Transgender health risks in hormone therapy
Reportedly, there are at least 1.6 million people who identify as transgendered in the United States. Approximately one-third of them are transgendered male-to-females, referred to as “T-girls.” These individuals have a strong desire to be passable without undergoing surgery, relying instead on hormone therapy. However, hormonal therapy is not without risks. Testosterone, used in protocols Read more… Transgender health risks in hormone therapy originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - July 27, 2023 Category: General Medicine Authors: Tags: Conditions Oncology/Hematology Source Type: blogs

Vasodilators For High Blood Pressure: Types, Side Effects, Drug Interactions
Conclusion In summary, vasodilators play a pivotal role in managing cardiovascular conditions, including hypertension, which is rapidly becoming a global health concern. By expanding the body’s blood vessels, these unique medications can improve blood flow and decrease the pressure exerted by the heart, thereby providing relief to numerous patients worldwide. Their applications are diverse, extending beyond hypertension to conditions like angina, heart failure, and even erectile dysfunction. However, these medications should be taken carefully and always under the supervision of a doctor due to the potent...
Source: The EMT Spot - July 27, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

Why Am I So Tired?
Circadian rhythms control the timing of many daily changes in your body. Credit: iStock. If you struggle to wake up in time for school or work or feel drowsy during a trip abroad, your circadian rhythms may be out of sync with your environment. Circadian rhythms are your internal timekeepers, and almost all organisms, from bacteria to plants and animals, have them. You can’t see them, but you can feel their effects—they control when you get sleepy, when you wake up in the morning, and when you feel hungry. Among other signals, the brain uses sunlight to keep time. Changing Circadian Rhythms Exposure to ligh...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - July 26, 2023 Category: Research Authors: Chrissa Chverchko Tags: Chemistry, Biochemistry and Pharmacology Biological Clocks Common questions Source Type: blogs

Beta-Blockers For High Blood Pressure: Types, Side Effects, Drug Interactions
Conclusion In conclusion, beta-blockers serve as an indispensable tool in the realm of modern medical treatment, particularly in managing a broad range of cardiovascular conditions. Their unique mechanism of action, which includes decreasing heart rate and blood pressure, confers a significant cardio-protective effect. This, combined with their versatility and the extensive clinical experience with their use, has cemented beta-blockers as a first-line treatment for various conditions, from hypertension and heart failure to anxiety and migraines. Although beta-blockers present unique benefits, it’s crucial...
Source: The EMT Spot - July 24, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

Zilebesiran: A Promising Leap Forward In Hypertension Management
Conclusion As we draw the curtain on this insightful dive into Zilebesiran, a couple of takeaways stand out. Zilebesiran, the promising twice-yearly shot, is opening new frontiers in hypertension management. With its ability to suppress angiotensin production, it offers a fresh approach that could alleviate the burden of daily pill regimens. But the shot is still in its developmental phase, and further research is crucial to fully understand its capabilities and limitations. Still, it’s important to remember that medications are only a part of the solution. The enduring message from health professionals is ...
Source: The EMT Spot - July 24, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs

How Alcohol Affects Blood Pressure: A Detailed Insight
Conclusion In this guide, we’ve explored the complex relationship between alcohol and blood pressure. We’ve seen that alcohol, whether consumed moderately, heavily, or in a binge pattern, can impact blood pressure. We also delved into the biological mechanisms at play, the role of various drinking patterns, and the sobering revelations of recent research. While the pleasure of a drink might be fleeting, its effects on our body, particularly on our blood pressure, can be long-lasting. The key takeaway? Moderation. Even a small reduction in alcohol intake can have significant health benefits, partic...
Source: The EMT Spot - July 18, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

Can minors truly consent to reversible puberty blockers in gender-affirming health care?
Gender-affirming health care (GAH) is a rapidly developing sector within the medical profession that can include indirect therapies such as counseling, direct therapies such as hormone treatments, puberty blockers, or gender-affirming surgeries. A main ethical concern with GAH resides in its use on adolescents, and this paper will primarily explore the use of puberty blockers, Read more… Can minors truly consent to reversible puberty blockers in gender-affirming health care? originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - July 17, 2023 Category: General Medicine Authors: Tags: Conditions Pediatrics Source Type: blogs

Fight Aging! Newsletter, July 17th 2023
In conclusion, the longevity-associated genotype of FLT1 may confer increased lifespan by protecting against mortality risk posed by hypertension. We suggest that FLT1 expression in individuals with longevity genotype boosts vascular endothelial resilience mechanisms to counteract hypertension-related stress in vital organs and tissues. Resistance Exercise Slows the Onset of Pathology in a Mouse Model of Alzheimer's Disease https://www.fightaging.org/archives/2023/07/resistance-exercise-slows-the-onset-of-pathology-in-a-mouse-model-of-alzheimers-disease/ With the caveat that mouse models of Alzheimer'...
Source: Fight Aging! - July 16, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Wearable Takes Blood-Free Stress Hormone Samples
Researchers at the University of Birmingham in the UK have developed a wearable that can assist in keeping track of stress hormone levels in the body over time. Disregulated stress hormones can play a role in various disease states, from heart disease to depression. However, until now, researchers had to perform blood draws to measure stress hormone levels, meaning that they could obtain just one snapshot in time of hormone levels or repeated blood draws over time, neither of which are ideal. This latest technology, called U-RHYTHM, acts as a wearable sampling device, and can obtain stress hormone samples from beneath the ...
Source: Medgadget - July 14, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Diagnostics Medicine stress hormone unibirmingham Source Type: blogs

Recombinant Klotho Treatment Improves Cognitive Function in Old Rhesus Macaques
Klotho is one of the few genuinely longevity-associated genes, in that greater than normal expression increases life span in mice, while lower than normal expression shortens life span in mice. In humans, greater levels of circulating soluble klotho correlate with greater longevity. Klotho is thought to operate in the kidneys, in some way that is protective against the mechanisms of age-related decline, but there is a great deal of evidence for greater circulating klotho to improve cognitive function. At the same time, it seems unclear as to whether klotho is actually doing anything in the brain; it may be that the benefit...
Source: Fight Aging! - July 12, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

5 Signs You Are Sabotaging Your Inner Peace
Image by Anthony Tran on Unsplash According to the United Nations (UN), nearly one billion people worldwide deal with mental health issues. Experts have tried to pinpoint the reasons, with the Center for Disease Control and Prevention (CDC) blaming a combination of childhood trauma, medical factors, biological brain imbalances, alcohol or drug use, and emotions.  In layman's terms, it could all boil down to a lack of inner peace. The Bible defines inner peace as peace achieved in communion with God through Jesus Christ. To Buddhists, it is "an awakening to an ultimate inseparability between our own well-being...
Source: PickTheBrain | Motivation and Self Improvement - July 12, 2023 Category: Consumer Health News Authors: Erin Falconer Tags: featured happiness health and fitness meditation philosophy psychology self-improvement inner peace Source Type: blogs

Angiotensin II Receptor Blockers (ARBs) For High Blood Pressure: Types, Side Effects, Drug Interactions
Conclusion Cardiovascular disease (CVD) has become a leading cause of death globally, necessitating the adoption of preventive measures, early detection, and effective management strategies. Hypertension, a significant risk factor for CVD, requires active management to mitigate associated risks. Angiotensin II Receptor Blockers (ARBs) have emerged as a favored choice among healthcare professionals due to their effectiveness and unique benefits. ARBs offer several advantages compared to other blood pressure medications. They effectively control blood pressure, protect vital organs such as the heart and kidneys, ...
Source: The EMT Spot - July 11, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

ACE Inhibitors For High Blood Pressure: Types, Side Effects, Drug Interactions
Conclusion In conclusion, the rising utilization of blood pressure medications reflects a growing awareness of the importance of managing hypertension for overall health. ACE inhibitors, among other drug classes, are widely used due to their effectiveness in lowering blood pressure and providing additional benefits for heart and kidney health. It’s essential to consult your doctor before starting or adjusting ACE inhibitor treatment to ensure personalized care and monitor for potential side effects or drug interactions. Taking ACE inhibitors as prescribed, following consistent dosing schedules, and attend...
Source: The EMT Spot - July 9, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

Fight Aging! Newsletter, July 10th 2023
In conclusion, the examination of the GBA can aid in understanding the etiology and development of NDs, which may benefit the improvement of clinical treatments for these disorders and ND interventions. This review indicates existing knowledge about the involvement of microbiota present in the gut in NDs and potential treatment options. The Aging of the Enteric Nervous System https://www.fightaging.org/archives/2023/07/the-aging-of-the-enteric-nervous-system/ The enteric nervous system is the nervous system of the intestines, and likely an important part of the relationship between the gut microbiome ...
Source: Fight Aging! - July 9, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Bill Would Ban Care for Transgender Veterans; the Scientific and Medical Consensus Tells Us That's a Mistake
The recently-released spending bill would prevent the Department of Veterans Affairs from beginning to offer gender confirmation surgery. It would also prevent providers from offering hormone therapy for gender-affirming care. These provisions do not align with the state of the science and medical consensus and would harm vulnerable veterans. (Source: The RAND Blog)
Source: The RAND Blog - July 5, 2023 Category: Health Management Authors: Kayla M. Williams Source Type: blogs