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Evidence chain-based causality identification in herb-induced liver injury: exemplification of a well-known liver-restorative herb Polygonum multiflorum - Wang J, Ma Z, Niu M, Zhu Y, Liang Q, Zhao Y, Song J, Bai Z, Zhang Y, Zhang P, Li N, Meng Y, Li Q, Qin L, Teng G, Cao J, Li B, Chen S, Li Y, Zou Z, Zhou H, Xiao X.
Herbal medicines have recently been recognized as the second most common cause of drug-induced liver injury (DILI) in the United States. However, reliable methods to identify the DILI causality of some herbs, such as Heshouwu (dried root of Polygonum multi... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - October 21, 2015 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Eighteen cases of liver injury following ingestion of Polygonum multiflorum - Dong H, Slain D, Cheng J, Ma W, Liang W.
OBJECTIVES: Polygonum multiflorum is a popular Chinese herbal medication. In this case series, we report on 18 otherwise healthy non-viral hepatitis patients who developed liver dysfunction following consumption of P. multiflorum alone. METHODS: Concurrent... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - February 28, 2014 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Potential To Prevent And Treat Alzheimer's Disease Offered By Novel Herbal Compound
Administration of the active compound tetrahydroxystilbene glucoside (TSG) derived from the Chinese herbal medicine Polygonum multiflorum Thunb, reversed both overexpression of α-synuclein, a small protein found in the brain, and its accumulation using a mouse model of Alzheimer's disease. These results, which may shed light on the neuropathology of AD and open up new avenues of treatment, are available in the current issue of Restorative Neurology and Neuroscience... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 19, 2013 Category: Consumer Health News Tags: Alzheimer's / Dementia Source Type: news

Novel herbal compound offers potential to prevent and treat Alzheimer's disease
(IOS Press) Administration of the active compound tetrahydroxystilbene glucoside derived from the Chinese herbal medicine Polygonum multiflorum Thunb, reversed both overexpression of α-synuclein, a small protein found in the brain, and its accumulation using a mouse model of Alzheimer's disease. These results, which may shed light on the neuropathology of AD and open up new avenues of treatment, are available in the current issue of Restorative Neurology and Neuroscience. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 15, 2013 Category: Global & Universal Source Type: news