Relationship Between Hemorrhage Type and Development of Emotional and Behavioral Dyscontrol After Hemorrhagic Stroke
CONCLUSIONS: Patients with ICH and a low GCS score at admission are at increased risk of developing EBD 3 months after hemorrhagic stroke and may benefit from early intervention.PMID:38650464 | DOI:10.1176/appi.neuropsych.20230114 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - April 23, 2024 Category: Psychiatry Authors: Daniel Talmasov Sean Kelly Sarah Ecker Anlys Olivera Aaron Lord Lindsey Gurin Koto Ishida Kara Melmed Jose Torres Cen Zhang Jennifer Frontera Ariane Lewis Source Type: research
Elevated gut microbiota metabolite bile acids confer protective effects on clinical prognosis in ischemic stroke patients
CONCLUSION: Serum TBA is an independent risk factor for disability and poor functional outcomes after AIS or TIA, and exerts a protective effects on brain.PMID:38650617 | PMC:PMC11033300 | DOI:10.3389/fnins.2024.1388748 (Source: Atherosclerosis)
Source: Atherosclerosis - April 23, 2024 Category: Cardiology Authors: Zhaobin Wang Jing Li Yingxin Xu Ye Liu Zhe Zhang Qin Xu Jinxi Lin Yong Jiang Yongjun Wang Jing Jing Anxin Wang Xia Meng Source Type: research
Thrombus composition and regulatory T cell expression are associated with clinical outcomes in acute ischemic stroke patients with thrombectomy
CONCLUSIONS: There was no significant correlation between erythrocyte and fibrin/platelet components in thrombus and functional outcome, but increased expression of regulatory T cells was associated with good functional outcome.PMID:38650441 | DOI:10.3724/zdxbyxb-2023-0424 (Source: Atherosclerosis)
Source: Atherosclerosis - April 23, 2024 Category: Cardiology Authors: Jia Luo Jun Ma Source Type: research
Knockdown of lncRNA AU020206 could inhibit microglia apoptosis in ischemic stroke
Cell Mol Biol (Noisy-le-grand). 2024 Mar 31;70(3):142-147. doi: 10.14715/cmb/2024.70.3.21.ABSTRACTThe diagnostic biomarkers associated with ischemic stroke (IS) that may have clinical utility remain elucidated. Thus, the potential functional lncRNAs in IS were explored. The Gene Expression Omnibus database provided the transcriptome profile of IS for download. WGCNA analysis and integrated bioinformatics were used to find genes that were differentially expressed (DEGs). The Starbase database created the lncRNA-based ceRNA network. In order to investigate the molecular mechanism and involved pathways of DEGs in IS, function...
Source: Cellular and Molecular Biology - April 23, 2024 Category: Molecular Biology Authors: Zhihua Chen Wei Hu Jiahong Wang Donggen Rao Jianming Zhu Source Type: research
Interrupting Effect of Social Distancing on Ischemic Heart Disease, Asthma, Stroke, and Suicide Attempt Patients by PM < sub > 2.5 < /sub > Exposure
CONCLUSION: While the interrupting effect of SD was not as pronounced as anticipated, this study did validate the effectiveness of SD in modifying health behaviors and minimizing avoidable visits to EDs in addition to curtailing the occurrence of infectious diseases.PMID:38653569 | DOI:10.3349/ymj.2023.0135 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - April 23, 2024 Category: Universities & Medical Training Authors: Minseo Choi Mia Son Sanghyuk Bae Whanhee Lee Kyung-Nam Kim Jung K Hyun Source Type: research
Mechanism of Survivin-mediated neovascularization in ischemic stroke
Asian J Surg. 2024 Apr 22:S1015-9584(24)00746-2. doi: 10.1016/j.asjsur.2024.04.085. Online ahead of print.NO ABSTRACTPMID:38653701 | DOI:10.1016/j.asjsur.2024.04.085 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - April 23, 2024 Category: Surgery Authors: Lingfeng Shu Qinghai Dai Pengcheng Zhu Tao Wu Source Type: research
Selective binding of cationic fibrinogen-mimicking chitosan nanoparticles to activated platelets and efficient drug release for antithrombotic therapy
Int J Biol Macromol. 2024 Apr 21:131742. doi: 10.1016/j.ijbiomac.2024.131742. Online ahead of print.ABSTRACTThrombosis is the main cause of catastrophic events including ischemic stroke, myocardial infarction and pulmonary embolism. Acetylsalicylic acid (ASA) therapy offers a desirable approach to antithrombosis through a reduction of platelet reactivity. However, major bleeding complications, severe off-target side effects, and resistance or nonresponse to ASA greatly attenuate its clinical outcomes. Herein, we report a cationic fibrinogen-mimicking nanoparticle, denoted as ASA-RGD-CS@TPP, to achieve activated-platelet-ta...
Source: International Journal of Biological Macromolecules - April 23, 2024 Category: Biochemistry Authors: Yu Huang Jiahua Wang Yuanyuan Guo Seun Young Park Hongtian Yang Annabelle Lu Yuehua Li Rongjun Chen Source Type: research
Knockdown of lncRNA AU020206 could inhibit microglia apoptosis in ischemic stroke
Cell Mol Biol (Noisy-le-grand). 2024 Mar 31;70(3):142-147. doi: 10.14715/cmb/2024.70.3.21.ABSTRACTThe diagnostic biomarkers associated with ischemic stroke (IS) that may have clinical utility remain elucidated. Thus, the potential functional lncRNAs in IS were explored. The Gene Expression Omnibus database provided the transcriptome profile of IS for download. WGCNA analysis and integrated bioinformatics were used to find genes that were differentially expressed (DEGs). The Starbase database created the lncRNA-based ceRNA network. In order to investigate the molecular mechanism and involved pathways of DEGs in IS, function...
Source: Mol Biol Cell - April 23, 2024 Category: Molecular Biology Authors: Zhihua Chen Wei Hu Jiahong Wang Donggen Rao Jianming Zhu Source Type: research
The resolute Onyx in TIA management (ROTIA)
CONCLUSION: ROTIA demonstrates the feasibility of using the Resolute Onyx drug-eluting stent for the management of TIAs due to refractory ICAD, with high technical success and low peri-procedural complications. Limitations include the retrospective and single-center nature of this study. Future prospective, multi-center, randomized trials with extended observation periods are needed.PMID:38651294 | DOI:10.1177/15910199241249211 (Source: Interventional Neuroradiology)
Source: Interventional Neuroradiology - April 23, 2024 Category: Radiology Authors: Ameer E Hassan Ahmed M Shoman Samantha Miller Abdulrahman Ibrahim Hagrass Sohum Desai Hamzah Saei Wondwossen G Tekle Source Type: research
Relationship Between Hemorrhage Type and Development of Emotional and Behavioral Dyscontrol After Hemorrhagic Stroke
CONCLUSIONS: Patients with ICH and a low GCS score at admission are at increased risk of developing EBD 3 months after hemorrhagic stroke and may benefit from early intervention.PMID:38650464 | DOI:10.1176/appi.neuropsych.20230114 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - April 23, 2024 Category: Psychiatry Authors: Daniel Talmasov Sean Kelly Sarah Ecker Anlys Olivera Aaron Lord Lindsey Gurin Koto Ishida Kara Melmed Jose Torres Cen Zhang Jennifer Frontera Ariane Lewis Source Type: research
Alcohol consumption may be a risk factor for cerebrovascular stenosis in acute ischemic stroke and transient ischemic attack
CONCLUSIONS: Higher alcohol consumption may associate with higher risk and more severity of carotid and cerebrovascular stenosis.PMID:38654185 | DOI:10.1186/s12883-024-03627-x (Source: Atherosclerosis)
Source: Atherosclerosis - April 23, 2024 Category: Cardiology Authors: Yiti Liu Shuo Gu Maoyuan Gou Xiaoyan Guo Source Type: research
Elevated gut microbiota metabolite bile acids confer protective effects on clinical prognosis in ischemic stroke patients
CONCLUSION: Serum TBA is an independent risk factor for disability and poor functional outcomes after AIS or TIA, and exerts a protective effects on brain.PMID:38650617 | PMC:PMC11033300 | DOI:10.3389/fnins.2024.1388748 (Source: Atherosclerosis)
Source: Atherosclerosis - April 23, 2024 Category: Cardiology Authors: Zhaobin Wang Jing Li Yingxin Xu Ye Liu Zhe Zhang Qin Xu Jinxi Lin Yong Jiang Yongjun Wang Jing Jing Anxin Wang Xia Meng Source Type: research
Thrombus composition and regulatory T cell expression are associated with clinical outcomes in acute ischemic stroke patients with thrombectomy
CONCLUSIONS: There was no significant correlation between erythrocyte and fibrin/platelet components in thrombus and functional outcome, but increased expression of regulatory T cells was associated with good functional outcome.PMID:38650441 | DOI:10.3724/zdxbyxb-2023-0424 (Source: Atherosclerosis)
Source: Atherosclerosis - April 23, 2024 Category: Cardiology Authors: Jia Luo Jun Ma Source Type: research
Knockdown of lncRNA AU020206 could inhibit microglia apoptosis in ischemic stroke
Cell Mol Biol (Noisy-le-grand). 2024 Mar 31;70(3):142-147. doi: 10.14715/cmb/2024.70.3.21.ABSTRACTThe diagnostic biomarkers associated with ischemic stroke (IS) that may have clinical utility remain elucidated. Thus, the potential functional lncRNAs in IS were explored. The Gene Expression Omnibus database provided the transcriptome profile of IS for download. WGCNA analysis and integrated bioinformatics were used to find genes that were differentially expressed (DEGs). The Starbase database created the lncRNA-based ceRNA network. In order to investigate the molecular mechanism and involved pathways of DEGs in IS, function...
Source: Cellular and Molecular Biology - April 23, 2024 Category: Molecular Biology Authors: Zhihua Chen Wei Hu Jiahong Wang Donggen Rao Jianming Zhu Source Type: research
Interrupting Effect of Social Distancing on Ischemic Heart Disease, Asthma, Stroke, and Suicide Attempt Patients by PM < sub > 2.5 < /sub > Exposure
CONCLUSION: While the interrupting effect of SD was not as pronounced as anticipated, this study did validate the effectiveness of SD in modifying health behaviors and minimizing avoidable visits to EDs in addition to curtailing the occurrence of infectious diseases.PMID:38653569 | DOI:10.3349/ymj.2023.0135 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - April 23, 2024 Category: Universities & Medical Training Authors: Minseo Choi Mia Son Sanghyuk Bae Whanhee Lee Kyung-Nam Kim Jung K Hyun Source Type: research
