Colorimetric sensor array for versatile detection and discrimination of model analytes with environmental relevance
In the current work, a rapid, simple, low-cost, and sensitive smartphone-based colorimetric sensor array coupled with pattern-recognition methods was proposed for the determination and differentiation of some ... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - April 22, 2024 Category: Chemistry Authors: Mina Adampourezare, Behzad Nikzad, Sanaz Sajedi-Amin and Elaheh Rahimpour Tags: Research Source Type: research
Modified nano magnetic Fe2O3-MgO as a high active multifunctional heterogeneous catalyst for environmentally beneficial carbon –carbon synthesis
In this study, novel nanomagnetic catalysts, namely Fe2O3-MgO@choline formate (Ch. F.) and Fe2O3-MgO@choline cyanide (Ch. CN), were synthesized through immobilizing choline-based ion liquids to magnetic support v... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - April 20, 2024 Category: Chemistry Authors: Ehsan Kamali, Fahim Dreekvandy, Abolfazl Mohammadkhani and Akbar Heydari Tags: Research Source Type: research
Poly (aniline-co-aniline-2,5-disulfonic acid) / L-ascorbic acid / Ag@SiO2 / polysafranin nanocomposite: synthesis, characterization and anomalous electrical behaviour
We report the synthesis of sulfonated copolyaniline/polysafranin/L-ascorbic acid/Ag@SiO2 fine powdered nanocomposites and investigate the influence of incorporating the dye on their conductivity. The composite wa... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - April 20, 2024 Category: Chemistry Authors: Hammed H. A. M. Hassan, Marwa Abdel Fattah and Fatma Abdel Maged Tags: Research Source Type: research
Identification of new potent NLRP3 inhibitors by multi-level in-silico approaches
Nod-like receptor protein 3 (NLRP-3), is an intracellular sensor that is involved in inflammasome activation, and the aberrant expression of NLRP3 is responsible for diabetes mellitus, its complications, and m... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - April 18, 2024 Category: Chemistry Authors: Chandni Hayat, Vetriselvan Subramaniyan, Mubarak A. Alamri, Ling Shing Wong, Asaad Khalid, Ashraf N. Abdalla, Sahib Gul Afridi, Vinoth Kumarasamy and Abdul Wadood Tags: Research Source Type: research
In silico identification of phytochemical inhibitors for multidrug-resistant tuberculosis based on novel pharmacophore generation and molecular dynamics simulation studies
Multidrug-resistant tuberculosis (particularly resistant to pyrazinoic acid) is a life-threatening chronic pulmonary disease. Running a marketed regime specifically targets the ribosomal protein subunit-1 (Rps... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - April 18, 2024 Category: Chemistry Authors: Bader S. Alotaibi Tags: Research Source Type: research
Synthesis, characterization, and antibacterial activity studies of two Co(II) complexes with 2-[(E)-(3-acetyl-4-hydroxyphenyl)diazenyl]-4-(2-hydroxyphenyl)thiophene-3-carboxylic acid as a ligand
Two new Cobalt(II) complexes 12 and 13 have been synthesized from 2-[(E)-(3-acetyl-4-hydroxyphenyl)diazenyl]-4-(2-hydroxyphenyl)thiophene-3-carboxylic acid (11) as a novel ligand. These three new compounds were c... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - April 16, 2024 Category: Chemistry Authors: Emmanuel Sopbu é Fondjo, Sorelle Songmi Feuze, Jean-de-Dieu Tamokou, Apollinaire Tsopmo, Giscard Doungmo, Peter Simon Friedrich Wilhelm, Donald Léonel Feugap Tsamo, Bruno Lenta Ndjakou and Jules Roger Kuiate Tags: Research Source Type: research
Hit discovery of potential CDK8 inhibitors and analysis of amino acid mutations for cancer therapy through computer-aided drug discovery
Cyclin-dependent kinase 8 (CDK8) has emerged as a promising target for inhibiting cancer cell function, intensifying efforts towards the development of CDK8 inhibitors as potential cancer therapeutics. Mutatio... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - April 13, 2024 Category: Chemistry Authors: Raziye Aghahasani, Fereshteh Shiri, Hossein Kamaladiny, Fatemeh Haddadi and Somayeh Pirhadi Tags: Research Source Type: research
Development of a stability indicating high-performance liquid chromatography method for determination of cenobamate: study of basic degradation kinetics
This study presents a stability indicating high-performance liquid chromatography HPLC method for the determination of cenobamate (CNB) in presence of its main impurity (CNB H-impurity) and degradation product... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - April 13, 2024 Category: Chemistry Authors: Samah F. EL-Malla, Fotouh R. Mansour, Almoataz Bellah B. Elbastawissy and Samar H. Elagamy Tags: Research Source Type: research
Preparation and characterization of liquefied eggplant branch bio-based controlled-release fertilizer
Bio-based coating materials have received increased attention because of their low-cost, environmentally friendly, and sustainable properties. In this paper, a novel coating material was developed to coat urea... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - April 12, 2024 Category: Chemistry Authors: Yanle Guo, Fengyuan Zhuang, Qunxiang Cui, Shugang Zhang, Zhenping Hao, Yiyun Shi, Hao Lu and Xiaoqing Shi Tags: Research Source Type: research
A theoretical study on toluene oxidization by OH radical
Toluene, a prominent member of volatile organic compounds (VOCs), exerts a substantial adverse influence on both human life and the environment. In the context of advanced oxidation processes, the ·OH radical ... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - April 12, 2024 Category: Chemistry Authors: Yumin Mao, Lijuan Yang, Siqi Liu, Yunchang Song, Mengchao Luo and Yongxue Guo Tags: Research Source Type: research
Reducing the effective dose of cisplatin using cobalt modified silver nano-hybrid as a carriers on MCF7 and HCT cell models
Cancer is a deadly illness with a convoluted pathogenesis. The most prevalent restrictions that frequently result in treatment failure for cancer chemotherapy include lack of selectivity, cytotoxicity, and mul... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - April 10, 2024 Category: Chemistry Authors: Amna H. Faid and Marwa A. Ramadan Tags: Research Source Type: research
Amino-7,8-dihydro-4H-chromenone derivatives as potential inhibitors of acetylcholinesterase and butyrylcholinesterase for Alzheimer ’s disease management; in vitro and in silico study
In this article, we present the design and synthesis of amino-7,8-dihydro-4H-chromenone derivatives as possible inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) for the management of ... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - April 10, 2024 Category: Chemistry Authors: Ali Asadipour, Yaghoub Pourshojaei, Moein Mansouri, Elham Mahdavizadeh, Cambyz Irajie, Javad Mottaghipisheh, Ehsan Faghih-Mirzaei, Mohammad Mahdavi and Aida Iraji Tags: Research Source Type: research
Synthesis, anticancer evaluation, molecular docking and ADME study of novel pyrido[4 ʹ,3ʹ:3,4]pyrazolo[1,5-a]pyrimidines as potential tropomyosin receptor kinase A (TrKA) inhibitors
The starting compound 3-amino-1,7-dihydro-4H-pyrazolo[4,3-c]pyridine-4,6(5H)-dione (1) is reacted with each of diketone and β-ketoester, forming pyridopyrazolo[1,5-a]pyrimidines 4a,b and 14a,b, respectively. The ... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - April 6, 2024 Category: Chemistry Authors: Nadia Hanafy Metwally, Emad Abdullah Deeb and Ibrahim Walid Hasani Tags: Research Source Type: research
Green chemometric-assisted UV-spectrophotometric methods for the determination of favipiravir, cefixime and moxifloxacin hydrochloride as an effective therapeutic combination for COVID-19; application in pharmaceutical form and spiked human plasma
As pharmaceutical analysis progresses towards environmental sustainability, there is a growing need to enhance the safety and health conditions for analysts. Consequently, the incorporation of chemometrics int... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - April 5, 2024 Category: Chemistry Authors: Eman A. Madbouly, Abdalla A. El-Shanawani, Sobhy M. El-adl and Ahmed S. Abdelkhalek Tags: Research Source Type: research
Therapeutic drug monitoring of six contraindicated/co-administered drugs by simple and green RP-HPLC-PDA; application to spiked human plasma
Therapeutic drug monitoring is an important clinical testing of the drugs to monitor their concentrations in plasma in order to guarantee their optimal impact, and to avoid any side effects resulting from drug... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - April 5, 2024 Category: Chemistry Authors: Nada Hesham, Maha A. Hegazy and Hebatallah A. Wagdy Tags: Research Source Type: research
