Exploring the association between erythema multiforme and HIV infection: some mechanisms and implications
This article highlights the potential direct and indirect role that HIV infection may play in the development of EM and the clinical dilemma that arises in the management of HIV-infected patients with this condition. These patients may require additional medications to manage opportunistic infections, many of which can also trigger hypersensitivity reactions leading to EM.PMID:38637892 | PMC:PMC11027329 | DOI:10.1186/s12981-024-00607-6 (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - April 18, 2024 Category: Infectious Diseases Authors: Shumani Charlotte Manenzhe Razia Abdool Gafaar Khammissa Sindisiwe Londiwe Shangase Mia Michaela Beetge Source Type: research
Exploring the association between erythema multiforme and HIV infection: some mechanisms and implications
This article highlights the potential direct and indirect role that HIV infection may play in the development of EM and the clinical dilemma that arises in the management of HIV-infected patients with this condition. These patients may require additional medications to manage opportunistic infections, many of which can also trigger hypersensitivity reactions leading to EM.PMID:38637892 | PMC:PMC11027329 | DOI:10.1186/s12981-024-00607-6 (Source: Herpes)
Source: Herpes - April 18, 2024 Category: Infectious Diseases Authors: Shumani Charlotte Manenzhe Razia Abdool Gafaar Khammissa Sindisiwe Londiwe Shangase Mia Michaela Beetge Source Type: research
Exploring the association between erythema multiforme and HIV infection: some mechanisms and implications
This article highlights the potential direct and indirect role that HIV infection may play in the development of EM and the clinical dilemma that arises in the management of HIV-infected patients with this condition. These patients may require additional medications to manage opportunistic infections, many of which can also trigger hypersensitivity reactions leading to EM.PMID:38637892 | PMC:PMC11027329 | DOI:10.1186/s12981-024-00607-6 (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - April 18, 2024 Category: Infectious Diseases Authors: Shumani Charlotte Manenzhe Razia Abdool Gafaar Khammissa Sindisiwe Londiwe Shangase Mia Michaela Beetge Source Type: research
Aetiological molecular identification of sexually transmitted infections that cause urethral discharge syndrome and genital ulcer disease in Brazilian men: a nationwide study
Conclusion
This study provided the acquisition of unprecedented data on the aetiology of UDS and GUD in Brazil, demonstrated the presence of a variety of pathogens in both sample types and reaffirmed the aetiologies known to be most prevalent globally. (Source: Sexually Transmitted Infections)
Source: Sexually Transmitted Infections - April 18, 2024 Category: Sexual Medicine Authors: Bazzo, M. L., Machado, H. d. M., Martins, J. M., Schörner, M. A., Buss, K., Barazzetti, F. H., Gaspar, P. C., Bigolin, A., Benzaken, A., de Carvalho, S. V. F., Andrade, L. d. F., Ferreira, W. A., Figueiroa, F., Fontana, R. M., da Silva, M. F. d. C Tags: Original research Source Type: research
Management of Oral Manifestations of Herpes Simplex Virus, Varicella Zoster Virus, and Human Papillomavirus
Compend Contin Educ Dent. 2024 Apr;45(4):192-197; quiz 198.ABSTRACTHuman herpes virus is a family of DNA viruses that includes herpes simplex virus (HSV) and varicella zoster virus (VZV). HSV-1 and HSV-2 are fairly common and result in oral and genital lesions. Recurrent infections of herpes include lesions on the lips resulting in pain and possibly societal stigma, making adequate treatment of these conditions crucial. VZV is the cause of chicken pox and shingles. Acyclovir and other nucleoside analogues have been the gold standard of treatment for HSV and VZV, but newer, more effective treatments are being developed, whi...
Source: Herpes - April 15, 2024 Category: Infectious Diseases Authors: Lauren Elkada Aviv Ouanounou Source Type: research
Demographic and clinical characteristics of people diagnosed with active sexually transmitted infections among monkeypox cases in Brazil: the 2022 outbreak
Rev Inst Med Trop Sao Paulo. 2024 Apr 5;66:e20. doi: 10.1590/S1678-9946202466020. eCollection 2024.ABSTRACTThe worldwide monkeypox (mpox) outbreak in 2022 showed a high frequency of sexually transmitted infections (STI). A cross-sectional study was carried out using secondary data from the Brazilian official mpox surveillance systems. A total of 10,169 mpox cases were identified, with a median age of 32 years. Among them, 92.3% were male at birth and 57.5% were men who have sex with other men (MSM). Approximately 11% were diagnosed with STI, including 5.8% with syphilis and 2.5% with genital herpes. Individuals aged from 2...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - April 10, 2024 Category: Tropical Medicine Authors: Isabella Nepomuceno de Souza Ana Roberta Pati Pascom Matheus Funke Spinelli Guilherme Borges Dias Draurio Barreira Ang élica Espinosa Miranda Source Type: research
Demographic and clinical characteristics of people diagnosed with active sexually transmitted infections among monkeypox cases in Brazil: the 2022 outbreak
Rev Inst Med Trop Sao Paulo. 2024 Apr 5;66:e20. doi: 10.1590/S1678-9946202466020. eCollection 2024.ABSTRACTThe worldwide monkeypox (mpox) outbreak in 2022 showed a high frequency of sexually transmitted infections (STI). A cross-sectional study was carried out using secondary data from the Brazilian official mpox surveillance systems. A total of 10,169 mpox cases were identified, with a median age of 32 years. Among them, 92.3% were male at birth and 57.5% were men who have sex with other men (MSM). Approximately 11% were diagnosed with STI, including 5.8% with syphilis and 2.5% with genital herpes. Individuals aged from 2...
Source: Herpes - April 10, 2024 Category: Infectious Diseases Authors: Isabella Nepomuceno de Souza Ana Roberta Pati Pascom Matheus Funke Spinelli Guilherme Borges Dias Draurio Barreira Ang élica Espinosa Miranda Source Type: research
Demographic and clinical characteristics of people diagnosed with active sexually transmitted infections among monkeypox cases in Brazil: the 2022 outbreak
Rev Inst Med Trop Sao Paulo. 2024 Apr 5;66:e20. doi: 10.1590/S1678-9946202466020. eCollection 2024.ABSTRACTThe worldwide monkeypox (mpox) outbreak in 2022 showed a high frequency of sexually transmitted infections (STI). A cross-sectional study was carried out using secondary data from the Brazilian official mpox surveillance systems. A total of 10,169 mpox cases were identified, with a median age of 32 years. Among them, 92.3% were male at birth and 57.5% were men who have sex with other men (MSM). Approximately 11% were diagnosed with STI, including 5.8% with syphilis and 2.5% with genital herpes. Individuals aged from 2...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - April 10, 2024 Category: Tropical Medicine Authors: Isabella Nepomuceno de Souza Ana Roberta Pati Pascom Matheus Funke Spinelli Guilherme Borges Dias Draurio Barreira Ang élica Espinosa Miranda Source Type: research
Demographic and clinical characteristics of people diagnosed with active sexually transmitted infections among monkeypox cases in Brazil: the 2022 outbreak
Rev Inst Med Trop Sao Paulo. 2024 Apr 5;66:e20. doi: 10.1590/S1678-9946202466020. eCollection 2024.ABSTRACTThe worldwide monkeypox (mpox) outbreak in 2022 showed a high frequency of sexually transmitted infections (STI). A cross-sectional study was carried out using secondary data from the Brazilian official mpox surveillance systems. A total of 10,169 mpox cases were identified, with a median age of 32 years. Among them, 92.3% were male at birth and 57.5% were men who have sex with other men (MSM). Approximately 11% were diagnosed with STI, including 5.8% with syphilis and 2.5% with genital herpes. Individuals aged from 2...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - April 10, 2024 Category: Tropical Medicine Authors: Isabella Nepomuceno de Souza Ana Roberta Pati Pascom Matheus Funke Spinelli Guilherme Borges Dias Draurio Barreira Ang élica Espinosa Miranda Source Type: research
Demographic and clinical characteristics of people diagnosed with active sexually transmitted infections among monkeypox cases in Brazil: the 2022 outbreak
Rev Inst Med Trop Sao Paulo. 2024 Apr 5;66:e20. doi: 10.1590/S1678-9946202466020. eCollection 2024.ABSTRACTThe worldwide monkeypox (mpox) outbreak in 2022 showed a high frequency of sexually transmitted infections (STI). A cross-sectional study was carried out using secondary data from the Brazilian official mpox surveillance systems. A total of 10,169 mpox cases were identified, with a median age of 32 years. Among them, 92.3% were male at birth and 57.5% were men who have sex with other men (MSM). Approximately 11% were diagnosed with STI, including 5.8% with syphilis and 2.5% with genital herpes. Individuals aged from 2...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - April 10, 2024 Category: Tropical Medicine Authors: Isabella Nepomuceno de Souza Ana Roberta Pati Pascom Matheus Funke Spinelli Guilherme Borges Dias Draurio Barreira Ang élica Espinosa Miranda Source Type: research
Demographic and clinical characteristics of people diagnosed with active sexually transmitted infections among monkeypox cases in Brazil: the 2022 outbreak
Rev Inst Med Trop Sao Paulo. 2024 Apr 5;66:e20. doi: 10.1590/S1678-9946202466020. eCollection 2024.ABSTRACTThe worldwide monkeypox (mpox) outbreak in 2022 showed a high frequency of sexually transmitted infections (STI). A cross-sectional study was carried out using secondary data from the Brazilian official mpox surveillance systems. A total of 10,169 mpox cases were identified, with a median age of 32 years. Among them, 92.3% were male at birth and 57.5% were men who have sex with other men (MSM). Approximately 11% were diagnosed with STI, including 5.8% with syphilis and 2.5% with genital herpes. Individuals aged from 2...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - April 10, 2024 Category: Tropical Medicine Authors: Isabella Nepomuceno de Souza Ana Roberta Pati Pascom Matheus Funke Spinelli Guilherme Borges Dias Draurio Barreira Ang élica Espinosa Miranda Source Type: research
Demographic and clinical characteristics of people diagnosed with active sexually transmitted infections among monkeypox cases in Brazil: the 2022 outbreak
Rev Inst Med Trop Sao Paulo. 2024 Apr 5;66:e20. doi: 10.1590/S1678-9946202466020. eCollection 2024.ABSTRACTThe worldwide monkeypox (mpox) outbreak in 2022 showed a high frequency of sexually transmitted infections (STI). A cross-sectional study was carried out using secondary data from the Brazilian official mpox surveillance systems. A total of 10,169 mpox cases were identified, with a median age of 32 years. Among them, 92.3% were male at birth and 57.5% were men who have sex with other men (MSM). Approximately 11% were diagnosed with STI, including 5.8% with syphilis and 2.5% with genital herpes. Individuals aged from 2...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - April 10, 2024 Category: Tropical Medicine Authors: Isabella Nepomuceno de Souza Ana Roberta Pati Pascom Matheus Funke Spinelli Guilherme Borges Dias Draurio Barreira Ang élica Espinosa Miranda Source Type: research
Demographic and clinical characteristics of people diagnosed with active sexually transmitted infections among monkeypox cases in Brazil: the 2022 outbreak
Rev Inst Med Trop Sao Paulo. 2024 Apr 5;66:e20. doi: 10.1590/S1678-9946202466020. eCollection 2024.ABSTRACTThe worldwide monkeypox (mpox) outbreak in 2022 showed a high frequency of sexually transmitted infections (STI). A cross-sectional study was carried out using secondary data from the Brazilian official mpox surveillance systems. A total of 10,169 mpox cases were identified, with a median age of 32 years. Among them, 92.3% were male at birth and 57.5% were men who have sex with other men (MSM). Approximately 11% were diagnosed with STI, including 5.8% with syphilis and 2.5% with genital herpes. Individuals aged from 2...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - April 10, 2024 Category: Tropical Medicine Authors: Isabella Nepomuceno de Souza Ana Roberta Pati Pascom Matheus Funke Spinelli Guilherme Borges Dias Draurio Barreira Ang élica Espinosa Miranda Source Type: research
Demographic and clinical characteristics of people diagnosed with active sexually transmitted infections among monkeypox cases in Brazil: the 2022 outbreak
Rev Inst Med Trop Sao Paulo. 2024 Apr 5;66:e20. doi: 10.1590/S1678-9946202466020. eCollection 2024.ABSTRACTThe worldwide monkeypox (mpox) outbreak in 2022 showed a high frequency of sexually transmitted infections (STI). A cross-sectional study was carried out using secondary data from the Brazilian official mpox surveillance systems. A total of 10,169 mpox cases were identified, with a median age of 32 years. Among them, 92.3% were male at birth and 57.5% were men who have sex with other men (MSM). Approximately 11% were diagnosed with STI, including 5.8% with syphilis and 2.5% with genital herpes. Individuals aged from 2...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - April 10, 2024 Category: Tropical Medicine Authors: Isabella Nepomuceno de Souza Ana Roberta Pati Pascom Matheus Funke Spinelli Guilherme Borges Dias Draurio Barreira Ang élica Espinosa Miranda Source Type: research
Therapeutic prime/pull vaccination of HSV-2-infected guinea pigs with the ribonucleotide reductase 2 (RR2) protein and CXCL11 chemokine boosts antiviral local tissue-resident and effector memory CD4(+) and CD8(+) T cells and protects against recurrent genital herpes
In this study, we used the strategy that involves immunization of herpes simplex virus type 2-infected guinea pigs using a recombinantly expressed herpes tegument protein-ribonucleotide reductase 2 (RR2; prime), followed by intravaginal treatment with the neurotropic adeno-associated virus type 8 expressing CXCL9, CXCL10, or CXCL11 T-cell-attracting chemokines to recruit T cells into the infected dorsal root ganglia (DRG) and vaginal mucosa (VM) (pull). We show that the RR2/CXCL11 prime-pull therapeutic vaccine strategy elicited a significant reduction in virus shedding in the vaginal mucosa and decreased the severity and ...
Source: Herpes - April 8, 2024 Category: Infectious Diseases Authors: Afshana Quadiri Swayam Prakash Nisha Rajeswari Dhanushkodi Mahmoud Singer Latifa Zayou Amin Mohammed Shaik Miyo Sun Berfin Suzer Lauren Su Lin Lau Amruth Chilukurri Hawa Vahed Hubert Schaefer Lbachir BenMohamed Source Type: research
