Safety and effectiveness of anticoagulation in the management of acute stroke and transient ischemic attack due to intracranial and extracranial non-occlusive thrombus
CONCLUSION: Anticoagulant treatment is safe and effective in symptomatic patients with intracranial or extracranial artery nonocclusive thrombus, regardless of the anticoagulant type, thrombus location and size.PMID:38643651 | DOI:10.1016/j.jocn.2024.04.012 (Source: Atherosclerosis)
Source: Atherosclerosis - April 21, 2024 Category: Cardiology Authors: Aysenur Onalan Erdem Gurkas Cetin Kursad Akpinar Ozlem Aykac Zehra Uysal Kocabas Hasan Dogan Musa Temel Atilla Ozcan Ozdemir Source Type: research

Headpulse measurement can reliably identify large-vessel occlusion stroke in prehospital suspected stroke patients: Results from the EPISODE-PS-COVID study
CONCLUSIONS: Obtaining adequate recordings with a CA headset is highly feasible in the prehospital environment. Use of the device algorithm incorporating both CA and LAMS data for LVO detection resulted in significantly higher sensitivity without reduced specificity when compared to the use of LAMS alone.PMID:38643419 | DOI:10.1111/acem.14919 (Source: Accident and Emergency Nursing)
Source: Accident and Emergency Nursing - April 21, 2024 Category: Emergency Medicine Authors: James H Paxton Kevin J Keenan John M Wilburn Stefanie L Wise Howard A Klausner Matthew T Ball Robert B Dunne K Derek Kreitel Larry F Morgan William D Fales Debbie Madhok Nobl Barazangi Steven T McLean Katherine Cross Lisa Distenfield Jordan Sykes Paul Lov Source Type: research

Hypercapnic hypoxia as a rehabilitation method for patients after ischemic stroke
CONCLUSION: Respiratory training with hypercapnic hypoxia improves the functional state of the nervous system in patients with ischemic stroke. After conducting further clarifying studies, hypercapnic hypoxia can be considered as an effective method of neurorehabilitation, which can be used as early as 48-72 hours after the onset of stroke.PMID:38643375 | DOI:10.1080/01616412.2024.2343510 (Source: Neurological Research)
Source: Neurological Research - April 21, 2024 Category: Neurology Authors: Tatiana M Alekseeva Maria P Topuzova Vladimir P Kulikov Pavel D Kovzelev Mark G Kosenko Pavel P Tregub Source Type: research

Network analysis of microbiome and metabolome to explore the mechanism of raw rhubarb in the protection against ischemic stroke via microbiota-gut-brain axis
In conclusion, our work demonstrated that RR could effectively ameliorate ischemic stroke by modulating the microbiota and metabolic disorders.PMID:38643860 | DOI:10.1016/j.fitote.2024.105969 (Source: Fitoterapia)
Source: Fitoterapia - April 21, 2024 Category: Biochemistry Authors: Minghua Xian Zuqing Ma Sikai Zhan Lin Shen Ting Li Huiting Lin Mingmin Huang Jiale Cai Tao Hu Jiaying Liang Shengwang Liang Shumei Wang Source Type: research

Discovery of neuroprotective Agents: Potent, brain Penetrating, lipoic acid derivatives for the potential treatment of ischemic stroke by regulating oxidative stress and inflammation - a Preliminary study
In conclusion, AA-9 may be a promising neuroprotective agent for the treatment of ischemic stroke and warrants further investigation.PMID:38643566 | DOI:10.1016/j.bioorg.2024.107339 (Source: Bioorganic Chemistry)
Source: Bioorganic Chemistry - April 21, 2024 Category: Chemistry Authors: Chenchen Zhu Yun Wang Yi Li Tingfang Wang Fei Ye Wei Su Ting Chen Chuan Zhang Liyan Xiong Source Type: research

Hypercapnic hypoxia as a rehabilitation method for patients after ischemic stroke
CONCLUSION: Respiratory training with hypercapnic hypoxia improves the functional state of the nervous system in patients with ischemic stroke. After conducting further clarifying studies, hypercapnic hypoxia can be considered as an effective method of neurorehabilitation, which can be used as early as 48-72 hours after the onset of stroke.PMID:38643375 | DOI:10.1080/01616412.2024.2343510 (Source: Neurological Research)
Source: Neurological Research - April 21, 2024 Category: Neurology Authors: Tatiana M Alekseeva Maria P Topuzova Vladimir P Kulikov Pavel D Kovzelev Mark G Kosenko Pavel P Tregub Source Type: research

Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021
Lancet. 2024 Apr 15:S0140-6736(24)00757-8. doi: 10.1016/S0140-6736(24)00757-8. Online ahead of print.ABSTRACTBACKGROUND: Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury burden over time and across age groups, sexes, and locations. The availability of disease burden estimates can promote evidence-based interventions that enable public health researchers, policy makers, and other professionals to implement strategies that can mitigate diseases. It can also facilitate m...
Source: Pain Physician - April 20, 2024 Category: Anesthesiology Authors: GBD 2021 Diseases and Injuries Collaborators Source Type: research

Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021
Lancet. 2024 Apr 15:S0140-6736(24)00757-8. doi: 10.1016/S0140-6736(24)00757-8. Online ahead of print.ABSTRACTBACKGROUND: Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury burden over time and across age groups, sexes, and locations. The availability of disease burden estimates can promote evidence-based interventions that enable public health researchers, policy makers, and other professionals to implement strategies that can mitigate diseases. It can also facilitate m...
Source: Australian Family Physician - April 20, 2024 Category: Primary Care Authors: GBD 2021 Diseases and Injuries Collaborators Source Type: research

Valuing the health benefits of nature-based recreational physical activity in England
Environ Int. 2024 Apr 16;187:108667. doi: 10.1016/j.envint.2024.108667. Online ahead of print.ABSTRACTPhysical activity (PA) reduces the risk of several non-communicable diseases (NCDs). Natural environments support recreational PA. Using data including a representative cross-sectional survey of the English population, we estimated the annual value of nature-based PA conducted in England in 2019 in terms of avoided healthcare and societal costs of disease. Population-representative data from the Monitor of Engagement with the Natural Environment (MENE) survey (n = 47,580; representing 44,386,756) were used to estimate the ...
Source: Environment International - April 20, 2024 Category: Environmental Health Authors: James Grellier Mathew P White Si ân de Bell Oscar Brousse Lewis R Elliott Lora E Fleming Clare Heaviside Charles Simpson Tim Taylor Benedict W Wheeler Rebecca Lovell Source Type: research

Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021
Lancet. 2024 Apr 15:S0140-6736(24)00757-8. doi: 10.1016/S0140-6736(24)00757-8. Online ahead of print.ABSTRACTBACKGROUND: Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury burden over time and across age groups, sexes, and locations. The availability of disease burden estimates can promote evidence-based interventions that enable public health researchers, policy makers, and other professionals to implement strategies that can mitigate diseases. It can also facilitate m...
Source: Australian Family Physician - April 20, 2024 Category: Primary Care Authors: GBD 2021 Diseases and Injuries Collaborators Source Type: research

Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021
Lancet. 2024 Apr 15:S0140-6736(24)00757-8. doi: 10.1016/S0140-6736(24)00757-8. Online ahead of print.ABSTRACTBACKGROUND: Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury burden over time and across age groups, sexes, and locations. The availability of disease burden estimates can promote evidence-based interventions that enable public health researchers, policy makers, and other professionals to implement strategies that can mitigate diseases. It can also facilitate m...
Source: Australian Family Physician - April 20, 2024 Category: Primary Care Authors: GBD 2021 Diseases and Injuries Collaborators Source Type: research

Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021
Lancet. 2024 Apr 15:S0140-6736(24)00757-8. doi: 10.1016/S0140-6736(24)00757-8. Online ahead of print.ABSTRACTBACKGROUND: Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury burden over time and across age groups, sexes, and locations. The availability of disease burden estimates can promote evidence-based interventions that enable public health researchers, policy makers, and other professionals to implement strategies that can mitigate diseases. It can also facilitate m...
Source: Australian Family Physician - April 20, 2024 Category: Primary Care Authors: GBD 2021 Diseases and Injuries Collaborators Source Type: research

Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021
Lancet. 2024 Apr 15:S0140-6736(24)00757-8. doi: 10.1016/S0140-6736(24)00757-8. Online ahead of print.ABSTRACTBACKGROUND: Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury burden over time and across age groups, sexes, and locations. The availability of disease burden estimates can promote evidence-based interventions that enable public health researchers, policy makers, and other professionals to implement strategies that can mitigate diseases. It can also facilitate m...
Source: Australian Family Physician - April 20, 2024 Category: Primary Care Authors: GBD 2021 Diseases and Injuries Collaborators Source Type: research

Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021
Lancet. 2024 Apr 15:S0140-6736(24)00757-8. doi: 10.1016/S0140-6736(24)00757-8. Online ahead of print.ABSTRACTBACKGROUND: Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury burden over time and across age groups, sexes, and locations. The availability of disease burden estimates can promote evidence-based interventions that enable public health researchers, policy makers, and other professionals to implement strategies that can mitigate diseases. It can also facilitate m...
Source: Australian Family Physician - April 20, 2024 Category: Primary Care Authors: GBD 2021 Diseases and Injuries Collaborators Source Type: research

Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021
Lancet. 2024 Apr 15:S0140-6736(24)00757-8. doi: 10.1016/S0140-6736(24)00757-8. Online ahead of print.ABSTRACTBACKGROUND: Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury burden over time and across age groups, sexes, and locations. The availability of disease burden estimates can promote evidence-based interventions that enable public health researchers, policy makers, and other professionals to implement strategies that can mitigate diseases. It can also facilitate m...
Source: Australian Family Physician - April 20, 2024 Category: Primary Care Authors: GBD 2021 Diseases and Injuries Collaborators Source Type: research