Herb-induced liver injury related to Reynoutria multiflora (Thunb.) moldenke: risk factors, molecular and mechanistic specifics - Zhai XR, Zou ZS, Wang JB, Xiao XH.
Herbal medicine is widely used in Asia as well as the west. Hepatotoxicity is one of the most severe side effects of herbal medicine which is an increasing concern around the world. Reynoutria multiflora (Thunb.) Moldenke (Polygonum multiflorum Thunb., PM)... (Source: SafetyLit)
Source: SafetyLit - September 22, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Risk profiling using metabolomic characteristics for susceptible individuals of drug-induced liver injury caused by Polygonum multiflorum - Zhang L, Niu M, Wei AW, Tang JF, Tu C, Bai ZF, Zou ZS, Xiao XH, Liu YP, Wang JB.
Polygonum multiflorum Thunb. (PMT), officially listed in the Chinese Pharmacopoeia, is one of the most popular perennial Chinese traditional medicines known as He shou wu in China and East Asia, and as Fo-ti in North America.
Idiosyncratic drug-induced ... (Source: SafetyLit)
Source: SafetyLit - October 26, 2019 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Features of He Shou Wu-induced Liver Injury Features of He Shou Wu-induced Liver Injury
He Shou Wu, a Chinese herb used since ancient times as an anti-aging remedy and all-around health tonic, can result in severe, sometimes fatal liver injury.Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 18, 2019 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news
Evidence chain-based causality identification in herb-induced liver injury: exemplification of a well-known liver-restorative herb Polygonum multiflorum - Wang J, Ma Z, Niu M, Zhu Y, Liang Q, Zhao Y, Song J, Bai Z, Zhang Y, Zhang P, Li N, Meng Y, Li Q, Qin L, Teng G, Cao J, Li B, Chen S, Li Y, Zou Z, Zhou H, Xiao X.
Herbal medicines have recently been recognized as the second most common cause of drug-induced liver injury (DILI) in the United States. However, reliable methods to identify the DILI causality of some herbs, such as Heshouwu (dried root of Polygonum multi... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - October 21, 2015 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news
Eighteen cases of liver injury following ingestion of Polygonum multiflorum - Dong H, Slain D, Cheng J, Ma W, Liang W.
OBJECTIVES: Polygonum multiflorum is a popular Chinese herbal medication. In this case series, we report on 18 otherwise healthy non-viral hepatitis patients who developed liver dysfunction following consumption of P. multiflorum alone. METHODS: Concurrent... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - February 28, 2014 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news
Potential To Prevent And Treat Alzheimer's Disease Offered By Novel Herbal Compound
Administration of the active compound tetrahydroxystilbene glucoside (TSG) derived from the Chinese herbal medicine Polygonum multiflorum Thunb, reversed both overexpression of α-synuclein, a small protein found in the brain, and its accumulation using a mouse model of Alzheimer's disease. These results, which may shed light on the neuropathology of AD and open up new avenues of treatment, are available in the current issue of Restorative Neurology and Neuroscience... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 19, 2013 Category: Consumer Health News Tags: Alzheimer's / Dementia Source Type: news
Novel herbal compound offers potential to prevent and treat Alzheimer's disease
(IOS Press) Administration of the active compound tetrahydroxystilbene glucoside derived from the Chinese herbal medicine Polygonum multiflorum Thunb, reversed both overexpression of α-synuclein, a small protein found in the brain, and its accumulation using a mouse model of Alzheimer's disease. These results, which may shed light on the neuropathology of AD and open up new avenues of treatment, are available in the current issue of Restorative Neurology and Neuroscience. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 15, 2013 Category: Global & Universal Source Type: news
