The Diagnostic Challenge of Young-Onset Dementia Syndromes and Primary Psychiatric Diseases: Results From a Retrospective 20-Year Cross-Sectional Study
CONCLUSIONS: Misdiagnosis of younger patients with neurocognitive disorders is not uncommon, especially in cases of bvFTD. Late-onset psychiatric symptoms may be the harbinger to a neurodegenerative disease. Close follow-up and monitoring of these patients are necessary.PMID:34538074 | DOI:10.1176/appi.neuropsych.20100266 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - September 20, 2021 Category: Psychiatry Authors: Paraskevi Tsoukra Dennis Velakoulis Pierre Wibawa Charles B Malpas Mark Walterfang Andrew Evans Sarah Farrand Wendy Kelso Dhamidhu Eratne Samantha M Loi Source Type: research

Traumatic Brain Injury in Children and Adolescents: Psychiatric Disorders 24 Years Later
CONCLUSIONS: Long-term psychiatric outcome (mean=23.92 years [SD=2.17]) in children and adolescents hospitalized for TBI can be predicted at the point of the initial hospitalization encounter by the presence of a preinjury psychiatric disorder and by greater injury severity.PMID:34538075 | DOI:10.1176/appi.neuropsych.20050104 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - September 20, 2021 Category: Psychiatry Authors: Jeffrey E Max Emily A Troyer Hattan Arif Florin Vaida Elisabeth A Wilde Erin D Bigler John R Hesselink Tony T Yang Olga Tymofiyeva Owen Wade Jane S Paulsen Source Type: research

The Diagnostic Challenge of Young-Onset Dementia Syndromes and Primary Psychiatric Diseases: Results From a Retrospective 20-Year Cross-Sectional Study
CONCLUSIONS: Misdiagnosis of younger patients with neurocognitive disorders is not uncommon, especially in cases of bvFTD. Late-onset psychiatric symptoms may be the harbinger to a neurodegenerative disease. Close follow-up and monitoring of these patients are necessary.PMID:34538074 | DOI:10.1176/appi.neuropsych.20100266 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - September 20, 2021 Category: Psychiatry Authors: Paraskevi Tsoukra Dennis Velakoulis Pierre Wibawa Charles B Malpas Mark Walterfang Andrew Evans Sarah Farrand Wendy Kelso Dhamidhu Eratne Samantha M Loi Source Type: research

Traumatic Brain Injury in Children and Adolescents: Psychiatric Disorders 24 Years Later
CONCLUSIONS: Long-term psychiatric outcome (mean=23.92 years [SD=2.17]) in children and adolescents hospitalized for TBI can be predicted at the point of the initial hospitalization encounter by the presence of a preinjury psychiatric disorder and by greater injury severity.PMID:34538075 | DOI:10.1176/appi.neuropsych.20050104 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - September 20, 2021 Category: Psychiatry Authors: Jeffrey E Max Emily A Troyer Hattan Arif Florin Vaida Elisabeth A Wilde Erin D Bigler John R Hesselink Tony T Yang Olga Tymofiyeva Owen Wade Jane S Paulsen Source Type: research

Resting-State Correlations of Fatigue Following Military Deployment
CONCLUSIONS: This exploratory study suggests that mental fatigue in military servicemembers with a history of deployment with at least one mTBI may be related to increased striatal-prefrontal functional connectivity, independent of depression. A finding of effort/reward mismatch may guide future treatment approaches.PMID:34392692 | DOI:10.1176/appi.neuropsych.20100255 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 16, 2021 Category: Psychiatry Authors: Jeffrey D Lewis Kristine M Knutson Stephen J Gotts Michael Tierney Amy Ramage David F Tate Daniel Clauw David A Williams Donald A Robin Eric M Wassermann Source Type: research

Pseudodelirium: Psychiatric Conditions to Consider on the Differential for Delirium
CONCLUSIONS: The clinical presentations of several psychiatric conditions can blend with the phenotype of delirium, at times even co-occurring with it. Detailed evaluation is often required to differentiate such instances of pseudodelirium from delirium proper.PMID:34392693 | DOI:10.1176/appi.neuropsych.20120316 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 16, 2021 Category: Psychiatry Authors: Jo Ellen Wilson Patricia Andrews Aspen Ainsworth Kamalika Roy E Wesley Ely Mark A Oldham Source Type: research

Resting-State Correlations of Fatigue Following Military Deployment
CONCLUSIONS: This exploratory study suggests that mental fatigue in military servicemembers with a history of deployment with at least one mTBI may be related to increased striatal-prefrontal functional connectivity, independent of depression. A finding of effort/reward mismatch may guide future treatment approaches.PMID:34392692 | DOI:10.1176/appi.neuropsych.20100255 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 16, 2021 Category: Psychiatry Authors: Jeffrey D Lewis Kristine M Knutson Stephen J Gotts Michael Tierney Amy Ramage David F Tate Daniel Clauw David A Williams Donald A Robin Eric M Wassermann Source Type: research

Pseudodelirium: Psychiatric Conditions to Consider on the Differential for Delirium
CONCLUSIONS: The clinical presentations of several psychiatric conditions can blend with the phenotype of delirium, at times even co-occurring with it. Detailed evaluation is often required to differentiate such instances of pseudodelirium from delirium proper.PMID:34392693 | DOI:10.1176/appi.neuropsych.20120316 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 16, 2021 Category: Psychiatry Authors: Jo Ellen Wilson Patricia Andrews Aspen Ainsworth Kamalika Roy E Wesley Ely Mark A Oldham Source Type: research

Resting-State Correlations of Fatigue Following Military Deployment
CONCLUSIONS: This exploratory study suggests that mental fatigue in military servicemembers with a history of deployment with at least one mTBI may be related to increased striatal-prefrontal functional connectivity, independent of depression. A finding of effort/reward mismatch may guide future treatment approaches.PMID:34392692 | DOI:10.1176/appi.neuropsych.20100255 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 16, 2021 Category: Psychiatry Authors: Jeffrey D Lewis Kristine M Knutson Stephen J Gotts Michael Tierney Amy Ramage David F Tate Daniel Clauw David A Williams Donald A Robin Eric M Wassermann Source Type: research

Pseudodelirium: Psychiatric Conditions to Consider on the Differential for Delirium
CONCLUSIONS: The clinical presentations of several psychiatric conditions can blend with the phenotype of delirium, at times even co-occurring with it. Detailed evaluation is often required to differentiate such instances of pseudodelirium from delirium proper.PMID:34392693 | DOI:10.1176/appi.neuropsych.20120316 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 16, 2021 Category: Psychiatry Authors: Jo Ellen Wilson Patricia Andrews Aspen Ainsworth Kamalika Roy E Wesley Ely Mark A Oldham Source Type: research

Resting-State Correlations of Fatigue Following Military Deployment
CONCLUSIONS: This exploratory study suggests that mental fatigue in military servicemembers with a history of deployment with at least one mTBI may be related to increased striatal-prefrontal functional connectivity, independent of depression. A finding of effort/reward mismatch may guide future treatment approaches.PMID:34392692 | DOI:10.1176/appi.neuropsych.20100255 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 16, 2021 Category: Psychiatry Authors: Jeffrey D Lewis Kristine M Knutson Stephen J Gotts Michael Tierney Amy Ramage David F Tate Daniel Clauw David A Williams Donald A Robin Eric M Wassermann Source Type: research

Pseudodelirium: Psychiatric Conditions to Consider on the Differential for Delirium
CONCLUSIONS: The clinical presentations of several psychiatric conditions can blend with the phenotype of delirium, at times even co-occurring with it. Detailed evaluation is often required to differentiate such instances of pseudodelirium from delirium proper.PMID:34392693 | DOI:10.1176/appi.neuropsych.20120316 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 16, 2021 Category: Psychiatry Authors: Jo Ellen Wilson Patricia Andrews Aspen Ainsworth Kamalika Roy E Wesley Ely Mark A Oldham Source Type: research

Resting-State Correlations of Fatigue Following Military Deployment
CONCLUSIONS: This exploratory study suggests that mental fatigue in military servicemembers with a history of deployment with at least one mTBI may be related to increased striatal-prefrontal functional connectivity, independent of depression. A finding of effort/reward mismatch may guide future treatment approaches.PMID:34392692 | DOI:10.1176/appi.neuropsych.20100255 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 16, 2021 Category: Psychiatry Authors: Jeffrey D Lewis Kristine M Knutson Stephen J Gotts Michael Tierney Amy Ramage David F Tate Daniel Clauw David A Williams Donald A Robin Eric M Wassermann Source Type: research

Pseudodelirium: Psychiatric Conditions to Consider on the Differential for Delirium
CONCLUSIONS: The clinical presentations of several psychiatric conditions can blend with the phenotype of delirium, at times even co-occurring with it. Detailed evaluation is often required to differentiate such instances of pseudodelirium from delirium proper.PMID:34392693 | DOI:10.1176/appi.neuropsych.20120316 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 16, 2021 Category: Psychiatry Authors: Jo Ellen Wilson Patricia Andrews Aspen Ainsworth Kamalika Roy E Wesley Ely Mark A Oldham Source Type: research

Resting-State Correlations of Fatigue Following Military Deployment
CONCLUSIONS: This exploratory study suggests that mental fatigue in military servicemembers with a history of deployment with at least one mTBI may be related to increased striatal-prefrontal functional connectivity, independent of depression. A finding of effort/reward mismatch may guide future treatment approaches.PMID:34392692 | DOI:10.1176/appi.neuropsych.20100255 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 16, 2021 Category: Psychiatry Authors: Jeffrey D Lewis Kristine M Knutson Stephen J Gotts Michael Tierney Amy Ramage David F Tate Daniel Clauw David A Williams Donald A Robin Eric M Wassermann Source Type: research

Pseudodelirium: Psychiatric Conditions to Consider on the Differential for Delirium
CONCLUSIONS: The clinical presentations of several psychiatric conditions can blend with the phenotype of delirium, at times even co-occurring with it. Detailed evaluation is often required to differentiate such instances of pseudodelirium from delirium proper.PMID:34392693 | DOI:10.1176/appi.neuropsych.20120316 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 16, 2021 Category: Psychiatry Authors: Jo Ellen Wilson Patricia Andrews Aspen Ainsworth Kamalika Roy E Wesley Ely Mark A Oldham Source Type: research

Resting-State Correlations of Fatigue Following Military Deployment
CONCLUSIONS: This exploratory study suggests that mental fatigue in military servicemembers with a history of deployment with at least one mTBI may be related to increased striatal-prefrontal functional connectivity, independent of depression. A finding of effort/reward mismatch may guide future treatment approaches.PMID:34392692 | DOI:10.1176/appi.neuropsych.20100255 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 16, 2021 Category: Psychiatry Authors: Jeffrey D Lewis Kristine M Knutson Stephen J Gotts Michael Tierney Amy Ramage David F Tate Daniel Clauw David A Williams Donald A Robin Eric M Wassermann Source Type: research

Pseudodelirium: Psychiatric Conditions to Consider on the Differential for Delirium
CONCLUSIONS: The clinical presentations of several psychiatric conditions can blend with the phenotype of delirium, at times even co-occurring with it. Detailed evaluation is often required to differentiate such instances of pseudodelirium from delirium proper.PMID:34392693 | DOI:10.1176/appi.neuropsych.20120316 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 16, 2021 Category: Psychiatry Authors: Jo Ellen Wilson Patricia Andrews Aspen Ainsworth Kamalika Roy E Wesley Ely Mark A Oldham Source Type: research

Resting-State Correlations of Fatigue Following Military Deployment
CONCLUSIONS: This exploratory study suggests that mental fatigue in military servicemembers with a history of deployment with at least one mTBI may be related to increased striatal-prefrontal functional connectivity, independent of depression. A finding of effort/reward mismatch may guide future treatment approaches.PMID:34392692 | DOI:10.1176/appi.neuropsych.20100255 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 16, 2021 Category: Psychiatry Authors: Jeffrey D Lewis Kristine M Knutson Stephen J Gotts Michael Tierney Amy Ramage David F Tate Daniel Clauw David A Williams Donald A Robin Eric M Wassermann Source Type: research

Pseudodelirium: Psychiatric Conditions to Consider on the Differential for Delirium
CONCLUSIONS: The clinical presentations of several psychiatric conditions can blend with the phenotype of delirium, at times even co-occurring with it. Detailed evaluation is often required to differentiate such instances of pseudodelirium from delirium proper.PMID:34392693 | DOI:10.1176/appi.neuropsych.20120316 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 16, 2021 Category: Psychiatry Authors: Jo Ellen Wilson Patricia Andrews Aspen Ainsworth Kamalika Roy E Wesley Ely Mark A Oldham Source Type: research

Resting-State Correlations of Fatigue Following Military Deployment
CONCLUSIONS: This exploratory study suggests that mental fatigue in military servicemembers with a history of deployment with at least one mTBI may be related to increased striatal-prefrontal functional connectivity, independent of depression. A finding of effort/reward mismatch may guide future treatment approaches.PMID:34392692 | DOI:10.1176/appi.neuropsych.20100255 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 16, 2021 Category: Psychiatry Authors: Jeffrey D Lewis Kristine M Knutson Stephen J Gotts Michael Tierney Amy Ramage David F Tate Daniel Clauw David A Williams Donald A Robin Eric M Wassermann Source Type: research

Pseudodelirium: Psychiatric Conditions to Consider on the Differential for Delirium
CONCLUSIONS: The clinical presentations of several psychiatric conditions can blend with the phenotype of delirium, at times even co-occurring with it. Detailed evaluation is often required to differentiate such instances of pseudodelirium from delirium proper.PMID:34392693 | DOI:10.1176/appi.neuropsych.20120316 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 16, 2021 Category: Psychiatry Authors: Jo Ellen Wilson Patricia Andrews Aspen Ainsworth Kamalika Roy E Wesley Ely Mark A Oldham Source Type: research

Resting-State Correlations of Fatigue Following Military Deployment
CONCLUSIONS: This exploratory study suggests that mental fatigue in military servicemembers with a history of deployment with at least one mTBI may be related to increased striatal-prefrontal functional connectivity, independent of depression. A finding of effort/reward mismatch may guide future treatment approaches.PMID:34392692 | DOI:10.1176/appi.neuropsych.20100255 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 16, 2021 Category: Psychiatry Authors: Jeffrey D Lewis Kristine M Knutson Stephen J Gotts Michael Tierney Amy Ramage David F Tate Daniel Clauw David A Williams Donald A Robin Eric M Wassermann Source Type: research

Pseudodelirium: Psychiatric Conditions to Consider on the Differential for Delirium
CONCLUSIONS: The clinical presentations of several psychiatric conditions can blend with the phenotype of delirium, at times even co-occurring with it. Detailed evaluation is often required to differentiate such instances of pseudodelirium from delirium proper.PMID:34392693 | DOI:10.1176/appi.neuropsych.20120316 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 16, 2021 Category: Psychiatry Authors: Jo Ellen Wilson Patricia Andrews Aspen Ainsworth Kamalika Roy E Wesley Ely Mark A Oldham Source Type: research

Resting-State Correlations of Fatigue Following Military Deployment
CONCLUSIONS: This exploratory study suggests that mental fatigue in military servicemembers with a history of deployment with at least one mTBI may be related to increased striatal-prefrontal functional connectivity, independent of depression. A finding of effort/reward mismatch may guide future treatment approaches.PMID:34392692 | DOI:10.1176/appi.neuropsych.20100255 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 16, 2021 Category: Psychiatry Authors: Jeffrey D Lewis Kristine M Knutson Stephen J Gotts Michael Tierney Amy Ramage David F Tate Daniel Clauw David A Williams Donald A Robin Eric M Wassermann Source Type: research

Pseudodelirium: Psychiatric Conditions to Consider on the Differential for Delirium
CONCLUSIONS: The clinical presentations of several psychiatric conditions can blend with the phenotype of delirium, at times even co-occurring with it. Detailed evaluation is often required to differentiate such instances of pseudodelirium from delirium proper.PMID:34392693 | DOI:10.1176/appi.neuropsych.20120316 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 16, 2021 Category: Psychiatry Authors: Jo Ellen Wilson Patricia Andrews Aspen Ainsworth Kamalika Roy E Wesley Ely Mark A Oldham Source Type: research

Resting-State Correlations of Fatigue Following Military Deployment
CONCLUSIONS: This exploratory study suggests that mental fatigue in military servicemembers with a history of deployment with at least one mTBI may be related to increased striatal-prefrontal functional connectivity, independent of depression. A finding of effort/reward mismatch may guide future treatment approaches.PMID:34392692 | DOI:10.1176/appi.neuropsych.20100255 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 16, 2021 Category: Psychiatry Authors: Jeffrey D Lewis Kristine M Knutson Stephen J Gotts Michael Tierney Amy Ramage David F Tate Daniel Clauw David A Williams Donald A Robin Eric M Wassermann Source Type: research

Pseudodelirium: Psychiatric Conditions to Consider on the Differential for Delirium
CONCLUSIONS: The clinical presentations of several psychiatric conditions can blend with the phenotype of delirium, at times even co-occurring with it. Detailed evaluation is often required to differentiate such instances of pseudodelirium from delirium proper.PMID:34392693 | DOI:10.1176/appi.neuropsych.20120316 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 16, 2021 Category: Psychiatry Authors: Jo Ellen Wilson Patricia Andrews Aspen Ainsworth Kamalika Roy E Wesley Ely Mark A Oldham Source Type: research

Resting-State Correlations of Fatigue Following Military Deployment
CONCLUSIONS: This exploratory study suggests that mental fatigue in military servicemembers with a history of deployment with at least one mTBI may be related to increased striatal-prefrontal functional connectivity, independent of depression. A finding of effort/reward mismatch may guide future treatment approaches.PMID:34392692 | DOI:10.1176/appi.neuropsych.20100255 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 16, 2021 Category: Psychiatry Authors: Jeffrey D Lewis Kristine M Knutson Stephen J Gotts Michael Tierney Amy Ramage David F Tate Daniel Clauw David A Williams Donald A Robin Eric M Wassermann Source Type: research

Pseudodelirium: Psychiatric Conditions to Consider on the Differential for Delirium
CONCLUSIONS: The clinical presentations of several psychiatric conditions can blend with the phenotype of delirium, at times even co-occurring with it. Detailed evaluation is often required to differentiate such instances of pseudodelirium from delirium proper.PMID:34392693 | DOI:10.1176/appi.neuropsych.20120316 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 16, 2021 Category: Psychiatry Authors: Jo Ellen Wilson Patricia Andrews Aspen Ainsworth Kamalika Roy E Wesley Ely Mark A Oldham Source Type: research

Resting-State Correlations of Fatigue Following Military Deployment
CONCLUSIONS: This exploratory study suggests that mental fatigue in military servicemembers with a history of deployment with at least one mTBI may be related to increased striatal-prefrontal functional connectivity, independent of depression. A finding of effort/reward mismatch may guide future treatment approaches.PMID:34392692 | DOI:10.1176/appi.neuropsych.20100255 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 16, 2021 Category: Psychiatry Authors: Jeffrey D Lewis Kristine M Knutson Stephen J Gotts Michael Tierney Amy Ramage David F Tate Daniel Clauw David A Williams Donald A Robin Eric M Wassermann Source Type: research

Pseudodelirium: Psychiatric Conditions to Consider on the Differential for Delirium
CONCLUSIONS: The clinical presentations of several psychiatric conditions can blend with the phenotype of delirium, at times even co-occurring with it. Detailed evaluation is often required to differentiate such instances of pseudodelirium from delirium proper.PMID:34392693 | DOI:10.1176/appi.neuropsych.20120316 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 16, 2021 Category: Psychiatry Authors: Jo Ellen Wilson Patricia Andrews Aspen Ainsworth Kamalika Roy E Wesley Ely Mark A Oldham Source Type: research

Resting-State Correlations of Fatigue Following Military Deployment
CONCLUSIONS: This exploratory study suggests that mental fatigue in military servicemembers with a history of deployment with at least one mTBI may be related to increased striatal-prefrontal functional connectivity, independent of depression. A finding of effort/reward mismatch may guide future treatment approaches.PMID:34392692 | DOI:10.1176/appi.neuropsych.20100255 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 16, 2021 Category: Psychiatry Authors: Jeffrey D Lewis Kristine M Knutson Stephen J Gotts Michael Tierney Amy Ramage David F Tate Daniel Clauw David A Williams Donald A Robin Eric M Wassermann Source Type: research

Pseudodelirium: Psychiatric Conditions to Consider on the Differential for Delirium
CONCLUSIONS: The clinical presentations of several psychiatric conditions can blend with the phenotype of delirium, at times even co-occurring with it. Detailed evaluation is often required to differentiate such instances of pseudodelirium from delirium proper.PMID:34392693 | DOI:10.1176/appi.neuropsych.20120316 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 16, 2021 Category: Psychiatry Authors: Jo Ellen Wilson Patricia Andrews Aspen Ainsworth Kamalika Roy E Wesley Ely Mark A Oldham Source Type: research

Cognitive Dysfunction in White Matter Disorders: New Perspectives in Treatment and Recovery
J Neuropsychiatry Clin Neurosci. 2021 Aug 3:appineuropsych21030080. doi: 10.1176/appi.neuropsych.21030080. Online ahead of print.ABSTRACTWhite matter disorders are increasingly appreciated as capable of disrupting cognitive function, and this impairment may be sufficiently severe to produce the syndrome of white matter dementia. Although recognizing this problem is important for diagnostic accuracy, the treatment of cognitive dysfunction and dementia in the white matter disorders has received relatively little attention. Similarly, few data are available regarding the potential for cognitive recovery in these disorders. Re...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 3, 2021 Category: Psychiatry Authors: Christopher M Filley Source Type: research

A Phase-2 Pilot Study of a Therapeutic Combination of Δ < sup > 9 < /sup > -Tetrahydracannabinol and Palmitoylethanolamide for Adults With Tourette's Syndrome
CONCLUSIONS: Although the initial data from this trial in adults with refractory Tourette's syndrome are promising, future randomized double-blind placebo-controlled trials are necessary to demonstrate efficacy of THX-110 treatment. The challenges raised by the difficulty in blinding trials due to the psychoactive properties of many cannabis-derived compounds need to be further appreciated in these trial designs.PMID:34340527 | DOI:10.1176/appi.neuropsych.19080178 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 3, 2021 Category: Psychiatry Authors: Michael H Bloch Angeli Landeros-Weisenberger Jessica A Johnson James F Leckman Source Type: research

Cognitive Dysfunction in White Matter Disorders: New Perspectives in Treatment and Recovery
J Neuropsychiatry Clin Neurosci. 2021 Aug 3:appineuropsych21030080. doi: 10.1176/appi.neuropsych.21030080. Online ahead of print.ABSTRACTWhite matter disorders are increasingly appreciated as capable of disrupting cognitive function, and this impairment may be sufficiently severe to produce the syndrome of white matter dementia. Although recognizing this problem is important for diagnostic accuracy, the treatment of cognitive dysfunction and dementia in the white matter disorders has received relatively little attention. Similarly, few data are available regarding the potential for cognitive recovery in these disorders. Re...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 3, 2021 Category: Psychiatry Authors: Christopher M Filley Source Type: research

A Phase-2 Pilot Study of a Therapeutic Combination of Δ < sup > 9 < /sup > -Tetrahydracannabinol and Palmitoylethanolamide for Adults With Tourette's Syndrome
CONCLUSIONS: Although the initial data from this trial in adults with refractory Tourette's syndrome are promising, future randomized double-blind placebo-controlled trials are necessary to demonstrate efficacy of THX-110 treatment. The challenges raised by the difficulty in blinding trials due to the psychoactive properties of many cannabis-derived compounds need to be further appreciated in these trial designs.PMID:34340527 | DOI:10.1176/appi.neuropsych.19080178 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 3, 2021 Category: Psychiatry Authors: Michael H Bloch Angeli Landeros-Weisenberger Jessica A Johnson James F Leckman Source Type: research

Cognitive Dysfunction in White Matter Disorders: New Perspectives in Treatment and Recovery
J Neuropsychiatry Clin Neurosci. 2021 Aug 3:appineuropsych21030080. doi: 10.1176/appi.neuropsych.21030080. Online ahead of print.ABSTRACTWhite matter disorders are increasingly appreciated as capable of disrupting cognitive function, and this impairment may be sufficiently severe to produce the syndrome of white matter dementia. Although recognizing this problem is important for diagnostic accuracy, the treatment of cognitive dysfunction and dementia in the white matter disorders has received relatively little attention. Similarly, few data are available regarding the potential for cognitive recovery in these disorders. Re...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 3, 2021 Category: Psychiatry Authors: Christopher M Filley Source Type: research

A Phase-2 Pilot Study of a Therapeutic Combination of Δ < sup > 9 < /sup > -Tetrahydracannabinol and Palmitoylethanolamide for Adults With Tourette's Syndrome
CONCLUSIONS: Although the initial data from this trial in adults with refractory Tourette's syndrome are promising, future randomized double-blind placebo-controlled trials are necessary to demonstrate efficacy of THX-110 treatment. The challenges raised by the difficulty in blinding trials due to the psychoactive properties of many cannabis-derived compounds need to be further appreciated in these trial designs.PMID:34340527 | DOI:10.1176/appi.neuropsych.19080178 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 3, 2021 Category: Psychiatry Authors: Michael H Bloch Angeli Landeros-Weisenberger Jessica A Johnson James F Leckman Source Type: research

Cognitive Dysfunction in White Matter Disorders: New Perspectives in Treatment and Recovery
J Neuropsychiatry Clin Neurosci. 2021 Aug 3:appineuropsych21030080. doi: 10.1176/appi.neuropsych.21030080. Online ahead of print.ABSTRACTWhite matter disorders are increasingly appreciated as capable of disrupting cognitive function, and this impairment may be sufficiently severe to produce the syndrome of white matter dementia. Although recognizing this problem is important for diagnostic accuracy, the treatment of cognitive dysfunction and dementia in the white matter disorders has received relatively little attention. Similarly, few data are available regarding the potential for cognitive recovery in these disorders. Re...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 3, 2021 Category: Psychiatry Authors: Christopher M Filley Source Type: research

A Phase-2 Pilot Study of a Therapeutic Combination of Δ < sup > 9 < /sup > -Tetrahydracannabinol and Palmitoylethanolamide for Adults With Tourette's Syndrome
CONCLUSIONS: Although the initial data from this trial in adults with refractory Tourette's syndrome are promising, future randomized double-blind placebo-controlled trials are necessary to demonstrate efficacy of THX-110 treatment. The challenges raised by the difficulty in blinding trials due to the psychoactive properties of many cannabis-derived compounds need to be further appreciated in these trial designs.PMID:34340527 | DOI:10.1176/appi.neuropsych.19080178 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 3, 2021 Category: Psychiatry Authors: Michael H Bloch Angeli Landeros-Weisenberger Jessica A Johnson James F Leckman Source Type: research

Cognitive Dysfunction in White Matter Disorders: New Perspectives in Treatment and Recovery
J Neuropsychiatry Clin Neurosci. 2021 Aug 3:appineuropsych21030080. doi: 10.1176/appi.neuropsych.21030080. Online ahead of print.ABSTRACTWhite matter disorders are increasingly appreciated as capable of disrupting cognitive function, and this impairment may be sufficiently severe to produce the syndrome of white matter dementia. Although recognizing this problem is important for diagnostic accuracy, the treatment of cognitive dysfunction and dementia in the white matter disorders has received relatively little attention. Similarly, few data are available regarding the potential for cognitive recovery in these disorders. Re...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 3, 2021 Category: Psychiatry Authors: Christopher M Filley Source Type: research

A Phase-2 Pilot Study of a Therapeutic Combination of Δ < sup > 9 < /sup > -Tetrahydracannabinol and Palmitoylethanolamide for Adults With Tourette's Syndrome
CONCLUSIONS: Although the initial data from this trial in adults with refractory Tourette's syndrome are promising, future randomized double-blind placebo-controlled trials are necessary to demonstrate efficacy of THX-110 treatment. The challenges raised by the difficulty in blinding trials due to the psychoactive properties of many cannabis-derived compounds need to be further appreciated in these trial designs.PMID:34340527 | DOI:10.1176/appi.neuropsych.19080178 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 3, 2021 Category: Psychiatry Authors: Michael H Bloch Angeli Landeros-Weisenberger Jessica A Johnson James F Leckman Source Type: research

Cognitive Dysfunction in White Matter Disorders: New Perspectives in Treatment and Recovery
J Neuropsychiatry Clin Neurosci. 2021 Aug 3:appineuropsych21030080. doi: 10.1176/appi.neuropsych.21030080. Online ahead of print.ABSTRACTWhite matter disorders are increasingly appreciated as capable of disrupting cognitive function, and this impairment may be sufficiently severe to produce the syndrome of white matter dementia. Although recognizing this problem is important for diagnostic accuracy, the treatment of cognitive dysfunction and dementia in the white matter disorders has received relatively little attention. Similarly, few data are available regarding the potential for cognitive recovery in these disorders. Re...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 3, 2021 Category: Psychiatry Authors: Christopher M Filley Source Type: research

A Phase-2 Pilot Study of a Therapeutic Combination of Δ < sup > 9 < /sup > -Tetrahydracannabinol and Palmitoylethanolamide for Adults With Tourette's Syndrome
CONCLUSIONS: Although the initial data from this trial in adults with refractory Tourette's syndrome are promising, future randomized double-blind placebo-controlled trials are necessary to demonstrate efficacy of THX-110 treatment. The challenges raised by the difficulty in blinding trials due to the psychoactive properties of many cannabis-derived compounds need to be further appreciated in these trial designs.PMID:34340527 | DOI:10.1176/appi.neuropsych.19080178 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 3, 2021 Category: Psychiatry Authors: Michael H Bloch Angeli Landeros-Weisenberger Jessica A Johnson James F Leckman Source Type: research

Cognitive Dysfunction in White Matter Disorders: New Perspectives in Treatment and Recovery
J Neuropsychiatry Clin Neurosci. 2021 Aug 3:appineuropsych21030080. doi: 10.1176/appi.neuropsych.21030080. Online ahead of print.ABSTRACTWhite matter disorders are increasingly appreciated as capable of disrupting cognitive function, and this impairment may be sufficiently severe to produce the syndrome of white matter dementia. Although recognizing this problem is important for diagnostic accuracy, the treatment of cognitive dysfunction and dementia in the white matter disorders has received relatively little attention. Similarly, few data are available regarding the potential for cognitive recovery in these disorders. Re...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 3, 2021 Category: Psychiatry Authors: Christopher M Filley Source Type: research

A Phase-2 Pilot Study of a Therapeutic Combination of Δ < sup > 9 < /sup > -Tetrahydracannabinol and Palmitoylethanolamide for Adults With Tourette's Syndrome
CONCLUSIONS: Although the initial data from this trial in adults with refractory Tourette's syndrome are promising, future randomized double-blind placebo-controlled trials are necessary to demonstrate efficacy of THX-110 treatment. The challenges raised by the difficulty in blinding trials due to the psychoactive properties of many cannabis-derived compounds need to be further appreciated in these trial designs.PMID:34340527 | DOI:10.1176/appi.neuropsych.19080178 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 3, 2021 Category: Psychiatry Authors: Michael H Bloch Angeli Landeros-Weisenberger Jessica A Johnson James F Leckman Source Type: research

Cognitive Dysfunction in White Matter Disorders: New Perspectives in Treatment and Recovery
J Neuropsychiatry Clin Neurosci. 2021 Aug 3:appineuropsych21030080. doi: 10.1176/appi.neuropsych.21030080. Online ahead of print.ABSTRACTWhite matter disorders are increasingly appreciated as capable of disrupting cognitive function, and this impairment may be sufficiently severe to produce the syndrome of white matter dementia. Although recognizing this problem is important for diagnostic accuracy, the treatment of cognitive dysfunction and dementia in the white matter disorders has received relatively little attention. Similarly, few data are available regarding the potential for cognitive recovery in these disorders. Re...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 3, 2021 Category: Psychiatry Authors: Christopher M Filley Source Type: research

A Phase-2 Pilot Study of a Therapeutic Combination of Δ < sup > 9 < /sup > -Tetrahydracannabinol and Palmitoylethanolamide for Adults With Tourette's Syndrome
CONCLUSIONS: Although the initial data from this trial in adults with refractory Tourette's syndrome are promising, future randomized double-blind placebo-controlled trials are necessary to demonstrate efficacy of THX-110 treatment. The challenges raised by the difficulty in blinding trials due to the psychoactive properties of many cannabis-derived compounds need to be further appreciated in these trial designs.PMID:34340527 | DOI:10.1176/appi.neuropsych.19080178 (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 3, 2021 Category: Psychiatry Authors: Michael H Bloch Angeli Landeros-Weisenberger Jessica A Johnson James F Leckman Source Type: research