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Herpes Simplex Virus: A Practical Guide to Diagnosis, Management, and Patient Counseling for the Primary Care Clinician
Med Clin North Am. 2024 Mar;108(2):311-323. doi: 10.1016/j.mcna.2023.08.016. Epub 2023 Oct 8.ABSTRACTGenital herpes is a chronic, lifelong sexually transmitted viral infection, which can cause recurrent, self-limited genital ulcers. It is caused by herpes simplex virus (HSV) type 1 and type 2 viruses. Genital HSV infection is a very prevalent STI, which causes self-limited, recurrent genital ulcers. Treatment decreases duration of symptoms and signs and can be provided as episodic or suppressive therapy. Genital herpes can have a substantial impact during pregnancy and on sexual health in general. Counseling on natural his...
Source: The Medical Clinics of North America - February 8, 2024 Category: General Medicine Authors: Teresa A Batteiger Cornelis A Rietmeijer Source Type: research

Integration of network pharmacology with experimental validation to reveal the mechanism of action of Longdan Xiegan Decoction against HSV2 infection and determine its effective components
CONCLUSION: LCB acted as the main component of LXD, with significant anti-HSV2 infection effects both in vivo and in vitro. This study provides additional evidence of the healing efficacy of LXD against HSV infection and presents an efficient analytical method for further investigation of the mechanisms of TCM in prevention and treatment of various diseases.PMID:38316223 | DOI:10.1016/j.jep.2024.117861 (Source: Herpes)
Source: Herpes - February 5, 2024 Category: Infectious Diseases Authors: Yuyun Li Siyan Li Zeren Shou Yibin Li Axin Li Wenli Liu Xin Zhang Chengliang Zhou Daohua Xu Lin Li Source Type: research

Anorectal Mpox in men who have sex with men associated with sexually transmitted co-infections: a case series
Since May 2022, there has been an outbreak of Mpox in the UK, alongside Europe and the USA, mainly associated with sexual contact among men who have sex with men (MSM).1 The majority of individuals with Mpox experience mild or moderate genital, anorectal and systemic symptoms, followed by complete recovery.1 Overall, published data suggest that 11%–44% of patients present with anorectal symptoms.1–3 In Brighton, we have a large population of MSM and gender diverse people, including ~2500 people using HIV-pre-exposure prophylaxis (HIV-PrEP) who access our sexual health clinics. Patients who present with possible...
Source: Sexually Transmitted Infections - January 17, 2024 Category: Sexual Medicine Authors: Russell, A., Siddiq, M., Fitzpatrick, C., Richardson, D. Tags: PostScript Source Type: research

Overview of Vaginal Ulcerative Disease
Pediatr Ann. 2024 Jan;53(1):e10-e16. doi: 10.3928/19382359-20231113-03. Epub 2024 Jan 1.ABSTRACTGenital ulcers may be located on the vagina, penis, and anorectal or perineal areas and may be infectious or noninfectious. Vaginal ulcers affect patients of all ages and are commonly due to sexually transmitted infections, such as herpes simplex virus, the most common cause of genital ulcers in the United States. Non-sexually transmitted infections, such as Epstein-Barr virus, and other noninfectious causes, such as trauma, medications, and autoimmune disease, rarely can present with genital ulcers. Appropriate history, examina...
Source: Pediatric Annals - January 9, 2024 Category: Pediatrics Authors: Cherie Priya Dhar Jessica L Feuerstein Caroline Salas-Humara Source Type: research