Fight Aging! Newsletter, June 5th 2023

In conclusion, higher BMR might reduce lifespan. The underlying pathways linking to major causes of death and relevant interventions warrant further investigation. Betting Against Progress Turns Out Poorly, But Can Work in the Short Term in a Slow Field https://www.fightaging.org/archives/2023/06/betting-against-progress-turns-out-poorly-but-can-work-in-the-short-term-in-a-slow-field/ Setting oneself up as a spokesperson for "we will not achieve this goal", as the fellow noted here is choosing to do, is a bet against technological progress. A glance at any few decade period in the past two hundred years suggests that such a bet will almost certainly fail in time, sometimes quite rapidly. In highly regulated fields that move as slowly as is the case for medicine, however, one can profitably continue to be a skeptic for quite some time. While progress is rapid and impressive in the lab and in animal studies, a skeptic can continue to shrug and point to the lack of human therapies. This is the result of an excessive burden of regulatory cost: rapid progress in the lab, in a revolutionary era of increasing capacity, improving tools, and falling costs, runs up against a wall of regulatory delay and vast expense. It takes twenty years to move from early research to mode of therapy to clinical approval, and few programs make it all the way, abandoned in the face of a cost that no-one is willing to pay. All skeptics setting themselves up in general opposi...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs