Pulmonary congestion in patients with pulmonary arterial hypertension? New insights from lung ultrasound
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - April 29, 2024 Category: Cardiology Authors: Elke Platz, David Systrom, Jane A. Leopold Tags: Invited Editorial Source Type: research

Role of antihypertensive medicines in prostate cancer: a systematic review
Hypertension is associated with the risk of prostate cancer (PCa) and its progression, however, it remains unclear whether antihypertensive medicines alter PCa risk or prognosis. This systematic review evaluat... (Source: BMC Cancer)
Source: BMC Cancer - April 29, 2024 Category: Cancer & Oncology Authors: Chinonyerem O. Iheanacho and Okechukwu Harrison Enechukwu Tags: Research Source Type: research

Risk of Adverse Cardiovascular Outcomes in Postmenopausal Women with Inflammatory Bowel Disease
ConclusionsAmong postmenopausal women with IBD, risk of ischemic stroke may be higher than in non-IBD women. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 29, 2024 Category: Gastroenterology Source Type: research

Indicators of Dietary Behavior and Physical Activity Change Associated with Metabolic Control of Obesity, Hypertension, and Type 2 Diabetes Mellitus in Mexican Adults: National Nutrition and Health Survey in Mexico, 2016
Metabolic Syndrome and Related Disorders, Ahead of Print. (Source: Metabolic Syndrome and Related Disorders)
Source: Metabolic Syndrome and Related Disorders - April 29, 2024 Category: Endocrinology Authors: Juan Espinosa-Montero Eric Monterrubio-Flores Manuel Aguilar-Tamayo Nayeli Mac ías-Morales Mario Sanchez-Dominguez Ismael Campos-Nonato Source Type: research

Recurrence of Pulmonary Arteriovenous Malformation after Embolization in Patients with Pulmonary Hypertension
To evaluate the correlation between pulmonary hypertension (PH) and post-embolization pulmonary arteriovenous malformation (PAVM) recurrence. (Source: Journal of Vascular and Interventional Radiology : JVIR)
Source: Journal of Vascular and Interventional Radiology : JVIR - April 29, 2024 Category: Radiology Authors: Adam Fish, Daniel Wang, Elizabeth Knight, Jeffrey Pollak, Todd Schlachter Tags: Clinical Study Source Type: research

Association between the severity of hard-to-treat psoriasis and the prevalence of metabolic syndrome: A hospital-based cross-sectional study in Jakarta, Indonesia
This study found most frequent components of MetS were abdominal obesity, decreased levels of HDL cholesterol, hypertension, hyperglycemia, and hypertriglyceridemia respectively. Individuals with severe hard-to-treat psoriasis had a 3.67 times more likely to have MetS rather than the mild-moderate group. (Source: PLoS One)
Source: PLoS One - April 29, 2024 Category: Biomedical Science Authors: Dina Evyana Source Type: research

Evaluation of the early use of norepinephrine in major abdominal surgery on medical and surgical postoperative complications: study protocol for a randomised controlled trial (EPON STUDY)
This study aims to assess the benefit of norepinephrine versus ephedrine at the induction of anaesthesia to prevent postoperative complications following major abdominal surgery by preventing IOH. Methods and analysis The EPON STUDY is a prospective single-centre randomised controlled trial with the planned inclusion of 500 patients scheduled for major abdominal surgery at the Amiens University Hospital. The inclusion criteria are patients aged over 50 years weighing more than 50 kg with an American Society of Anesthesiologists physical status score of ≥2 undergoing major abdominal surgery under general anaesthesia. Pa...
Source: BMJ Open - April 29, 2024 Category: General Medicine Authors: Trocheris-Fumery, O., Scetbon, C., Flet, T., Meynier, J., Sellier, M., Rumbach, M., Badaoui, R., Villeret, L., Tarpin, P., Abou-Arab, O., Bar, S., Dupont, H. Tags: Open access, Anaesthesia Source Type: research

Lifetime costs of alcohol consumption in Thailand: protocol for an incidence-based cost-of-illness study using Markov model
Introduction Several prevalence-based cost-of-illness (COI) studies have been conducted to estimate the economic burden of alcohol consumption borne by a particular society in a given year. Yet there are few studies examining the economic costs incurred by an individual drinker over his/her lifetime. Thus, this study aims to estimate the costs incurred by an individual drinker’s alcohol consumption over his or her lifetime in Thailand. Methods and analysis An incidence-based COI approach will be employed. To project individuals’ associated costs over a lifetime, a Markov modelling technique will be used. The f...
Source: BMJ Open - April 29, 2024 Category: General Medicine Authors: Luangsinsiri, C., Thavorncharoensap, M., Chaikledkaew, U., Pattanaprateep, O., Sornpaisarn, B., Rehm, J. Tags: Open access, Health economics Source Type: research

Hypertension, depression, and health-related quality of life among hospitalized patients in Afghanistan
Journal of Human Hypertension, Published online: 29 April 2024; doi:10.1038/s41371-024-00914-5Hypertension, depression, and health-related quality of life among hospitalized patients in Afghanistan (Source: Journal of Human Hypertension)
Source: Journal of Human Hypertension - April 29, 2024 Category: Cardiology Authors: Ahmad Neyazi Abdul Qadim Mohammadi Mehrab Neyazi Shashank Timilsina Bijaya Kumar Padhi Mark D. Griffiths Source Type: research

Fennel seeds extract prevents fructose-induced cardiac dysfunction in a rat model of metabolic syndrome via targeting abdominal obesity, hyperuricemia and NF- κβ inflammatory pathway
CONCLUSION: Findings could suggest FSE as a complementary supplement for preventing MetS and associated cardiac outcomes. However, well controlled clinical studies are still needed.PMID:38678740 | DOI:10.1016/j.tice.2024.102385 (Source: Tissue and Cell)
Source: Tissue and Cell - April 28, 2024 Category: Cytology Authors: Azza Mohamad El-Wakf Mamdouh Rashad El-Sawi Hadeer Mahmoud El-Nigomy Eman Mohamad El-Nashar Norah Saeed Al-Zahrani Nasser G Alqahtani Rashid A Aldahhan Zienab Helmy Eldken Source Type: research

Plasma levels of Sirtuin 7 are decreased in patients with essential hypertension
CONCLUSION: Plasma levels of SIRT7 are decreased in patients with essential hypertension, implying its potential as a biomarker for diagnosing essential hypertension..PMID:38679273 | DOI:10.1016/j.clinbiochem.2024.110766 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - April 28, 2024 Category: Biochemistry Authors: Ying Liu Ying Guo Ning Wang Zhaojie Dong Xiaoyan Yang Qian Liu Guohong Wang Mingzhao Qin Jiawei Song Jing Li Li Xu Ying Dong Jiuchang Zhong Source Type: research

Antihypertensive treatment during pregnancy induces long-term changes in gut microbiota and the behaviors of the attention deficit hyperactivity disorder offspring
Toxicol Appl Pharmacol. 2024 Apr 26:116946. doi: 10.1016/j.taap.2024.116946. Online ahead of print.ABSTRACTThe pathogenesis of attention-deficit/hyperactivity disorder (ADHD) has not been fully elucidated. Gestational hypertension could double the probability of ADHD in the offspring, while the initial bacterial communication between the mother and offspring has been associated with psychiatric disorders. Thus, we hypothesize that antihypertensive treatment during pregnancy may abate the impairments in neurodevelopment of the offspring. To test this hypothesis, we chose Captopril and Labetalol, to apply to pregnant spontan...
Source: Toxicology and Applied Pharmacology - April 28, 2024 Category: Toxicology Authors: Hong-Bao Li Meng-Lu Xu Wen-Jie Xia Yuan-Yuan Dong Bo Peng Qing Su Xiao-Min Wang Jia-Yue Yu Ya-Nan Gao Jun-Zhe Wu Meng-Yue Xu Jin-Bao Yang Zhi-Ming Dai Lei Chen Ying Li Juan Bai Source Type: research

Fennel seeds extract prevents fructose-induced cardiac dysfunction in a rat model of metabolic syndrome via targeting abdominal obesity, hyperuricemia and NF- κβ inflammatory pathway
CONCLUSION: Findings could suggest FSE as a complementary supplement for preventing MetS and associated cardiac outcomes. However, well controlled clinical studies are still needed.PMID:38678740 | DOI:10.1016/j.tice.2024.102385 (Source: Tissue and Cell)
Source: Tissue and Cell - April 28, 2024 Category: Cytology Authors: Azza Mohamad El-Wakf Mamdouh Rashad El-Sawi Hadeer Mahmoud El-Nigomy Eman Mohamad El-Nashar Norah Saeed Al-Zahrani Nasser G Alqahtani Rashid A Aldahhan Zienab Helmy Eldken Source Type: research

Plasma levels of Sirtuin 7 are decreased in patients with essential hypertension
CONCLUSION: Plasma levels of SIRT7 are decreased in patients with essential hypertension, implying its potential as a biomarker for diagnosing essential hypertension.PMID:38679273 | DOI:10.1016/j.clinbiochem.2024.110766 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - April 28, 2024 Category: Biochemistry Authors: Ying Liu Ying Guo Ning Wang Zhaojie Dong Xiaoyan Yang Qian Liu Guohong Wang Mingzhao Qin Jiawei Song Jing Li Li Xu Ying Dong Jiuchang Zhong Source Type: research

Renal macrophages induce hypertension and kidney fibrosis in Angiotensin II salt mice model
This study aimed to determine the effects of angiotensin II (Ang II) salt-induced hypertension on renal immune cells and to determine whether renal macrophages are involved in the induction of hypertension. Hypertension was induced by administration of Ang II and saline for two weeks. The effects of hypertension on kidney immune cells were assessed using flow cytometry. Macrophage infiltration in the kidney was assessed by immunohistochemistry and kidney fibrosis was assessed using trichrome stain and kidney real time-qPCR. Liposome encapsulated clodronate was used to deplete macrophages in C57BL/6J mice and investigate th...
Source: Biochemical and Biophysical Research communications - April 28, 2024 Category: Biochemistry Authors: Joseph Kasyoki Peter Ryusuke Umene Chia-Hsien Wu Yasuna Nakamura Norito Washimine Ryoko Yamamoto Caroline Ngugi Kavoo Linge Joseph K Kweri Tsuyoshi Inoue Source Type: research