Inflammatory Bowel Disease Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Protein-losing enteropathy: is it Crohn's disease?
Rev Esp Enferm Dig. 2024 Apr 30. doi: 10.17235/reed.2024.10461/2024. Online ahead of print.ABSTRACTCase of a 24-year-old woman presenting due to edema in lower extremities. The patient had had infectious mononucleosis three weeks prior and had medical history of suspicion of Crohn's disease (CD) (due to a non-specific ileocolitis in a colonoscopy/EnteroRM). No ongoing medication. Laboratory evaluation unveiled hypoproteinemia with severe hypoalbuminemia, no renal abnormalities. A PLE was assumed, with post-infectious or CD being the most likely culprits. Alternative causes were extensively excluded. A videocapsule revealed...
Source: Revista Espanola de Enfermedades Digestivas - April 30, 2024 Category: Gastroenterology Authors: Maria Jos é Temido Sandra Lopes Pedro Figueiredo Francisco Portela Source Type: research

Sacroiliitis in inflammatory bowel disease on abdominal computed tomography: prevalence, misses, and associated factors
CONCLUSION: Physicians should carefully evaluate SI joints on abdominal CT in patients with IBD to enable early detection of sacroiliitis, potentially leading to an early diagnosis of axSpA. In addition, if patients with IBD present with back pain, the possibility of sacroiliitis should be considered.PMID:38686835 | DOI:10.1080/03009742.2024.2337453 (Source: Scandinavian Journal of Rheumatology)
Source: Scandinavian Journal of Rheumatology - April 30, 2024 Category: Rheumatology Authors: D K Kim K-C Lee J K Kim Source Type: research

TLR7-dependent eosinophil degranulation links psoriatic skin inflammation to small intestinal inflammatory changes in mice
Exp Mol Med. 2024 May 1. doi: 10.1038/s12276-024-01225-y. Online ahead of print.ABSTRACTRecent evidence of gut microbiota dysbiosis in the context of psoriasis and the increased cooccurrence of inflammatory bowel disease and psoriasis suggest a close relationship between skin and gut immune responses. Using a mouse model of psoriasis induced by the Toll-like receptor (TLR) 7 ligand imiquimod, we found that psoriatic dermatitis was accompanied by inflammatory changes in the small intestine associated with eosinophil degranulation, which impaired intestinal barrier integrity. Inflammatory responses in the skin and small inte...
Source: Molecular Medicine - April 30, 2024 Category: Molecular Biology Authors: Hee Joo Kim Jinsun Jang Kunhee Na Eun-Hui Lee Hyeon-Jung Gu Yoon Hee Lim Seul-A Joo Seung Eun Baek Joo-Young Roh Han-Joo Maeng Yun Hak Kim Young-Jae Lee Byung-Chul Oh YunJae Jung Source Type: research

Latent profiles of fatigue in inflammatory bowel disease
This study aimed to identify fatigue profiles or clusters... (Source: BMC Gastroenterology)
Source: BMC Gastroenterology - April 30, 2024 Category: Gastroenterology Authors: Alex Barnes, Barbara Toson, R. V. Bryant, Sutapa Mukherjee, Jane M. Andrews, Paul Spizzo and R éme Mountifield Tags: Research Source Type: research

Combination treatment of inflammatory bowel disease: Present status and future perspectives
World J Gastroenterol. 2024 Apr 21;30(15):2068-2080. doi: 10.3748/wjg.v30.i15.2068.ABSTRACTThe treatment of patients with inflammatory bowel disease (IBD), especially those with severe or refractory disease, represents an important challenge for the clinical gastroenterologist. It seems to be no exaggeration to say that in these patients, not only the scientific background of the gastroenterologist is tested, but also the abundance of "gifts" that he should possess (insight, intuition, determination, ability to take initiative, etc.) for the successful outcome of the treatment. In daily clinical practice, depending on the ...
Source: World Journal of Gastroenterology : WJG - April 29, 2024 Category: Gastroenterology Authors: John K Triantafillidis Constantinos G Zografos Manousos M Konstadoulakis Apostolos E Papalois Source Type: research

Topic highlight on texture and color enhancement imaging in gastrointestinal diseases
In conclusion, TXI can improve gastrointestinal lesion detection and qualitative diagnosis. Therefore, further studies on the efficacy of TXI in clinical practice are required.PMID:38681121 | PMC:PMC11045492 | DOI:10.3748/wjg.v30.i14.1934 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 29, 2024 Category: Gastroenterology Authors: Osamu Toyoshima Toshihiro Nishizawa Keisuke Hata Source Type: research

Acute interstitial nephritis in patients with inflammatory bowel disease treated with vedolizumab: a systematic review
CONCLUSION: Our findings suggest that vedolizumab, although rarely, could cause AIN in patients with IBD. Awareness of laboratory findings and symptoms consistent with AIN, along with monitoring of the kidney function, could be warranted in patients with IBD treated with vedolizumab.PMID:38682791 | DOI:10.1080/00365521.2024.2345383 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - April 29, 2024 Category: Gastroenterology Authors: Anders Forss Paulina Flis Adonis Sotoodeh Marjo Kapraali Staffan Rosenborg Source Type: research

Dissecting the Mechanisms of Intestinal Immune Homeostasis by Analyzing T-Cell Immune Response in Crohn's Disease and Colorectal Cancer
CONCLUSION: Finally, the analysis of regulon networks revealed several promising candidates for cell-specific transcription factors (TFs). This study focused on the immune molecular mechanism under intestinal diseases. It contributed to the novel insight of depicting a detailed immune landscape and revealing T-cell responding mechanisms in CD and CRC.PMID:38682449 | DOI:10.2174/0115665232294568240201073417 (Source: Current Gene Therapy)
Source: Current Gene Therapy - April 29, 2024 Category: Genetics & Stem Cells Authors: Tianming Jiang Jie Zheng Nana Li Xiaodong Li Jixing He Junde Zhou Boshi Sun Qiang Chi Source Type: research

Probiotics: Shaping the gut immunological responses
World J Gastroenterol. 2024 Apr 21;30(15):2096-2108. doi: 10.3748/wjg.v30.i15.2096.ABSTRACTProbiotics are live microorganisms exerting beneficial effects on the host's health when administered in adequate amounts. Among the most popular and adequately studied probiotics are bacteria from the families Lactobacillaceae, Bifidobacteriaceae and yeasts. Most of them have been shown, both in vitro and in vivo studies of intestinal inflammation models, to provide favorable results by means of improving the gut microbiota composition, promoting the wound healing process and shaping the immunological responses. Chronic intestinal c...
Source: World Journal of Gastroenterology : WJG - April 29, 2024 Category: Gastroenterology Authors: Eirini Filidou Leonidas Kandilogiannakis Anne Shrewsbury George Kolios Katerina Kotzampassi Source Type: research

Understanding autoimmune pancreatitis: Clinical features, management challenges, and association with malignancies
World J Gastroenterol. 2024 Apr 21;30(15):2091-2095. doi: 10.3748/wjg.v30.i15.2091.ABSTRACTIn this editorial we comment on the article by Jaber et al. Autoimmune pancreatitis (AIP) represents a distinct form of pancreatitis, categorized into AIP-1 and AIP-2, characterized by obstructive jaundice, lymphoplasmacytic infiltrate, and fibrosis. AIP-1, associated with elevated immunoglobulin G4 (IgG4) levels, exhibits higher relapse rates, affecting older males, while AIP-2 is less common and linked to inflammatory bowel disease. AIP is considered a manifestation of IgG4-related systemic disease, sharing characteristic histologi...
Source: World Journal of Gastroenterology : WJG - April 29, 2024 Category: Gastroenterology Authors: Grigorios Christodoulidis Marina Nektaria Kouliou Konstantinos Eleftherios Koumarelas Source Type: research

Cardiovascular Comorbidities and Inflammatory Bowel Disease: Causes and Consequences
This article discusses causes of CVD in IBD and strategies to modify the consequences.PMID:38682122 | PMC:PMC11047149 (Source: Atherosclerosis)
Source: Atherosclerosis - April 29, 2024 Category: Cardiology Authors: Preetika Sinh Raymond K Cross Source Type: research

Methionine-choline deficient diet deteriorates DSS-induced murine colitis through disturbance of gut microbes and infiltration of macrophages
In conclusion, this study supports the concept that intake of MCD predisposes to experimental colitis and enhances its pathogenesis via modulating gut microbes and macrophages in mice.PMID:38684800 | DOI:10.1038/s41401-024-01291-y (Source: Acta Pharmacologica Sinica)
Source: Acta Pharmacologica Sinica - April 29, 2024 Category: Drugs & Pharmacology Authors: Mo-Ting Liu Yao Zhang Cai-Gui Xiang Tao Yang Xiao-Han Wang Qiu-Kai Lu Hui-Min Lu Chen Fan Chun-Lan Feng Xiao-Qian Yang Duo-Wu Zou Heng Li Wei Tang Source Type: research