Design, Synthesis, and Biological Evaluation of Novel Cinnamide Derivatives as Neuroprotective Agents for the Treatment of Cerebral Ischemia
CONCLUSION: Compounds 9t, 9u, 9y, and 9z, as potent neuroprotective agents with anti- neurotoxicity activity in vitro and anticerebral infarction efficacy in vivo, might serve as a useful molecular tool for further physiology and pathophysiology function studies, leading to potential clinical therapeutic agents for ischemic injury.PMID:38676480 | DOI:10.2174/0109298673302111240418060441 (Source: Current Medicinal Chemistry)
Source: Current Medicinal Chemistry - April 27, 2024 Category: Chemistry Authors: Yan Zhong Yi Xu Xin-Zhu Tan Yu-Ying Wang Shuang-Yan Ma Meng-Jie Gao Bin Wu Source Type: research
Optimizing catheter centering enhances mechanical thrombectomy success: Performance difference in cases using novel macrowires versus traditional microwires
CONCLUSION: Large 0.018″ or 0.024″ OD guidewires better fill the lumen of the catheter and help to center the thrombectomy system in the vessel and navigate to the clot face. This leads to a reduction in procedure time and number of passes, and an increase in first pass success, especially when treating occlusions in the ICA.PMID:38676326 | DOI:10.1177/15910199241249212 (Source: Interventional Neuroradiology)
Source: Interventional Neuroradiology - April 27, 2024 Category: Radiology Authors: Ameer E Hassan Wondwossen G Tekle Hamzah Saei Source Type: research
Nomogram to Predict 90-Day All-Cause Mortality in Acute Ischemic Stroke Patients after Endovascular Thrombectomy
CONCLUSION: Our nomogram has incorporated relevant clinical and imaging features, including neurological deterioration, age, baseline NIHSS score, occlusive vessel location, malignant brain edema, and NLR ratio, to provide an accurate and reliable prediction of 90-day all-cause mortality in AIS patients undergoing EVT.PMID:38676479 | DOI:10.2174/0115672026311086240415050048 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - April 27, 2024 Category: Neurology Authors: Shiya Zhang Shuai Yu Xiaocui Wang Zhiliang Guo Jie Hou Huaishun Wang Zhichao Huang Guodong Xiao Shoujiang You Source Type: research
Dystextia and dystypia due to phonological errors after ischemic stroke: a case report in a Japanese patient
Neurocase. 2024 Apr 26:1-8. doi: 10.1080/13554794.2024.2345403. Online ahead of print.ABSTRACTA 69-year-old Japanese male presented with acute dystextia and dystypia, defined as texting and typing impairments, respectively. His text input speed decreased due to a phonologically incorrect kana flick input on his smartphone. Additionally, dystypia occurred due to phonemic paragraphia of Romaji. Brain MRI revealed a new left lenticulostriate infarction sparing the cerebral cortex. SPECT showed reduced cerebral blood flow in the left inferior precentral frontal gyrus as well as in the infarction area. It was concluded that his...
Source: Neurocase - April 27, 2024 Category: Neurology Authors: Hiroshi Adachi Jun Numata Katsuya Nishida Hiroshi Yamasaki Naonobu Futamura Source Type: research
Investigation of the Association between Bilateral Selective Anterograde Cerebral Perfusion and Postoperative Ischemic Stroke in Obese Patients with Emergency Surgery for Acute Type A Aortic Dissection
Conclusions: A patient-tailored strategy for cerebral perfusion should be considered in obese patients, considering the high atheromatous burden of the supra-aortic vessels in these patients and the potential risk of atheromatous embolization associated with this technique.PMID:38674307 | PMC:PMC11052173 | DOI:10.3390/medicina60040661 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Mircea Robu Bogdan Radulescu Irina Maria Margarint Cornel Robu Ovidiu Stiru Andrei Iosifescu Silvia Preda Mihai Cacoveanu Cristian Voica Vlad Anton Iliescu Horatiu Moldovan Source Type: research
Long-Term Alterations in Motor Skills, Neurogenesis and Astrocyte Numbers following Transient Cerebral Ischemia in Mice
Conclusions: Our current report demonstrates the long-term effects of transient cerebral ischemia on mice functional parameters and neurogenesis progression. Our data demonstrate that transient cerebral ischemia promotes a long-lasting regenerative response in the ipsilateral brain hemisphere, specifically in the neurogenic SVZ and DG regions.PMID:38674304 | PMC:PMC11052140 | DOI:10.3390/medicina60040658 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Vladimirs Pilipenko Jolanta Upite Beatrise Luize Revina Baiba Jansone Source Type: research
Optimizing catheter centering enhances mechanical thrombectomy success: Performance difference in cases using novel macrowires versus traditional microwires
CONCLUSION: Large 0.018″ or 0.024″ OD guidewires better fill the lumen of the catheter and help to center the thrombectomy system in the vessel and navigate to the clot face. This leads to a reduction in procedure time and number of passes, and an increase in first pass success, especially when treating occlusions in the ICA.PMID:38676326 | DOI:10.1177/15910199241249212 (Source: Interventional Neuroradiology)
Source: Interventional Neuroradiology - April 27, 2024 Category: Radiology Authors: Ameer E Hassan Wondwossen G Tekle Hamzah Saei Source Type: research
Nomogram to Predict 90-Day All-Cause Mortality in Acute Ischemic Stroke Patients after Endovascular Thrombectomy
CONCLUSION: Our nomogram has incorporated relevant clinical and imaging features, including neurological deterioration, age, baseline NIHSS score, occlusive vessel location, malignant brain edema, and NLR ratio, to provide an accurate and reliable prediction of 90-day all-cause mortality in AIS patients undergoing EVT.PMID:38676479 | DOI:10.2174/0115672026311086240415050048 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - April 27, 2024 Category: Neurology Authors: Shiya Zhang Shuai Yu Xiaocui Wang Zhiliang Guo Jie Hou Huaishun Wang Zhichao Huang Guodong Xiao Shoujiang You Source Type: research
Investigation of the Association between Bilateral Selective Anterograde Cerebral Perfusion and Postoperative Ischemic Stroke in Obese Patients with Emergency Surgery for Acute Type A Aortic Dissection
Conclusions: A patient-tailored strategy for cerebral perfusion should be considered in obese patients, considering the high atheromatous burden of the supra-aortic vessels in these patients and the potential risk of atheromatous embolization associated with this technique.PMID:38674307 | PMC:PMC11052173 | DOI:10.3390/medicina60040661 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Mircea Robu Bogdan Radulescu Irina Maria Margarint Cornel Robu Ovidiu Stiru Andrei Iosifescu Silvia Preda Mihai Cacoveanu Cristian Voica Vlad Anton Iliescu Horatiu Moldovan Source Type: research
Long-Term Alterations in Motor Skills, Neurogenesis and Astrocyte Numbers following Transient Cerebral Ischemia in Mice
Conclusions: Our current report demonstrates the long-term effects of transient cerebral ischemia on mice functional parameters and neurogenesis progression. Our data demonstrate that transient cerebral ischemia promotes a long-lasting regenerative response in the ipsilateral brain hemisphere, specifically in the neurogenic SVZ and DG regions.PMID:38674304 | PMC:PMC11052140 | DOI:10.3390/medicina60040658 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Vladimirs Pilipenko Jolanta Upite Beatrise Luize Revina Baiba Jansone Source Type: research
Nomogram to Predict 90-Day All-Cause Mortality in Acute Ischemic Stroke Patients after Endovascular Thrombectomy
CONCLUSION: Our nomogram has incorporated relevant clinical and imaging features, including neurological deterioration, age, baseline NIHSS score, occlusive vessel location, malignant brain edema, and NLR ratio, to provide an accurate and reliable prediction of 90-day all-cause mortality in AIS patients undergoing EVT.PMID:38676479 | DOI:10.2174/0115672026311086240415050048 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - April 27, 2024 Category: Neurology Authors: Shiya Zhang Shuai Yu Xiaocui Wang Zhiliang Guo Jie Hou Huaishun Wang Zhichao Huang Guodong Xiao Shoujiang You Source Type: research
Investigation of the Association between Bilateral Selective Anterograde Cerebral Perfusion and Postoperative Ischemic Stroke in Obese Patients with Emergency Surgery for Acute Type A Aortic Dissection
Conclusions: A patient-tailored strategy for cerebral perfusion should be considered in obese patients, considering the high atheromatous burden of the supra-aortic vessels in these patients and the potential risk of atheromatous embolization associated with this technique.PMID:38674307 | PMC:PMC11052173 | DOI:10.3390/medicina60040661 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Mircea Robu Bogdan Radulescu Irina Maria Margarint Cornel Robu Ovidiu Stiru Andrei Iosifescu Silvia Preda Mihai Cacoveanu Cristian Voica Vlad Anton Iliescu Horatiu Moldovan Source Type: research
Long-Term Alterations in Motor Skills, Neurogenesis and Astrocyte Numbers following Transient Cerebral Ischemia in Mice
Conclusions: Our current report demonstrates the long-term effects of transient cerebral ischemia on mice functional parameters and neurogenesis progression. Our data demonstrate that transient cerebral ischemia promotes a long-lasting regenerative response in the ipsilateral brain hemisphere, specifically in the neurogenic SVZ and DG regions.PMID:38674304 | PMC:PMC11052140 | DOI:10.3390/medicina60040658 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Vladimirs Pilipenko Jolanta Upite Beatrise Luize Revina Baiba Jansone Source Type: research
Nomogram to Predict 90-Day All-Cause Mortality in Acute Ischemic Stroke Patients after Endovascular Thrombectomy
CONCLUSION: Our nomogram has incorporated relevant clinical and imaging features, including neurological deterioration, age, baseline NIHSS score, occlusive vessel location, malignant brain edema, and NLR ratio, to provide an accurate and reliable prediction of 90-day all-cause mortality in AIS patients undergoing EVT.PMID:38676479 | DOI:10.2174/0115672026311086240415050048 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - April 27, 2024 Category: Neurology Authors: Shiya Zhang Shuai Yu Xiaocui Wang Zhiliang Guo Jie Hou Huaishun Wang Zhichao Huang Guodong Xiao Shoujiang You Source Type: research
Investigation of the Association between Bilateral Selective Anterograde Cerebral Perfusion and Postoperative Ischemic Stroke in Obese Patients with Emergency Surgery for Acute Type A Aortic Dissection
Conclusions: A patient-tailored strategy for cerebral perfusion should be considered in obese patients, considering the high atheromatous burden of the supra-aortic vessels in these patients and the potential risk of atheromatous embolization associated with this technique.PMID:38674307 | PMC:PMC11052173 | DOI:10.3390/medicina60040661 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Mircea Robu Bogdan Radulescu Irina Maria Margarint Cornel Robu Ovidiu Stiru Andrei Iosifescu Silvia Preda Mihai Cacoveanu Cristian Voica Vlad Anton Iliescu Horatiu Moldovan Source Type: research
