The Aging of the Enteric Nervous System
The enteric nervous system is the nervous system of the intestines, and likely an important part of the relationship between the gut microbiome and the brain. One of the more interesting parts of this review paper is the discussion regarding relationships between the gut microbiome and enteric nervous system. All too little is known in detail, even while it is possible to find reports of specific associations and points of communication between gut microbiome and nervous system. Given the attention to measuring and altering the balance of populations in the gut microbiome, one might hope that the advent of ways to sizeably...
Source: Fight Aging! - July 3, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, July 3rd 2023
In this study, cultured adipose-derived stem cells (ASCs) were derived from subcutaneous white adipose tissue isolated from mice fed a normal diet. We performed senescence-associated-β-galactosidase (SA-β-gal) staining, real-time PCR, and Western blot to evaluate the levels related to cellular senescence markers.
The mRNA expression levels of senescence markers were significantly increased in the later passages of ASCs. We show that light activation reduced the expression of senescent genes, and SA-β-Gal in all cells at passages. Moreover, the light-activated ASCs-derived exosomes decrease the expression of senes...
Source: Fight Aging! - July 2, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Reviewing the Role of TFEB Upregulation in Approaches Shown to Slow Aging
Most of the varied approaches shown to modestly slow the progression of aging appear to operate through a small number of common mechanisms, largely involving the cellular response to stress. Some of those mechanisms will turn out to be more influential than others, though little progress has been made towards assigning relative importance to the various layers of the exceedingly complex reactions to heat, cold, restriction of nutrients, and other forms of mild stress that can produce beneficial outcomes.
The most compelling evidence to date suggests that improved autophagy is one of the more relevant portions of th...
Source: Fight Aging! - June 28, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Like Don Quixote Chasing Windmills, I Aim to See Financial Remediation for Patients Still Suffering in a Predatory U.S Healthcare System
Sometimes, I feel (if you pardon the metaphor) a bit like Don Quixote chasing windmills with my efforts to see true financial remediation introduced in the predatory U.S. healthcare " system " (and I am glad to see that the term " predatory " is now being used by a growing number of medical doctors, which I think is great). I envision a type of financial remediation whereby patients will be able to get access to the care they need without having to face financial predators trying to pick their pockets with illegal discount bribes standing in the way of their getting access to things they need like insulin, CGM senors ...
Source: Scott's Web Log - June 25, 2023 Category: Endocrinology Tags: 2023 CGM Formulary Exclusion insulin PBM Source Type: blogs
Can You Drink Licorice With Hypertension?
Conclusion
It’s clear that licorice, with its potent compound glycyrrhizin, can potentially raise blood pressure. This makes it a food item to approach with caution for those living with hypertension. But, remember, not all “licorice” you see on shelves contains real licorice root or extract. Checking labels can help identify those sneaky substitutes.
Moderation and informed choices are your allies. While occasional licorice consumption might be fine for some, it’s always best to consult your healthcare provider to ensure you’re not jeopardizing your well-being.
Delicious alternatives...
Source: The EMT Spot - June 24, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs
8 Risk Factors Of Low Blood Pressure
Conclusion
In a nutshell, understanding the risk factors associated with low blood pressure is essential for maintaining good health.
Individuals with certain risk factors, such as age, medication usage, underlying medical conditions, dehydration, prolonged bed rest, nutritional deficiencies, pregnancy, and inherited factors, should be particularly aware of the potential for low blood pressure.
Regular monitoring of blood pressure, communication with healthcare providers, and appropriate management strategies are important for individuals with these risk factors to ensure their well-being.
Furthermore, diet pla...
Source: The EMT Spot - June 23, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs
Fight Aging! Newsletter, June 19th 2023
In conclusion, among Swedish middle-aged subjects, nearly two-thirds showed complete fatty degeneration of thymus on CT.
Age-Related Dysfunction of Water Homeostasis
https://www.fightaging.org/archives/2023/06/age-related-dysfunction-of-water-homeostasis/
Dehydration can be an issue in older people. As in every complex system in the body, the mechanisms by which hydration is regulated become dysfunctional with advancing age. Researchers here look at the brain region responsible for regulating some of the response to dehydration, cataloging altered gene expression in search of the more important mechan...
Source: Fight Aging! - June 18, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Juicy Discovery: Can Japanese Plum Juice Beat Hypertension?
Conclusion: The Future Of Bainiku-Ekisu
The next phase of Dr. Eguchi’s research intends to pinpoint the specific compounds in bainiku-ekisu responsible for its protective effects.
He suggested that there might be two or three compounds acting in concert, resulting in additive or synergistic effects potentially lost in a pharmaceutical preparation.
This research, sponsored by the National Institutes of Health and a research gift fund from Kobayashi Pharmaceutical Japan, might be an important step forward in managing hypertension and preventing cardiovascular diseases.
Time will reveal whether the humble ...
Source: The EMT Spot - June 14, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs
7 Diagnosis And Tests For Low Blood Pressure: A Comprehensive Guide
Conclusion
Accurate assessment and recognition of low blood pressure are crucial for effective management.
Diagnostic techniques, including medical history assessment, physical examination, ECG, blood tests, Holter monitor, tilt table test, stress test, and imaging tests, help identify underlying causes, assess severity, and rule out complications.
Smart blood pressure monitors connected to mobile devices have revolutionized diagnosis and monitoring. These devices provide instant, accurate readings for real-time tracking and analysis.
This involves increasing salt intake, staying hydrated, exercising regularly,...
Source: The EMT Spot - June 13, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs
“We Are Electric” by Sally Adee: Medgadget Interviews the Author
The human body has a deep connection with electricity. The transmission of electrical impulses is responsible for the movement of our limbs, the functioning of our organs, and the formation and recall of memories. The signatures of the various electrical signals emanating from our body can be telltale signs of our health, and a jolt of electricity can literally bring us back from the brink of death.
But while these things have long been known about the electricity constantly coursing through our bodies, what has more recently been discovered is the role that “bioelectricity” plays in the formation of our bod...
Source: Medgadget - June 12, 2023 Category: Medical Devices Authors: Scott Jung Tags: Education etc. Exclusive Source Type: blogs
5 Low Blood Pressure Treatment Methods: From Lifestyle Changes To Medication
Conclusion
Treating low blood pressure is essential for maintaining overall health and well-being. While low blood pressure is often considered a healthy sign of a well-functioning heart, it can cause troublesome symptoms and potentially lead to complications.
Medications, such as Fludrocortisone, Midodrine, and Alpha-1 agonists, are commonly prescribed to stabilize blood pressure and address the underlying causes.
Lifestyle changes, such as augmenting salt consumption, maintaining adequate hydration, and utilizing compression stockings, can also positively impact the management of low blood pressure.
Additiona...
Source: The EMT Spot - June 12, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs
Age-Related Dysfunction of Water Homeostasis
Dehydration can be an issue in older people. As in every complex system in the body, the mechanisms by which hydration is regulated become dysfunctional with advancing age. Researchers here look at the brain region responsible for regulating some of the response to dehydration, cataloging altered gene expression in search of the more important mechanisms involved in the vulnerability of old people to harmful levels of dehydration.
Ageing is accompanied by an increased prevalence of disorders of body salt and water composition. As revealed by the UK Dehydration Recognition In Our Elders (DRIE), 20% of residents in ...
Source: Fight Aging! - June 12, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Oral Estrogen Linked To High Blood Pressure Risk: An In-depth Study Analysis
Conclusion
As a whole, this study indicates a strong correlation between the method of estrogen administration and the risk of hypertension.
Oral estrogen seems to carry a higher risk compared to transdermal patches and vaginal creams.
The duration and dosage of estrogen consumption are also significant factors.
Remember, regular self-monitoring is critical, and for that, we provide valuable guides on our website for things like ‘how to lower blood pressure’ and ‘checking blood pressure at home’.
Stay informed, stay healthy!
Read also: E-Tattoos: The Cool & Easy Way To Track...
Source: The EMT Spot - June 8, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs
5 Causes Of Low Blood Pressure You Might Not Know About
Conclusion
Low blood pressure, although often associated with a healthy cardiovascular system, can also indicate underlying health issues.
It is crucial to recognize that low blood pressure should not be disregarded, particularly when accompanied by symptoms or fluctuations.
This article explored the causes of low blood pressure, including cardiovascular conditions, hormonal imbalances, and neurological disorders.
Smart heart care, including the use of blood pressure monitors and natural supplements, was emphasized as a proactive approach to maintaining a healthy life.
Understanding the causes and implementi...
Source: The EMT Spot - June 8, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs
Fight Aging! Newsletter, June 5th 2023
In conclusion, higher BMR might reduce lifespan. The underlying pathways linking to major causes of death and relevant interventions warrant further investigation.
Betting Against Progress Turns Out Poorly, But Can Work in the Short Term in a Slow Field
https://www.fightaging.org/archives/2023/06/betting-against-progress-turns-out-poorly-but-can-work-in-the-short-term-in-a-slow-field/
Setting oneself up as a spokesperson for "we will not achieve this goal", as the fellow noted here is choosing to do, is a bet against technological progress. A glance at any few decade period in the past two hundred yea...
Source: Fight Aging! - June 4, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
