute ischemic stroke based on DWI images. Experimental results show that the method of segmentation first and then classification is feasible. Our method has the potential to assist physicians in the Alberta Stroke Program with early CT scoring and clinical stroke diagnosis.PMID:38687043 | DOI:10.1002/mp.17101 (Source: Health Physics)
Source: Health Physics - April 30, 2024 Category: Physics Authors: Ting Fang Zhuoyun Jiang Yuxi Zhou Shouqiang Jia Jiaqi Zhao Shengdong Nie Source Type: research
Targeting pyroptosis to treat ischemic stroke: From molecular pathways to treatment strategy
Int Immunopharmacol. 2024 Apr 29;133:112168. doi: 10.1016/j.intimp.2024.112168. Online ahead of print.ABSTRACTIschemic stroke is the primary reason for human disability and death, but the available treatment options are limited. Hence, it is imperative to explore novel and efficient therapies. In recent years, pyroptosis (a pro-inflammatory cell death characterized by inflammation) has emerged as an important pathological mechanism in ischemic stroke that can cause cell death through plasma membrane rupture and release of inflammatory cytokines. Pyroptosis is closely associated with inflammation, which exacerbates the infl...
Source: International Immunopharmacology - April 30, 2024 Category: Allergy & Immunology Authors: Lina Li Chonglin Shi Fang Dong Guangyu Xu Mingcheng Lei Feng Zhang Source Type: research
Messenger RNAs in the Whole Blood of Male and Females after Acute Ischemic Stroke using Bioinformatics
CONCLUSIONS: This study identified gender-specific mRNA expression differences in the peripheral whole blood of AIS patients. The findings provide important insights into the molecular mechanisms underlying AIS in males and females.PMID:38687860 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 30, 2024 Category: Complementary Medicine Authors: Yanchao Wang Source Type: research
Dorsal dentate gyrus mediated enriched environment-induced anxiolytic and antidepressant effects in cortical infarcted mice
This study aimed to explore the effectiveness of EE on emotional disorders after cerebral ischemia and its underling mechanism. In this study, sensorimotor cortical infarction was induced by photothrombosis with stable infarct location and volume, resulting in motor dysfunction, anxiety and depression-like behaviors in mice, with decreased ALFF and ReHo values and decreased c-fos expression in the infarction area and adjacent regions. Seven days' EE treatment significantly improved motor function of contralateral forelimb and exhibited anxiolytic and antidepressant effects in infarcted mice. Compared to the mice housing in...
Source: Experimental Neurology - April 30, 2024 Category: Neurology Authors: Dan Huang Yunhui Fan Jingjun Zhang Qianfeng Wang Ming Ding Ruiqing Hou Kewei Yu Xiao Xiao Yi Wu Junfa Wu Source Type: research
Atrial Septal Abnormalities and Cryptogenic Stroke: A Cross-Sectional Study
CONCLUSION: Based on our results, the prevalence of atrial septal abnormalities was relatively high. Considering these issues and the importance of preventing neurological accidents in patients, especially young people, it is recommended to always consider atrial septal disorders and, if diagnosed, to carry out the necessary treatment in this field.PMID:38685781 | DOI:10.2174/011871529X294809240415070950 (Source: Cardiovascular and Hematological Disorders Drug Targets)
Source: Cardiovascular and Hematological Disorders Drug Targets - April 30, 2024 Category: Drugs & Pharmacology Authors: Marzieh Aliramezany Mansoor Moazenzadeh Amin Sayyadi Khadijeh Mohammadi Hamidreza Barzegar Maryam Aliramezany Source Type: research
