Quality assessment on Polygoni Multiflori Caulis using HPLC/UV/MS combined with principle component analysis
Conclusion:
The finding provides a scientific basis for collecting Polygoni Multiflori Caulis in the best time. Moreover, the diameter can be used as the criterion for quality control on Polygoni Multiflori Caulis as a preliminary step in the future. In addition, scores plot obtained from principal component analysis shows the obvious differences between unqualified Polygoni Multiflori Caulis samples and qualified ones visually, which can be used to single out the unqualified ones with qualified ones efficiently and immediately. (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - June 24, 2013 Category: Chemistry Authors: Yang ZhaoChun-Pin KaoYuan-Shiun ChangYu-Ling Ho Source Type: research
Polygonum multiflorum: Toxic hepatitis: case report
(Source: Reactions)
Source: Reactions - February 26, 2013 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Proteomic analysis for anti-atherosclerotic effect of tetrahydroxystilbene glucoside in rats.
In conclusion, TSG treatment suppresses atherosclerosis by altering the expression of different proteins. Calreticulin, vimentin, HSP 70, lipocortin 1, and Apo A-I, are key proteins that may be novel molecular targets responsible for atherogenesis suppression induced by TSG treatment.
PMID: 23206751 [PubMed - as supplied by publisher] (Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie)
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - November 15, 2012 Category: Drugs & Pharmacology Authors: Yao W, Fan W, Huang C, Zhong H, Chen X, Zhang W Tags: Biomed Pharmacother Source Type: research
Tetrahydroxystilbene glucoside improves the learning and memory of amyloid-β(1-42)-injected rats and may be connected to synaptic changes in the hippocampus.
Abstract
The aim of this study was to evaluate the protective effects of 2,3,5,4'-tetrahydroxystilbene-2-O-β-d-glucoside (TSG), an active component extracted from Polygonum multiflorum, on learning/memory deficits in Alzheimer's disease (AD). We randomly divided 24 male Sprague-Dawley rats among 4 groups: (i) the sham-operated group (control); (ii) sham-operated group also treated with TSG (sham+TSG); (iii) beta amyloid treated group (Aβ); and (iv) Aβ treatment group also treated with TSG (Aβ+TSG). Rats in the Aβ and Aβ+TSG groups were treated with Aβ(1-42) intracerebroventricularly, whereas the con...
Source: Canadian Journal of Physiology and Pharmacology - November 1, 2012 Category: Drugs & Pharmacology Authors: Zhou L, Hou Y, Yang Q, Du X, Li M, Yuan M, Zhou Z Tags: Can J Physiol Pharmacol Source Type: research
