Molecules, Vol. 29, Pages 2028: Target Cell Extraction and Spectrum & ndash;Effect Relationship Coupled with BP Neural Network Classification for Screening Potential Bioactive Components in Ginseng Extract with a Protective Effect against Myocardial Damage
This study offers a reference for quality control in red ginseng and preparations containing red ginseng for the management of cardiovascular diseases. It also provides ideas for screening active ingredients of the same type of multi-pharmacologically active traditional Chinese medicines. (Source: Molecules)
Source: Molecules - April 28, 2024 Category: Chemistry Authors: Junyi Li Min Lin Zexin Xie Liwenyu Chen Jin Qi Boyang Yu Tags: Article Source Type: research

Noninvasive Ambulatory Electrocardiographic Markers from Patients with COVID-19 Pneumonia: A Report of Three Cases
Medicina (Kaunas). 2024 Apr 19;60(4):655. doi: 10.3390/medicina60040655.ABSTRACTCoronavirus disease 2019 (COVID-19) has affected medical practice. More than 7,000,000 patients died worldwide after being infected with COVID-19; however, no specific laboratory markers have yet been established to predict death related to this disease. In contrast, electrocardiographic changes due to COVID-19 include QT prolongation and ST-T changes; however, there have not been studies on the ambulatory electrocardiographic markers of COVID-19. We encountered three patients diagnosed as having COVID-19 who did not have a prior history of sig...
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Motohiro Kimata Kenichi Hashimoto Naomi Harada Yusuke Kawamura Yoshifumi Kimizuka Yuji Fujikura Mayuko Kaneko Nobuaki Kiriu Yasumasa Sekine Natsumi Iwabuchi Tetsuro Kiyozumi Akihiko Kawana Susumu Matsukuma Yuji Tanaka Source Type: research

Interoceptive signals from the heart and coronary circulation in health and disease
Auton Neurosci. 2024 Apr 24;253:103180. doi: 10.1016/j.autneu.2024.103180. Online ahead of print.ABSTRACTThis review considers interoceptive signalling from the heart and coronary circulation. Vagal and cardiac sympathetic afferent sensory nerve endings are distributed throughout the atria, ventricles (mainly left), and coronary artery. A small proportion of cardiac receptors attached to thick myelinated vagal afferents are tonically active during the cardiac cycle. Dependent upon location, these mechanoreceptors detect fluctuations in atrial volume and coronary arterial perfusion. Atrial volume and coronary arterial signa...
Source: Autonomic Neuroscience - April 27, 2024 Category: Neuroscience Authors: Jonathan P Moore Source Type: research

Noninvasive Ambulatory Electrocardiographic Markers from Patients with COVID-19 Pneumonia: A Report of Three Cases
Medicina (Kaunas). 2024 Apr 19;60(4):655. doi: 10.3390/medicina60040655.ABSTRACTCoronavirus disease 2019 (COVID-19) has affected medical practice. More than 7,000,000 patients died worldwide after being infected with COVID-19; however, no specific laboratory markers have yet been established to predict death related to this disease. In contrast, electrocardiographic changes due to COVID-19 include QT prolongation and ST-T changes; however, there have not been studies on the ambulatory electrocardiographic markers of COVID-19. We encountered three patients diagnosed as having COVID-19 who did not have a prior history of sig...
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Motohiro Kimata Kenichi Hashimoto Naomi Harada Yusuke Kawamura Yoshifumi Kimizuka Yuji Fujikura Mayuko Kaneko Nobuaki Kiriu Yasumasa Sekine Natsumi Iwabuchi Tetsuro Kiyozumi Akihiko Kawana Susumu Matsukuma Yuji Tanaka Source Type: research

Interoceptive signals from the heart and coronary circulation in health and disease
Auton Neurosci. 2024 Apr 24;253:103180. doi: 10.1016/j.autneu.2024.103180. Online ahead of print.ABSTRACTThis review considers interoceptive signalling from the heart and coronary circulation. Vagal and cardiac sympathetic afferent sensory nerve endings are distributed throughout the atria, ventricles (mainly left), and coronary artery. A small proportion of cardiac receptors attached to thick myelinated vagal afferents are tonically active during the cardiac cycle. Dependent upon location, these mechanoreceptors detect fluctuations in atrial volume and coronary arterial perfusion. Atrial volume and coronary arterial signa...
Source: Autonomic Neuroscience - April 27, 2024 Category: Neuroscience Authors: Jonathan P Moore Source Type: research

Noninvasive Ambulatory Electrocardiographic Markers from Patients with COVID-19 Pneumonia: A Report of Three Cases
Medicina (Kaunas). 2024 Apr 19;60(4):655. doi: 10.3390/medicina60040655.ABSTRACTCoronavirus disease 2019 (COVID-19) has affected medical practice. More than 7,000,000 patients died worldwide after being infected with COVID-19; however, no specific laboratory markers have yet been established to predict death related to this disease. In contrast, electrocardiographic changes due to COVID-19 include QT prolongation and ST-T changes; however, there have not been studies on the ambulatory electrocardiographic markers of COVID-19. We encountered three patients diagnosed as having COVID-19 who did not have a prior history of sig...
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Motohiro Kimata Kenichi Hashimoto Naomi Harada Yusuke Kawamura Yoshifumi Kimizuka Yuji Fujikura Mayuko Kaneko Nobuaki Kiriu Yasumasa Sekine Natsumi Iwabuchi Tetsuro Kiyozumi Akihiko Kawana Susumu Matsukuma Yuji Tanaka Source Type: research

Diabetic Cardiomyopathy-From Basics through Diagnosis to Treatment
Biomedicines. 2024 Mar 29;12(4):765. doi: 10.3390/biomedicines12040765.ABSTRACTDiabetic cardiomyopathy (DCM) is the development of myocardial dysfunction in patients with diabetes despite the absence of comorbidities such as hypertension, atherosclerosis or valvular defect. The cardiovascular complications of poorly controlled diabetes are very well illustrated by the U.K. Prospective Diabetes Study (UKPDS), which showed a clear association between increasing levels of glycated hemoglobin and the development of heart failure (HF). The incidence of HF in patients with diabetes is projected to increase significantly, which i...
Source: Atherosclerosis - April 27, 2024 Category: Cardiology Authors: Ewa Radzioch Bart łomiej Dąbek Marta Balcerczyk-Lis Weronika Fr ąk Piotr Fularski Ewelina M łynarska Jacek Rysz Beata Franczyk Source Type: research

Interoceptive signals from the heart and coronary circulation in health and disease
Auton Neurosci. 2024 Apr 24;253:103180. doi: 10.1016/j.autneu.2024.103180. Online ahead of print.ABSTRACTThis review considers interoceptive signalling from the heart and coronary circulation. Vagal and cardiac sympathetic afferent sensory nerve endings are distributed throughout the atria, ventricles (mainly left), and coronary artery. A small proportion of cardiac receptors attached to thick myelinated vagal afferents are tonically active during the cardiac cycle. Dependent upon location, these mechanoreceptors detect fluctuations in atrial volume and coronary arterial perfusion. Atrial volume and coronary arterial signa...
Source: Autonomic Neuroscience - April 27, 2024 Category: Neuroscience Authors: Jonathan P Moore Source Type: research

In Vitro Experimental Approach for Studying Human Pulmonary Artery Smooth Muscle Cells and Endothelial Cells Proliferation and Migration
Methods Mol Biol. 2024;2803:49-58. doi: 10.1007/978-1-0716-3846-0_4.ABSTRACTPulmonary arterial hypertension (PAH) is a severe vascular disease characterized by persistent precapillary pulmonary hypertension, leading to right heart failure and death. Despite intense research in the last decades, PAH remains an incurable disease with high morbidity and mortality. New directions and therapies to improve understanding and treatment of PAH are desperately needed. The pathological mechanisms leading to this fatal disorder remain mostly undetermined, although structural remodeling of the pulmonary vessels is known to be an early ...
Source: Mol Biol Cell - April 27, 2024 Category: Molecular Biology Authors: Seun Imani Roslyn Wallace Yassine Sassi Source Type: research

Noninvasive Ambulatory Electrocardiographic Markers from Patients with COVID-19 Pneumonia: A Report of Three Cases
Medicina (Kaunas). 2024 Apr 19;60(4):655. doi: 10.3390/medicina60040655.ABSTRACTCoronavirus disease 2019 (COVID-19) has affected medical practice. More than 7,000,000 patients died worldwide after being infected with COVID-19; however, no specific laboratory markers have yet been established to predict death related to this disease. In contrast, electrocardiographic changes due to COVID-19 include QT prolongation and ST-T changes; however, there have not been studies on the ambulatory electrocardiographic markers of COVID-19. We encountered three patients diagnosed as having COVID-19 who did not have a prior history of sig...
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Motohiro Kimata Kenichi Hashimoto Naomi Harada Yusuke Kawamura Yoshifumi Kimizuka Yuji Fujikura Mayuko Kaneko Nobuaki Kiriu Yasumasa Sekine Natsumi Iwabuchi Tetsuro Kiyozumi Akihiko Kawana Susumu Matsukuma Yuji Tanaka Source Type: research

Diabetic Cardiomyopathy-From Basics through Diagnosis to Treatment
Biomedicines. 2024 Mar 29;12(4):765. doi: 10.3390/biomedicines12040765.ABSTRACTDiabetic cardiomyopathy (DCM) is the development of myocardial dysfunction in patients with diabetes despite the absence of comorbidities such as hypertension, atherosclerosis or valvular defect. The cardiovascular complications of poorly controlled diabetes are very well illustrated by the U.K. Prospective Diabetes Study (UKPDS), which showed a clear association between increasing levels of glycated hemoglobin and the development of heart failure (HF). The incidence of HF in patients with diabetes is projected to increase significantly, which i...
Source: Atherosclerosis - April 27, 2024 Category: Cardiology Authors: Ewa Radzioch Bart łomiej Dąbek Marta Balcerczyk-Lis Weronika Fr ąk Piotr Fularski Ewelina M łynarska Jacek Rysz Beata Franczyk Source Type: research

Association between Statin Use and Chemotherapy-Induced Cardiotoxicity: A Meta-Analysis
Conclusion: Among patients of CIC, statin use has shown cardioprotective benefits by improving left ventricular function and reducing the risk of heart failure.PMID:38674227 | DOI:10.3390/medicina60040580 (Source: Cancer Control)
Source: Cancer Control - April 27, 2024 Category: Cancer & Oncology Authors: Vikash Jaiswal Song Peng Ang Novonil Deb Muhammad Hanif Nitya Batra Sai Gautham Kanagala Nikhil Vojjala Kripa Rajak Poulami Roy Medha Sharath Madeeha Subhan Waleed Zarghoona Wajid Jishanth Mattumpuram Source Type: research

Depression, Cardiovascular Disease, and Mortality
I read the paper by Krittanawong et al1 with great interest. The authors conducted a meta-analysis on the relationship between depression and the incidence of cardiovascular disease and cardiovascular disease outcomes. Pooled hazard ratios (HR) (95% confidence interval [CI]) of depression for incident stroke, myocardial infarction, congestive heart failure, and any cardiovascular diseases were 1.13 (1.00-1.28), 1.28 (1.14-1.45), 1.04 (1.00-1.09), and 1.16 (1.04-1.30), respectively. Regarding mortality risk, pooled HRs (95% CI) of depression for all-cause, cardiovascular disease, and congestive heart failure causes were 1.4...
Source: The American Journal of Medicine - April 27, 2024 Category: General Medicine Authors: Tomoyuki Kawada Tags: Letter Source Type: research

Serum brain natriuretic peptide levels may be a useful marker for early diagnosis of cardiomyopathy secondary to neuroblastoma: A case report
A 5-month-old boy with neuroblastoma showed dilated cardiomyopathy. Key Clinical MessageCardiomyopathy is a rare but serious complication associated with neuroblastoma. The brain natriuretic peptide level led to a diagnosis of secondary dilated cardiomyopathy before the worsening of heart failure symptoms. (Source: Clinical Case Reports)
Source: Clinical Case Reports - April 27, 2024 Category: General Medicine Authors: Natsumi Fujiyama, Osamu Matsuo, Takahiro Yamashita, Kensaku Kohrogi, Fumiya Miyamura, Tadashi Anan, Kimitoshi Nakamura Tags: CASE REPORT Source Type: research

Ketone body levels and its associations with cardiac markers following an acute myocardial infarction: a post hoc analysis of the EMMY trial
Sodium-glucose co-transporter 2 inhibitors (SGLT2i) have been suggested to exert cardioprotective effects in patients with heart failure, possibly by improving the metabolism of ketone bodies in the myocardium. (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 27, 2024 Category: Cardiology Authors: Faisal Aziz, Norbert J. Tripolt, Peter N. Pferschy, Hubert Scharnagl, Mahmoud Abdellatif, Abderrahim Oulhaj, Martin Benedikt, Ewald Kolesnik, Dirk von Lewinski and Harald Sourij Tags: Research Source Type: research