Sodium-Glucose Cotransporter-2 Inhibitors and the Risk for Dialysis and Cardiovascular Disease in Patients With Stage 5 Chronic Kidney Disease
CONCLUSION: This emulated target trial showed that SGLT2i use was associated with a lower risk for dialysis, cardiovascular events, DKA, and AKI than no SGLT2i use in patients with T2D and stage 5 CKD.PRIMARY FUNDING SOURCE: National Health Research Institutes, Taiwan.PMID:38684099 | DOI:10.7326/M23-1874 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 29, 2024 Category: Internal Medicine Authors: Fu-Shun Yen Chii-Min Hwu Jia-Sin Liu Yi-Ling Wu Keong Chong Chih-Cheng Hsu Source Type: research

Cellular Senescence as a Targetable Risk Factor for Cardiovascular Diseases: Therapeutic Implications: < em > JACC < /em > Family Series
JACC Basic Transl Sci. 2024 Apr 8;9(4):522-534. doi: 10.1016/j.jacbts.2023.12.003. eCollection 2024 Apr.ABSTRACTThe prevalence of cardiovascular diseases markedly rises with age. Cellular senescence, a hallmark of aging, is characterized by irreversible cell cycle arrest and the manifestation of a senescence-associated secretory phenotype, which has emerged as a significant contributor to aging, mortality, and a spectrum of chronic ailments. An increasing body of preclinical and clinical research has established connections between senescence, senescence-associated secretory phenotype, and age-related cardiac and vascular ...
Source: Atherosclerosis - April 29, 2024 Category: Cardiology Authors: Manish Kumar Pengyi Yan George A Kuchel Ming Xu Source Type: research

Exploring the Environmental Impact of Telemedicine: A Life Cycle Assessment
DISCUSSION: Given the frequent car travels, telemedicine emerges as a tool to improve environmental benefits and reduce time for patients and caregivers.PMID:38682509 | DOI:10.3233/SHTI240016 (Source: Studies in Health Technology and Informatics)
Source: Studies in Health Technology and Informatics - April 29, 2024 Category: Information Technology Authors: Anna Savoldelli Daniele Landi Caterina Rizzi Source Type: research

HerzMobil Tirol PreOp - A Multidisciplinary Telemonitoring Project for Heart Failure Patients Prior to Cardiac Surgery
CONCLUSION: Design of the first preoperative telemonitoring-assisted optimisation project for high-risk patients undergoing cardiac surgery.PMID:38682519 | DOI:10.3233/SHTI240026 (Source: Studies in Health Technology and Informatics)
Source: Studies in Health Technology and Informatics - April 29, 2024 Category: Information Technology Authors: Karin Hinterbuchner Elisabeth Kleinheinz Bettina Fetz Leo P ölzl Johannes Holfeld Bernhard Pfeifer Sabrina Neururer Christian Puelacher Can Gollmann-Tepekoeylue Susanne Krestan Andreas Huber Gerhard P ölzl Source Type: research

The Evolution of Telehealth in Heart Failure Management: The Role of Large Language Models and HerzMobil as a Potential Use Case
This study examines the integration of LLMs in heart failure management, with a focus on HerzMobil as a pioneering telehealth program. The technical underpinnings of LLMs, their current applications in the medical field, and their potential to enhance telehealth services, have been explored. The paper highlights the benefits of LLMs in patient interaction, clinical documentation, and decision-making processes. Through the HerzMobil case study, improvements in patient self-management and reductions in hospital readmission rates have been observed, showcasing the successful application of telehealth in chronic disease manage...
Source: Studies in Health Technology and Informatics - April 29, 2024 Category: Information Technology Authors: Hillary Farmer Karl Kreiner Thomas Sch ütz Gerhard P ölzl Christian Puelacher G ünter Schreier Source Type: research

Causal association of metformin treatment with diverse cardiovascular diseases: a Mendelian randomization analysis
CONCLUSION: The MR study discovered from a genetic standpoint that metformin may lower the risk of hypertrophic cardiomyopathy and valvular heart disease, yet it could elevate the risk of myocardial infarction.PMID:38683129 | DOI:10.18632/aging.205775 (Source: Aging)
Source: Aging - April 29, 2024 Category: Biomedical Science Authors: Kaiyuan Li Peng Liu Jun Ye Miao Liu Li Zhu Source Type: research

Sodium-Glucose Cotransporter-2 Inhibitors and the Risk for Dialysis and Cardiovascular Disease in Patients With Stage 5 Chronic Kidney Disease
CONCLUSION: This emulated target trial showed that SGLT2i use was associated with a lower risk for dialysis, cardiovascular events, DKA, and AKI than no SGLT2i use in patients with T2D and stage 5 CKD.PRIMARY FUNDING SOURCE: National Health Research Institutes, Taiwan.PMID:38684099 | DOI:10.7326/M23-1874 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 29, 2024 Category: Internal Medicine Authors: Fu-Shun Yen Chii-Min Hwu Jia-Sin Liu Yi-Ling Wu Keong Chong Chih-Cheng Hsu Source Type: research

The Evolution of Telehealth in Heart Failure Management: The Role of Large Language Models and HerzMobil as a Potential Use Case
This study examines the integration of LLMs in heart failure management, with a focus on HerzMobil as a pioneering telehealth program. The technical underpinnings of LLMs, their current applications in the medical field, and their potential to enhance telehealth services, have been explored. The paper highlights the benefits of LLMs in patient interaction, clinical documentation, and decision-making processes. Through the HerzMobil case study, improvements in patient self-management and reductions in hospital readmission rates have been observed, showcasing the successful application of telehealth in chronic disease manage...
Source: Studies in Health Technology and Informatics - April 29, 2024 Category: Information Technology Authors: Hillary Farmer Karl Kreiner Thomas Sch ütz Gerhard P ölzl Christian Puelacher G ünter Schreier Source Type: research

HerzMobil Tirol PreOp - A Multidisciplinary Telemonitoring Project for Heart Failure Patients Prior to Cardiac Surgery
CONCLUSION: Design of the first preoperative telemonitoring-assisted optimisation project for high-risk patients undergoing cardiac surgery.PMID:38682519 | DOI:10.3233/SHTI240026 (Source: Studies in Health Technology and Informatics)
Source: Studies in Health Technology and Informatics - April 29, 2024 Category: Information Technology Authors: Karin Hinterbuchner Elisabeth Kleinheinz Bettina Fetz Leo P ölzl Johannes Holfeld Bernhard Pfeifer Sabrina Neururer Christian Puelacher Can Gollmann-Tepekoeylue Susanne Krestan Andreas Huber Gerhard P ölzl Source Type: research

Exploring the Environmental Impact of Telemedicine: A Life Cycle Assessment
DISCUSSION: Given the frequent car travels, telemedicine emerges as a tool to improve environmental benefits and reduce time for patients and caregivers.PMID:38682509 | DOI:10.3233/SHTI240016 (Source: Studies in Health Technology and Informatics)
Source: Studies in Health Technology and Informatics - April 29, 2024 Category: Information Technology Authors: Anna Savoldelli Daniele Landi Caterina Rizzi Source Type: research

Cellular Senescence as a Targetable Risk Factor for Cardiovascular Diseases: Therapeutic Implications: < em > JACC < /em > Family Series
JACC Basic Transl Sci. 2024 Apr 8;9(4):522-534. doi: 10.1016/j.jacbts.2023.12.003. eCollection 2024 Apr.ABSTRACTThe prevalence of cardiovascular diseases markedly rises with age. Cellular senescence, a hallmark of aging, is characterized by irreversible cell cycle arrest and the manifestation of a senescence-associated secretory phenotype, which has emerged as a significant contributor to aging, mortality, and a spectrum of chronic ailments. An increasing body of preclinical and clinical research has established connections between senescence, senescence-associated secretory phenotype, and age-related cardiac and vascular ...
Source: Atherosclerosis - April 29, 2024 Category: Cardiology Authors: Manish Kumar Pengyi Yan George A Kuchel Ming Xu Source Type: research

Plasma SMOC2 Predicts Prognosis in Patients with Heart Failure: A Prospective Cohort
(Source: International Journal of General Medicine)
Source: International Journal of General Medicine - April 29, 2024 Category: General Medicine Tags: International Journal of General Medicine Source Type: research

TYG Index as a Novel Predictor of Clinical Outcomes in Advanced Chronic Heart Failure with Renal Dysfunction Patients
(Source: Clinical Interventions in Aging)
Source: Clinical Interventions in Aging - April 29, 2024 Category: Geriatrics Tags: Clinical Interventions in Aging Source Type: research

Multidisciplinary care of peripartum heart failure: A scientific statement of the Heart Failure Association of the ESC
AbstractHeart failure is the most common cardiovascular complication during pregnancy and the postpartum period. It is associated with increased risk of maternal morbidity and mortality as well as potentially life-threatening foetal pathology. Management of heart failure in pregnancy requires expert knowledge of cardiovascular disease as well as obstetrics which underscores the importance of multidisciplinary cardio-obstetrics teams in order to optimize diagnosis, treatment and outcome. This includes counselling of women at risk before and during the course of pregnancy in order to strengthen the relationship between medic...
Source: European Journal of Heart Failure - April 29, 2024 Category: Cardiology Authors: Amina Rakisheva, Karen Sliwa, Johann Bauersachs, Sophie Van Linthout, Vijay K. Chopra, Antoni Bayes ‐Genis, Franca Fruzzetti, Antonio Cannatà, Benjamin Deniau, Alexandre Mebazaa, Gianluigi Savarese, Robin Ray, Cristiana Vitale, Marco Metra Tags: Position Paper Source Type: research

Subclinical systolic dysfunction in genotype ‐positive phenotype‐negative relatives of dilated cardiomyopathy patients: A systematic review and meta‐analysis
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - April 29, 2024 Category: Cardiology Authors: Andrea Faggiano, Elisa Gherbesi, Eleonora Gnan, Alessia Paldino, Marco Merlo, Gianfranco Sinagra, Stefano Carugo Tags: Research Letter Source Type: research