You need to ask these questions to teens starting hormone therapy [PODCAST]
Subscribe to The Podcast by KevinMD. Catch up on old episodes! “A good history and physical, including screening, can prevent consequences that burden a patient’s daily life and increase health care costs. Assessing cardiovascular risk is a key part of the evaluation. Transgender individuals may have a compounded risk. Awareness and education for both the Read more… You need to ask these questions to teens starting hormone therapy [PODCAST] originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - December 14, 2022 Category: General Medicine Authors: Tags: Podcast Endocrinology Pediatrics Source Type: blogs

5 Simple Habits and Routines to Keep You Away from Depression and Stress
One of the major problems facing today’s generation is depression. Excessive workload, changing lifestyle, loneliness, and financial pressure all lead to stress which results in depression. You feel unhappy, non-productive and withdrawn when you are depressed.  Many experts believe that establishing routines filled with healthy habits is a great way to move more efficiently through your day while expending less mental energy and even willpower in the process. Following simple routines like exercising, eating the right food, taking energy supplements, meditating, and getting sufficient sleep can help to manage str...
Source: PickTheBrain | Motivation and Self Improvement - December 13, 2022 Category: Consumer Health News Authors: Erin Falconer Tags: featured happiness health and fitness self-improvement Source Type: blogs

Fight Aging! Newsletter, December 5th 2022
In conclusion, the PAAIs examined (i.e. mTOR loss of function, Ghrhr loss of function, intermittent fasting-based version of dietary restriction) often influenced age-sensitive traits in a direct way and not by slowing age-dependent change. Previous studies often failed to include young animals subjected to PAAI to account for age-independent PAAI effects. However, any study not accounting for such age-independent intervention effects will be prone to overestimate the extent to which an intervention delays the effects of aging on the phenotypes studied. This can result in a considerable bias of our view on how modifiable a...
Source: Fight Aging! - December 4, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Calorie Restriction as a Treatment to Slow Parkinson's Disease
Calorie restriction is known to suppress inflammation to some degree, alongside many other benefits to health that result from the reaction of cells and biological systems to a reduced calorie intake. Since chronic inflammation in brain tissue is implicated in the onset and development of neurodegenerative conditions, this makes calorie restriction a topic of interest in this part of the field. With a few exceptions, that interest largely manifests as research aimed at reproducing some of the metabolic alterations of calorie restriction with small molecule drugs, however, rather than more more rigorously testing calorie re...
Source: Fight Aging! - December 2, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Arguing for Well Explored Approaches to Slow Aging to Not In Fact Slow Aging
In conclusion, the PAAIs examined (i.e. mTOR loss of function, Ghrhr loss of function, intermittent fasting-based version of dietary restriction) often influenced age-sensitive traits in a direct way and not by slowing age-dependent change. Previous studies often failed to include young animals subjected to PAAI to account for age-independent PAAI effects. However, any study not accounting for such age-independent intervention effects will be prone to overestimate the extent to which an intervention delays the effects of aging on the phenotypes studied. This can result in a considerable bias of our view on how modifiable a...
Source: Fight Aging! - November 28, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

On Preventive Care Coverage, Let the People Choose
Michael F. CannonA federal judge in Texas is weighing whether to free consumers nationwide from an unconstitutional ObamaCare requirement that they purchase coverage they do not want, theWall Street Journalreports. He should do so.In September, Judge Reed O ’Connor of the U.S. District Court for the Northern District of Texas ruled that ObamaCare violates the Constitution by giving the U.S. Preventive Services Task Force (USPSTF) the power to dictate particular types of coverage consumers must purchase. O’Connor ruled that provision unconstitutiona l because USPSTF members would have to receive Senate confirmation to w...
Source: Cato-at-liberty - November 28, 2022 Category: American Health Authors: Michael F. Cannon Source Type: blogs

Fight Aging! Newsletter, November 28th 2022
This study explored whether determining the gain or loss of specific taxa represent a more precise metric of healthy/unhealthy aging than summary microbiome statistics, such as diversity and uniqueness. We analyzed microbiome diversity and four measures of microbiome uniqueness in 21,000 gut microbiomes for their relationship with aging and health. We show that diversity and uniqueness measures are not synonymous; uniqueness is not a uniformly desirable feature of the aging microbiome, nor is it an accurate biomarker of healthy aging. Different measures of uniqueness show different associations with diversity and with mark...
Source: Fight Aging! - November 27, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Gene Pathway Analysis In Action – 3 × 4 DNA Test Review
In the past couple of years, I have taken at least 10 genetic tests, including this latest DNA test from 3×4 Genetics. This may seem excessive, but I have my reasons. I graduated from medical school as a genetic specialist and completed my PhD as a clinical genomics researcher, and although I turned to medical futurism, my original field never ceases to fascinate me. I’m very curious about how these tests advance and hope I might be able to provide insights for patients worldwide about what they can expect to learn from such tests and what those tests can really deliver. Thus, I didn’t hesitate for a second to ...
Source: The Medical Futurist - November 24, 2022 Category: Information Technology Authors: Andrea Koncz Tags: Genomics Personalized Medicine dna testing genetic test Genetic testing review dna test review 3x4 Genetics pathway analysis Source Type: blogs

IGF1 Gene Therapy as a Neuroprotective Treatment, Slowing Female Reproductive Aging
Researchers here describe an interesting approach to slowing aspects of neurodegeneration that contribute to, among other things, female reproductive aging. That is the focus of this paper, but numerous other aspects of the aging brain are also involved. IGF1 is well studied in the context of aging, and manipulation of the signaling pathways linking insulin, IGF1, and growth hormone has been shown to extend life span in a number of species. Where we can make direct comparisons between mice and humans, such as between growth hormone receptor knockout mice and humans with Laron syndrome, the effects are nowhere near as large...
Source: Fight Aging! - November 23, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Where Does Diabetes Technology Stand In 2022?
Diabetes management went through a radical transformation in the last years due to technology: the diabetes patient community found a strong voice online, continuous glucose monitors are taking the place of finger pricks, digital patches and insulin pumps make the dosage of insulin more predictable, and connected devices promise the era of artificial pancreas real soon. We looked around where diabetes technology stands today and what could we expect in the next 5-10 years. The diabetes community and digital health tech companies pushing for change Diabetes continues to affect the lives of millions around the globe. A...
Source: The Medical Futurist - November 22, 2022 Category: Information Technology Authors: berci.mesko Tags: Future of Medicine community diabetes digital digital health patient technology artificial pancreas blood diabetes management insulin diabetic health management blood sugar Source Type: blogs

Anemia in cardiac failure : Needs little more attention
HF is the inability (or reduced ability) to supply oxygen and other nutrients to fulfill the body’s demands. In the process, the heart either fights or flights, and results in symptoms due to hemodynamic alterations, or adversities of neuro-hormonal activation. Now, what is Anemia? Anemia is a condition with reduced or dysfunctional RBCs. that directly interferes with oxygen delivery to tissues. It is not at all a coincidence, the core functions of the heart and blood are strikingly similar and intertwined. While the heart is the powerhouse of the circulatory system, without good-quality blood, the greatness of th...
Source: Dr.S.Venkatesan MD - November 19, 2022 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized anemia in cardiac failure Source Type: blogs

Fight Aging! Newsletter, November 14th 2022
In this study, we show that TXNIP is vital for the cell fate choice when cells are challenged by various stress signals. Furthermore, prolonged IGF1 treatment leads to the establishment of a premature senescence phenotype characterized by a unique senescence network signature. Combined IGF1/TXNIP-induced premature senescence can be associated with a typical secretory inflammatory phenotype that is mediated by STAT3/IL-1A signaling. Finally, these mechanistic insights might help with the understanding of basic aspects of IGF1-related pathologies in the clinical setting. Investigating the Ability of Type 2 Diabetes...
Source: Fight Aging! - November 13, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

How To Lower Diastolic Blood Pressure Through Minor Lifestyle Changes?
ConclusionWhat Is Diastolic Blood Pressure? Diastolic blood pressure is the pressure in arteries during the resting phase of a heart. These range below 120 mmHg in a healthy human, whereas 120-129 is an elevated stage, and anything in between 130-139 mmHg or above is considered hypertension. Why Choose The Drug-Free Approach To Manage Blood Health? Managing blood health without using medicines is best for early-stage patients. There are a few reasons why one should choose a drug-free approach. First, drug-free approaches are often more effective in the long run. Second, these methods tend to have fewer side eff...
Source: The EMT Spot - November 11, 2022 Category: Emergency Medicine Authors: Michael Kutryk Tags: Guides Blood Pressure Source Type: blogs

Isolated Systolic Hypertension: Causes, Treatments, and More
ConclusionWhat Is Isolated Systolic Hypertension? If you have isolated systolic hypertension, your systolic blood pressure (the top number in the BP reading) is high, but your diastolic blood pressure (the bottom number) is normal. Stages of Isolated Systolic Hypertension Normal BP: 120/80 mmHg Elevated BP: 120-129/80 mmHg Hypertension Stage 1: 130-39/80-89 mmHg Hypertension Stage 2:  139 mmHg />89 mmHg Isolated systolic hypertension is more common in older adults. This condition is also more prevalent in men than women. Untreated isolated systolic hypertension can lead to serious health prob...
Source: The EMT Spot - November 11, 2022 Category: Emergency Medicine Authors: Michael Kutryk Tags: Guides Blood Pressure Source Type: blogs

What Is Epinephrine?
A quick inside tip on field instructors; we all have our favorite questions to ask new riders. Those questions that help us get a more firm understanding of where our students knowledge base rests. What kind of practical knowledge are they carrying out into the field? Some of them are fair questions. Some of them aren’t. That’s life. One of my favorite questions to ask that new rider early in the ride along is, “So what is epinephrine anyway?” (For the record, this is an extremely fair question.) I’ve found this to be a telling conversation because the scope of the question gives the student a l...
Source: The EMT Spot - November 10, 2022 Category: Emergency Medicine Authors: Steve Whitehead Tags: EMT Source Type: blogs