Canadian Journal of Physiology and Pharmacology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Psychological interventions targeting mental health and stress among females with cardiac disease: a scoping review
Can J Physiol Pharmacol. 2024 Apr 8. doi: 10.1139/cjpp-2023-0416. Online ahead of print.ABSTRACTInterventions that target mental health symptoms and stress among those with established cardiac disease have included predominately male samples despite female patients reporting greater severity of these symptoms. The aim of this scoping review was to synthesize the published literature on psychological interventions for females with cardiac disease. We conducted a systematic search of peer-reviewed randomized clinical trials (RCTs) published in the English language from 2003 to 2023, in three databases: Medline (Ovid), PsycIn...
Source: Canadian Journal of Physiology and Pharmacology - April 8, 2024 Category: Drugs & Pharmacology Authors: Stephanie Susinski Karen Bouchard Elisa Stragapede Sophie Dozois Evan Sterling Heather Tulloch Source Type: research

Discontinuing semaglutide after weight loss: strategy for weight maintenance and a possible new side effect
We reported the case of a 35-year-old male prescribed oral semaglutide with 22.7 kg weight loss over 120 days. Herein, we describe the clinical course when discontinuing GLP-1 RA therapy, one approach to maintaining weight loss after discontinuation, and a possible new side effect. At day 120, we continued oral semaglutide 7 mg daily, down from 14 mg, for weight maintenance with subsequent weight regain. We re-increased semaglutide to 14 mg/day with weight re-loss within 1 month and weight maintance for a year. We then discontinued semaglutide; weight loss was maintained for 6 months. The patient reported lactose intoleran...
Source: Canadian Journal of Physiology and Pharmacology - April 8, 2024 Category: Drugs & Pharmacology Authors: Nicholas W Carris Shawn Wallace Christopher G DuCoin Rahul Mhaskar Marilyn Stern Brian Bunnell Source Type: research

Cardio-rheumatology: the cardiovascular, pharmacological, and surgical risks associated with rheumatological diseases in women
Can J Physiol Pharmacol. 2024 Mar 15. doi: 10.1139/cjpp-2023-0420. Online ahead of print.ABSTRACTCardiovascular disease (CVD) remains the number one cause of death worldwide. Women are at increased risk of death from CVD, but the mechanisms for how and why this occurs remain elusive. One subset of women who are exceptionally vulnerable to CVD are those with rheumatic diseases (RDs). Indeed, women account for 80% of all RDs, disorders that encompass a broad range of autoimmune and autoinflammatory diseases that lead to chronic inflammation and pathology. The clear association of increased CVD risk in women with RD is though...
Source: Canadian Journal of Physiology and Pharmacology - March 15, 2024 Category: Drugs & Pharmacology Authors: Samantha Le Sommer Maria Irene Kontaridis Source Type: research

Sex-specific effects of frailty on cardiac structure and function: Insights from preclinical models
Can J Physiol Pharmacol. 2024 Mar 15. doi: 10.1139/cjpp-2024-0009. Online ahead of print.ABSTRACTAdvanced age is an independent risk factor for cardiovascular diseases in both sexes. This is thought to be due, in part, to age-dependent cellular, structural, and functional changes in the heart, a process known as cardiac aging. An emerging view is that cardiac aging leads to the accumulation of cellular and subcellular deficits that increase susceptibility to cardiovascular diseases. Still, people age at different rates, with those aging rapidly considered frail. Evidence suggests that frailty, rather than simply age, is a ...
Source: Canadian Journal of Physiology and Pharmacology - March 15, 2024 Category: Drugs & Pharmacology Authors: Elise S Bisset Susan E Howlett Source Type: research