Nocturnal Hypertension Unveiled: Protect Your Health While You Sleep
Is your blood pressure working the night shift? Let’s decode the mysteries of nocturnal hypertension together – from its symptoms and causes, to diagnosis and effective management. Sleep peacefully with our handy guide! Quick Summary Nocturnal Hypertension refers to high blood pressure that occurs at night, usually when blood pressure should naturally dip due to the circadian rhythm. Risk factors for nocturnal hypertension include conditions such as sleep apnea, diabetes, kidney disease, and lifestyle factors like high salt intake and lack of adequate sleep. Diagnosis and management of nocturna...
Source: The EMT Spot - June 3, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

Dangers And Risks Of High Blood Pressure
Conclusion Despite its silent nature, high blood pressure gradually damages organs over time. The interconnectedness of the circulatory system means that all organs reachable by blood are at risk. Hypertension can lead to critical complications such as heart enlargement, coronary artery disease, stroke, cognitive decline, erectile dysfunction, kidney disease, proteinuria, vision problems, and vascular damage. The importance of proactive measures to manage and prevent these adverse effects is emphasized. Regular blood pressure monitoring, adopting a healthy lifestyle, and working with healthcare professionals ar...
Source: The EMT Spot - June 1, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

27 Dangers And Risks Of High Blood Pressure
Conclusion Despite its silent nature, high blood pressure gradually damages organs over time. The interconnectedness of the circulatory system means that all organs reachable by blood are at risk. Hypertension can lead to critical complications such as heart enlargement, coronary artery disease, stroke, cognitive decline, erectile dysfunction, kidney disease, proteinuria, vision problems, and vascular damage. The importance of proactive measures to manage and prevent these adverse effects is emphasized. Regular blood pressure monitoring, adopting a healthy lifestyle, and working with healthcare professionals ar...
Source: The EMT Spot - June 1, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

LEAP2 / Ghrelin Ratio as a Marker of Cognitive Decline
Ghrelin signaling is a part of being hungry. The cell signaling involved in the state hunger appears to be an important part of the process by which fasting and calorie restriction improve cell metabolism, tissue function, and long-term health. Researchers here investigate LEAP2, an inhibitor of ghrelin signaling, finding that more of it correlates with worse cognitive function with age. Given what we know of the way in which hunger affects health, LEAP2 may also prove to be yet another target for future therapies that can mimic some of the effects of calorie restriction. Elderly individuals frequently report cogn...
Source: Fight Aging! - June 1, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, May 29th 2023
In this study, we used a Drosophila model to understand the role of the dec2P384R mutation on animal health and elucidate the mechanisms driving these physiological changes. We found that the expression of the mammalian dec2P384R transgene in fly sleep neurons was sufficient to mimic the short sleep phenotype observed in mammals. Remarkably, dec2P384Rmutants lived significantly longer with improved health despite sleeping less. In particular, dec2P384R mutants were more stress resistant and displayed improved mitochondrial fitness in flight muscles. Differential gene expression analyses went on to reveal several altered tr...
Source: Fight Aging! - May 28, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Can You Take Birth Control Pills With Hypertension?
Navigating birth control options when living with hypertension can be challenging. This comprehensive overview explores the complex relationship between birth control pills and high blood pressure, addressing scientific research, potential risks, and viable alternatives. It underscores the importance of personalized medical advice in making safe and informed contraceptive choices. Quick Summary Combined oral contraceptives can potentially raise blood pressure levels, making them a risk for women already diagnosed with hypertension. Alternatives such as progestin-only pills, IUDs, barrier methods, and contrace...
Source: The EMT Spot - May 25, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

Using Robots and Artificial Intelligence to Search for New Medicines
Courtesy of Dr. Adam Gormley. Adam Gormley, Ph.D., describes himself as a creative and adventurous person—albeit, not creative in the traditional sense. “Science allows me to be creative; to me, it’s a form of art. I love being outdoors, going on sailing trips, and spending time adventuring with my family. Research is the same—it’s an adventure. My creative and adventurous sides have combined into a real love for science,” he says. Dr. Gormley currently channels his passion for science into his position as an assistant professor of biomedical engineering at Rutgers University in Piscataway, New Jersey. Lea...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - May 24, 2023 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Cells Tools and Techniques Bioinformatics Computational Biology Medicines Profiles Source Type: blogs

Reviewing mTOR Inhibition as a Pharmacological Strategy to Modestly Slow Aging
It is arguably the case that we should look at small molecule mTOR inhibitors, such as rapamycin and its descendant rapalog compounds, as the most effective of the calorie restriction mimetic approaches developed to date. The practice of calorie restriction, eating as much as 40% fewer calories while still obtaining optimal levels of micronutrients, produces sweeping changes to metabolism. Some of these, such as increased autophagy and other forms of cellular housekeeping, appear to be beneficial to long-term health. Keeping cells more free of damage leads to a slowing of aging. In mice, that slowing of aging can le...
Source: Fight Aging! - May 23, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Paper Strip Tests for Hypothyroidism
Student researchers at Rice University have developed a paper strip test for hypothyroidism, similar to those that are commonly used for COVID-19 testing. Babies with congenital hypothyroidism require prompt diagnosis and treatment, but in many parts of the world a lack of healthcare resources can mean that the condition can go undiagnosed for long periods, affecting a child’s development. This paper-based device may be well suited for large screening programs in such countries, as it is inexpensive and easy to use, requiring just a small drop of blood. The device consists of a wicking pad that is impregnated with antibo...
Source: Medgadget - May 19, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Diagnostics Medicine Pediatrics riceuniversity Source Type: blogs

Steroids And The Heart: A Revealing Study On Long-Term Risks
Conclusion: A Heartfelt Wake-Up Call These pioneering studies serve as a stark reminder that every choice has consequences – and when it comes to anabolic steroids, those consequences can be heart-wrenching. The results underscore the urgency of prioritizing health over fleeting performance gains. As we step forward, awaiting more insights from larger studies, remember – your health is an invaluable asset, one that deserves more than temporary boosts. Making conscious, informed choices today can shield your heart from undue harm tomorrow. References American Heart Association: Steroids, Other A...
Source: The EMT Spot - May 15, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs

Is FDA-approved Veozah a game-changer in menopause hot flash treatment?
The medical world is buzzing following the FDA’s green light for Veozah. This is a one-of-a-kind, non-hormonal drug designed to tackle hot flashes in menopausal women. It brings fresh hope to countless women in the U.S. who’ve been grappling with these troublesome symptoms. Around 80 percent of menopausal women suffer from hot flashes, which bring Read more… Is FDA-approved Veozah a game-changer in menopause hot flash treatment? originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - May 12, 2023 Category: General Medicine Authors: Tags: KevinMD Medications OB/GYN Source Type: blogs

Making the Mundane Magnificent: A Fresh Approach to Everyday Tasks
We all have those mundane tasks that we can’t seem to shake off our to-do lists – the ones that make us sigh just thinking about them. But let’s challenge this mindset: Is the task boring or are we approaching it with a boring mindset? What if the task isn’t inherently dreadful, but we’re simply being uninteresting in how we approach it? What would happen if we were to bring a fun, engaging, and playful mindset to these tasks? Consider the simple act of doing household chores. They can often feel tedious, right? But let’s reframe. Instead of approaching them with a sense of dread, I often pai...
Source: Steve Pavlina's Personal Development Blog - May 11, 2023 Category: Psychiatry & Psychology Authors: Steve Pavlina Tags: Creating Reality Emotions Productivity Source Type: blogs

Capsule Delivers Electrical Current to Stomach for Appetite
This study helps establish electrical stimulation by ingestible electroceuticals as a mode of triggering hormone release via the GI tract,” said Giovanni Traverso, a researcher involved in the study. “We show one example of how we’re able to engage with the stomach mucosa and release hormones, and we anticipate that this could be used in other sites in the GI tract that we haven’t explored here.” The MIT team designed the capsule for maximum contact with the stomach wall. Fluids in the stomach could interfere with this, so the capsule contains small grooves with a hydrophilic coating that d...
Source: Medgadget - May 10, 2023 Category: Medical Devices Authors: Conn Hastings Tags: GI Oncology cachexia mit Source Type: blogs

The Power of Connection: Why Building Relationships Is the Key to Personal and Professional Success
Establishing deep meaningful genuine relationships with others is a vital aspect of personal and professional success. Numerous studies have found that social connections are essential for our overall well-being, both physical and mental. Despite this, people often tend to overlook its importance in their lives. There’s plenty of reasons behind it. Firstly, the hectic nature of modern-day life may involve long working hours and various other responsibilities. Consequently, people fail to allocate adequate time to nurture their relationships with others.  Secondly, we’ve got spoiled by the simplicity of conne...
Source: PickTheBrain | Motivation and Self Improvement - May 8, 2023 Category: Consumer Health News Authors: Ilya Rouss Tags: career communication confidence creativity featured internet culture philosophy productivity tips self-improvement success connection Source Type: blogs

Fight Aging! Newsletter, May 8th 2023
In conclusion, NAT mitigated age-associated cerebral injury in mice through gut-brain axis. The findings provide novel evidence for the effect of NAT on anti-aging, and highlight the potential application of NAT as an effective intervention against age-related diseases. Retinal Cell Reprogramming Restores Vision in Non-Human Primate Study https://www.fightaging.org/archives/2023/05/retinal-cell-reprogramming-restores-vision-in-non-human-primate-study/ Early applications of in vivo cellular reprogramming to medicine are cautiously focused on retinal regeneration. The eye is as close to an isolated system...
Source: Fight Aging! - May 7, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs